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| 1 | miR‐145 sensitizes ovarian cancer cells to paclitaxel by targeting Sp1 and Cdk6显示文摘 | Xiaolan Zhu Yuefeng Li Chanjuan Xie Xinming Yin Yueqin Liu Yuan Cao Yue Fang Xin Lin Yao Xu Wenlin Xu Huiling Shen Jian Wen | 2014 | Int. J. Cancer2014，，： | 2 |
| 2 | Effect of reforestation on annual water yield in a large watershed in northeast China显示文摘A simplified water balance model in conjunction with an evapotranspiration(ET) model and cumulative forest cover data were used to quantify the changes in annual water yield in response to reforestation in a large watershed, northeast China. Cumulative forest cover increased by 22 %, leading to a significant decrease in estimated annual water yield. Reforestation increased ET(P = 0.0144), resulting in a remarkable decrease(P = 0.0001) in estimated annual water yield according to the water balance model. Reforestation increased ET by33 mm and decreased annual water yield by 38 mm per decade. The effect of reforestation on annual water yield can be quantified using a simplified water balance model in a large watershed, although our reforestation area was small(about 20 %) in relation to the total watershed area. | Yuefeng Yao Tijiu Cai Cunyong Ju Chengxin He | 2015 | Journal of Forestry Research2015，26，3： | 2 |
| 3 | Electrolyte design for rechargeable anion shuttle batteries显示文摘As an emerging new type of battery chemistry,the anion shuttle battery(ASB),based on the shuttling and storage of anions,is considered a sustainable alternative to gigawatt-scale energy storage due to the associated resource abundance,low cost,high safety,and high energy density.Although significant progress has been achieved,practical applications of ASBs are still hindered by tough challenges,such as short lifetime,limited reversible capacity,and low Coulombic efficiency.Therefore,it is very necessary to design and explore new electrolyte systems with high electrochemical/chemical stability,sufficient compatibility towards electrodes,and excellent kinetics/reversibility for anion electrochemical reactions.Here,we review the recent achievements and main challenges in developing electrolytes for ASBs,which include solid,non-aqueous,and aqueous electrolytes.We mainly focus on the unique properties and basic principles of designing these electrolytes,and their various performance parameters.Perspectives on design strategies for ASB electrolytes are also presented,which could facilitate the development of advanced ASBs for grid-scale energy storage. | Yao Wang Xu Yang Zhijia Zhang Xia Hu Yuefeng Meng Xia Wang Dong Zhou Hao Liu Baohua Li Guoxiu Wang | 2022 | eScience2022，2，6： | 0 |
| 4 | Elimination of an unfavorable allele conferring pod shattering in an elite soybean cultivar by CRISPR/Cas9显示文摘Pod shattering can lead to devastating yield loss of soybean and has been a negatively selected trait in soybean domestication and breeding.Nevertheless,a significant portion of soybean cultivars are still pod shattering-susceptible,limiting their regional and climatic adaptabilities.Here we performed genetic diagnosis on the shattering-susceptible trait of a national registered cultivar,Huachun6(HC6),and found that HC6 carries the susceptible genotype of a candidate Pod dehiscence 1(PDH1)gene,which exists in a significant portion of soybean cultivars.We next performed genome editing on PDH1 gene by clustered regularly interspaced short palindromic repeats(CRISPR)-CRISPR-associated protein 9(Cas9).In T2 progenies,several transgene-free lines with pdh1 mutations were characterized without affecting major agronomic traits.The pdh1 mutation significantly improved the pod shattering resistance which is associated with aberrant lignin distribution in inner sclerenchyma.Our work demonstrated that precision breeding by genome editing on PDH1 holds great potential for precisely improving pod shattering resistance and adaptability of soybean cultivars. | Zhihui Zhang Jie Wang Huaqin Kuang Zhihong Hou Pingping Gong Mengyan Bai Shaodong Zhou Xiaolei Yao Shikui Song Long Yan Yuefeng Guan | 2022 | aBIOTECH2022，3，2： | 0 |
| 5 | Dt1 inhibits SWEET-mediated sucrose transport to regulate photoperiod-dependent seed weight in soybean显示文摘Soybean is a photoperiod-sensitive short-day crop whose reproductive period and yield are markedly affected by day-length changes.Seed weight is one of the key traits determining the soybean yield;how-ever,the prominent genes that control the final seed weight of soybean and the mechanisms underlying the photoperiod's effect on this trait remain poorly understood.In this study,we identify SwW19 as a major locus controlling soybean seed weight by QTL mapping and determine Dt1,an orthologous gene of Arabidopsis TFL1 that is known to govern the soybean growth habit,as the causal gene of the SW19 locus.We showed that Dt1 is highly expressed in developing seeds and regulates photoperiod-dependent seed weight in soybean.Further analyses revealed that the Dt1 protein physically interacts with the sucrose transporter GmSWEET10a to negatively regulate the import of sucrose from seed coat to the embryo,thus modulating seed weight under long days.However,Dt1 does not function in seed development under short days due to its very low expression.Importantly,we discovered a novel natural allelic variant of Dt1(H4 haplotype)that decouples its pleiotropic effects on seed size and growth habit;i.e.,this variant remains functional in seed development but fails to regulate the stem growth habit of soybean.Collectively,our findings provide new insights into how soybean seed development responds to photoperiod at different latitudes,offering an ideal genetic component for improving soybean's yield by manipulating its seed weightandgrowth habit. | Xiaoming Li Zhonghui Chen Haiyang Li Lin Yue Cuirong Tan Hongjie Liu Yilong Hu Yuhua Yang Xiani Yao Lingping Kong Xiang Huangi Bin Yu Chunyu Zhang Yuefeng Guan Baohui Liu Fanjiang Kong Xingliang Hou | 2024 | Molecular Plant2024，17，3： | 0 |
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