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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | A Chromosome-Scale Genome Assembly of Paper Mulberry(Bmussonetia papyrifera)Provides New Insights into Its Forage and Papermaking Usage显示文摘Paper mulberry(Broussonetia papyrifera)is a well-known woody tree historically used for Cai Lun papermaking,one of the four great inventions of ancient China.More recently,Paper mulberry has also been used as forage to address the shortage of feedstuff because of its digestible crude fiber and high protein contents.In this study,we obtained a chromosome-scale genome assembly for Paper mulberry using integrated approaches,including Illumina and PacBio sequencing platform as well as Hi-C,optical,and genetic maps.The assembled Paper mulberry genome consists of 386.83 Mb,which is close to the estimated size,and 99.25%(383.93 Mb)of the assembly was assigned to 13 pseudochromosomes.Comparative genomic analysis revealed the expansion and contraction in the flavonoid and lignin biosynthetic gene families,respectively,accounting for the enhanced flavonoid and decreased lignin biosynthesis in Paper mulberry.Moreover,the increased ratio of syringyl-lignin to guaiacyl-lignin in Paper mulberry underscores its suitability for use in medicine,forage,papermaking,and barkcloth making.We also identified the rootassociated microbiota of Paper mulberry and found that Pseudomonas and Rhizobia were enriched in its roots and may provide the source of nitrogen for its stems and leaves via symbiotic nitrogen fixation.Collectively,these results suggest that Paper mulberry might have undergone adaptive evolution and recruited nitrogen-fixing microbes to promote growth by enhancing flavonoid production and altering lignin monomer composition.Our study provides significant insights into genetic basis of the usefulness of Paper mulberry in papermaking and barkcloth making,and as forage.These insights will facilitate further domestication and selection as well as industrial utilization of Paper mulberry worldwide. | Xianjun Peng Hui Liu Peilin Chen Feng Tang Yanmin Hu Fenfen Wang Zhi Pi Meiling Zhao Naizhi Chen Hui Chen Xiaokang Zhang Xueqing Yan Min Liu Xiaojun Fu Guofeng Zhao Pu Yao Lili Wang He Dai Xuming Li Wei Xiong Wencai Xu Hongkun Zheng Haiyan Yu Shihua Shen | 2019 | Molecular Plant2019，12，5： | 18 |
| 3 | The RNA-binding protein QKI5 regulates primary miR-124-1 processing via a distal RNA motif during erythropoiesis显示文摘 | Fang Wang Wei Song Hongmei Zhao Yanni Ma Yuxia Li Di Zhai Jingnan Pi Yanmin Si Jiayue Xu Lei Dong Rui Su Mengmeng Zhang Yong Zhu Xiaoxia Ren Fei Miao Wenjie Liu Feng Li Junwu Zhang Aibin He Ge Shan Jingyi Hui Linfang Wang Jia Yu | 2017 | Cell Research2017，27，3： | 7 |
| 4 | Effects of environmental contaminants on fertility and reproductive health显示文摘Recent research indicates that the human infertility rate is increasing. Although various reasons have been hypothesized for the growing infertility rate, environmental contaminants are potentially important causal agents associated with this change.Chemical contaminants are widespread throughout our environment and human exposure is virtually unavoidable. The overall contribution of environmental exposure to infertility is unknown, but studies involving occupational exposure, together with results from animal experiments, suggest that environmental contaminants may adversely affect fertility. We reviewed the adverse effects of environmental exposure on fertility and related reproductive outcomes. Environmental contaminants covered in this review include heavy metals, organic solvents, pesticides and endocrine disrupting chemicals. It is hoped that this review will highlight the need for further research in this area. | Yanmin Ma Xin He Keyan Qi Tong Wang Yongchao Qi Lele Cui Fengbang Wang Maoyong Song | 2019 | Journal of Environmental Sciences2019，31，3： | 6 |
| 5 | EGFR/cell membrane chromatography-online-high performance liquid chromatography/mass spectrometry method for screening EGFR antagonists from Radix Angelicae Pubescentis显示文摘The intracellular kinase domains of the epidermal growth factor receptor(EGFR) in some tumor cells are significant targets for drug discovery.We have developed a new EGFR cell membrane chromatography(EGFR/CMC)-online-high performance liquid chromatography/mass spectrometry(HPLC/MS) method for screening anti-EGFR antagonists from medicinal herbs such as Radix Angelicae Pubescentis.In this study,the HEK293 EGFR cells with high expression of EGFR were used to prepare cell membrane stationary phase(CMSP) in the EGFR/CMC model.The retention fractions on the EGFR/CMC model were directly analyzed by combining a 10 port columns switcher with a HPLC/MS system online.As a result,osthole from Radix Angelicae Pubescentis was found to be the active component acting on EGFR like dasatinib as the control drug.There was a good relationship between their inhibiting effects on EGFR secretion and HEK293 EGFR cell growth in vitro.This new EGFR/CMC-online-HPLC/MS method can be applied for screening anti-EGFR antagonists from TCMs,for instance,Radix Angelicae Pubescentis.It will be a useful method for drug discovery with natural medicinal herbs as a leading compound resource. | SiCen Wang Meng Sun YanMin Zhang Jie Zhang LangChong He | 2010 | Science China Chemistry2010，53，11： | 5 |
