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| 1 | Opening and evolution of the South China Sea constrained by studies on volcanic rocks:Preliminary results and a research design显示文摘The South China Sea (SCS) is characterized by abundant seamounts, which provide important information about the evolution of the SCS and related deep processes. Cenozoic volcanism in the SCS and its surroundings comprises three stages relative to the spreading of the SCS:prespreading (>32 Ma), syn-spreading (32-16 Ma), and post-spreading (<16 Ma). The pre-spreading magmatism predominantly occurs on the northern margin of the SCS and in South China coastal areas and shows a bi-modal affinity. The syn-spreading magmatic activity was very limited on the periphery of the SCS, but may be concentrated in the SCS. However, seafloor samples of this stage are not available yet because of overlying thick sedimentary deposits. Post-spreading magmatism is widespread in the central and southwest sub-basins of the SCS, Hainan Island, Leizhou Peninsula, Thailand, and Vietnam. These are mainly alkali basalts with subordinate tholeiites, and display OIB-type geochemical characteristics. The Dupal isotope anomaly and presence of high-magnesian olivine phenocrysts suggests their possible derivation from the Hainan mantle plume. The temporal and spatial distribution of Cenozoic volcanism in the SCS and its surroundings may be accounted for either by plate stress re-organization before and after SCS spreading, or by ridge suction of plume flow during opening of the SCS. If the latter is the case, the volcanic rocks within the SCS basin may not be typical mid-ocean ridge basalts (MORB). It remains puz-zling, however, that the transition between the South China continental margin and the SCS basin does not have features typical of a volcanic rifted margin. Clearly, the relationship between mantle plume and SCS opening needs further evaluation. A better un-derstanding of the link between deep processes and opening of the SCS not only requires enhanced studies on igneous petrogene-sis, but also is heavily dependent on systematic sampling of seafloor rocks. | XU YiGang WEI JingXian QIU HuaNing ZHANG HuiHuang HUANG XiaoLong | 2012 | Chinese Science Bulletin2012，57，24： | 43 |
| 2 | Precise measurement of stable (δ^(88/86)Sr) and radiogenic (^(87)Sr/^(86)Sr) strontium isotope ratios in geological standard reference materials using MC-ICP-MS显示文摘A new method for high-precision measurements of stable (δ88/86Sr) and radiogenic (87Sr/86Sr) Sr isotope ratios was developed on the MC-ICP-MS using a standard-sample-standard bracketing protocol. By carefully monitoring and controlling the accumulation of the on-peak backgrounds (i.e. the carryover memory) on the instrument, our method can provide an external precision of around 0.010‰ to 0.014‰ for 88/86 Sr measurements. Such precision is comparable to that achieved by double-spike TIMS method (DS-TIMS), and 2-3 times better than those of the previously reported results by MC-ICP-MS without spiking. The results of the standard seawater IAPSO are also identical to those by DS-TIMS. However, our method is more advantageous, efficient and convenient to use for routine Sr isotopic analysis than the DS-TIMS method as there is no need to prepare and calibrate the 84Sr-87 Sr double spike. Using this method, we measured the δ88/86Sr values in a series of international geological rock standards, which show large variability, with the lowest value (0.20‰) registered in JG-2, a terrestrial granite, and the highest value (0.539‰) in UB-N, a serpentinite. This may provide an additional means for isotopic characterization of geological processes, adding a new dimension over the traditional use of radiogenic Sr isotopic ratio 87Sr/86Sr. | MA JinLong WEI GangJian LIU Ying REN ZhongYuan XU YiGang YANG YongHong | 2013 | Chinese Science Bulletin2013，58，25： | 9 |
