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54篇 您的检索式:作者名="Yanyan Ding"
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1Removal characteristics of microplastics by Fe-based coagulants during drinking water treatment显示文摘Microplastics have caused great concern worldwide recently due to their ubiquitous presence within the marine environment. Up to now, most attention has been paid to their sources,distributions, measurement methods, and especially their eco-toxicological effects. With microplastics being increasingly detected in freshwater, it is urgently necessary to evaluate their behaviors during coagulation and ultrafiltration(UF) processes. Herein, the removal behavior of polyethylene(PE), which is easily suspended in water and is the main component of microplastics, was investigated with commonly used Fe-based salts. Results showed that although higher removal efficiency was induced for smaller PE particles, low PE removal efficiency(below 15%) was observed using the traditional coagulation process, and was little influenced by water characteristics. In comparison to solution pH, PAM addition played a more important role in increasing the removal efficiency, especially anionic PAM at high dosage(with efficiency up to 90.9%). The main reason was ascribed to the dense floc formation and high adsorption ability because of the positively charged Fe-based flocs under neutral conditions. For ultrafiltration, although PE particles could be completely rejected,slight membrane fouling was caused owing to their large particle size. The membrane flux decreased after coagulation; however, the membrane fouling was less severe than that induced by flocs alone due to the heterogeneous nature of the cake layer caused by PE, even at high dosages of Fe-based salts. Based on the behavior exhibited during coagulation and ultrafiltration, we believe these findings will have potential application in drinking water treatment.Baiwen Ma Wenjing Xue Yanyan Ding Chengzhi Hu Huijuan Liu Jiuhui Qu 2019Journal of Environmental Sciences2019,31,4:29
2Improvement of the Surface Pressure Operator in GRAPES and Its Application in Precipitation Forecasting in South China显示文摘在这研究,我们调查了涉及在当前的全球、地区性的吸收和预言系统吸收表面压力的问题,葡萄。吸收表面压力的一个新计划被建议,包括一个新插值计划和使清醒的背景协变性。新计划考虑车站举起和模型地形学之间的差别,并且它特别处理在第一模型水平的下面在举起定位的车站。对比实验用原版和新吸收计划被进行。新插值计划和更新的背景协变性的影响被调查。我们的结果证明新插值计划利用了更多的观察并且改进了集体分析的质量。背景协变性用源于帕里什和 Derber 在 1992 建议的技术的统计被使清醒。当吸收表面压力时,实验证明更新的垂直协变性可以在空气的高水平在分析上有积极影响。如果在高水平的背景地的质量是差的,这影响可能是更重要的。一系列吸收实验被执行测试新计划的有效性。相应模拟实验作为起始的条件用两个计划的分析被进行。结果显示新计划导致在华南的海水平压力和降水的更好的预报,特别预报中等并且大雨。HUANG Yanyan XUE Jishan WAN Qilin CHEN Zitong DING Weiyu ZHANG Chengzhong 2013Advances in Atmospheric Sciences2013,30,2:10
3Effects of protein properties on ultrafiltration membrane fouling performance in water treatment显示文摘Protein-like substances always induce severe ultrafiltration(UF) membrane fouling. To systematically understand the effect of proteins, regenerated cellulose UF membrane(commonly used for protein separation) performance was investigated in the presence of bovine serum albumin(BSA) under various water conditions. Results showed that although trypsin enhanced the membrane flux via proteolysis, catalysis took a long time. Membrane fouling was alleviated at high solution p H and low water temperature owing to the strong electrostatic repulsion force among BSA molecules. Both Na^+ and Ca^(2+)could increase membrane flux. However, Ca^(2+)played a bridging role between adjacent BSA molecules,whereas membrane fouling was alleviated via a hydration repulsion force with Na+. The order of influence on membrane fouling was as follows: Ca^(2+)concentration > Na+concentration > pH > temperature > trypsin concentration. Furthermore, a polyvinylidene fluoride UF membrane experiment showed that Ca^(2+)could reduce the fouling induced by BSA. Thus, the differences in UF membrane performance will have application potential for alleviating UF membrane fouling induced by proteins during water treatment.Yanyan Ding Baiwen Ma Huijuan Liu Jiuhui Qu 2019Journal of Environmental Sciences2019,31,3:9
