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| 1 | Influence of Atmospheric Particulate Matter on Ozone in Nanjing,China:Observational Study and Mechanistic Analysis显示文摘Particulate matter with diameters of 2.5 μm or smaller(PM_(2.5)) and ozone(O_3) are major pollutants in the urban atmosphere. PM_(2.5) can affect O_3 by altering the photolysis rate and heterogeneous reactions. However, these two processes and their relative importance remain uncertain. In this paper, with Nanjing in China as the target city, we investigate the characteristics and mechanism of interactions between particles and O_3 based on ground observations and numerical modeling.In 2008, the average concentrations of PM_(2.5) and O_3 at Caochangmen station are 64.6 ± 47.4 μg m^(-3) and 24.6 ± 22.8 ppb,respectively, while at Pukou station they are 94.1 ± 63.4 μg m^(-3) and 16.9 ± 14.9 ppb. The correlation coefficient between PM_(2.5) and O_3 is -0.46. In order to understand the reaction between PM_(2.5) and O_3, we construct a box model, in which an aerosol optical property model, ultraviolet radiation model, gas phase chemistry model, and heterogeneous chemistry model,are coupled. The model is employed to investigate the relative contribution of the aforementioned two processes, which vary under different particle concentrations, scattering capability and VOCs/NOxratios(VOCs: volatile organic compounds;NOx: nitric oxide and nitrogen dioxide). Generally, photolysis rate effect can cause a greater O_3 reduction when the particle concentrations are higher, while heterogeneous reactions dominate O_3 reduction with low-level particle concentrations.Moreover, in typical VOC-sensitive regions, O_3 can even be increased by heterogeneous reactions. In Nanjing, both processes lead to O_3 reduction, and photolysis rate effect is dominant. Our study underscores the importance of photolysis rate effect and heterogeneous reactions for O_3, and such interaction processes should be fully considered in future atmospheric chemistry modeling. | Yawei QU Tijian WANG Yanfeng CAI Shekou WANG Pulong CHEN Shu LI Mengmeng LI Cheng YUAN Jing WANG Shaocai XU | 2018 | Advances in Atmospheric Sciences2018，35，11： | 33 |
| 2 | Direct low-temperature synthesis of graphene on various glasses by plasma-enhanced chemical vapor deposition for versatile, cost-effective electrodes显示文摘在低温度的各种各样的玻璃底层上的 graphene 的没有催化剂、可伸缩的合成具有到象便宜透明电子学和最先进的显示器那样的众多的应用程序的首要的意义。然而,在这个有希望的研究领域以内的系统的学习远这样仍然保持少见。此处,我们用一个低温度的提高血浆的化学蒸汽免职方法在各种各样的眼镜上报导 graphene 的直接生长。如此的一条灵巧、可伸缩的途径在 400600 的一个生长温度范围在各种各样的玻璃底层上保证一致、没有转移的 graphene | Jingyu Sun Yubin Chen Xin Cai Bangjun Ma Zhaolong Chen Manish Kr. Priydarshi Ke Chen Teng Gao Xiuju Song Qingqing Ji Xuefeng Guo Dechun Zou Yanfeng Zhang Zhongfan Liu | 2015 | Nano Research2015，8，11： | 12 |
| 3 | Designing N-doped graphene/ReSe_(2)/Ti_(3)C_(2) MXene heterostructure frameworks as promising anodes for high-rate potassium-ion batteries显示文摘Developing high-performance anodes for potassium ion batteries(KIBs) is of paramount significance but remains challenging.In the normal sense,electrode materials are prepared by ubiquitous wet chemical routes,which otherwise might not be versatile enough to create desired heterostructures and/or form clean interfacial areas for fast transport of K-ions and electrons.Along this line,rate capability/cycling stability of resulting KIBs are greatly handicapped.Herein we present an all-chemical vapor deposition approach to harness the direct synthesis of nitrogen-doped graphene(NG)/rhenium diselenide(ReSe_2)hybrids over three-dimensional MXene supports as superior heterostructure anode material for KIBs.In such an innovative design,1 T'-ReSe2 nanoparticles are sandwiched