| 3 | Molecular phylogeny of coronaviruses including human SARS-CoV显示文摘Phylogenetic tree of coronaviruses (CoVs) in-cluding the human SARS-associated virus is reconstructed from complete genomes by using our newly developed K- string composition approach. The relation of the human SARS-CoV to other coronaviruses, i.e. the rooting of the tree is suggested by choosing an appropriate outgroup. SARS-CoV makes a separate group closer but still distant from G2 (CoVs in mammalian host). The relation between different isolates of the human SARS virus is inferred by first constructing an ultrametric distance matrix from counting sequence variations in the genomes. The resulting tree is consistent with clinic relations between the SARS-CoV isolates. In addition to a larger variety of coronavirus ge-nomes these results provide phylogenetic knowledge based on independent novel methodology as compared to recent phylogenetic studies on SARS-CoV. | GAO Lei QI Ji WEI Haibin SUN Yigang HAO Bailin | 2003 | Chinese Science Bulletin2003，48，12： | 7 |
| 4 | Outbreaks of Acute Respiratory Disease Associated with Human Adenovirus Infection in Closed Camps,China,December 2011–March 2014显示文摘Summary What is already known on this topic?Human adenovirus(HAdV)was frequently associated with acute respiratory disease(ARD)outbreaks in military camps.What is added by this report?HAdV-B7,HAdV-B14,and HAdV-B55 were determined to be responsible for 3,2,and 4 ARD outbreaks in military camps,China,respectively,with a total attack rate of 28.0%during 2011 to 2014. | Juan Du Xiaodong Zhao Fang Tang Doudou Huang Guangqian Pei Xiaoai Zhang Baogui Jiang Qingbin Lu Wei Liu Yigang Tong | 2021 | China CDC weekly2021，3，38： | 4 |
| 5 | High-throughput sequencing exclusively identified a novel Torque teno virus genotype in serum of a patient with fatal fever显示文摘Torque teno virus(TTV) has been found to be prevalent world-wide in healthy populations and in patients with various diseases, but its etiological role has not yet been determined. Using high-throughput unbiased sequencing to screen for viruses in the serum of a patient with persistent high fever who died of suspected viral infection and prolonged weakness, we identified the complete genome sequence of a TTV(isolate Hebei-1). The genome of TTV-Hebei-1 is 3649 bp in length, encoding four putative open reading frames, and it has a G+C content of 49%. Genomic comparison and a BLASTN search revealed that the assembled genome of TTV-Hebei-1 represented a novel isolate, with a genome sequence that was highly heterologous to the sequences of other reported TTV strains. A phylogenetic tree constructed using the complete genome sequence showed that TTV-Hebei-1 and an uncharacterized Taiwan Residents strain, TW53A37, constitute a new TTV genotype. The patient was strongly suspected of carrying a viral infection and died eventually without any other possible causes being apparent. No virus other than the novel TTV was identified in his serum sample. Although a direct causal link between the novel TTV genotype infection and the patient's disease could not be confirmed, the findings suggest that surveillance of this novel TTV genotype is necessary and that its role in disease deserves to be explored. | Zhiqiang Mi Xin Yuan Guangqian Pei Wei Wang Xiaoping An Zhiyi Zhang Yong Huang Fan Peng Shasha Li Changqing Bai Yigang Tong | 2014 | Virologica Sinica2014，29，2： | 4 |
| 6 | Development of Solar Spectroradiometer for Meteorological Observation显示文摘A newgeneration of solar spectroradiometer has been developed by CUST/JRSI to improve solarirradiance observation data under hyperspectral resolution. It is based on the grating spectroradiometer with a back-thinned CCD linear image sensor and is operated in a hermetically sealed enclosure. The solar spectroradiometer is designed to measure the solar spectral irradiance from300 nm to 1100 nm wavelength range with the spectral resolution of 2 nm( the full width at half maximum). The optical bench is optimized to minimize stray light. The Peltier device is used to stabilize the temperature of CCD sensor to 25℃,while the change of temperature of CCD sensor is controlled to ±1℃ by the dedicated Peltier driver and control circuit. | Liu Liying Zheng Feng Zhang Guoyu Xu Yigang Yang Liyan Lyu Wenhua Bian Zeqiang Chong Wei Li Ye | 2017 | Instrumentation2017，4，1： | 3 |
