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| 1 | Zircon U-Pb SHRIMP ages of the Taiping (calc-alkaline)-Huangshan (alkaline) composite intrusion:Constraints on Mesozoic lithospheric thinning of the southeastern Yangtze Craton,China显示文摘The Taiping-Huangshan composite intrusion is a unique complex with characteristics changing from calc-alkaline (Taiping intrusion) to alkaline (Huangshan intrusion). Huangshan intrusion samples show a spectacular tetrad effect in their REE distribution patterns as well as non-CHARAC (charge-and radius-controlled) trace element behavior, indicating a highly evolved late-stage magma component. This composite intrusion provides a rare opportunity to investigate the variance of tectonic setting and lithospheric thinning of the southeastern Yangtze Craton in late Mesozoic era. Zircon SHRIMP U-Pb analyses yield an emplacement age of 140.6±1.2 Ma for the Taiping intrusion, and ages of 127.7±1.3, 125.7±1.4, 125.1±1.5, and 125.2±5.5 Ma for four samples from the Huangshan intrusion respectively. The ages for four different phases of the Huangshan intrusion agree within their small analytical errors, indicating that the emplacement was in a short time. The Taiping and Huangshan intrusions are intimately associated, but there is about 15 Ma interval between their intrusion, and the magma characters change from calc-alkaline to alkaline without transition. This probably corresponds to lithospheric thinning of the southeastern Yangtze Craton. This event possibly happened from about 141 Ma (the emplacement age of the Taiping intrusion), to 128 Ma (start of emplacement of the Huangshan intrusion). The thinning mechanism is dominantly delamination. | XUE HuaiMin WANG YingGeng MA Fang WANG Cheng WAN DeEn ZUO YanLong | 2009 | Science China Earth Sciences2009，52，11： | 28 |
| 2 | Isatin decreases Bax protein expression in the substantia nigra of a mouse model of Parkinson's disease显示文摘The present study observed the action of 1H-indole-2, 3-dione (isatin) on Bax protein expression in the substantia nigra of a Parkinson's disease animal model. Parkinson's disease-like behaviors were induced in C57BL/6J mice treated with 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP). Bax protein expression was significantly reduced in isatin (100, 200 mg/kg)-pretreated mice. Results demonstrate that isatin plays a neuroprotective role in mice treated with MPTP by down-regulating Bax protein expression. | Jiguo Zhang Fang Zhang Yanlong Qiu Wang Yue | 2011 | Neural Regeneration Research2011，6，26： | 3 |
| 3 | Organic-inorganic hybrid hole transport layers with SnS doping boost the performance of perovskite solar cells显示文摘Perovskite solar cells(PSCs) have demonstrated excellent photovoltaic performance which currently rival the long-standing silicon solar cells’ efficiency. However, the relatively poor device operational stability of PSCs still limits their future commercialization. Binary sulfide is a category of materials with promising optoelectrical properties, which shows the potential to improve both the efficiency and stability of PSCs.Here we demonstrate that the inorganic tin monosulfide(Sn S) can be an efficient dopant in 2,2’,7,7’-tet rakis(N,N-di-p-methoxy-phenylamine)-9,9’-spirobifluorene(spiro-OMe TAD) to form a composite hole transport layer(HTL) for PSCs. Sn S nanoparticles(NPs) synthesized through a simple chemical precipitation method exhibit good crystallization and suitable band matching with the perovskites. The introduction of Sn S NPs in Spiro-OMTAD HTLs enhanced charge extraction, reduced trap state density, and shallowed trap state energy level of the devices based on the composite HTLs. Therefore, the resulting solar cells employing Sn S-doped spiro-OMe TAD HTLs delivered an improved stabilized power output efficiency of 21.75% as well as enhanced long-term stability and operational stability. Our results provide a simple method to modify the conventional spiro-OMe TAD and obtain PSCs with both high efficiency and good stability. | Xiaolu Zheng Haibing Wang Feihong Ye Cong Chen Weijun Ke Wenjing Zhang Chuanxin He Yanlong Tai Guojia Fang | 2022 | Journal of Energy Chemistry2022，31，5： | 1 |
| 4 | Characterization of a Hemolysin Gene ytjA from Bacillus subtilis显示文摘 | Jie Liu Chunhong Fang Yanlong Jiang Ruoyu Yan | 2009 | Current Microbiology2009，，6： | 1 |
