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| 1 | MiR-181b suppresses proliferation of and reduces chemoresistance to temozolomide in U87 glioma stem cells显示文摘MicroRNAs regulate self renewal and differentiation of cancer stem cells.There,we sought to identify the expression of miR-181b in glioma stem cells and investigate the biological effect of miR-181b on glioma stem cells in this study.MiR-181b expression was measured by real-time PCR in glioma stem cells isolated from U87 cells by FACS sorting.After miR-181b was overexpressed in U87 glioma stem cells by miR-181b lentiviral expression vector and/or treatment of temozolomide,secondary neurosphere assay,soft agar colony assay and MTT assay were performed.Compared with U87 cells,the expression of miR-181b was significantly decreased in U87 glioma stem cells.Overexpression of miR-181b decreased neurosphere formation by U87 glioma stem cells in vitro and suppressed colony formation in soft agar,and the cell growth inhibition rates increased in a time-dependent manner in U87 glioma stem cells infected with miR-181b lentivirus.Furthermore,miR-181b had a synergistic effect on temozolomide-induced inhibition of secondary neurosphere and soft agar colony,and on cell growth inhibition rates.MiR-181b functions as a tumor suppressor that suppresses proliferation and reduces chemoresistance to temozolomide in glioma stem cells. | Ping Li Xiaoming Lu Yingyi Wang Lihua Sun Chunfa Qian Wei Yan Ning Liu Yongping You Zhen Fu | 2010 | The Journal of Biomedical Research2010，24，6： | 14 |
| 2 | Growth Characteristics and Reinforcing Behavior of In-situ NbCp in Laser Cladded Fe-based Composite Coating显示文摘Over the past decade,researchers demonstrated much interest in laser cladded metal matrix composite coatings for its good wear resistance.In this paper,in-situ NbCp reinforced Fe-based wear-resistance coatings with different designed NbC contents were produced by laser cladding.The formation mechanism of NbC particle was analyzed.The effects of NbC content on the microstructure and mechanical properties of coatings were investigated.It was revealed that α-(Fe,Cr),(Fe,Cr)_7C_3,NbC existed in all coatings.NbC particles formed by the chemical reaction of Nb and C dissolved in the molten pool.The increase of designed NbC content led to the growth of the porosity amount,and the increase of the size and the area ratio of the particle,as well as the transformation of the NbCp morphology from quadrangle to petaloid shape.Moreover,the micro-hardness and the wear resistance of the coating were improved with the increase of NbC.When NbCp content was 30 wt%,the mechanical properties decreased slightly. | Qingtang Li Yongping Lei Hanguang Fu | 2015 | Journal of Materials Science & Technology2015，31，7： | 4 |
| 3 | Reduced intensity conditioning and co-transplantation of unrelated peripheral stem cells combined with umbilical cord mesenchymal stem/stroma cells for young patients with refractory severe aplastic anemia显示文摘 | Yuewen Fu Qian Wang Jian Zhou Shengquan Liu Baijun Fang Xudong Wei Yongping Song | 2013 | International Journal of Hematology2013，，6： | 2 |
| 4 | Environmentally friendly solders 3-4 beyond Pb-based systems显示文摘Based on environmental considerations, global economic pressures, enacted by legislations in several countries, have warranted the elimination of lead from solders used in electronic applications. Sn3.5Ag, SnAgCu, and Sn0.7Cu have emerged among various lead-free candidates as the most promising solder alloys to be utilized in microelectronic industries. However, with the vast development and miniaturization of modern electronic packaging, new requirements such as superior service capabilities have been posed on lead-free solders. In order to improve the comprehensive property of the solder alloys, two possible approaches were adopted in the current research and new materials developed were patented. One approach was