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| 1 | Radiotherapy as valid modality for hepatocellular carcinoma with portal vein tumor thrombosis显示文摘Although the current standard treatment for hepatocellular carcinoma(HCC) with portal vein tumor thrombosis(PVTT) is sorafenib, many previous studies have established the need for a reliable local modality for PVTT control, which is a major cause of liver function deterioration and metastasis. Additionally, there is growing evidence for the prognostic significance of PVTT classification according to the location of tumor thrombosis. Favorable outcomes can be obtained by applying local modalities, including surgery or transarterial chemoembolization, especially in second-order or distal branch PVTT. Rapid control of PVTT could maintain or improve liver function and reduce intrahepatic as well as distant metastasis. Radiotherapy(RT) is one of the main locoregional treatment modalities in oncologic fields, but has rarely been used in HCC because of concerns regarding hepatic toxicity. However, with the development of advanced techniques, RT has been increasingly applied in HCC management. Randomized studies have yet to definitively prove the benefit of RT, but several comparative studies have justified the application of RT in HCC. The value of RT is especially noticeable in HCC with PVTT; several prospective and retrospective studies have reported favorable outcomes, including a 40% to 60% objective response rate and median overall survival of 15 mo to 20 mo in responders. In this review, we evaluate the role of RT as an alternative local modality in HCC with PVTT. | Jeong Il Yu Hee Chul Park | 2016 | World Journal of Gastroenterology2016,22,30: | 20 |
| 2 | Anemia after gastrectomy for early gastric cancer:Long-term follow-up observational study显示文摘AIM:To identify the incidence and etiology of anemia after gastrectomy in patients with long-term follow-up after gastrectomy for early gastric cancer.METHODS:The medical records of those patients with early gastric adenocarcinoma who underwent curative gastrectomy between January 2006 and October 2007 were reviewed.Patients with anemia in the preoperative workup,cancer recurrence,undergoing systemic chemotherapy,with other medical conditions that can cause anemia,or treated during follow up with red cell transfusions or supplements for anemia were excluded.Anemia was defined by World Health Organization criteria(Hb < 12 g/dL in women and < 13 g/dL in men).Iron deficiency was defined as serum ferritin < 20 g/dL.Vitamin B12 deficiency was defined as serum vitamin B 12 < 200 pg/mL.Iron deficiency anemia was defined as anemia with concomitant iron deficiency.Anemia from vitamin B 12 deficiency was defined as megaloblastic anemia(mean cell volume > 100 fL) with vitamin B 12 deficiency.The profile of anemia over 48 mo of follow-up was analyzed.RESULTS:One hundred sixty-one patients with gastrectomy for early gastric cancer were analyzed.The incidence of anemia was 24.5% at 3 mo after surgery and increased up to 37.1% at 48 mo after surgery.The incidence of iron deficiency anemia increased during the follow up and became the major cause of anemia at 48 mo after surgery.Anemia of chronic disease and megaloblastic anemia were uncommon.The incidence of anemia in female patients was significantly higher than in male patients at 12(40.0% vs 22.0%,P = 0.033),24(45.0% vs 25.0%,P = 0.023),36(55.0% vs 28.0%,P = 0.004),and 48 mo(52.0% vs 31.0%,P = 0.022) after surgery.Patients with total gastrectomy showed significantly higher incidence of anemia than patients with subtotal gastrectomy at 48 mo after surgery(60.7% vs 31.3%,P = 0.008).The incidence of iron deficiency was significantly higher in female patients than in male patients at 6(35.4% vs 13.3%,P = 