| 5 | Formation and growth mechanisms of ultrafine particles in sludge-incineration flue gas显示文摘Atmospheric particulate matter with diameter<2.5μm now makes up much of the air pollution in China,but it is the ultrafine particles(UFPs)with diameter<90 nm that are of particular interest.This is because UFPs are strongly linked with human health for two reasons:they contain a variety of hazardous substances and they can deeply penetrate human respiratory systems.Therefore,scanning electron microscopy combined with X-ray dispersive energy spectrometry was used to characterize the morphology and surface texture,as well as the elemental composition of 60 UFPs.The UFPs was generated in a sewage sludge-incineration power plant in Zhejiang Province.This was done to determine the microstructure of the ultrafine particles and to follow the evolution of particle surface elemental composition with increasing particle size.Then,a comparison of the characteristic time for nucleation,condensation and coagulation was done to estimate the dominant mechanism.The results show that the UFPs have generally irregular shapes(cotton-like,irregular balls,sheets,etc.)and that they usually aggregate to form a mass.With increase in the size of a UFP,the mass fraction of the elements presents clearly changed:Na,K and Fe gradually decreased;while Ca,Si and Al,as well as the heavy metals Cu,Zn and Ni increased.Characteristic time estimation is a convenient and effective tool for identifying the predominant mechanisms during combustion.In this study,calculations of characteristic time were used to reveal a mechanism of vaporization,nucleation,condensation and coagulation,which drives the formation and growth of ultrafine particles. | Yanlong Li Jiaqi Man Zhengquan Fang Yunbin Zhao Feng Wang Rundong Li | 2019 | Waste Disposal and Sustainable Energy2019，1，2： | 1 |
| 6 | Comparison of two methods for evaluating lower urinary tract symptoms in cervical cancer patients following radical hysterectomy显示文摘Objective:To compare the degree of agreement and consistency of urodynamic studies(UDS)with low urinary tract symptoms(LUTS)questionnaires for evaluating LUTS in cervical cancer patients following radical hysterectomy(RH)and pelvic lymphadenectomy.Methods:From January 2012 to March 2015,204 cervical cancer patients who underwent RH in 13 hospitals were evaluated using the Incontinence Questionnaire-Female Lower Urinary Tract Symptoms(ICIQ-FLUTS)and the Overactive Bladder Symptom Score(OABSS).Urodynamic tests were also performed on these patients during the same period.Results:Study participants’age ranged from 23 to 75 years,with a mean(standard deviation)of 48.0±9.3 years.Using questionnaires,the prevalence of patients with LUTS symptoms,including storage symptoms,voiding symptoms,stress urinary incontinence(SUI)and overactive bladder(OAB)was 86.3%,77.0%,62.7%,52.9%and 14.7%,respectively.For UDS,the corresponding prevalence was 89.7%,70.1%,66.7%,46.6%and 13.2%,respectively.The diagnostic concordance of questionnaires and UDS for storage symptoms,voiding symptoms,SUI and OAB was 79.9%,66.7%,66.7%,57.4%and 79.9%,respectively.For voiding symptoms,the correlation coefficient was 0.272,which was higher than that of storage symptoms,SUI and OAB. | Fang An Sha Wang Zhiqi Wang Lingying Wu Qiubo Lv Aiming Lv Hongwu Wen Jinsong Han Yumei Wu Yunong Gao Qing Liu Sumei Wang Hongxia Li Luwen Wang Yanlong Wang Ruifang Wu Huan Li Xiuli Sun | 2021 | Gynecology and Obstetrics Clinical Medicine2021，1，2： | 0 |
| 7 | Sc(OTf)_(3)-catalyzed synthesis of polysubstituted furans from acylacetonitriles and renewable acetol显示文摘A[3+2]cyclization reaction of acylacetonitriles and hydroxyacetone was developed by using Sc(OTf)_(3)as a catalyst to synthesize some furan derivatives.Bifunctional C2-based acetals,such asα-bromoacetaldehyde acetal,1,4-dithiane-2,5-diol and glycolaldehyde diethyl acetal,also reacted readily as alternative counterpart reagents to acylacetonitriles.The established reactions can be used to synthesize a well-known fungicide,fenfuram.Antifungal activity investigation against four common plant funguses indicated that some of the obtained furan products furnish general and high biological activities. | Wenbo Huang Fang Liu Kaimei Wang Alexander Sidorenko Maxim Bei Zhigang Zhang Wei Fang Minghao Li Yanlong Gu Shaoyong Ke | 2022 | Green Synthesis and Catalysis2022，3，4： | 0 |
| 8 | Mapping QTL affecting the vertical distribution and seed set of soybean [Glycine max(L.) Merr.] pods显示文摘Number of pods per plant and number of seeds per pod are quantitative,multigenic traits and important components of yield in soybean[Glycine max(L.)Merr.].Pods are distributed unevenly in the upper,middle,and lower segments of the plant and this distribution is affected by sowing date(SD).A population of four-way recombinant inbred lines(FW-RIL),containing 160 F2:8 individuals,was generated from the cross(Kenfeng 14×Kenfeng 15)×(Heinong 48×Kenfeng 19).A linkage map consisting of 275 simple sequence repeat(SSR)markers was used to map quantitative trait loci(QTL)associated with the production of one,two,three,and four seeds per pod in the upper,middle,and lower segments of plants at two SDs,totaling 12 measurements per SD.A wide range of variation in the twelve characteristics was observed among the four parental lines and the FW-RIL population at the two SDs.The effect of SD2(May 17,2016)on pod number was stronger than that of SD1(May 7,2016)because the heritability of