| 7 | Identification of Histoplasma causing an unexplained disease cluster in Matthews Ridge, Guyana显示文摘Here,we report the identification of Histoplasma causing an unexplained disease cluster in Matthews Ridge,Guyana.In March 2019,14 employees of Chongqing Bosai Mining Company,China,working in a manganese mining of Guyana,had unexplained fever,and two of them died.We obtained lung and brain tissues as well as the blood samples from the two deceased cases(patient No.1 and 2),and bronchoscopy lavages and cerebrospinal fluid samples from one severe case(patient No.3),respectively.All samples were tested by pathological examination,high-throughput sequencing,and real-time PCR.Pathological detection showed the presence of spore-like structures in the lung tissue of patient No.1,indicating a fungal infection in this patient.Nanopore sequencing identified the existing of H.capsulatum in the lung tissue sample within 13 h.Next-generation sequencing identified specific fragments of H.capsulatum in all of the samples tested(lung,brain and blood serum from the deceased cases,and plasma from the severe case).Real-time PCR assays did not reveal any viral infection related to transmission from bat feces.We conclude that H.capsulatum was the causative pathogen of this disease cluster based on epidemiologic,clinical,pathological and nucleic acid evidence. | Ji Wang Weimin Zhou Hua Ling Xiaoping Dong Yi Zhang Jiandong Li Yong Zhang Jingdong Song William J.Liu Yang Li Ruiqing Zhang Wei Zhen Kun Cai Shuangli Zhu Dongyan Wang Jinbo Xiao Yigang Tong Wenli Liu Lihua Song Wei Wu Yang Liu Xiang Zhao Ruihuan Wang Sheng Ye Jing Wang Roujian Lu Baoying Huang Fei Ye Wenwen Lei Rongbao Gao Qi Shi Cao Chen Jun Han Wenbo Xu George F.Gao Xuejun Ma Guizhen Wu | 2019 | Biosafety and Health2019，1，3： | 3 |
| 8 | Identification, expression, and characterization of the highly conserved D-xylose isomerase in animals显示文摘d 木糖是为动物的必要的糖。从一个软体动物的 xylanase, Ampullaria crossean,被我们的实验室以前报导。这 xylanase 能降级木聚糖进 d 木糖。但是仍然在我们它的新陈代谢的小径上的知识有差距。问题是木糖怎么进入戊糖小径吗?在 genomic 数据库和生物信息的工具的帮助下,我们发现一些动物例如细菌,有高度保存的 d 木糖 isomerase (EC 5.3.1.5 ) 。从海喷射的木糖 isomerase, Ciona intestinalis,不同类地在 Escherichia coli 被表示并且净化了证实它的功能。recombinant 酶面对 Mg2+ 有好热稳定性。在最佳温度和最佳 pH 环境,它 d 木糖上的特定的活动是 0.331 mol/mg/min。这酶在许多广泛地存在动物,而是它消失在像两栖纲的 Xenopus laevis 的染色体。它的顺序高度被保存。从动物的木糖 isomerases 是为进化的学习的很有趣的蛋白质。 | Ming Ding Yigang Teng Qiuyu Yin Wei Chen Fukun Zhao | 2009 | Acta Biochimica et Biophysica Sinica2009，41，2： | 3 |
| 9 | Comparative study on the weight loss and lipid metabolism by tea polyphenols in diet induced obese C57BL/6J pseudo germ free and conventionalized mice显示文摘The role of gut microbiota in terms of host health is becoming increasingly important.In this study,the comparative effects of tea polyphenols(TPs)on weight loss and lipid metabolism on conventionalized mice(CVZ)and pseudo germ-free(PGF)mice(treated with antibiotics)were investigated.Our findings revealed that high fat(HF)diet considerably increased the body weight,total fat and upsurge lipid indices in CVZ mice but PGF mice were not sensitive to the effect of HF diet as CVZ mice.After the dietary administration of TP,body weight,perirenal fat and epididymal fat,liver weight,glucose(GLU)level,total chloestrol(TC level),high density lipoprotein-cholesterol(HDL-C)level significantly lowered in PGF mice as compared to CVZ mice group.However,the area of fat cells and triglyceride(TG)level were significantly increased in PGF mice.In CVZ mice,TP intervention resulted in a considerable drop in the Firmicutes/Bacteroides ratio as compared to PGF mice.The intestinal flora of PGF mice was severely reduced after antibiotic treatment,while TP administration restored intestinal diversity;the abundance of Akkermansia and Lactobacillus increased,whereas the abundance of Enterobacteriaceae and Prevotella reduced.Overall,we can assume that PGF obese mice administered with TP have less anti-obesity effects compared to obese CVZ mice. | Kashif Hussain Yingying Yang Jie Wang Hengjuan Bian Xi Lei Junjie Chen Qianying Li Li Wang Qingping Zhong Xiang Fang Yutao Wang Hong Wei Yigang Tong Zhenlin Liao | 2022 | Food Science and Human Wellness2022，11，3： | 2 |