involved with the addition of alloying elements to make new ternary or quaternary solder alloys. Proper addition of rare earth element such as La and Ce have rendered solder alloys with improved mechanical properties, especially creep rupture lives of their joints. Another approach, the composite approach, was developed mainly to improve the service temperature capability of the solder alloys. Composite solders fabricated by mechanically incorporating various reinforcement particles to the solder paste have again exhibited enhanced properties without altering the existing processing characteristics. The recent progress and research efforts carried out on lead-free solder materials in Beijing University of Technology were reported. The effects of rare earth addition on the microstructure, processing properties, and mechanical properties were presented. The behaviors of various Sn-3.5Ag based composite solders were also explicated in terms of the roles of reinforcement particles on intermetallic growth, steady-state creep rate, the onset of tertiary creep, as well as the overall creep deformation in the solder joints. Thermomechanical fatigue (TMF) behavior of the solder alloys and composite solders were investigated with different parameters such as ramp rate, dwell time, etc. The damage accumulation features and residual mechanical properties of the thermomechanically-fatigued composite solder joints were compared with non-composite solder joints. To match the lead-free alloys, various types of water soluble no-clean soldering flux have also been developed and their properties were presented. | GAO Yuan LIU Peng GUO Fu XIA Zhidong LEI Yongping SHI Yaowu | 2006 | Rare Metals2006，25，z2： | 2 |
| 5 | 2021 Chinese consensus on the diagnosis and management of primary immune thrombocytopenia in pregnancy显示文摘Immune thrombocytopenia(ITP)is an acquired disease characterized by isolated thrombocytopenia,which is one of the most common causes of thrombocytopenia during pregnancy.Women with ITP who have severe thrombocytopenia are at an increased risk for life-threatening obstetric complications.Therefore,we established this consensus statement on the diagnosis and management of ITP during pregnancy(detailed information is available in the Supplementary File,http://gffzz16e312a87a7141a5hbopnf50nwbfo6vf5.ffgz.tsg.suse.edu.cn/A978). | Zhang Xiaohui Chen Fangping Chen Xiequn Cheng Yunfeng Fang Meiyun Feng Jianming Fu Haixia Gao Hong Han Yue He Aili Hou Ming Hu Yu Huang Ruibin Huang Wenrong Jing Zhicheng Kong Peiyan Liang Aibin Liang Meiying Liu Daihong Liu Junling Liu Lin Liu Xiaowei Ma Liangming Mei Heng Ni Heyu Niu Ting Peng Jun Qiao Jianlin Ren Jinhai Song Yongping Tang Liang V Tong Tong Wang Shaoyuan Wang Xin Wang Zhao Wei Hui Wu Depei Wu Guangsheng Xu Caigang Xu Xue Xu Yajing Yang Linhua Yang Renchi Yang Tonghua Yin Chenghong Yu Li Zhang Guangsen Zhang Lei Zhang Liansheng Zhang Xi Zhao Weili Zhao Yongqiang Zhou Daobin Zhou Hu Zhou Zeping Zhu Tienan Wang Jianliu Huang Xiaojun | 2022 | Chinese Medical Journal2022，，8： | 2 |
| 6 | Characterization of a Novel Weak Allele of RGA1/D1 and Its Potential Application in Rice Breeding显示文摘Semi-dwarfing improves the lodging resistance and yield of rice,and the vast majority of modern rice varieties harbor the sd1 allele to decrease plant height,resulting in reduced genetic diversity and negative agronomic traits.Thus,exploring alternative sources of dwarfism is imperative for rice breeding.Here,we identified a novel RGA1 allele,d1-w,from a local indica variety Xiaolixiang(XLX)using a map-based cloning approach.Compared with other rice varieties,RGA1 in XLX contained a unique single nucleotide polymorphism that resulted in an additional transcript and reduced functional RGA1 transcript level.The RGA1 from Nipponbare was introduced into XLX to estimate the value of d1-w in rice breeding.Compared with transgenic XLX plants(XLX^(D1)),XLX exhibited reduced plant height,increased stem strength,lower reactive oxygen species accumulation,delayed senescence,stronger photosynthesis,higher grain yield and quality(including external,milling and nutritional qualities),and enhanced resistance to drought and Rhizoctonia solani.Therefore,we proposed that the d1-w allele has potential as an excellent dwarfism resource for rice breeding. | LIU Yantong LI Ting JIANG Zhishu ZENG Chuihai HE Rong QIU Jiao LIN Xiaoli PENG Limei SONG Yongping ZHOU Dahu CAI Yicong ZHU Changlan FU Junru HE Haohua XU Jie | 2022 | Rice science2022，29，6： | 2 |