4Performance of halogen-free flame retardant EVA/MH/LDH composites with nano-LDHs and MH显示文摘The flammability properties of three series of Ethylene-Vinyl Acetate/Magnesium Hydroxide/Layered Double Hydroxide(EVA/MH/LDH) composites as well as the flame retardance effect between LDH and the conventional flame retardant additive MH are investigated.In addition to acting as an insulating barrier,LDH assists the dispersion of MH particles in the EVA matrix,and promotes the formation of the char residues because of its abundant interlayer hydroxyl groups.Composites containing LDH show good flame retardancy in Cone and LOI testings.This means that the combustion properties of the composites have decreased,which may lessen the fire hazard when this materials are used.DING YanYan XU Liang HU GengSheng 2011Chinese Science Bulletin2011,56,35:8
5Two congenital coronary abnormalities affecting heart function: anomalous origin of the left coronary artery from the pulmonary artery and congenital left main coronary artery atresia显示文摘Xiao Yanyan Jin Mei Han Ling Ding Wenhong Zheng Jianyong Sun Chufan Lyu Zhenyu 2014Chinese Medical Journal2014,,21:7
6Numerical simulation for erosion effects of three-phase flow containing sulfur particles on elbows in high sour gas fields显示文摘Sulfur particles carried by high-speed flow impact pipelines,which may cause equipment malfunctions and even failure.This paper investigates the scouring effect of mist gas containing sulfur particles on elbows in highly sour gas fields.The multiphase-flow hydrodynamic model of the 90elbow was established by using the computational fluid dynamics(CFD)method.The scouring effects of the gasliquid mist fluid with the water-liquid fraction of 20%and particles with the diameter of 0.01 e0.05mm on elbows were explored within the flow velocity range of 0e20 m/s.In addition,the influences of secondary collision,mean curvature radius to diameter(R/D)ratio,inertial force,drag force,and Stokes number on trajectories of sulfur particles were studied.Moreover,the influences of hydrodynamic parameters of multiphase flow on corrosion inhibitor film were analyzed with the wall shear stress as the reference value.Serious erosion mainly occurred in the extrados of elbow as well as the junction between downstream pipeline and the intrados of elbow,the maximum erosion area occurs at 61.9.When the incident position of the particle was far away from the top of the inlet plane,the probability of secondary collision became smaller.Furthermore,the erosion rate decreased with the rise in the R/D radio.The maximum erosion rate of elbow increased with the increase in the Stoke number.The maximum erosion rate reached 0.428 mm/a at 0.05mm particle diameter and 20 m/s fluid velocity.The wall shear stress increased with the increase in fluid velocity and mass flow rate of particle,the fitting function of the wall shear stress curve was the Fourier type.The results indicated that highvelocity particles had a serious erosion effect on elbows and affected the stability of the corrosion inhibitor film.The erosion effect could be retarded by controlling the velocity and diameter of particles.The results provided technical supports for the safe production in highly sour gas fields.Enbo Zhang Dezhi Zeng Hongjun Zhu Shuanggui Li Dongbo Chen Jie Li Yanyan Ding Gang Tian 2018Petroleum2018,4,2:5
7NIR light-induced tumor phototherapy using ICG delivery system based on platelet-membrane-camouflaged hollow bismuth selenide nanoparticles显示文摘Near-infrared(NIR)light-triggered photothermal therapy(PTT)is a promising treatment strategy for treating cancer.The combination of nanotechnology and NIR has been widely applied.However,the therapeutic efficacy of the drug-delivery system depends on their ability to avoid phagocytosis of endothelial system,cross the biological barriers,prolong circulation life,localize and rapidly release the therapeutic at target sites.In this work,we designed a platelet membrane(PM)-camouflaged hollow mesoporous bismuth selenide nanoparticles(BS NPs)loading with