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| 1 | Application of biomaterials for the repair and treatment of osteonecrosis of the femoral head显示文摘Osteonecrosis of the femoral head(ONFH)is one of the most common causes of hip disability in young adults.However,its cause and pathogenesis remain unclear,and might be caused by a variety of factors.ONFH mainly occurs in young adults.If not treated,70–80%of patients would progress into femoral head collapse in 3 years,and eventually require hip arthroplasty.Since these patients are younger and more physically active,multiple revision hip arthroplasty might be needed in their life.Repeated revision hip arthroplasty is difficult and risky,and has many complications,which inevitably affects the physical and mental health of patients.To delay the time of total hip arthroplasty for young adult patients with ONFH,biomaterials are used for its repair,which has a high clinical and social value for the retention of the patient’s own hip function.At present,there are many types of biomaterials used in repairing the femoral head,there is no uniform standard of use and the clinical effects are different.In this review,the main biomaterials used in the repair of ONFH are summarized and analyzed,and the prospects are also described. | Dewei Zhao Zhijie Ma | 2020 | Regenerative Biomaterials2020，7，1： | 8 |
| 2 | Materials evolution of bone plates for internal fixation of bone fractures:A review显示文摘Bone plates play a vital role in bone fracture healing by providing the necessary mechanical fixation for fracture fragments through modulating biomechanical microenvironment adjacent to the fracture site.Good treatment effect has been achieved for fixation of bone fracture with conventional bone plates,which are made of stainless steel or titanium alloy.However,several limitations still exist with traditional bone plates including loosening and stress shielding due to significant difference in modulus between metal material and bone tissue that impairs optimal fracture healing.Additionally,due to demographic changes and non-physiological loading,the population suffering from refractory fractures,such as osteoporosis fractures and comminuted fractures,is increasing,which imposes a big challenge to traditional bone plates developed for normal bone fracture repair.Therefore,optimal fracture treatment with adequate fixation implants in terms of materials and design relevant to special conditions is desirable.In this review,the complex physiological process of bone healing is introduced,followed by reviewing the development of implant design and biomaterials for bone plates.Finally,we discuss recent development of hybrid bone plates that contains bioactive elements or factors for fracture healing enhancement as a promising direction.This includes biodegradable Mg-based alloy used for designing bone screw-plates that has been proven to be beneficial for fracture healing,an innovative development that attracts more and more attention.This paper also indicates that the tantalum bone plates with porous structure are also emerging as a new fracture internal fixation implants.The reduction of the stress shielding is verified to be useful to accelerate bone fracture healing.Potential application of biodegradable metals may also avoid a second operation for implant removal.Further developments in biometals and their design for orthopedic bone plates are expected to improve the treatment of bone fracture,especially the refractory fractures. | Junlei Li Ling Qin Ke Yang Zhijie Ma Yongxuan Wang Liangliang Cheng Dewei Zhao | 2020 | Journal of Materials Science & Technology2020，36，1： | 5 |
| 3 | Decomposition and decoupling analysis of carbon dioxide emissions in African countries during 1984–2014显示文摘The potential for mitigating climate change is growing worldwide,with an increasing emphasis on reducing CO_(2)emissions and minimising the impact on the environment.African continent is faced with the unique challenge of climate change whilst coping with extreme poverty,explosive population growth and economic difficulties.CO_(2)emission patterns in Africa are analysed in this study to understand primary CO_(2)sources and underlying driving forces further.Data are examined using gravity model,logarithmic mean divisia index and Tapio's decoupling indicator of CO_(2)emissions from economic development in 20 selected African countries during 1984-2014.Results reveal that CO_(2)emissions increased by 2.11%(453.73 million ton)over the research period.Gravity centre for African CO_(2)emissions had shifted towards the northeast direction.Population and economic growth