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| 1 | Pancreatic stents for the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis should be inserted up to the pancreatic body or tail显示文摘AIM To investigate the location to which a pancreatic stent should be inserted to prevent post-endoscopic retrograde cholangiopancreatography(ERCP) pancreatitis(PEP).METHODS Over a ten-year period at our hospital, 296 patients underwent their first ERCP procedure and had a pancreatic stent inserted; this study included 147 patients who had ERCP performed primarily for biliary investigation and had a pancreatic stent inserted to prevent PEP. We dividedthese patients into two groups: 131 patients with a stent inserted into the pancreatic head(head group) and 16 patients with a stent inserted up to the pancreatic body or tail(body/tail group). Patient characteristics and ERCP factors were compared between the groups.RESULTS Pancreatic amylase isoenzyme(p-AMY) levels in the head group were significantly higher than those in the body/tail group [138.5(7.0-2086) vs 78.5(5.0-1266.5), P = 0.03] [median(range)]. No cases of PEP were detected in the body/tail group [head group, 12(9.2%)]. Of the risk factors for post-ERCP hyperamylasemia(≥ p-AMY median, 131 IU/L), procedure time ≥ 60 min [odds ratio(OR) 2.65, 95%CI: 1.17-6.02, P = 0.02) and stent insertion into the pancreatic head(OR 3.80, 95%CI: 1.12-12.9, P = 0.03) were identified as independent risk factors by multivariate analysis.CONCLUSION Stent insertion up to the pancreatic body or tail reduces the risk of post-ERCP hyperamylasemia and may reduce the risk of PEP. | Mitsuru Sugimoto Tadayuki Takagi Rei Suzuki Naoki Konno Hiroyuki Asama Yuki Sato Hiroki Irie Ko Watanabe Jun Nakamura Hitomi Kikuchi Yuichi Waragai Mika Takasumi Takuto Hikichi Hiromasa Ohira | 2018 | World Journal of Gastroenterology2018，24，22： | 13 |
| 2 | Comparison of decompression tubes with metallic stents for the management of right-sided malignant colonic obstruction显示文摘BACKGROUND Emergency surgical resection is a standard treatment for right-sided malignant colonic obstruction; however, the procedure is associated with high rates of mortality and morbidity. Although a bridge to surgery can be created to obviate the need for emergency surgery, its effects on long-term outcomes and the most practical management strategies for right-sided malignant colonic obstruction remain unclear.AIM To determine the appropriate management approach for right-sided malignant colonic obstruction.METHODS Forty patients with right-sided malignant colonic obstruction who underwent curative resection from January 2007 to April 2017 were included in the study.We compared the perioperative and long-term outcomes of patients who received bridges to surgery established using decompression tubes and those created using self-expandable metallic stents(SEMS). The primary outcome was the overall survival duration(OS) and the secondary endpoints were the diseasefree survival(DFS) duration and the preoperative and postoperative morbidity rates. Analysis was performed on an intention-to-treat basis.RESULTS There were 21 patients in the decompression tube group and 19 in the SEMS group. There were no significant differences in the perioperative morbidity rates of the two groups. The OS rate was significantly higher in the decompression tube group than in the SEMS group(5-year OS rate; decompression tube 79.5%,SEMS 32%, P = 0.043). Multivariate analysis revealed that the bridge to surgery using a decompression tube was significantly associated with the OS(hazard ratio, 17.41; P = 0.004). The 3-year DFS rate was significantly higher in thedecompression tube group than in the SEMS group(68.9% vs 45.9%; log-rank test,P = 0.032). A propensity score–adjusted analysis also demonstrated that the prognosis was significantly better in the decompression tube group than in the SEMS group.CONCLUSION The bridge to surgery using trans-nasal and trans-anal decompression tubes for right-sided malignant colonic obstruction is safe and may improve long-term outcomes. | Yoshiyuki Suzuki Konosuke Moritani Yuki Seo Takayuki Takahashi | 2019 | World Journal of Gastroenterology2019，25，16： | 5 |