indocyanine green(ICG)(PM@BS-ICG NPs)to achieve the above advantages.PM-coating has active tumor-targe ting ability which could preve nt drug leakage and provide drug long circulation,causing drug delivery systems to accumulate in tumor sites effectively.Moreover,as a type of the photothermal sensitizers,BS NPs are used as the inner cores to improve ICG stability and are served as scaffolds to enhance the hardness of this drug delivery system.For one hand,the thermal vibration of BS NPs under NIR laser irradiation causes tumor inhibition through hyperthermia.For another hand,this hyperthermia process could damage PM and let ICG rapid release from PM@BS-ICG NPs.The in vitro and in vivo results showed that this biomimetic nano-drug delivery system exhibits obvious antitumor activity which has good application prospect.Kaili Ding Cuixia Zheng Lingling Sun Xinxin Liu Yanyan Yin Lei Wang 2020Chinese Chemical Letters2020,31,5:5
8Three-dimensional printing for heart diseases: clinical application review显示文摘Heart diseases remain the top threat to human health,and the treatment of heart diseases changes with each passing day.Convincing evidence shows that three-dimensional(3D)printing allows for a more precise understanding of the complex anatomy associated with various heart diseases.In addition,3D-printed models of cardiac diseases may serve as effective educational tools and for hands-on simulation of surgical interventions.We introduce examples of the clinical applications of different types of 3D printing based on specific cases and clinical application scenarios of 3D printing in treating heart diseases.We also discuss the limitations and clinically unmet needs of 3D printing in this context.Yanyan Ma Peng Ding Lanlan Li Yang Liu Ping Jin Jiayou Tang Jian Yang 2021Bio-Design and Manufacturing2021,4,3:3
9Responses of Yellow Sea Cold Water Mass to Typhoon Bolaven显示文摘A two-month seabed-mounted observation(YSG1 area) was carried out in the western Yellow Sea Cold Water Mass(YSCWM) using an RDI-300 K acoustic Doppler current profiler(ADCP) placed at a water depth of 38 m in late summer, 2012. On August 2012, Typhoon Bolaven passed east of YSG1 with a maximum wind speed of 20 m s-1. The water depth, bottom temperature, and profile current velocities(including u, v and w components) were measured, and the results showed that the typhoon could induce horizontal current with speed greater than 70 cm s-1 in the water column, which is especially rare at below 20 meters above bottom(mab). The deepening velocity shear layer had an intense shear velocity of around 10 cm s-1 m-1, which indicated the deepening of the upper mixed layer. In the upper water column(above 20 mab), westward de-tide current with velocity greater than 30 cm s-1 was generated with the typhoon's onshore surge, and the direction of current movement shifted to become southward. In the lower water column, a possible pattern of eastward compensation current and delayed typhoon-driven current was demonstrated. During the typhoon, bottom temperature variation was changed into diurnal pattern because of the combined influence of typhoon and tidal current. The passage of Bolaven greatly intensified local sediment resuspension in the bottom layer. In addition, low-density particles constituted the suspended particulate matter(SPM) around 10 mab, which may be transported from the central South Yellow Sea by the typhoon. Overall, the intensive external force of the Typhoon Bolaven did not completely destroy the local thermocline, and most re-suspended sediments during the typhoon were restricted within the YSCWM.LI Jianchao LI Guangxue XU Jishang QIAO Lulu MA Yanyan DING Dong LIU Shidong 2019Journal of Ocean University of China2019,18,1:3