in between the NG coatings and MXene frameworks via strong interfacial interactions,thereby affording facile K~+ diffusion,enhancing overall conductivity,boosting high-power performance and reinforcing structural stability of electrodes.Thus-constructed anode delivers an excellent rate performance of 138 mAh g^(-1) at 10.0 A g^(-1) and a high reversible capacity of 90 mAh g^(-1) at 5 A g^(-1) after 300 cycles.Furthermore,the potassium storage mechanism has been systematically probed by advanced in situlex situ characterization techniques in combination with first principles computations. | Zhou Xia Xiwen Chen Haina Cia Zhaodi Fan Yuyang Yi Wanjian Yin Nan Wei Jingsheng Cai Yanfeng Zhang Jingyu Sun | 2021 | Journal of Energy Chemistry2021，30，2： | 9 |
| 4 | Wind Tunnel Experiments and Numerical Study on Performance Characteristics of an H-type Vertical Axis Wind Turbine in the Spanwise Direction显示文摘The aerodynamic forces and vortex characteristics of an H-type Vertical Axis Wind Turbine(VAWT)become complicated because of dynamic stall,particularly in the three-dimensional impact on the blade spanwise direction.This study focused on the evaluation of the aerodynamic performance and vortex characteristics of an H-type VAWT in the spanwise direction by numerical simulations and wind tunnel experiments.Pressure acting on the blade surface was obtained from multiport pressure measurement devices by wind tunnel.Meanwhile,the vortex field around different blade sections was investigated through numerical simulations.The stall behavior was analysed by comparing the results of numerical simulations and experiments.As a result,the tangential force of single blade was mainly contributed at the chordwise position of x/c≤0.4 c and the power of single blade was mainly contributed at the azimuthal angle range of 60°≤θ≤150°in the blade section position region of 0≤z/(H/2)≤0.7.At the section position of z/(H/2)=0.5,the initial flow separation was found at the suction side and progressed forward to the leading edge.With the increase of the tip speed ratios,the decreasing position of the averaged local power coefficient of each section was closer to the middle section of z/(H/2)=0,and the attenuation speed became faster.The power coefficient reductions at the blade section position of z/(H/2)=0.9 were 38.29%,46.78%and 56.42%when the tip speed ratios were 1.38,2.19 and 2.58,respectively.The results of this study provided a better understanding of the development of the performance characteristics and vortex characteristics of H-type VAWT. | ZHANG Yanfeng LI Qing’an ZHU Xinyu SONG Xiaowen CAI Chang GUO Zhiping | 2021 | Journal of Thermal Science2021，30，3： | 2 |
| 5 | Study on liquids diffusion into and relevant corrosion behaviour of glass fibre reinforced polymer used in high voltage composite insulator显示文摘Long-term liquids diffusion tests were performed on glass fibre reinforced polymer(GFRP)used in high voltage composite insulator.The plate-shaped GFRP specimens were immersed in three types of liquids,which high voltage composite insulator would encounter in practice,including deionised water,NaCl solution and nitric acid solution for a period of 4000 h.Chemical reaction and physical dissolution complicated the diffusion processes,which could be divided into three types based on the features of diffusion curves.Fourier transform infrared spectroscopy,scanning electron microscopy and optical interferometry were employed to investigate the chemical property,two-dimensional(2D)and 3D surface morphologies of GFRP.The results revealed that the surface layer of GFRP was destroyed to some extent depending on the type and concentration of the liquid,the maximum of profile height deviation of GFRP surface was proposed to evaluate the extent of the corrosion of GFRP,the greater the profile height deviation,the more serious the corrosion of GFRP.The present work is helpful for a better understanding of the diffusion behaviour of liquids into GFRP used in high voltage composite insulator as well as in other industry applications. | Yanfeng Gao Xidong Liang Weining Bao Chao Wu Shaohua Li Yingyan Liu Yuanji Cai | 2020 | High Voltage2020，5，1： | 2 |