| 3 | Carbon dioxide insufflation in esophageal endoscopic submucosal dissection reduces mediastinal emphysema: A randomized, double-blind, controlled trial显示文摘AIM To assess the efficacy of CO2 insufflation for reduction of mediastinal emphysema(ME) immediately after endoscopic submucosal dissection(ESD).METHODS A total of 46 patients who were to undergo esophageal ESD were randomly assigned to receive either CO2 insufflation(CO2 group, n = 24) or air insufflation(Air group, n = 22). Computed tomography(CT) was carried out immediately after ESD and the next morning. Pain and abdominal distention were chronologically recorded using a 100-mm visual analogue scale(VAS). The volume of residual gas in the digestive tract was measured using CT imaging. RESULTS The incidence of ME immediately after ESD in the CO2 group was significantly lower than that in the Air group(17% vs 55%, P = 0.012). The incidence of ME the next morning was 8.3% vs 32% respectively(P= 0.066). There were no differences in pain scores or distention scores at any post-procedure time points. The volume of residual gas in the digestive tract immediately after ESD was significantly smaller in the CO2 group than that in the Air group(808 m L vs 1173 m L, P = 0.013).CONCLUSION CO2 insufflation during esophageal ESD significantly reduced postprocedural ME. CO2 insufflation also reduced the volume of residual gas in the digestive tract immediately after ESD, but not the VAS scores of pain and distention. | Yuki Maeda Dai Hirasawa Naotaka Fujita Tetsuya Ohira Yoshihiro Harada Taku Yamagata Yoshiki Koike Kenjirou Suzuki | 2016 | World Journal of Gastroenterology2016，22，32： | 3 |
| 4 | Systemic hemodynamics in advanced cirrhosis: Concerns during perioperative period of liver transplantation显示文摘Advanced liver cirrhosis is usually accompanied by portal hypertension. Long-term portal hypertension results in various vascular alterations. The systemic hemodynamic state in patients with cirrhosis is termed a hyperdynamic state. This peculiar hemodynamic state is characterized by an expanded blood volume, high cardiac output, and low total peripheral resistance. Vascular alterations do not disappear even long after liver transplantation(LT), and recipients with cirrhosis exhibit a persistent systemic hyperdynamic state even after LT. Stability of optimal systemic hemodynamics is indispensable for adequate portal venous flow(PVF) and successful LT, and reliable parameters for optimal systemic hemodynamics and adequate PVF are required. Even a subtle disorder in systemic hemodynamics is precisely indicated by the balance between cardiac output and blood volume. The indocyanine green(ICG) kinetics reflect the patient's functional hepatocytes and effective PVF, and PVF is a major determinant of the ICG elimination constant(kICG) in the well-preserved allograft. The kICG value is useful to set the optimal PVF during living-donor LT and to evaluate adequate PVF after LT. Perioperative management has a large influence on the postoperative course and outcome; therefore, key points and unexpected pitfalls for intensive management are herein summarized. Transplant physicians should fully understand the peculiar systemic hemodynamic behavior in LT recipients with cirrhosis and recognize the critical importance of PVF after LT. | Tomohide Hori Yasuhiro Ogura Yasuharu Onishi Hideya Kamei Nobuhiko Kurata Motoshi Kainuma Hideo Takahashi Shogo Suzuki Takashi Ichikawa Shoko Mizuno Tadashi Aoyama Yuki Ishida Takahiro Hirai Tomoko Hayashi Kazuko Hasegawa Hiromu Takeichi Atsunobu Ota Yasuhiro Kodera Hiroyuki Sugimoto Taku Iida Shintaro Yagi Kentaro Taniguchi Shinji Uemoto | 2016 | World Journal of Hepatology2016，8，25： | 3 |