| 10 | Experimental and CFD study of unsteady airborne pollutant transport within an aircraft cabin mock-up显示文摘 | Yah Wei Zhang Yuanhui Sun Yigang | 2009 | Building and Environment2009，44，1： | 1 |
| 11 | Experimental and CFD study of unsteady airborne pollutant transport within an aircraft cabin mock-up显示文摘 | Yah Wei Zhang Yuanhui Sun Yigang | | 0，，01： | 1 |
| 12 | Loss of MiR-223 duplex (5p and 3p) aggravates myocardial depression and mortality in polymicrobial sepsis显示文摘 | Xiaohong Wang Wei Huang Yang Yang Yigang Wang Tianqing Peng Jiang Chang Charles C. Caldwell Basilia Zingarelli Guo-Chang Fan | 2014 | BBA - Molecular Basis of Disease2014，，： | 1 |
| 13 | Changes of Aroma Components in 'Keitt' Mango during the Postharvest Period显示文摘[Objective]This study aimed to investigate the changes of aroma components in mango fruit at different post-harvest stages.[Method]The aroma components in‘Keitt'mango fruit at 3,6,9 and 13 d postharvest were extracted using head-space solid phase microextraction( HS-SPME) and analyzed by gas chromatograph-mass spectrophotometer( GC-MS).[Result]The results showed that a total of 42 aroma compounds were identified from the mango samples at four stages. To be specific,monoterpene and sesquiterpene were the major components; at 3,6,9 and 13 d postharvest,the relative contents of terpene were 94. 24%,98. 91%,55. 32% and 95. 97%,respectively.[Conclusion]1S-( +)-3-carene is the characteristic aroma component in ripe fruit of‘Keitt'mango. The aroma of mango fruit is also affected by ester,alcohol and aldehyde compounds. | Yigang ZHOU Hongxia WU Quansheng YAO Songbiao WANG Changbin WEI Xiaowei MA | 2014 | Agricultural Biotechnology2014，3，2： | 1 |
| 14 | Meta‐analysis of prospective studies on the effects of nut consumption on hypertension and type 2 diabetes mellitus 对食用坚果对高血压和2型糖尿病的影响的前瞻性研究进行的meta分析显示文摘 | Kai Guo Zhiwen Zhou Yibo Jiang Wei Li Yigang Li | 2015 | Journal of Diabetes2015，，： | 1 |
| 15 | Mobilization and redistribution of major and trace elements during extreme weathering of basalt in Hainan Island, South China 显示文摘 | Ma Jinlong Wei Gangjian Xu Yigang | 2007 | Geochimica et Cosmochimica Acta2007，71，13： | 1 |
| 16 | Djrho2 is involved in regeneration of visual nerves in Dugesia japonica显示文摘The freshwater planarian is a powerful animal model for studying regeneration and stem cell activity in vivo.During regeneration,stem cells(neoblasts in planarian) migrated to the wounding edge to re-build missing parts of the body.However,proteins involved in regulating cell migration during planarian regeneration have not been studied extensively.Here we report two small GTPase genes(Djrho2 and Djrho3) of Dugesia japonica(strain Pek-1).In situ hybridization results indicated that Djrho2 was expressed throughout the body with the exception of the pharynx region while Djrho3 was specifically expressed along the gastro-vascular system.Djrho2 was largely expressed in neoblasts since its expression was sensitive to X-ray irradiation.In Djrho2-RNAi planarians,smaller anterior blastemas were observed in tail fragments during regeneration.Consistently,defective regeneration of visual nerve was detected by immunostainning with VC-1 antibody.These results suggested that Djrho2 is required for proper anterior regeneration in planairan.In contrast,no abnormality was observed after RNAi of Djrho3.We compared protein compositions of control and Djrho2-RNAi planarians using an optimized proteomic approach.Twenty-two up-regulated and 26 de-regulated protein spots were observed in the two-dimensional electrophoresis gels,and 17 proteins were successfully identified by Mass Spectrometry(MS) analysis.Among them,6 actin-binding or cytoskeleton-related proteins were found de-expressed in Djrho2-RNAi animals,suggesting that abnormal cytoskeleton assembling and cell migration were likely reasons of defected regeneration. | Changxin Ma Yang Gao Guoliang Chai Hanxia Su Niejun Wang Yigang Yang Chunbo Li Di Miao Wei Wu | 2010 | Journal of Genetics and Genomics2010，37，11： | 1 |