0.002),12(45.8% vs 16.8%,P < 0.001),18(52.1% vs 22.3%,P < 0.001),24(60.4% vs 20.9%,P < 0.001),36(62.5% vs 29.2%,P < 0.001),and 48 mo(66.7% vs 34.7%,P = 0.001) after surgery.CONCLUSION:Anemia was frequent after gastrectomy for early gastric cancer,with iron deficiency being the major cause.Evaluation for anemia including iron status should be performed after gastrectomy and appropriate iron replacement should be considered. | Chul-Hyun Lim Sang Woo Kim Won Chul Kim Jin Soo Kim Yu Kyung Cho Jae Myung Park In Seok Lee Myung-Gyu Choi Kyo-Young Song Hae Myung Jeon Cho-Hyun Park | 2012 | World Journal of Gastroenterology2012,18,42: | 18 |
| 3 | Proton therapy for hepatocellular carcinoma:Current knowledges and future perspectives显示文摘Hepatocellular carcinoma(HCC) is the second leading cause of cancer-related death, as few patients can be treated with currently available curative local modalities. In patients with HCC where curative modalities are not feasible, radiation therapy(RT) has emerged as an alternative or combination therapy. With the development of various technologies, RT has been increasingly used for the management of HCC. Among these advances, proton beam therapy(PBT) has several unique physical properties that give it a finite range in a distal direction, and thus no exit dose along the beam path. Therefore, PBT has dosimetric advantages compared with X-ray therapy for the treatment of HCC. Indeed, various reports in the literature have described the favorable clinical outcomes and improved safety of PBT for HCC patients compared with X-ray therapy. However, there are some technical issues regarding the use of PBT in HCC, including uncertainty of organ motion and inaccuracy during calculation of tissue density and beam range, all of which may reduce the robustness of a PBT treatment plan. In this review, we discuss the physical properties, current clinical data, technical issues, and future perspectives on PBT for the treatment of HCC. | Gyu Sang Yoo Jeong Il Yu Hee Chul Park | 2018 | World Journal of Gastroenterology2018,24,28: | 8 |
| 4 | The feasibility of combined transcatheter arterial chemoembolization and radiotherapy for advanced hepatocellular carcinoma显示文摘 | Ju‐Yeon Cho Yong‐Han Paik Hee Chul Park Jeong Il Yu Won Sohn Geum‐Youn Gwak Moon Seok Choi Joon Hyeok Lee Kwang Cheol Koh Seung Woon Paik Byung Chul Yoo | 2014 | Liver Int2014,,5: | 5 |
| 5 | Effect of Helicobacter pylori Eradication on Metachronous Gastric Cancer after Endoscopic Resection of Gastric Tumors: A Meta‐Analysis显示文摘 | Seung Bae Yoon Jae Myung Park Chul‐Hyun Lim Yu Kyung Cho Myung‐Gyu Choi | 2014 | Helicobacter2014,,4: | 3 |
| 6 | Ischemic colitis secondary to inferior mesenteric arteriovenous fistula and portal vein stenosis in a liver transplant recipient显示文摘Arteriovenous fistula (AVF) involving the inferior mesenteric vessels is rare, and the affected patients usually present with abdominal pain, mass, or features of established portal hypertension. Colonic ischemia is a less common and more serious manifestation of AVF. We report a case of ischemic colitis secondary to inferior mesenteric AVF in a patient who underwent a previous liver transplantation, subsequently developed portal vein stenosis, and then presented with acute lower gastrointestinal bleeding. He underwent percutaneous transhepatic placement of a portal vein stent and left colectomy. | In Hee Kim Dae Ghon Kim Hyo Sung Kwak Hee Chul Yu Baik Hwan Cho Ho Sung Park | 2008 | World Journal of Gastroenterology2008,14,26: | 2 |
| 7 | A Prospective Randomized Controlled Study Comparing Outcomes of Standard Resection and Extended Resection, Including Dissection of the Nerve Plexus and Various Lymph Nodes, in Patients With Pancreatic Head Cancer显示文摘 | Jin-Young Jang Mee Joo Kang Jin Seok Heo Seong Ho Choi Dong Wook Choi Sang Jae Park Sung-Sik Han Dong Sup Yoon Hee Chul Yu Koo Jeong Kang Sang Geol Kim Sun-Whe Kim | 2014 | Annals of Surgery2014,,4: | 2 |