| 6 | High-performance quasi-2D perovskite light-emitting diodes: from materials to devices显示文摘Quasi-two-dimensional(quasi-2D)perovskites have attracted extraordinary attention due to their superior semiconducting properties and have emerged as one of the most promising materials for next-generation lightemitting diodes(LEDs).The outstanding optical properties originate from their structural characteristics.In particular,the inherent quantum-well structure endows them with a large exciton binding energy due to the strong dielectricand quantum-confinement effects;the corresponding energy transfer among different n-value species thus results in high photoluminescence quantum yields(PLQYs),particularly at low excitation intensities.The review herein presents an overview of the inherent properties of quasi-2D perovskite materials,the corresponding energy transfer and spectral tunability methodologies for thin films,as well as their application in high-performance LEDs.We then summarize the challenges and potential research directions towards developing high-performance and stable quasi-2D PeLEDs.The review thus provides a systematic and timely summary for the community to deepen the understanding of quasi-2D perovskite materials and resulting LED devices. | Li Zhang Changjiu Sun Tingwei He Yuanzhi Jiang Junli Wei Yanmin Huang Mingjian Yuan | 2021 | Light(Science & Applications)2021，10，4： | 5 |
| 7 | Application of regional citrate anticoagulation in patients at high risk of bleeding during intermittent hemodialysis:a prospective multicenter randomized controlled trial显示文摘Objective:Safe and effective anticoagulation is essential for hemodialysis patients who are at high risk of bleeding.The purpose of this trial is to evaluate the effectiveness and safety of two-stage regional citrate anticoagulation(RCA)combined with sequential anticoagulation and standard calcium-containing dialysate in intermittent hemodialysis(IHD)treatment.Methods:Patients at high risk of bleeding who underwent IHD from September 2019 to May 2021 were prospectively enrolled in 13 blood purification centers of nephrology departments,and were randomly divided into RCA group and saline flushing group.In the RCA group,0.04 g/mL sodium citrate was infused from the start of the dialysis line during blood draining and at the venous expansion chamber.The sodium citrate was stopped after 3 h of dialysis,which was changed to sequential dialysis without anticoagulant.The hazard ratios for coagulation were according to baseline.Results:A total of 159 patients and 208 sessions were enrolled,including RCA group(80 patients,110 sessions)and saline flushing group(79 patients,98 sessions).The incidence of severe coagulation events of extracorporeal circulation in the RCA group was significantly lower than that in the saline flushing group(3.64%vs.20.41%,P<0.001).The survival time of the filter pipeline in the RCA group was significantly longer than that in the saline flushing group((238.34±9.33)min vs.(221.73±34.10)min,P<0.001).The urea clearance index(Kt/V)in the RCA group was similar to that in the saline flushing group with no statistically significant difference(1.12±0.34 vs.1.08±0.34,P=0.41).Conclusions:Compared with saline flushing,the two-stage RCA combined with a sequential anticoagulation strategy significantly reduced extracorporeal circulation clotting events and prolonged the dialysis time without serious adverse events. | Xiaoyan TANG Dezheng CHEN Ling ZHANG Ping FU Yanxia CHEN Zhou XIAO Xiangcheng XIAO Weisheng PENG Li CHENG Yanmin ZHANG Hongbo LI Kehui LI Bizhen GOU Xin WU Qian YU Lijun JIAN Zaizhi ZHU Yu WEN Cheng LIU Hen XUE Hongyu ZHANG Xin HE Bin YAN Liping ZHONG Bin HUANG Mingying MAO | 2022 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2022，23，11： | 4 |
| 8 | Instantaneous Attributes Analysis of Seismic Signals Using Improved HHT显示文摘As the key technique of improved Hilbert-Huang transform(HHT),ensemble empirical mode decomposition(EEMD) has a good performance of eliminating mode mixing phenomenon,which has a strong impact on the observation of seismic information.However,the intrinsic mode functions(IMF) obtained from EEMD contain noises,so that it is required to find a more robust frequency estimation method to calculate the instantaneous frequency(IF) of IMF.For this reason,the improved HHT algorithm based on the damped instantaneous frequency(DIF) is proposed to overcome the shortage of EEMD.Compared with other IF estimation methods,the DIF has strong antinoise ability and high estimation accuracy.The test results of synthetic and real seismic data show that the proposed algorithm is feasible and effective for extracting seismic instantaneous attributes. | Yuqing Wang Zhenming Peng Yanmin He | 2015 | Journal of Earth Science2015，26，4： | 2 |