| 6 | High-throughput sequencing reveals the disruption of methylation of imprinted gene in induced pluripotent stem cells显示文摘在导致的 pluripotent 干细胞(iPSCs ) 积累的反常 epigenetic 修正是否能最终影响 iPSC pluripotency,仍然保持争论。为了探查这个问题,有一样的基因背景的 iPSC 线和 proviral 集成地点,被建立,并且每根 iPSC 线的 pluripotency 状态用 tetraploid (4N ) 被描绘互补试金。随后,基因表示和 “ 的全球 epigenetic 修正; 4N-ON ”并且相应 “ 4N-OFF ”iPSC 线通过深定序 mRNA 表示,小 RNA 侧面, histone 修正(H3K27me3, H3K4me3,和 H3K4me2 ) ,和 DNA methylation 的分析被比较。我们发现了印的基因的那 methylation, Zrsr1,一致地与减少的 pluripotency 在 iPSC 线被破坏。而且,破坏 methylation 不能被改进文化条件或 iPSCs 的 subcloning 救。而且,在 iPSCs 的 Zrsr1 和 pluripotency 状态的 hypomethylation 之间的关系进一步在线从另外的 reprogramming 系统导出的独立 iPSC 被验证。 | Gang Chang Shuai Gao Xinfeng Hou Zijian Xu Yanfeng Liu Lan Kang Yu Tao Wenqiang Liu Bo Huang Xiaochen Kou Jiayu Chen Lei An Kai Miao Keqian Di Zhilong Wang Kun Tan Tao Cheng Tao Cai Shaorong Gao Jianhui Tian | 2014 | Cell Research2014，24，3： | 2 |
| 7 | The design of HEPS global timing system显示文摘Purpose The high energy photon source(HEPS)is a 4th generation synchrotron light source under construction by the institute of high energy physics.The accelerator complex consists of a 500-MeV Linac,a full-energy synchrotron booster,a 6-GeV synchrotron storage ring(SR),and three e-beam transport lines for injection and extraction among accelerators.A global timing system(GTS)covers the timing needs for all accelerator,beamline,and experiment systems.The GTS is designed to coordinate the injection processes and various measurements and protections.Most systems require that the RMS jitter of the GTS signal is less than 30 ps,while the trigger jitters for the electron gun and SR injection and extraction kickers are less than 10 ps.Method The HEPS GTS is an event-based timing system based on MicroTCA.4 hardware architecture.The MicroTCA.4300 series products from the micro-research Finland Oy are implemented in the HEPS GTS system.Results and conclusions The RMS jitter,integrated from 1 Hz to 10 MHz,of the 166.6 MHz event clock is 5.489 ps.The RMS jitter of TTL outputs is less than 30 ps.This paper reports the design of the HEPS GTS,which satisfies all of the HEPS physics requirements for timing with preliminary test results shown. | Fang Liu Ge Lei Zhe Duan Cai Meng Chenyan Lu Yanhua Shao Xinpeng Ma Nan Gan Yuemei Peng Jianshe Cao Chungming Chu Yanfeng Sui Jingyi Li IHEP | 2021 | Radiation Detection Technology and Methods2021，5，3： | 1 |
| 8 | COVID-19 in the immunocompromised population:data from renal allograft recipients throughout full cycle of the outbreak in Hubei province,China显示文摘Coronavirus disease 2019(COVID-19)is an infectious disease caused by a newly discovered coronavirus and has rapidly spread to most of the world and resulted in a global pandemic.However,there is a paucity of information available to characterize the immunodeficient population in the COVID-19 pandemic,especially information that focuses on patients after renal transplantation as the typical representative of this population. | Weijie Zhang Fei Han Xiongfei Wu Zhendi Wang Yanfeng Wang Xiaojun Guo Song Chen Tao Qiu Heng Li Yafang Tu Zibiao Zhong Jiannan He Bin Liu Hui Zhang Zhitao Cai Long Zhang Xia Lu Lan Zhu Dong Chen Jiangqiao Zhou Qiquan Sun Zhishui Chen | 2022 | Chinese Medical Journal2022，，2： | 1 |