10Simultaneous determination of ivabradine and N-desmethylivabradine in human plasma and urine using a LC-MS/MS method: application to a pharmacokinetic study显示文摘A sensitive and specific liquid-chromatography tandem mass spectrometry(LC-MS/MS)assay has been developed and validated for the simultaneous quantification of ivabradine and its active metabolite N-desmethylivabradine in human plasma and urine.The assay employed a single liquid–liquid extraction of the analytes from plasma and urine samples,and diazepam was used as internal standard(IS).The chromatographic separation was achieved on a Diamonsil C18 column(150 mm4.6 mm,5 mm,Dikma)using a mixture of methanol and aqueous 5 mM ammonium acetate buffer containing 0.2%formic acid(80:20,v/v)as mobile phase.The assay for ivabradine and N-desmethylivabradine in plasma showed good linearity(r≥0.99)over the ranges 0.1013–101.3 ng/mL and 0.085–25.5 ng/mL,respectively.The assay for ivabradine and N-desmethylivabradine in urine showed good linearity(r≥0.99)over the ranges 10.13–6078 ng/mL and 8.5–850 ng/mL,respectively.The intra-and inter-day accuracy and precision values were found to be within the assay variability limits(RSD<15%)in accordance with FDA guidelines.The methods were successfully used for evaluating the pharmacokinetic properties of ivabradine and N-desmethylivabradine in human plasma and urine in Chinese healthy volunteers.Chengtao Lu Yanyan Jia Jing Yang Xin Jin Ying Songa Wenxing Liu Yi Ding Xiaoli Sun Aidong Wen 2012Acta Pharmaceutica Sinica B2012,2,2:3
11Safety and efficacy of meplazumab in healthy volunteers and COVID-19 patients: a randomized phase 1 and an exploratory phase 2 trial显示文摘Recent evidence suggests that CD147 serves as a novel receptor for severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection.Blocking CD147 via anti-CD147 antibody could suppress the in vitro SARS-CoV-2 replication.Meplazumab is a humanized anti-CD147 IgG_(2) monoclonal antibody,which may effectively prevent SARS-CoV-2 infection in coronavirus disease 2019(COVID-19)patients.Here,we conducted a randomized,double-blinded,placebo-controlled phase 1 trial to evaluate the safety,tolerability,and pharmacokinetics of meplazumab in healthy subjects,and an open-labeled,concurrent controlled add-on exploratory phase 2 study to determine the efficacy in COVID-19 patients.In phase 1 study,59 subjects were enrolled and assigned to eight cohorts,and no serious treatment-emergent adverse event(TEAE)or TEAE grade≥3 was observed.The serum and peripheral blood Cmax and area under the curve showed non-linear pharmacokinetic characteristics.No obvious relation between the incidence or titer of positive anti-drug antibody and dosage was observed in each cohort.The biodistribution study indicated that meplazumab reached lung tissue and maintained>14 days stable with the lung tissue/cardiac blood-pool ratio ranging from 0.41 to 0.32.In the exploratory phase 2 study,17 COVID-19 patients were enrolled,and 11 hospitalized patients were involved as concurrent control.The meplazumab treatment significantly improved the discharged(P=0.005)and case severity(P=0.021),and reduced the time to virus negative(P=0.045)in comparison to the control group.These results show a sound safety and tolerance of meplazumab in healthy volunteers and suggest that meplazumab could accelerate the recovery of patients from COVID-19 pneumonia with a favorable safety profile.Huijie Bian Zhao-Hui Zheng Ding Wei Aidong Wen Zheng Zhang Jian-Qi Lian Wen-Zhen Kang Chun-Qiu Hao Jing Wang Rong-Hua Xie Ke Dong Jie-Lai Xia Jin-Lin Miao Wen Kang Guoquan Li Di Zhang Mingru Zhang Xiu-Xuan Sun Likun Ding Kui Zhang Junfeng Jia Jin Ding Zhiqin Li Yanyan Jia Lin-Na Liu Zhe Zhang Zhao-Wei Gao Hong Du Na Yao Qing Wang Ke Wang Jie-Jie Geng Bin Wang Ting Guo Ruo Chen Yu-Meng Zhu Li-Juan Wang Qian He Rui-Rui Yao Ying Shi Xiang-Min Yang Jian-Sheng Zhou Yi-Nan Ma Ya-Tao Wang Xue Liang Fei Huo Zhe Wang Yang Zhang Xu Yang Ye Zhang Lu-Hua Gao Ling Wang Xiao-Chun Chen Hao Tang Shuang-Shuang Liu Qing-Yi Wang Zhi-Nan Chen Ping Zhu 2021Signal Transduction and Targeted Therapy2021,6,6:2