each trait in the SD1 experiment was generally greater than that of SD2.The study identified 76 QTL controlling pod number,with the phenotypic variation explained by each QTL ranging from 1.86%to 13.71%.The numbers of QTL controlling one,two,three,and four seeds per pod were 28,23,23,and 23,respectively.There were 30,28,and 28 QTL controlling the pod number in the upper,middle,and lower segments of the plant,respectively.Forty-five QTL were identified at SD1 and 38 QTL were identified at SD2.Seventeen QTL were associated with pod-number traits.The QTL qPNA1–3 was associated with the number of pods containing one seed in the middle segment of the plant at both SDs.Sixty-three QTL were published QTL(common areas existed when integrating on a map GmComposite2003 of Wm82 based on left and right markers).and 13 QTL related to pod number were newly discovered.These results provide a reference for breeders to improve soybean yield by combining advantageous alleles for these QTL.Future studies may reveal candidate genes for these QTL and identify causal alleles for markerassisted selection. | Shiping Liu Hong Xue Kaixin Zhang Ping Wang Daiqun Su Wenbin Li Shichao Xu Jianan Zhang Zhongying Qi Yanlong Fang Xiyu Li Yue Wang Xiaocui Tian Jie Song Jiajing Wang Chang Yang Sitong Jiang Wen-Xia Li Hailong Ning | 2019 | The Crop Journal2019，7，5： | 0 |
| 9 | Experimental study on sand production and coupling response of silty hydrate reservoir with different contents of fine clay during depressurization显示文摘To further understand the characteristics of clay and sand production(hereafter collectively referred to as sand production)and to provide optimization designs of sand control schemes are critical for gas production from clayey silt natural gas hydrate reservoirs in the South China Sea.Thus,gas-water-sand production behavoirs and coupling reservoir subsidence characteristics before,during,and after hydrate dissociation of the clayey silt hydrate reservoirs with different clay contents(5%,10%,15%,20%,25%,and 30%)have been studied through a self-developed experimental system.The results show that with the increase of clay content,the total mass of sand production first increases and then decreases,and it reaches maximum when the clayey content is 20%.The sand production is the lowest before hydrate dissociation and increases significantly during hydrate dissociation,which mainly occurs in the high-speed gas and water production stage at the beginning of hydrate dissociation.After hydrate dissociation,the sand production decreases significantly.During the whole depressurization process,the clay and free sand particles generally move to the sand outlet due to the fluid driving force and overlying stress extrusion.However,for conditions of high clay contents,those particles fail to pass through the sand control screen and gradually accumulate and block the screen by forming a mud cake,which greatly reduce the permeability of the screen and limite sand production as well as gas and water production.Our research lays a foundation for sand production prediction and sand control scheme selection during gas recovery from clayey silty hydrate reservoirs that greatly need to consider a balance between sand control and gas productivity. | Xiangyu Fang Dianheng Yang Fulong Ning Linjie Wang Zhichao Liu Yanjiang Yu Wenwei Xie Hongfeng Lu Yanlong Li Meng Xu | 2023 | Petroleum2023，9，1： | 0 |
| 10 | Rationally optimized generation of integrated Escherichia coli with stable and high yield lycopene biosynthesis from heterologous mevalonate(MVA)and lycopene expression pathways显示文摘The stability and high productivity of heterogeneous terpenoid production in Escherichia coli expression system is one of the most key issues for its large scale industrialization.In the current study on taking lycopene biosynthesis as an example,an integrated Escherichia coli system has been generated successfully,which resulted into stable and high lycopene production.In this process,two modules of mevalonate(MVA)pathway and one module of lycopene expression pathway were completely integrated in the chromosome.Firstly,the copy number and integrated position of three modules of heterologous pathways were rationally optimized.Later,a strain DH416 equipped with heterogeneous expression pathways through chromosomal integration was efficiently derived from parental strain DH411.The evolving DH416 strain efficiently produced the lycopene level of 1.22 g/L(49.9 mg/g DCW)in a 5 L fermenter with mean productivity of 61.0 mg/L/h.Additionally,the integrated strain showed more genetic stability than the plasmid systems after successive 21st passage. | Muhammad Hammad Hussain Qi Hong Waqas Qamar Zaman Ali Mohsin Yanlong Wei Ning Zhang Hongqing Fang Zejian Wang Haifeng Hang Yingping Zhuang Meijin Guo | 2021 | Synthetic and Systems Biotechnology2021，6，2： | 0 |
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