| 9 | Single-dose AAV-based vaccine induces a high level of neutralizing antibodies against SARS-CoV-2 in rhesus macaques显示文摘Dear Editor,Coronavirus disease 2019(COVID-19)is a highly infectious respiratory disease that continues to pose a serious global public health emergency.The disease shows a high infection rate,long incubation period,and rapidly emerging variants,which have led to its rapid spread worldwide(Krammer 2020).Many vaccines have been developed for the control of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),the virus responsible for COVID-19,including vaccines based on messenger RNA(mRNA)(Polack et al.2020),viral vectors(Zhu et al.2020),recombinant proteins(Yang et al.2020),and inactivated SARS-CoV-2(Zhang et al.2021). | Dali Tong Mei Zhang Yunru Yang Han Xia Haiyang Tong Huajun Zhang Weihong Zeng Muziying Liu Yan Wu Huan Ma Xue Hu Weiyong Liu Yuan Cai Yanfeng Yao Yichuan Yao Kunpeng Liu Shifang Shan Yajuan Li Ge Gao Weiwei Guo Yun Peng Shaohong Chen Juhong Rao Jiaxuan Zhao Juan Min Qingjun Zhu Yanmin Zheng Lianxin Liu Chao Shan Kai Zhong Zilong Qiu Tengchuan Jin Sandra Chiu Zhiming Yuan Tian Xue | 2023 | Protein & Cell2023，14，1： | 0 |
| 10 | Synthesis of C-Glucosides from Grignard Reagents Prepared by Activated Magnesium显示文摘l-α-biaomo-2,3,4,6-tetra-O-acetyl-D-giucopyranose reacts with Grignard eagents prepared frorn the acnvated magnesium under very mild condition to ellord C- glucosides in a very high yield compared with Grignard Reagent prepared from usual method.β-anomer predominates in the reaction, mixture The configuration of anomers was assigned by 13C NMR spectra. | Qiu Dongxu, Wang Yanfeng, Cai Mengshen (Ccllege of Pharmacy, Beijing Medical Ubiversity, Beijing) | 1989 | Chemical Research in Chinese Universities1989，5，2： | 0 |
| 11 | Providing free treatment for severe mental disorders in China显示文摘Following the SARS outbreak in 2003 the Chinese government substantially strengthened its public health infrastructure.One of the new programs was the‘Central Government Support for the Local Management and Treatment of Severe Mental Illnesses Project’.Initially funded in December 2004 with 6.86 million Renminbi(829,000 in 2004 US$),the ongoing project has subsequently been referred to as the‘686 Project’.The aims of the project include establishing an effective system to control and prevent violent behaviors by individuals with severe mental disorder,increasing careseeking by persons with severe mental illnesses | Yi ZHU Weibo ZHANG Yanfeng WANG Jun CAI | 2014 | 上海精神医学2014，26，2： | 0 |
| 12 | Ferroelectricity in hBN intercalated double-layer graphene显示文摘Van der Waals(vdW)assembly of two-dimensional materials has long been recognized as a powerful tool for creating unique systems with properties that cannot be found in natural compounds[Nature 499,419(2013)].However,among the variety of vdW heterostructures and their various properties,only a few have revealed metallic and ferroelectric behaviour signatures[Sci.Adv.5,eaax5080(2019);Nature 560,336(2018)].Here we show ferroelectric semimetal made of double-gated double-layer graphene separated by an atomically thin crystal of hexagonal boron nitride.The structure demonstrates high room temperature mobility of the order of 10 m2·V^(−1)·s^(−1) and exhibits ambipolar switching in response to the external electric field.The observed hysteresis is reversible and persists above room temperature.Our fabrication method expands the family of ferroelectric vdW compounds and offers a promising route for developing novel phase-changing devices.A possible microscopic model of ferroelectricity is discussed. | Yibo Wang Siqi Jiang Jingkuan Xiao Xiaofan Cai Di Zhang Ping Wang Guodong Ma Yaqing Han Jiabei Huang Kenji Watanabe Takashi Taniguchi Yanfeng Guo Lei Wang Alexander S.Mayorov Geliang Yu | 2022 | Frontiers of physics2022，17，4： | 0 |