| 9 | Seismic Attribute Analysis with Saliency Detection in Fractional Fourier Transform Domain显示文摘Most image saliency detection models are dependent on prior knowledge and demand high computational cost. However, spectral residual(SR) and phase spectrum of the Fourier transform(PFT) models are simple and fast saliency detection approaches based on two-dimensional Fourier transform without the prior knowledge. For seismic data, the geological structure of the underground rock formation changes more obviously in the time direction. Therefore, one-dimensional Fourier transform is more suitable for seismic saliency detection. Fractional Fourier transform(FrFT) is an improved algorithm for Fourier transform, therefore we propose the seismic SR and PFT models in one-dimensional FrF T domain to obtain more detailed saliency maps. These two models use the amplitude and phase information in FrFT domain to construct the corresponding saliency maps in spatial domain. By means of these two models, several saliency maps at different fractional orders can be obtained for seismic attribute analysis. These saliency maps can characterize the detailed features and highlight the object areas, which is more conducive to determine the location of reservoirs. The performance of the proposed method is assessed on both simulated and real seismic data. The results indicate that our method is effective and convenient for seismic attribute extraction with good noise immunity. | Yuqing Wang Zhenming Peng Yan Han Yanmin He | 2018 | Journal of Earth Science2018，29，6： | 2 |
| 10 | A wet adhesion inspired biomimetic pad with direction dependence and adaptability显示文摘A novel adhesive pad for a climbing robot, inspired by a stick insect's smooth pad, is proposed. The micro structure pattern and inclined fiber of a stick insect's pad are mimicked, and an adhesion force is produced based on its wet adhesion mechanism. Firstly, the wet adhesion model is discussed and the pad is designed; secondly, the adhesion characteristics, adhesion direction dependence and adaptability are analyzed; finally, the proposed pad is fabricated using a thermoplastic elastomer, which is a hydrophilic and viscoelastic material. Experimental results show that the adhesion performance of the pad is good, and normal adhesion and friction can reach to 0.65 N and 3 N. Furthermore, the adhesion of the pad is direction dependent and self-adaptive. | LI MingHe HE Bin QIN HaiYan ZHOU YanMin LU HanXiong YUE JiGuang | 2011 | Chinese Science Bulletin2011，56，18： | 2 |
| 11 | Slurry rheology in wet uhrafine grinding of industrial minerals: a review 显示文摘 | HE Mingzhao WANG Yanmin Forssberga E | 2004 | Powder Technology2004，147，1： | 1 |
| 12 | Using an Integrated Response-Function Method to Explore Agro-Climatic Suitability for Spring Soybean Growth in North China显示文摘 | Yingbin He Yanmin Yao Huajun Tang | | 0，，06： | 1 |
| 13 | Taspine Isolated from Radix et Rhizoma Leonticis Inhibits Proliferation and Migration of Endothelial Cells as well as Chicken Chorioallantoic Membrane Neovascularisation显示文摘 | Zhang Yanmin He Langchong Meng Liang | 2008 | Vasc Pharmacol2008，48，23： | 1 |
| 14 | Suppression of Tumor-induced Angiogenesis by Taspine Isolated from Radix et Rhizoma Leonticis and Its Mechanism of Action in vitro显示文摘 | Zhang Yanmin He Langchong Meng Liang | 2008 | Cancer Lett2008，262，1： | 1 |
| 15 | Taspine Isolated from Radix et Rhizoma Leonticis Inhibits Growth of Human Umbilical Vein Endothelial Cell ( HUVEC ) by Inducing Its Apoptosis 显示文摘 | Zhang Yanmin He Langchong Zhou Yali | 2008 | Phytomedicine2008，15，12： | 1 |
| 16 | International comparison on carbon trading market development and its implication显示文摘 | CHEN Liyun HE Yu MEI Yanmin | 2015 | Finance and Accounting for International Commerce2015，，10： | 1 |
| 17 | Slurry rheology in wet ultrafine grinding of industrial minerals: a review显示文摘 | Mingzhao He Yanmin Wang Eric Forssberg | 2004 | Powder Technology2004，，1： | 1 |
| 18 | Relative severity investigation in a severe load spectrum 显示文摘 | Xiaofan He Fucheng Sui Yanmin Dong | 2010 | Engineering Failure Analysis2010，17，78： | 1 |
| 19 | Adaptive Denoising by Singular Value Decomposition显示文摘 | Yanmin He Tao Gan Wufan Chen Houjun Wang | | 0，，04： | 1 |
| 20 | Successful treatment of refractory pure red cell aplasia with eltrombopag after ABO-incompatible allogeneic hematopoietic stem cell transplantation显示文摘Pure red cell aplasia(PRCA) is a well-recognized complication of ABO major mismatched allogeneic hematopoietic stem cell transplantation(allo-HSCT), with a reported incidence of 10% – 20%(Zhidong et al., 2012;Busca et al., 2018). It is clinically characterized by anemia, reticulocytopenia,and the absence of erythroblasts in a normal-appearing bone marrow biopsy(Shahan and Hildebrandt, 2015).The mechanism for PRCA has been presumed to be persistence of recipient isoagglutinins, produced by residual host B lymphocytes or plasma cells。 | Yang GAO Fei GAO Jimin SHI Huarui FU He HUANG Yanmin ZHAO | 2021 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2021，22，8： | 1 |
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