were primary driving forces of CO_(2)emissions.Industrial structure and emission efficiency effects partially offset the growth of CO_(2)emissions.The economic growth effect was an offset factor in central African countries and Zimbabwe due to political instability and economic mismanagement.Industrial structure and emission efficiency were insufficient to decouple economic development from CO_(2)emissions and relieve the pressure of population explosion on CO_(2)emissions in Africa.Thus,future efforts in reducing CO_(2)emissions should focus on scaleup energy-efficient technologies,renewable energy update,emission pricing and long-term green development towards sustainable development goals by 2030. | Claudien Habimana Simbi Jianyi Lin Dewei Yang Jean Claude Ndayishimiye Yang Liu Huimei Li Lingxing Xu Weijing Ma | 2021 | Journal of Environmental Sciences2021，33，4： | 3 |
| 4 | Porous silicon carbide coated with tantalum as potential material for bone implants显示文摘Porous silicon carbide(SiC)has a specific biomorphous microstructure similar to the trabecular microstructure of human bone.Compared with that of bioactive ceramics,such as calcium phosphate,SiC does not induce spontaneous interface bonding to living bone.In this study,bioactive tantalum(Ta)metal deposited on porous SiC scaffolds by chemical vapour deposition was investigated to accelerate osseointegration and improve the bonding to bones.Scanning electron microscopy indicated that the Ta coating evenly covered the entire scaffold structure.Energy-dispersive spectroscopy and X-ray diffraction analysis showed that the coating consisted of Ta phases.The bonding strength between the Ta coating and the SiC substrate is 88.4MPa.The yield strength of porous SiC with a Ta coating(pTa)was 45.862.9MPa,the compressive strength was 61.463.2MPa and the elasticmodulus was4.8GPa.When MG-63 human osteoblasts were co-cultured with pTa,osteoblasts showed good adhesion and spreading on the surface of the pTa and its porous structure,which showed that it has excellent bioactivity and cyto-compatibility.To further study the osseointegration properties of pTa.PTa and porous titanium(pTi)were implanted into the femoral neck of goats for 12weeks,respectively.The Van-Gieson staining of histological sections results that the pTa group had better osseointegration than the pTi group.These results indicate that coating bioactive Ta metal on porous SiC scaffolds could be a potential material for bone substitutes. | Zhijie Ma Jingyu Li Fang Cao Jiahui Yang Rong Liu Dewei Zhao | 2020 | Regenerative Biomaterials2020，7，5： | 3 |
| 5 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 6 | Single-crystal microplates of two-dimensional organic-inorganic lead halide layered perovskites for optoelectronics显示文摘器官无机的混合 perovskites 在高效率的太阳能电池和轻排放由于他们的应用吸引可观的注意。与三维的 perovskites 相比,二维(2D ) 分层的混合 perovskites 有一个更高的激子绑定精力和潜在地更高的轻排放的效率。因为他们能是为综合光电子的合适的积木,有明确的 nanoscale 形态学的高质量的水晶的 2D perovskites 的生长是合乎需要的并且(nano ) photonics。此处,我们基于 2-phenylethylammonium 报导 2D perovskites 的单个水晶的 microplates 的灵巧的答案生长( C 6 H 5 CH 2 CH 2 NH 3+,豌豆)阳离子,(豌豆) 2 PbX 4( X = Br ,我),与通过一个溶解再结晶过程的明确的矩形的几何学和 nanoscale 厚度。水晶结构(豌豆)2 PbX 4 首先用单个水晶的 X 光检查衍射被证实。一个答案阶段运输生长过程被开发在与与铅醋酸盐先锋电影涂的底层不同的另一干净底层上与几百纳米的十测微计和厚度的一种典型尺寸种 microplates。表面地形学分析建议 2D microplates 的形成被婚礼蛋糕生长机制多半驾驶。通过卤化物 alloying,光致发光排放(豌豆)2 Pb (Br,我) 有狭窄的山峰带宽的 4 perovskites 乐意地被调节从紫(~ 410 nm ) 到绿色(~ 530 nm ) 。 | Dewei Ma Yongping Fu Lianna Dang Jianyuan Zhai Ilia A. Guzei Song Jin | 2017 | Nano Research2017，10，6： | 2 |
| 7 | The dynamic response of vascular endothelial cells to fluidshear stress显示文摘 | Dewey CF Jr Bussolari SR Gimbrone MA Jr | 1981 | ASMEJ Bio Mech Eng1981，103，： | 1 |
| 8 | One-Year Follow-Up After Thoracoscopic Sympathectomy for Hyperhidrosis: Outcomes and Consequences显示文摘 | Dewey TM Herbert MA Hill SL etal | 2006 | Ann Thorac Surg2006，81，4： | 1 |
| 9 | The dynamic response of vascular endothelial cells to fluid shear stress 显示文摘 | Dewey CF Jr Bussolari SR Gimbrone MA | 1981 | Journal of Biomechanical Engineering1981，103，3： | 1 |
| 10 | Turbulent fluid shear mess induces vascular endothelial cell tumover in vitro 显示文摘 | Davies PF Renmzzi A Gordon EJ Dewey CF Jr Gimbrone MA Jr | 1986 | Proc Natl Acad Sci USA1986，83，7： | 1 |
| 11 | The dynamic response of vascular endothelial cells to fluid shear stress显示文摘 | Dewey CF Jr Bussolari SR Gimbrone MA Jr | 1981 | J Biomech Eng1981，103，： | 1 |
| 12 | Fabrication and plasma resistance properties of transparent YAG ceramics显示文摘 | Xianpeng Qin Guohong Zhou Hao Yang Jen It Wong Jian Zhang Dewei Luo Shiwei Wang Jan Ma Dingyuan Tang | 2011 | Ceramics International2011，，3： | 1 |