| 13 | High drug loading hydrophobic cross-linked dextran microspheres as novel drug delivery systems for the treatment of osteoarthritis显示文摘Drug delivery via intra-articular(IA)injection has proved to be effective in osteoarthritis(OA)therapy,limited by the drug efficiency and short retention time of the drug delivery systems(DDSs).Herein,a series of modified cross-linked dextran(Sephadex,S0)was fabricated by respectively grafting with linear alkyl chains,branched alkyl chains or aromatic chain,and acted as DDSs after ibuprofen(Ibu)loading for OA therapy.This DDSs expressed sustained drug release,excellent anti-inflammatory and chondroprotective effects both in IL-1βinduced chondrocytes and OA joints.Specifically,the introduction of a longer hydrophobic chain,particularly an aromatic chain,distinctly improved the hydrophobicity of S0,increased Ibu loading efficiency,and further led to significantly improving OA therapeutic effects.Therefore,hydrophobic microspheres with greatly improved drug loading ratio and prolonged degradation rates show great potential to act as DDSs for OA therapy. | Zhimin Li Xianjing Feng Shixing Luo Yanfeng Ding Zhi Zhang Yifeng Shang Doudou Lei Jinhong Cai Jinmin Zhao Li Zheng Ming Gao | 2023 | Asian Journal of Pharmaceutical Sciences2023，18，4： | 0 |
| 14 | Performance of hydrogenated diamond field-effect transistors on single and polycrystalline diamond显示文摘In this work,we investigate the influence of defect concentration of the diamond substrates on the performance of hydrogen-terminated diamond field-effect transistors by Raman spectra,pulsed I–V characteristics analysis,and radio frequency performances measurements.It is found that a sample with higher defect concentration shows larger drain-lag effect and lower large-signal output power density.Defects in the diamond act as traps in the carrier transport and have a considerable influence on the large-signal output power density of diamond field-effect transistors.This work should be helpful for further performance improvement of the microwave power diamond devices. | Rui Zhou Cui Yu Chuangjie Zhou Jianchao Guo Zezhao He Yanfeng Wang Feng Qiu Hongxing Wang Shujun Cai Zhihong Feng | 2020 | Journal of Semiconductors2020，41，12： | 0 |
| 15 | Lynch syndrome pre-screening and comprehensive characterization in a multi-center large cohort of Chinese patients with colorectal cancer显示文摘Objective:Lynch syndrome(LS)pre-screening methods remain under-investigated in colorectal cancers(CRCs)in Asia.Here,we aimed to systematically investigate LS pre-screening and comprehensively characterize LS CRCs.Methods:Microsatellite instability(MSI)and germline variants of DNA mismatch repair(MMR)genes were examined in 406 deficient MMR(dMMR)and 250 proficient MMR CRCs.The genetic differences between LS and sporadic CRCs were studied with whole exome sequencing analysis.Results:The incidence of dMMR in Chinese patients with CRCs was 13.8%.Consistency analysis between MMR immunohistochemistry(IHC)and MSI testing showed the kappa value was 0.758.With next-generation sequencing(NGS),germline variants were detected in 154 CRCs.Finally,88 patients with CRC were identified as having LS by Sanger sequencing.Among them,we discovered 21 previously unreported pathogenic germline variants of MMR genes.Chinese patients with LS,compared with sporadic CRCs,tended to be early-onset,right-sided,early-stage and mucinous.Overall,the performance of MMR IHC and MSI testing for LS pre-screening was comparable:the area under the ROC curve for