| 8 | Predictive factors for local recurrence after endoscopic resection for early gastric cancer: long-term clinical outcome in a single-center experience显示文摘 | Jun Chul Park Sang Kil Lee Ju Hee Seo Yu Jin Kim Hyunsoo Chung Sung Kwan Shin Yong Chan Lee | 2010 | Surgical Endoscopy2010,,11: | 2 |
| 9 | Usefulness of continuous renal replacement therapy for correcting hypernatremia in a patient with severe congestive heart failure显示文摘 | Hoon Suk Park Yu Ah Hong Hyun Gyung Kim Sun Ryoung Choi In O. Sun Byung Ha Chung Cheol Whee Park Chul Woo Yang Yong Soo Kim Bum Soon Choi | 2012 | Hemodial Int2012,,4: | 1 |
| 10 | Implementation of a bandwidth allocation scheme in a token-passing fieldbus network 显示文摘 | Hong Seong Park Yu Chul Kim | 2002 | IEEE Trans on Instrumentation and Measurement2002,51,2: | 1 |
| 11 | Epoxication of styrene catalyzed by Ni(Ⅱ)-and Cu(Ⅱ)- macro cyclic complexes显示文摘 | Yu Chul Park Seong Su Kim | 1992 | Bulletin of the Korean Chemical Society1992,13,5: | 1 |
| 12 | Effect of Mosapride Combined with Esomeprazole Improves Esophageal Peristaltic Function in Patients with Gastroesophageal Reflux Disease: A Study Using High Resolution Manometry显示文摘 | Yu Kyung Cho Myung-Gyu Choi Eun Young Park Chul Hyun Lim Jin Su Kim Jae Myung Park In Seok Lee Sang Woo Kim Kyu Yong Choi | 2013 | Digestive Diseases and Sciences2013,,4: | 1 |
| 13 | Prognostic index for vein tumor thrombosis in patients with hepatocellular carcinoma treat with radiation therapy显示文摘 | Jeong ll Yu Hee Chul Park | 2011 | Korean Med Sci2011,26,: | 1 |
| 14 | Clinicopathological Features and Prognostic Factors of Proximal Gastric Carcinoma in a Population with High Helicobacter pylori Prevalence: A Single-Center, Large-Volume Study in Korea显示文摘 | Jun Chul Park MD Yong Chan Lee MD Jie-Hyun Kim MD Yu Jin Kim MD Sang Kil Lee MD Sung Kwan Shin MD Woo Jin Hyung MD Sung Hoon Noh MD Choong Bai Kim MD | 2010 | Annals of Surgical Oncology2010,,3: | 1 |
| 15 | Clinical impact of combined transarterial chemoembolization and radiotherapy for advanced hepatocellular carcinoma with portal vein tumor thrombosis: An external validation study显示文摘 | Jeong Il Yu Jae Won Park Hee Chul Park Sang Min Yoon Do Hoon Lim Joon Hyeok Lee Han Chu Lee Seon Woo Kim Jong Hoon Kim | 2015 | Radiotherapy and Oncology2015,,: | 1 |
| 16 | Bandwidth allocation scheme in CAN protocol显示文摘 | Hong Seong Park Yu Chul Kim | 2000 | IEEE Proc Control Theory and Applications2000,147,1: | 1 |
| 17 | Implementation of a bandwidth allocation scheme in a token-passing fieldbus network 显示文摘 | Hong Seong Park Yu Chul Kim | 2002 | IEEE Trans on Instrumentation and Measurement2002,51,2: | 1 |
| 18 | Upper normal threshold of serum alanine aminotransferase in identifying individuals at risk for chronic liver disease显示文摘 | Ha Na Park Dong Hyun Sinn Geum‐Youn Gwak Jee Eun Kim Sang Youl Rhee Sung June Eo Yu Jin Kim Moon Seok Choi Joon Hyeok Lee Kwang Cheol Koh Seung Woon Paik Byung Chul Yoo | 2012 | Liver Int2012,,6: | 1 |
| 19 | Effect of Mosapride Combined with Esomeprazole Improves Esophageal Peristaltic Function in Patients with Gastroesophageal Reflux Disease: A Study Using High Resolution Manometry显示文摘 | Yu Kyung Cho Myung-Gyu Choi Eun Young Park Chul Hyun Lim Jin Su Kim Jae Myung Park In Seok Lee Sang Woo Kim Kyu Yong Choi | 2013 | Digestive Diseases and Sciences2013,,4: | 1 |
| 20 | Predictive factors for local recurrence after endoscopic resection for early gastric cancer: long-term clinical outcome in a single-center experience显示文摘 | Jun Chul Park Sang Kil Lee Ju Hee Seo Yu Jin Kim Hyunsoo Chung Sung Kwan Shin Yong Chan Lee | 2010 | Surgical Endoscopy2010,,11: | 1 |