12Coastal evolution of Yancheng, northern Jiangsu, China since the mid-Holocene based on the Landsat MSS imagery显示文摘自从 1970 年代,遥感图象为海岸线变化的描述和分析提供了新信息,特别集中于短 timescale 变化。基于 Landsat 女士形象,这份报纸集中于 Yancheng 的海岸线进化,北江苏,中国自从 mid-Holocene。一幅斑马条纹图象,能揭示 Yancheng 的古老的沿海的进化,从 Landsat 被提取女士图象。基于提取黑白人的条纹, 19 件表面沉积样品被恢复并且分析了认出这些条纹的沉积特征。它证明最,沙和淤泥的沙样品出现在白条纹上,当淤泥和淤泥的泥土样品在黑条纹上时。沙、泥泞的沉积在 Yancheng 沿海的平原上介绍一个轮流出现的分发模式。一张历史的海岸线地图根据 paleo 沿海的沙障碍和 paleo 海岸线的以前的研究成就被画,并且在斑马条纹图象上被附加。提取斑马条纹的趋势与历史的海岸线一致,并且它应该是 Yancheng 海岸线进化的标志。根据黑白人的条纹和以前的研究结果的十个集合,我们把 Yancheng 沿海的进化的前进划分了成三个阶段(即,早稳定的阶段( 6500 一BP广告 1128 ),快速的免职阶段(广告 11281855 )和调整阶段(广告1855礼品))。黑白人的条纹的十个集合在 Yancheng 沿海的平原上作为海岸线进化的典型模式被识别。KANG Yanyan XIA Fei DING Xianrong ZHANG Changkuan CHENG Ligang GE Xiaoping Jennifer GLASS 2013Journal of Geographical Sciences2013,23,5:2
13Comparison of carbonaceous particulate matter emission factors among different solid fuels burned in residential stoves显示文摘Guofeng Shen Miao Xue Yuanchen Chen Chunli Yang Wei Li Huizhong Shen Ye Huang Yanyan Zhang Han Chen Ying Zhu Haisuo Wu Aijun Ding Shu Tao 2014Atmospheric Environment2014,,:2
14Tyrosine phosphatase Shp2 regulates pi 15RhoGEF/Rhodependent dendritic cell migration显示文摘The orchestrated migration of dendritic cells(DCs)to secondary lymphoid organs relies on C-C chemokine receptor type 7(CCR7)and its ligand C-C motif chemokine ligand 19(CCL19),and DC migration to lymph nodes is crucial for the initiation and progression of adaptive immune responses.Yun Xu Yun Zhang Yanyan Yang Yanqi Liu Qiaoying Tian Pan Liu Zhifan Ding Hongqiang Cheng Xue Zhang Yuehai Ke 2021Cellular & Molecular Immunology2021,18,3:2
15Pulse combination and compression in hollow-core fiber for few-cycle intense mid-infrared laser generation显示文摘The generation of high-peak-power,few-cycle mid-infrared(MIR)pulses using coherent beam combination and nonlinear pulse compression techniques simultaneously is demonstrated.The two pulses,with identical pulse energy of 2.8 mJ and pulse duration of 160 fs,are coherently combined at the input end of a krypton-filled hollow-core fiber(HCF),and then the bandwidth of the combined pulse is broadened to near an optical octave due to strong phase modulations,and the temporal width is compressed into a few-cycle regime.Finally,a 2.7 mJ,22.9 fs,20 Hz laser at 4μm can be obtained,and the pulse peak power is greatly enhanced compared with that of conventional single-channel optical parametric chirped pulse-amplification systems.Furthermore,the peak power generated from this system has the prospect of further scaling up through use of more channels of coherent combination,which can pave a way to generate higher peak power ultra-intense MIR pulses for strong-field physics.Junyu Qian Pengfei Wang Yujie Peng Yanyan Li Beijie Shao Hongpeng Su Xinlin Lv Ding Wang Yuxin Leng Ruxin Li 2021Photonics Research2021,9,4:2
16BUB1B and circBUB1B_544aa aggravate multiple myeloma malignancy through evoking chromosomal instability显示文摘Multiple myeloma(MM)is an incurable plasma cell malignancy in the bone marrow characterized by chromosome instability(CIN),which contributes to the acquisition of heterogeneity,along with MM progression,drug resistance,and relapse.In this study,we elucidated that the expression of BUB1B increased strikingly in MM patients and was closely correlated with poor outcomes.Overexpression of BUB1B facilitated cellular proliferation and induced drug resistance in vitro and in vivo,while genetic targeting BUB1B abrogated this effect.Mechanistic studies unveiled that enforced expression of BUB1B evoked CIN resulting in MM poor outcomes mainly through phosphorylating CEP170.Interestingly,we discovered the existence of circBUB1B_544aa containing the kinase catalytic center of BUB1B,which was translated by a circular RNA of BUB1B.The circBUB1B_544aa elevated in MM peripheral blood samples was closely associated with MM poor outcomes and played a synergistic effect with BUB1B on evoking CIN.In addition,MM cells could secrete circBUB1B_544aa and interfere the MM microenvironmental cells in the same manner as BUB1B full-length protein.Intriguingly,BUB1B siRNA,targeting the kinase catalytic center of both BUB1B and circBUB1B_544aa,significantly inhibited MM malignancy in vitro and in vivo.Collectively,BUB1B and circBUB1B_544aa are promising prognostic and therapeutic targets of MM.Xiaozhu Tang Mengjie guo Pinggang Ding Zhendong Deng Mengying Ke Yuxia Yuan Yanyan Zhou Zigen Lin Muxi Li Chunyan Gu Xiaosong Gu Ye Yang 2021Signal Transduction and Targeted Therapy2021,6,11:2
