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| 1 | XPS study of potassium-promoted molybdenum carbides for mixed alcohols synthesis via CO hydrogenation显示文摘The X-ray photoelectron spectroscopy (XPS) was used to investigate the surface characteristic of potassium-promoted or un-promoted both β-Mo2C and α-MoC1-x pretreated by syngas at different temperatures,and the promotional effect of potassium on the catalytic performance was also studied.XPS results revealed that the content of surface Mo and its valence distribution between β-Mo2C and α-MoC1-x were quite different.Promoted by potassium,the remarkable changes were observed for surface composition and valence of Mo distribution over β-Mo2C.Potassium had strong electronic effect on β-Mo2C,which led to a higher Mo4+ content.On the contrary,potassium had little electronic effect on α-MoC1-x,and K-Mo interaction was weak.Therefore,Mo0 and Mo2+ became the dominant species on the catalyst surface,and the Mo4+ content showed almost no increase as the pretreatment temperature enhanced.In terms of catalytic performance of molybdenum carbides,the increase in Mo0 most likely explained the increase in hydrocarbon selectivity,yet Mo4+ might be responsible for the alcohols synthesis. | Minglin Xiang Debao Li Juan Zou Wenhuai Li Yuhan Sun Xichun She | 2010 | Journal of Natural Gas Chemistry2010，19，2： | 3 |
| 2 | Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function显示文摘The AMP-activated protein kinase(AMPK)is a central regulator of energy homeostasis.Although much has been learned on how low energy status and glucose starvation activate AMPK,how AMPK activity is properly controlled in vivo is still poorly understood.Here we report that UHRF1,an epigenetic regulator highly expressed in proliferating and cancer cells,interacts with AMPK and serves to suppress AMPK activity under both basal and stressed conditions.As a nuclear protein,UHRF1 promotes AMPK nuclear retention and strongly suppresses nuclear AMPK activity toward substrates H2B and EZH2.Importantly,we demonstrate that UHRF1 also robustly inhibits AMPK activity in the cytoplasm compartment,most likely as a consequence of AMPK nucleocytoplasmic shuttling.Mechanistically,we found that UHRF1 has no obvious effect on AMPK activation by upstream kinases LKB1 and CAMKK2 but inhibits AMPK activity by acting as a bridging factor targeting phosphatase PP2A to dephosphorylate AMPK.Hepatic overexpression of UHRF1 showed profound effects on glucose and lipid metabolism in wild-type mice but not in those with the liver-specific knockout of AMPKα1/α2,whereas knockdown of UHRF1 in adipose tissue led to AMPK activation and reduced sizes of adipocytes and lipogenic activity,highlighting the physiological significance of this regulation in glucose and lipid metabolism.Thus,our study identifies UHRF1 as a novel AMPK gate-keeper with critical roles in cellular metabolism. | Xiang Xu Guangjin Ding Caizhi Liu Yuhan Ding Xiaoxin Chen Xiaoli Huang Chen-Song Zhang Shanxin Lu Yunpeng Zhang Yuanyong Huang Zhaosu Chen Wei Wei Lujian Liao Shu-Hai Lin Jingya Li Wei Liu Jiwen Li Sheng-Cai Lin Xinran Ma Jiemin Wong | 2022 | Cell Research2022，32，1： | 3 |
| 3 | Nickel and potassium co-modified β-Mo_2C catalyst for CO conversion显示文摘Nickel and potassium co-modified β-Mo2C catalysts were prepared and used for CO hydrogenation reaction. The major products over β-Mo2C were C1-C4 hydrocarbons, only few alcohols were obtained. Addition of potassium resulted in remarkable selectivity shift from hydrocarbons to alcohols at the expense of CO conversion over β-Mo2C. Moreover, it was found that potassium enhanced the ability of chain propagation with a higher C2+OH production. Modified by nickel, β-Mo2C showed a relatively high CO conversion, however, the products were similar to those of pure β-Mo2C. When co-modified by nickel and potassium, β-Mo2C exhibited high activity and selectivity towards mixed alcohols synthesis, and also the whole chain propagation to produce alcohols especially for the stage of C1OH to C2OH was remarkably enhanced. It was concluded that the Ni and K had, to some extent, synergistic effect on CO conversion. | Minglin Xiang Juan Zou Debao Li Wenhuai Li Yuhan Sun Xichun She | 2009 | Journal of Natural Gas Chemistry2009，18，2： | 2 |
| 4 | Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant. | Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu | 2023 | Science China(Life Sciences)2023，66，5： | 2 |
