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| 1 | Simplified criteria for diagnosing superficial esophageal squamous neoplasms using Narrow Band Imaging magnifying endoscopy显示文摘AIM To simplify the diagnostic criteria for superficial esophageal squamous cell carcinoma(SESCC) on Narrow Band Imaging combined with magnifying endoscopy(NBI-ME).METHODS This study was based on the post-hoc analysis of a randomized controlled trial. We performed NBI-ME for 147 patients with present or a history of squamous cell carcinoma in the head and neck, or esophagus between January 2009 and June 2011. Two expert endoscopistsdetected 89 lesions that were suspicious for SESCC lesions, which had been prospectively evaluated for the following 6 NBI-ME findings in real time: 'intervascular background coloration'; 'proliferation of intrapapillary capillary loops(IPCL)'; and 'dilation', 'tortuosity', 'change in caliber', and 'various shapes(VS)' of IPCLs(i.e., Inoue's tetrad criteria). The histologic examination of specimens was defined as the gold standard for diagnosis. A stepwise logistic regression analysis was used to identify candidates for the simplified criteria from among the 6 NBI-ME findings for diagnosing SESCCs. We evaluated diagnostic performance of the simplified criteria compared with that of Inoue's criteria.RESULTS Fifty-four lesions(65%) were histologically diagnosed as SESCCs and the others as low-grade intraepithelial neoplasia or inflammation. In the univariate analysis, proliferation, tortuosity, change in caliber, and VS were significantly associated with SESCC(P < 0.01). The combination of VS and proliferation was statistically extracted from the 6 NBI-ME findings by using the stepwise logistic regression model. We defined the combination of VS and proliferation as simplified dyad criteria for SESCC. The areas under the curve of the simplified dyad criteria and Inoue's tetrad criteria were 0.70 and 0.73, respectively. No significant difference was shown between them. The sensitivity, specificity, and accuracy of diagnosis for SESCC were 77.8%, 57.1%, 69.7% and 51.9%, 80.0%, 62.9% for the simplified dyad criteria and Inoue's tetrad criteria, respectively.CONCLUSION The combination of proliferation and VS may serve as simplified criteria for the diagnosis of SESCC using NBIME. | Akira Dobashi Kenichi Goda Noboru Yoshimura Tomohiko R Ohya Masayuki Kato Kazuki Sumiyama Masato Matsushima Shinichi Hirooka Masahiro Ikegami Hisao Tajiri | 2016 | World Journal of Gastroenterology2016,22,41: | 10 |
| 2 | Diagnostic utility of narrow-band imaging endoscopy for pharyngeal superfi cial carcinoma显示文摘AIM: To investigate the endoscopic features of pharyngeal superfi cial carcinoma and evaluate the utility of narrow-band imaging (NBI) for this disease. METHODS: In the present prospective study, 335 patients underwent conventional white light (CWL) en-doscopy and non-magnifi ed/magnifi ed NBI endoscopy, followed by an endoscopic biopsy, for 445 superfi cial lesions in the oropharynx and hypopharynx. The macroscopic appearance of superfi cial lesions was categorized as either elevated (< 5 mm in height), flat, or depressed (not ulcerous). Superficial carcinoma (SC) was defi ned as a superfi cial lesion showing high-grade dysplasia or squamous cell carcinoma on histology. The color, delineation, and macroscopic appearances of the lesions were evaluated by CWL endoscopy. The ratio of the brownish area/intervascular brownish epithelium (IBE), as well as microvascular proliferation, dilation, and irregularities, was determined by non-magnifi ed/ magnifi ed NBI endoscopy. An experienced pathologist who was unaware of the endoscopic fi ndings made the histological diagnoses. By comparing endoscopic fi ndings with histology, we determined the endoscopic features of SC and evaluated the