| 5 | Predictive factors for the failure of endoscopic stent-instent self-expandable metallic stent placement to treat malignant hilar biliary obstruction显示文摘AIM To investigate the factors predictive of failure when placing a second biliary self-expandable metallic stents(SEMSs). METHODS This study evaluated 65 patients with an unresectable malignant hilar biliary obstruction who were examined in our hospital. Sixty-two of these patients were recruited to the study and divided into two groups: the success group, which consisted of patients in whom a stent-in-stent SEMS had been placed successfully, and the failure group, which consisted of patients in whom the stent-in-stent SEMS had not been placed successfully. We compared the characteristics of the patients, the stricture state of their biliary ducts, and the implemented endoscopic retrograde cholangiopancreatography(ERCP) procedures between the two groups.RESULTS The angle between the target biliary duct stricture and the first implanted SEMS was significantly larger in the failure group than in the success group. There were significantly fewer wire or dilation devices(ERCP catheter, dilator, or balloon catheter) passing the first SEMS cell in the failure group than in the success group. The cut-off value of the angle predicting stent-in-stent SEMS placement failure was 49.7 degrees according to the ROC curve(sensitivity 91.7%, specificity 61.2%). Furthermore, the angle was significantly smaller in patients with wire or dilation devices passing the first SEMS cell than in patients without wire or dilation devices passing the first SEMS cell. CONCLUSION A large angle was identified as a predictive factor for failure of stent-in-stent SEMS placement. | Mitsuru Sugimoto Tadayuki Takagi Rei Suzuki Naoki Konno Hiroyuki Asama Ko Watanabe Jun Nakamura Hitomi Kikuchi Yuichi Waragai Mika Takasumi Yuki Sato Takuto Hikichi Hiromasa Ohira | 2017 | World Journal of Gastroenterology2017，23，34： | 3 |
| 6 | Integrated in-process chatter monitoring and automatic suppression with adaptive pitch control in parallel turning显示文摘 | Shuntaro Yamato Yuki Yamada Kenichi Nakanishi Norikazu Suzuki Hayato Yoshioka Yasuhiro Kakinuma | 2018 | Advances in Manufacturing2018，6，3： | 2 |
| 7 | Screening for hilar biliary invasion in ampullary cancer patients显示文摘BACKGROUND The treatment for ampullary cancer is pancreatoduodenectomy or local ampullectomy.However,effective methods for the preoperative investigation of hilar biliary invasion in ampullary cancer patients have not yet been identified.AIM To determine the necessity of and an appropriate method for investigating hilar biliary invasion of ampullary cancer.METHODS Among 43 ampullary cancer patients,34 underwent endoscopic treatment(n=9)or surgery(n=25).The use of imaging findings(thickening and enhancement of the bile duct wall on contrast-enhanced computed tomography,irregularity on endoscopic retrograde cholangiography,thickening of the entire bile duct wall on intraductal ultrasonography(IDUS),and partial thickening of the bile duct wall on IDUS)and biliary biopsy results for diagnosing hilar biliary invasion of ampullary cancer was compared.RESULTS Hilar invasion was not observed in every patient.Among the patients who did not undergo biliary stent insertion,the combination of partial thickening of the bile duct wall on IDUS and biliary biopsy results showed the highest accuracy(100%)for diagnosing hilar biliary invasion.However,each imaging method and biliary biopsy yielded some false-positive results.CONCLUSION Although some false-positive results were obtained with each method,the combination of partial thickening of the bile duct wall on IDUS and biliary biopsy results was useful for diagnosing hilar biliary invasion of ampullary cancer.However,hilar invasion of ampullary cancer is rare;therefore,the investigation of hilar biliary invasion of ampullary cancer might be unnecessary. | Tadayuki Takagi Mitsuru Sugimoto Rei Suzuki Naoki Konno Hiroyuki Asama Yuki Sato Hiroki Irie Jun Nakamura Mika Takasumi Minami Hashimoto Tsunetaka Kato Ryoichiro Kobashi Takumi Yanagita Yuko Hashimoto Shigeru Marubashi Takuto Hikichi Hiromasa Ohira | 2022 | World Journal of Gastrointestinal Endoscopy2022，14，9： | 2 |