| 5 | Mirror-enhanced scanning light-field microscopy for long-term high-speed 3D imaging with isotropic resolution显示文摘Various biological behaviors can only be observed in 3D at high speed over the long term with low phototoxicity.Light-field microscopy(LFM)provides an elegant compact solution to record 3D information in a tomographic manner simultaneously,which can facilitate high photon efficiency.However,LFM still suffers from the missing-cone problem,leading to degraded axial resolution and ringing effects after deconvolution.Here,we propose a mirrorenhanced scanning LFM(MiSLFM)to achieve long-term high-speed 3D imaging at super-resolved axial resolution with a single objective,by fully exploiting the extended depth of field of LFM with a tilted mirror placed below samples.To establish the unique capabilities of MiSLFM,we performed extensive experiments,we observed various organelle interactions and intercellular interactions in different types of photosensitive cells under extremely low light conditions.Moreover,we demonstrated that superior axial resolution facilitates more robust blood cell tracking in zebrafish larvae at high speed. | Bo Xiong Tianyi Zhu Yuhan Xiang Xiaopeng Li Jinqiang Yu Zheng Jiang Yihan Niu Dong Jiang Xu Zhang Lu Fang Jiamin Wu Qionghai Dai | 2021 | Light(Science & Applications)2021，10，12： | 1 |
| 6 | Catalytic performance of Fe modified K/Mo_2C catalyst for CO hydrogenation显示文摘Fe modified and un-modified K/Mo2C were prepared and investigated as catalysts for CO hydrogenation reaction. Compared with K/Mo2C catalyst, the addition of Fe increased the production of alcohols, especially the C2+OH. Meanwhile, considerable amounts of C5+ hydrocar- bons and C2= -C4= were formed, whereas methane selectivity greatly decreased. Also, the activity and selectivity of the catalyst were readily affected by the reaction pressure and temperature employed. According to the XPS results, Mo4+ might be responsible for the production of alcohols, whereas the low valence state of Mo species such as Mo0 and/or Mo2+ might be account for the high activity and selectivity toward hydrocarbons. | Minglin Xiang Dudu Wu Juan Zou Debao Li Yuhan Sun Xichun She | 2011 | Journal of Natural Gas Chemistry2011，20，5： | 1 |
| 7 | A short review of heterogeneous catalytic process for mixed alcohols synthesis via syngas显示文摘 | Fang Kegong Li Debao Lin Minggui Xiang Minglin Wei Wei Sun Yuhan | 2009 | Catalysis Today2009，147，： | 1 |
| 8 | Analysis and Defense of Network Attacking Based on the Linux Server显示文摘The kernel of the Linux server is analyzed to find out the main cause of the server’s denial of service when it is attacked. In the kernel, when the connection request information memory is full, the new connection request is discarded. Therefore, the printk function was used to alert the kernel output log when the memory was full, the processing of discarding the connection request in the kernel was changed, and the function tcp_syn_flood_action was applied to full memory processing. In the function tcp_syn_flood_action, the free function was used to release the memory according to the condition, so that the new connection request has a storage space, thereby offering the server’s normal service. Finally, the proposed defense technology is verified to be effective. | Dapeng Lang Wei Ding Yuhan Xiang Xiangyu Liu | 2019 | 国际计算机前沿大会会议论文集2019，，1： | 0 |
| 9 | Petrochemical eigenvalues and diagrams for the identification of metamorphic rocks'protolith,taking the host rocks of Dashuigou tellurium deposit in China as an example显示文摘The Dashuigou tellurium deposit is the world’s only known independent tellurium deposit.By restoring metamorphic rocks’protolith,we seek to understand not only the development and evolution trajectory of the region but also the origin of the relevant deposits.While there are many ways to restore metamorphic rocks’protolith,we take the host metamorphic rocks of Dashuigou tellurium deposit and leverage various petrochemical eigenvalues and related diagrams previously proposed to reveal the deposit’s host metamorphic rocks’protolith.The petrochemical eigenvalues include molecular number,Niggli’s value,REE parity ratio,CaO/Al_(2)O_(3)ratio,Fe^(3+) /(Fe^(3+) -+Fe^(2+) )ratio,chondrite-normalized REE value,logarithmic REE value,various REE eigenvalues including