diagnostic utility of NBI. RESULTS: The 445 lesions were divided histologically into two groups: a non-SC group, including non-neoplasia and low-grade dysplasia cases, and an SC group. Of the 445 lesions examined, 333 were classified as non-SC and 112 were classif ied as SC. There were no significant differences in age, gender, or the location of the lesions between the patients in the two groups. The mean diameter of the SC lesions was signif icantly greater than that of non-SC lesions (11.0 ± 7.6 mm vs 4.6 ± 3.6 mm, respectively, P < 0.001). Comparisons of CWL endoscopy fi ndings for SC and non-SC lesions by univariate analysis revealed that the incidence of redness (72% vs 41%, respectively, P < 0.001) and a flat or depressed type of lesion (58% vs 44%, respectively, P = 0.013) was significantly higher in the SC group. Using non-magnifi ed NBI endoscopy, the incidence of a brownish area was signifi cantly higher for SC lesions (79% vs 57%, respectively, P < 0.001). On magnifi ed NBI endoscopy, the incidence of IBE (68% vs 33%, P < 0.001) and microvascular proliferation (82% vs 51%, P < 0.001), dilation (90% vs 76%, P =0.002), and irregularity (82% vs 31%, P < 0.001) was also signifi cantly higher for the SC compared with the non-SC lesions. Multivariate analysis revealed that the incidence of redness (P = 0.022) on CWL endoscopy and IBE (P < 0.001) and microvascular irregularities (P < 0.001) on magnif ied NBI endoscopy was signif icantly higher in SC than non-SC lesions. Redness alone exhibited signifi cantly higher sensitivity and signifi cantly lower specifi city for the diagnosis of SC compared with redness plus IBE and microvascular irregularities (72% vs 52%, P = 0.002; and 59% vs 92%, P < 0.001, respectively). The accuracy of redness plus IBE and irregularities for the diagnosis of SC was signifi cantly greater than using redness alone (82% vs 62%, respectively, P < 0.001). CONCLUSION: Redness, IBE, and microvascular irregularities appear to be closely related to SC lesions. Magnifi ed NBI endoscopy may increase the diagnostic accuracy of CWL endoscopy for SC. | Noboru Yoshimura Kenichi Goda Hisao Tajiri Yukinaga Yoshida Takakuni Kato Yoichi Seino Masahiro Ikegami Mitsuyoshi Urashima | 2011 | World Journal of Gastroenterology2011,17,45: | 7 |
| 3 | Protocol for laparoscopic cholecystectomy: Is it rocket science?显示文摘Laparoscopic cholecystectomy(LC) does not require advanced techniques, and its performance has therefore rapidly spread worldwide. However, the rate of biliary injuries has not decreased. The concept of the critical view of safety(CVS) was first documented two decades ago. Unexpected injuries are principally due to misidentification of human factors. The surgeon's assumption is a major cause of misidentification, and a high level of experience alone is not sufficient for successful LC. We herein describe tips and pitfalls of LC in detail and discuss various technical considerations.Finally, based on a review of important papers and our own experience, we summarize the following mandatory protocol for safe LC:(1) consideration that a high level of experience alone is not enough;(2) recognition of the plateau involving the common hepatic duct and hepatic hilum;(3) blunt dissection until CVS exposure;(4) Calot's triangle clearance in the overhead view;(5) Calot's triangle clearance in the view from underneath;(6) dissection of the posterior right side of Calot's triangle;(7) removal of the gallbladder body; and(8) positive CVS exposure. We believe that adherence to this protocol will ensure successful and beneficial LC worldwide, even in patients with inflammatory changes and rare anatomies. | Tomohide Hori Fumitaka Oike Hiroaki Furuyama Takafumi Machimoto Yoshio Kadokawa Toshiyuki Hata Shigeru Kato Daiki Yasukawa Yuki Aisu Maho Sasaki Yusuke Kimura Yuichiro Takamatsu Masato Naito Masaya Nakauchi Takahiro Tanaka Daigo Gunji Kiyokuni Nakamura Kiyoko Sato Masahiro Mizuno Taku Iida Shintaro Yagi Shinji Uemoto Tsunehiro Yoshimura | 2016 | World Journal of Gastroenterology2016,22,47: | 3 |