| 7 | Single-crystal microplates of two-dimensional organic-inorganic lead halide layered perovskites for optoelectronics显示文摘器官无机的混合 perovskites 在高效率的太阳能电池和轻排放由于他们的应用吸引可观的注意。与三维的 perovskites 相比,二维(2D ) 分层的混合 perovskites 有一个更高的激子绑定精力和潜在地更高的轻排放的效率。因为他们能是为综合光电子的合适的积木,有明确的 nanoscale 形态学的高质量的水晶的 2D perovskites 的生长是合乎需要的并且(nano ) photonics。此处,我们基于 2-phenylethylammonium 报导 2D perovskites 的单个水晶的 microplates 的灵巧的答案生长( C 6 H 5 CH 2 CH 2 NH 3+,豌豆)阳离子,(豌豆) 2 PbX 4( X = Br ,我),与通过一个溶解再结晶过程的明确的矩形的几何学和 nanoscale 厚度。水晶结构(豌豆)2 PbX 4 首先用单个水晶的 X 光检查衍射被证实。一个答案阶段运输生长过程被开发在与与铅醋酸盐先锋电影涂的底层不同的另一干净底层上与几百纳米的十测微计和厚度的一种典型尺寸种 microplates。表面地形学分析建议 2D microplates 的形成被婚礼蛋糕生长机制多半驾驶。通过卤化物 alloying,光致发光排放(豌豆)2 Pb (Br,我) 有狭窄的山峰带宽的 4 perovskites 乐意地被调节从紫(~ 410 nm ) 到绿色(~ 530 nm ) 。 | Dewei Ma Yongping Fu Lianna Dang Jianyuan Zhai Ilia A. Guzei Song Jin | 2017 | Nano Research2017，10，6： | 2 |
| 8 | 查看详情显示文摘 | FU Yongping LI Yunde | | 0，，： | 1 |
| 9 | 查看详情显示文摘 | FU Yongping LI Yunde | | 0，，： | 1 |
| 10 | 查看详情显示文摘 | FU Yongping LI Yunde | | 0，，： | 1 |
| 11 | Microstructure Evolution of SnAgCuEr Lead-free Solders Under High Temperature Aging显示文摘 | Hu Hao Yaowu Shi Zhidong Xia Yongping Lei Fu Guo | 2008 | Journal of Electronic Materials2008，，1： | 1 |
| 12 | <ce:link locator='fx1'/> Increased Regulatory T Cells Correlate With CD8 T-Cell Impairment and Poor Survival in Hepatocellular Carcinoma Patients显示文摘 | Junliang Fu Dongping Xu Zhenwen Liu Ming Shi Ping Zhao Baoyun Fu Zheng Zhang Huiyin Yang Hui Zhang Chunbao Zhou Jinxia Yao Lei Jin Huifen Wang Yongping Yang Yang-Xing Fu Fu-Sheng Wang | 2007 | Gastroenterology2007，，7： | 1 |
| 13 | Laser cladding in-situ NbC particle reinforced Fe-based composite coatings with rare earth oxide addition 显示文摘 | Qingtang Li Yongping Lei Hanguang Fu | 2014 | Surface and Coatings Technology2014，239，1： | 1 |
| 14 | Structural variations in heat treated B-bearing stainless steel 显示文摘 | Fu Hanguang Li Zhenhua Lei Yongping | 2009 | Materials and Design2009，30，3： | 1 |
| 15 | 查看详情显示文摘 | FU Yongping LI Yunde | | 0，，： | 1 |
| 16 | Effects of small amount addition of rare earth Er on microstructure and property of SnAgCu solder显示文摘 | Yaowu Shi Jun Tian Hu Hao Zhidong Xia Yongping Lei Fu Guo | 2007 | Journal of Alloys and Compounds2007，，1： | 1 |
| 17 | Effect of homogenization temperature on microstructure and mechanical properties of low-carbon high-boron cast steel显示文摘 | Fu Hanguang Song Xuding Lei Yongping | | 0，，03： | 1 |
| 18 | Functional impairment in circulating and intrahepatic NK cells and relative mechanism in hepatocellular carcinoma patients显示文摘 | Lun Cai Zheng Zhang Lin Zhou Haiyan Wang Junliang Fu Shuye Zhang Min Shi Hui Zhang Yongping Yang Hao Wu Po Tien Fu-Sheng Wang | 2008 | Clinical Immunology2008，，： | 1 |
| 19 | Production of large transverse momentum dileptons and photons in pp,dA,and AA col isions by photoproduction processes显示文摘 | Fu Yongping Li Yunde | | 0，，： | 1 |
| 20 | <ce:link locator='fx1'/> Increased Regulatory T Cells Correlate With CD8 T-Cell Impairment and Poor Survival in Hepatocellular Carcinoma Patients显示文摘 | Junliang Fu Dongping Xu Zhenwen Liu Ming Shi Ping Zhao Baoyun Fu Zheng Zhang Huiyin Yang Hui Zhang Chunbao Zhou Jinxia Yao Lei Jin Huifen Wang Yongping Yang Yang-Xing Fu Fu-Sheng Wang | 2007 | Gastroenterology2007，，7： | 1 |
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