scandium,Eu/Sm ratio,total REE amount,light and heavy REEs,δEu,Eu anomaly,Sm/Nd ratio,and silicon isotope δ^(30) SiNBS-29‰,etc.The petrochemical plots include ACMs,100 mg-c-(al+alk),SiO_(2)-(Na_(2)O+K_(2)O),(al+fm)-(c+alk)versus Si,FeO+Fe_(2)O^(3+) TiO)-Al_(2)O_(3)-MgO,c-mg,Al_(2)O_(3)-(Na_(2)O+K_(2)O),chondrite-normalized REE model,La/Yb-REE,and Sm/Nd ratio,etc.On the basis of these comprehensive analyses,the following conclusions are drawn,starting from the many mantle-derived types of basalt developed in the study area of different geological ages,combined with the previously published research results on the deposit s fluid inclusions and sulfur and lead isotopes.The deposit is formed by mantle degassing in the form of a mantle plume in the late Yanshanian orogeny.The degassed fluids are rich in nano-sc ale substances including Fe,Te,S,As,Bi,Au,Se,H_(2),CO_(2),N_(2),H_(2)O,and CH_(4),which are enriched by nano-effect,and then rise to a certain part of the crust in the form of mantle plume along the lithospheric fault to form the deposit.The ultimate power for tellurium mineralization was from H_(2)flow with high energy,which was produced through radiation from the melted iron of the Earth’s outer core.The H,flow results in the Earth’s degassing,as well as the mantle and crust’s uplift. | Jianzhao Yin Shoupu Xiang Yuhong Chao Yuhan Yin Hongyun Shi | 2023 | Acta Geochimica2023，42，1： | 0 |
| 10 | Autonomous vehicles for micro-mobility显示文摘Autonomous vehicles have been envisioned for more than 100 years.One of the first suggestions was a front cover of Scientific America back in 1916.Today,it is possible to get cars that drive autonomously for extended distances.We are also starting to see micro-mobility solutions,such as the Nuro vehicles for pizza delivery.Building autonomous cars that can operate in urban environments with a diverse set of road-users is far from trivial.Early 2018 the Contextual Robotics Institute at UC San Diego launched an effort to build a full stack autonomous vehicle for micro-mobility.The motivations were diverse:i)development of a system for operation in an environment with many pedestrians,ii)design of a system that does not rely on dense maps(or HD-maps as they are sometimes named),iii)design strategies to build truly robust systems,and iv)a framework to educate next-generation engineers.In this paper,we present the research effort of design,prototyping,and evaluation of such a vehicle.From the evaluation,several research directions are explored to account for shortcomings.Lessons and issues for future work are additionally drawn from this work. | Henrik Christensen David Paz Hengyuan Zhang Dominique Meyer Hao Xiang Yunhai Han Yuhan Liu Andrew Liang Zheng Zhong Shiqi Tang | 2021 | Autonomous Intelligent Systems2021，1，1： | 0 |
| 11 | Single-step thermal carburization synthesis of supported molybdenum carbides from molybdenum-containing methyl-silica显示文摘A novel synthesis route to obtain highly dispersed molybdenum carbides in porous silica is described. The synthesis was carried out by a single-step heat treatment of molybdenum-containing and methyl-modified silica (Mo-M-SiO2) in argon atmosphere at 973 K. Mo-M-SiO2 precursor was facilely obtained via a one-pot synthesis route, using (NH4)6Mo7O24 4H2O (AHM) as molybdenum sources and polymethylhydrosiloxane (PMHS) as silica sources at the initial synthetic step. The optimal C/Mo molar ratio in reaction system for complete carburization of molybdenum species was 7. The carburization process of molybdenum species followed a nontopotactic route involving a MoO2 intermediate phase, which was evidenced by XRD, N2 adsorption-desorption and in situ XPS. Formation mechanism of Mo-M-SiO2 precursor was also proposed by observation of the reaction between AHM and PMHS with TEM. Furthermore, by adding TEOS into silica sources and adjusting TEOS/PMHS mass ratio, crystal phase of molybdenum carbides transferred from β-Mo2C to α-MoC1-x, and SiO2 structure changed from microporous to micro/mesoporous. Catalytic performances of samples were tested using CO hydrogenation as a probe reaction. The supported molybdenum carbides exhibited high selectivity for higher alcohol synthesis compared with bulk β-Mo2C and α-MoC1-x. | Juan Zou Minglin Xiang Bo How Dong Wu Yuhan Sun | 2011 | Journal of Natural Gas Chemistry2011，20，3： | 0 |
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