| 13 | One-year follow-up after thoracoscopic sympathectomy for hyperhidrosis: outcomes and consequences显示文摘 | Dewey TM Herbert MA Hill SL | 2006 | Ann Thorac Surg2006，81，4： | 1 |
| 14 | Fabrication and laser properties of transparent Yb:YAG ceramics显示文摘 | Dewei Luo Jian Zhang Changwen Xu Xianpeng Qin Dingyuan Tang Jan Ma | 2011 | Optical Materials2011，，6： | 1 |
| 15 | Fabrication and properties of highly transparent Er:YAG ceramics显示文摘 | Xianpeng Qin Hao Yang Guohong Zhou Dewei Luo Yan Yang Jian Zhang Shiwei Wang Jan Ma Dingyuan Tang | 2011 | Optical Materials2011，，6： | 1 |
| 16 | Synthesis of submicron-sized spherical Y 2 O 3 powder for transparent YAG ceramics显示文摘 | Xianpeng Qin Hao Yang Guohong Zhou Dewei Luo Jian Zhang Shiwei Wang Jan Ma | 2010 | Materials Research Bulletin2010，，2： | 1 |
| 17 | Vascular endothelial cells respond to spatial gradients in fluid shear stress by enhanced activation of transcription factors显示文摘 | Nagel T Resnick N Dewey CF Gimbrone MA | 1999 | Arterioscler Thromb Vasc Biol1999，19，8： | 1 |
| 18 | The dynamic response of vascular endothelial cells to fluid shear stress 显示文摘 | Dewey CF Jr Bussolari SR Gimbrone MA Jr | 1981 | J Biomech Eng1981，103，： | 1 |
| 19 | Experimental study of a 3D printed permanent implantable porous Ta-coated bone plate for fracture fixation显示文摘Metal plates have always been the gold standard in the clinic for internal fracture fixation due to their high strength advantages.However,high elastic modulus can cause stress shielding and lead to bone embrittlement.This study used an electron beam melting method to prepare personalized porous Ti6Al4V(pTi)bone plates.Then,chemical vapor deposition(CVD)technology coats tantalum(Ta)metal on the pTi bone plates.The prepared porous Ta-coated bone plate has an elastic modulus similar to cortical bone,and no stress shielding occurred.In vitro experiments showed that compared with pTi plates,Ta coating significantly enhances the attachment and proliferation of cells on the surface of the scaffold.To better evaluate the function of the Ta-coated bone plate,animal experiments were conducted using a coat tibia fracture model.Our results showed that the Ta-coated bone plate could effectively fix the fracture.Both imaging and histological analysis showed that the Ta-coated bone plate had prominent indirect binding of callus formation.Histological results showed that new bone grew at the interface and formed good osseointegration with the host bone.Therefore,this study provides an alternative to bio-functional Ta-coated bone plates with improved osseointegration and osteogenic functions for orthopaedic applications. | Baoyi Liu Zhijie Ma Junlei Li Hui Xie Xiaowei Wei Benjie Wang Simiao Tian Jiahui Yang Lei Yang Liangliang Cheng Lu Li Dewei Zhao | 2022 | Bioactive Materials2022，7，4： | 0 |
| 20 | Unraveling the Effect of Stacking Configurations on Charge Transfer in WS_(2) and Organic Semiconductor Heterojunctions显示文摘Photoinduced interfacial charge transfer plays a critical role in energy conversion involving van der Waals(vdW)heterostructures constructed of inorganic nanostructures and organic materials.However,the effect of molecular stacking configurations on charge transfer dynamics is less understood.In this study,we demonstrated the tunability of interfacial charge separation in a type-Ⅱ heterojunction between monolayer(ML)WS_(2) and an organic semiconducting molecule[2-(3″′,4′-dimethyl-[2,2′:5′,2′:5″,2″′-quaterthiophen]-5-yl)ethan-1-ammonium halide(4Tm)]by rational design of relative stacking configurations.The assembly between ML-WS_(2) and the 4Tm molecule forms a face-to-face stacking when 4Tm molecules are in a selfaggregation state.In contrast,a face-to-edge stacking is observed when 4Tm molecule is incorporated into a 2D organic-inorganic hybrid perovskite lattice.The face-to-face stacking was proved to be more favorable for hole transfer from WS_(2) to 4Tm and led to interlayer excitons(IEs)emission.Transient absorption measurements show that the hole transfer occurs on a time scale of 150 fs.On the other hand,the face-to-edge stacking resulted in much slower hole transfer without formation of IEs.This inefficient hole transfer occurs on a similar time scale as A exciton recombination in WS_(2),leading to the formation of negative trions.These investigations offer important fundamental insights into the charge transfer processes at organic−inorganic interfaces. | Shuchen Zhang Dewei Sun Jiaonan Sun Ke Ma Zitang Wei Jee Yung Park Aidan H.Coffey Chenhui Zhu Letian Dou Libai Huang | 2023 | Precision Chemistry2023，1，7： | 0 |
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