| 4 | Bevacizumab plus chemotherapy for advanced non-squamous non-small-cell lung cancer with malignant pleural effusion显示文摘 | Kazuhiro Kitamura Kaoru Kubota Masahiro Ando Satoshi Takahashi Nobuhiko Nishijima Teppei Sugano Masaru Toyokawa Koji Miwa Seiji Kosaihira Rintaro Noro Yuji Minegishi Masahiro Seike Akinobu Yoshimura Akihiko Gemma | 2013 | Cancer Chemotherapy and Pharmacology2013,,2: | 2 |
| 5 | Features and Function of Multiple Evanescent White Dot Syndrome显示文摘 | Hanga I M Masahiro Fujimoto M Yoshimura N | 2009 | Arch Ophthalmol2009,127,10: | 1 |
| 6 | 显示文摘 | Hideo Toraya Masahiro Yoshimura Shigeyuki Somiya | 1982 | Journal of the American Ceramic Society1982,65,5: | 1 |
| 7 | Pulmonary atresia with intact ventricular septum: Strategy based on right ventricular morphology显示文摘 | Naoki Yoshimura Masahiro Yamaguchi Hidetaka Ohashi Yoshihiro Oshima Shigeteru Oka Masahiro Yoshida Hirohisa Murakami Teruo Tei | 2003 | The Journal of Thoracic and Cardiovascular Surgery2003,,5: | 1 |
| 8 | Importance of soft solution processing for advanced inorganic materials显示文摘 | Masahiro Yoshimura | 1998 | J Mater Res1998,13,4: | 1 |
| 9 | Radiofrequency catheter ablation of premature ventricular complexes from right ventricular outflow tract improves left ventricular dilation and clinical status in patients without structural heart disease显示文摘 | Masao Takemoto Hitoshi Yoshimura Yurika Ohba Yasuharu Matsumoto Umpei Yamamoto Masahiro Mohri Hideo Yamamoto Hideki Origuchi | 2005 | Journal of the American College of Cardiology2005,,8: | 1 |
| 10 | Metastable- stable phase diagrams in the zirconia- containing systems utilized in solid - oxide fuel cell application 显示文摘 | Masatomo Yashima Masato Kakihana Masahiro Yoshimura | 1996 | Solid State Ionics1996,8688,: | 1 |
| 11 | What, how, and why soft and solution processing for advanced inorganic materials显示文摘 | Masahiro Yoshimura | 1997 | Key Engineering Materials1997,,132136: | 1 |
| 12 | Importance of soft solution processing for advanced inorganic materials显示文摘 | Masahiro Yoshimura | 1998 | J Mater Res1998,13,4: | 1 |
| 13 | Calibration Curve for Quantitative Analysis of the Monoclinic-Tetragonal ZrO2 System by X-Ray Dffraction显示文摘 | Hideo Toraya Masahiro Yoshimura Skigeyuki Somiya | 1984 | J Am Ceram Soc1984,67,6: | 1 |
| 14 | Boron nitride synthesized at ambient pressure and room temperature by plasma electrolysis显示文摘 | Jing Guo Hao Wang JingSen Zhu Kun Zheng ManKang Zhu Hui Yan Masahiro Yoshimura | 2007 | Electrochemistry Communications2007,,7: | 1 |
| 15 | Metastable-stable phase diagrams in the zirconia-containing systems utilized in solid-oxide fuel cell application显示文摘 | Masatomo Yashima Masato Kakihana Masahiro Yoshimura | 1996 | Solid State Ionics1996,8688,: | 1 |
| 16 | Electrical properties of BaTiO3 thin film grown by the hydrothermal-electrochemical method 显示文摘 | KOJI KAJIYOSHI YUKIO SAKABE MASAHIRO YOSHIMURA | 1997 | Japanese Journal of Applied Physics1997,36,: | 1 |
| 17 | Surface active N-acylglutamate:preparation of long chain N-acylglutamic acid显示文摘 | MASAHIRO T YOSHIMURA I TAKIZAWA K | 1972 | Journal of the American Oil Chemists'' Society1972,49,3: | 1 |
| 18 | Processing and properties of hydroxyapatite-based biomaterials for use as hard tissue replacement implants显示文摘 | Masahiro Yoshimura | 1998 | J Mater Res1998,13,1: | 1 |
| 19 | Importance of soft solution processing for advanced inorganic materials显示文摘 | Masahiro Yoshimura | 1998 | Journal of Materials Research1998,,4: | 1 |
| 20 | 显示文摘 | Yoshimura Masahiro Ohmura Mitsuhiro Cho Woo-Seok | 1997 | J Am Ceram Soc1997,80,9: | 1 |