| 17 | Upregulated H19 contributes to bladder cancer cell proliferation by regulating ID2 expression显示文摘 | Ming Luo Zuowei Li Wei Wang Yigang Zeng Zhihong Liu Jianxin Qiu | 2013 | FEBS J2013，，： | 1 |
| 18 | Scientific objectives and payload configuration of the Chang’E-7 mission显示文摘As the cornerstone mission of the fourth phase of the Chinese Lunar Exploration Program,Chang’E-7(CE-7)was officially approved,and implementation started in 2022,including a main probe and a communication relay satellite.The main probe,consisting of an orbiter,a lander,a rover and a mini-flying probe,is scheduled to be launched in 2026.The lander will land on Shackleton crater’s illuminated rim near the lunar south pole,along with the rover and mini-flying probe.The relay satellite(named Queqiao-2)will be launched in February 2024 as an independent mission to support relay communication during scientific exploration undertaken by Chang’E-4,the upcoming Chang’E-6 in 2024 and subsequent lunar missions.The CE-7 mission is mainly aimed at scientific and resource exploration of the lunar south pole.We present CE-7’s scientific objectives,the scientific payloads configuration and the main functions for each scientific payload with its key technical specifications. | Chi Wang Yingzhuo Jia Changbin Xue Yangting Lin Jianzhong Liu Xiaohui Fu Lin Xu Yun Huang Yufen Zhao Yigang Xu Rui Gao Yong Wei Yuhua Tang Dengyun Yu Yongliao Zou | 2024 | National Science Review2024，11，2： | 0 |
| 19 | Back to Science in Searching for SARS-CoV-2 Origins显示文摘In recent decades,emerging and re-emerging human-infecting pathogens have been represented as huge threats to public health and have become a global concern(1).After outbreaks of two coronaviruses(CoVs),severe acute respiratory syndrome coronavirus(SARS-CoV)and Middle East respiratory syndrome coronavirus(MERS-CoV),severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)became the first-known pandemic hastening CoV with tremendous wrecking to the world(2).The origin tracing of these emerging pathogens is of great significance in infectious disease prevention and control(3–4).The origin of SARS-CoV-2 remains elusive after the more than 3-year pandemic,though scientists around the world are making great efforts.From the experience of studying many other infectious pathogens,origin tracing is systematic and time-consuming work.The supposed origins of many infectious pathogens are still in debate,including SARS-CoV and human immunodeficiency virus,etc(5). | William J Liu Wenwen Lei Xiaozhou He Peipei Liu Qihui Wang Zhiqiang Wu Yun Tan Shuhui Song Gary Wong Jian Lu Jingkun Jiang Qiang Wei Mingkun Li Juncai Ma Xiaozhong Peng Yixue Li Baoxu Huang Yigang Tong Jun Han Guizhen Wu | 2023 | China CDC weekly2023，5，14： | 0 |
| 20 | The special issue:“Financial innovation for Emission Trading Scheme”显示文摘Against the existential and ubiquitous threat of climate changes to the environment,human health,and economic well-being,the proliferation of carbon neutrality from both government and private sector recently prevails in order to strengthen preparedness for the future global crisis.More than 70 countries and regions have pledged to achieve the goal of carbon neutrality by 2050(ICAP,2020).While the momentum toward adopting carbon neutrality targets continue to build,a growing body of countries and subnational governments move toward carbon pricing through rolling out,speeding-up,or strengthening the construct of emission trading scheme(ETS)and carbon financial market.Notwithstanding the laudable objectives of ETS to enable emission reduction,the potential of ETS is still largely untapped,largely stemming from poor financial innovation.This special issue is,therefore,aimed at promoting research on the carbon financial innovations,financial derivatives services,the use of Fintech and the optimization on architectures of the ETS such that ETSs could drive the transformation toward low-carbon development path and the achievement of Carbon Neutrality targets. | Ying Fan Yigang Wei Liang Xu Xiaoguang Chen Xi Liang | 2023 | Financial Innovation2023，9，1： | 0 |
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