dMMR,MSI-H,and MSI-H/L was 0.725,0.750,and 0.745,respectively.dMMR_MSI-H LS and sporadic CRCs showed substantial differences in somatic genetic characteristics,including different variant frequencies of APC,CREBBP,and KRAS,as well as different enriched pathways of VEGF,Notch,TGFβR,mTOR,ErbB,and Rac protein signal transduction.Conclusions:MMR IHC and MSI testing were effective methods for LS pre-screening.The revealed clinical and somatic genetic characteristics in LS CRCs may have the potential to improve the performance of LS pre-screening in combination with dMMR/MSI. | Yan Li Lihong Fan Jianming Zheng Xiu Nie Yu Sun Qin Feng Shenyi Lian Wenqi Bai Weijing Cai Yanan Yang Bo Su Yanfeng Xi Dongmei Lin | 2022 | Cancer Biology & Medicine2022，19，8： | 0 |
| 16 | Effects of liquids immersion and drying on the surface properties of HTV silicone rubber:characterisation by contact angle and surface physical morphology显示文摘High-temperature vulcanised(HTV)silicone rubber composite insulator has been widely used in extra-high and ultra-high transmission lines due to its excellent electrical and mechanical performance.In practice use,liquids may encounter the composite insulator intermittently and can lead to the degradation and deterioration of silicone rubber.In the present research,the effects of liquids immersion and subsequent drying on the surface properties of HTV silicone rubber were investigated by means of the contact angle measurement and surface physical morphology measurement which was further analysed in terms of the discrete wavelet transform method,multiresolution signal decomposition algorithm,and three-dimensional fractal dimension calculation.Based on the experimental results,the mechanism of the loss and recovery of the hydrophobicity of HTV silicone rubber surface during the liquids immersion and subsequent drying processes were further explained by taking into consideration the embedded water molecules(and/or hydrated ions)on the HTV silicone rubber surface and the synergy of the increase in roughness/fractal dimension and low molecular weight siloxanes diffusion.This study is helpful for better understanding of the change of surface properties of HTV silicone rubber caused by environmental and electrical stresses. | Yanfeng Gao Xidong Liang Weining Bao Shaohua Li Chao Wu Yingyan Liu Yuanji Cai | 2019 | High Voltage2019，4，1： | 0 |
| 17 | Halogen-doped phosphorescent carbon dots for grayscale patterning显示文摘Flexible organic materials that exhibit dynamic ultralong room temperature phosphorescence(DURTP)via photoactivation have attracted increasing research interest for their fascinating functions of reversibly writing-reading-erasing graphic information in the form of a long afterglow.However,due to the existence of a nonnegligible activation threshold for the initial exposure dose,the display mode of these materials has thus far been limited to binary patterns.By resorting to halogen element doping of carbon dots(CDs)to enhance intersystem crossing and reduce the activation threshold,we were able to produce,for the first time,a transparent,flexible,and fully programmable DURTP composite film with a reliable grayscale display capacity.Examples of promising applications in UV photography and highly confidential steganography were constructed,partially demonstrating the broad future applications of this material as a programmable platform with a high optical information density. | Yanfeng Liu Mahmoud Al-salihi Yong Guo Roman Ziniuk Songtao Cai Luwei Wang Yuan Li Zhigang Yang Dengfeng Peng Kai Xi Zhongfu An Xudong Jia Liwei Liu Wei Yan Junle Qu | 2022 | Light(Science & Applications)2022，11，7： | 0 |
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