17Temporal-Spatial Variation of Surface Suspended Matter and Controlling Factors in the Inner Shelf of the East China Sea in Winter显示文摘Based on the observed surface suspended matter in the East China Sea in February 2007 and June 2015, an empirical model was established using L1 b's band 4 data to retrieve surface suspended matter from the Moderate Resolution Imagine Spectroradiometer Terra imagery. The squared correlation coefficient is 0.8358, and the root mean square error is 0.4285 mg L-1. The model reflects the distribution characteristics of surface suspended matter in the inner shelf of the East China Sea. In this paper, the satellite images of the study area were retrieved in January from 2001 to 2015, and the monthly distribution of surface suspended matter were obtained. The inter-annual distribution of the study area is similar, and the concentration of surface suspended matter is higher near the shore than offshore. A large amount of surface suspended matter is transported southeast under the influence of Zhejiang and Fujian coastal current and Taiwan warm current. Only a small amount of surface suspension can reach the Kuroshio area. The surface suspended matter concentration changes obviously near the estuary because of the effect of differences in the flux of the Yangtze River. Meanwhile, winter monsoon, temperature front, El Ni?o events, and other factors affect the distribution of surface suspended matter in 100 m isobath to coastal water but minimally influence the distribution in 100 m isobath to deep sea.MIN Jianxiong LI Guangxue DING Dong QIAO Lulu MA Yanyan YANG Gang ZHANG Yaqi ZHANG Lei LI Shuhao 2019Journal of Ocean University of China2019,18,1:2
18Determination of ifenprodil by LC–MS/MS and its application to a pharmacokinetic study in healthy Chinese volunteers显示文摘This paper reports the development and validation of an assay for ifenprodil based on liquid chromatography–tandem mass spectrometry(LC–MS/MS)and its application to a pharmacokinetic study involving single and multiple intravenous infusions to healthy Chinese volunteers.After sample preparation of plasma by liquid–liquid extraction with ethyl acetate,the analyte and internal standard,urapidil,were separated by reversed phase chromatography in a run time of 4 min and detected by positive ion electrospray ionization followed by multiple reaction monitoring of the precursor-to-product ion transitions at m/z 326.2-308.1 for ifenprodil and m/z 388.4-205.3 for IS.The assay was linear in the concentration range 0.2–50.0 ng/mL with recovery 476.4%.In the pharmacokinetic study of single intravenous infusions of 5,10 and 15 mg ifenprodil,peak plasma concentrations and areas under the plasma concentration–time curve were both linearly related to dose.In the pharmacokinetic study of multiple once daily intravenous infusions of 10 mg ifenprodil for 7 days,pharmacokinetic parameters were similar to those after the single dose showing that ifenprodil does not accumulate on repeated administration.Jing Yang Chengtao Lu Wei Song Jiankang Li Yi Ding Yanrong Zhu Jinyi Cao Likun Ding Yanyan Jia Aidong Wen 2013Acta Pharmaceutica Sinica B2013,3,3:2
19CpG ODN107 potentiates radiosensitivity of human glioma cells via TLR9-mediated NF-κB activation and NO production显示文摘Xiaoli Li Dan Liu Xin Liu Weiwei Jiang Weiying Zhou Wei Yan Yanyan Cen Bin Li Guanqun Cao Guofu Ding Xueli Pang Jianguo Sun Jiang Zheng Hong Zhou 2012Tumor Biology2012,,5:1
20Levonorgestrel Inhibits Human Endometrial Cell Proliferation through the Upregulation of Gap Junctional Intercellular Communication via the Nuclear Translocation of Ser255 Phosphorylated Cx43显示文摘Xiaomiao Zhao Xueliang Tang Tingting Ma Miao Ding Lijuan Bian Dongmei Chen Yangzhi Li Liangan Wang Yanyan Zhuang Meiqing Xie Dongzi Yang Ignacio Zapardiel 2015BioMed Research International2015,,:1
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