| 8 | Lack of Cholecystokinin-A Receptor Enhanced Gallstone Formation: A Study in CCK-A Receptor Gene Knockout Mice显示文摘 | Norikazu Sato Kyoko Miyasaka Shinji Suzuki Setsuko Kanai Minoru Ohta Takako Kawanami Yuki Yoshida Soichi Takiguchi Tetsuo Noda Yutaka Takata Akihiro Funakoshi | 2003 | Digestive Diseases and Sciences2003，，10： | 2 |
| 9 | Rapid detection of gene mutations responsible for non-syndromic aortic aneurysm and dissection using two different methods: resequencing microarray technology and next-generation sequencing显示文摘 | Haruya Sakai Shinichi Suzuki Takeshi Mizuguchi Kiyotaka Imoto Yuki Yamashita Hiroshi Doi Masakazu Kikuchi Yoshinori Tsurusaki Hirotomo Saitsu Noriko Miyake Munetaka Masuda Naomichi Matsumoto | 2012 | Human Genetics2012，，4： | 1 |
| 10 | Boundary-representable partition of unity for image magnification显示文摘This paper proposes a simple yet efective algorithm to magnify 2D/3D images with preserving discontinuities of intensity.Our algorithm is based on the partition of unity(PU)approximation,which ofers many advantages such as smooth representation,noise-robustness,and precise representation.Unfortunately,PU encounters difculties when scaling images and maintaining boundaries within images owing to the nature of its approximation.To overcome this problem,we propose an approximation that preserves discontinuities.This is realized by dividing the local spherical support of PU into two parts along a locally detected discontinuity and by individually approximating intensities on each side of the discontinuity.This algorithm is suitable for magnifying a variety of images,including scanned documents,pictures,and CT-scanned images.To demonstrate the efectiveness of the proposed method,we show some experimental results for 2D/3D images. | NAGAI Yukie OHTAKE Yutaka YOKOTA Hideo SUZUKI Hiromasa | 2013 | Science China(Information Sciences)2013，56，11： | 1 |
| 11 | Aortic Arch Reconstruction by Transluminally Placed Endovascular Branched Stent Graft显示文摘 | Kanji Inoue Hiroaki Hosokawa Tomoyuki Iwase Mitsuru Sato Yuki Yoshida Katsuya Ueno Akiyoshi Tsubokawa Terumitsu Tanaka Shunichi Tamaki Takahiko Suzuki | 1999 | Circulation ( Suppl)1999，，19： | 1 |
| 12 | Intensive chemotherapy for elderly patients with acute myelogeneous leukemia: a propensity score analysis by the Japan Hematology and Oncology Clinical Study Group (J-HOCS)显示文摘 | Kumi Oshima Wataru Takahashi Yuki Asano-Mori Koji Izutsu Tsuyoshi Takahashi Yukihiro Arai Yasunori Nakagawa Kensuke Usuki Mineo Kurokawa Kenshi Suzuki Kinuko Mitani Yoshinobu Kanda | 2012 | Annals of Hematology2012，，10： | 1 |
| 13 | Availability and metabolism of ^77Se-methy lseleninic acid compared simultaneously with those of three related selenocompounds显示文摘 | SUZUKI K T YUKI O SUZUKI N | 2006 | Toxicology and Applied Pharmacology2006，217，1： | 1 |
| 14 | Prognostic Impact of Hypoxia-Inducible miRNA-210 in Patients with Lung Adenocarcinoma显示文摘 | Jun Osugi Yuka Kimura Yuki Owada Takuya Inoue Yuzuru Watanabe Takumi Yamaura Mitsuro Fukuhara Satoshi Muto Naoyuki Okabe Yuki Matsumura Takeo Hasegawa Athushi Yonechi Mika Hoshino Mitsunori Higuchi Yutaka Shio Hiroyuki Suzuki Mitsukazu Gotoh James L. Muls | 2015 | Journal of Oncology2015，，： | 1 |
| 15 | Surgical Results for Functional Univentricular Heart With Total Anomalous Pulmonary Venous Connection Over a 25-Year Experience显示文摘 | Yuki Nakayama Takeshi Hiramatsu Yusuke Iwata Toru Okamura Takeshi Konuma Goki Matsumura Kenji Suzuki Kyoko Hobo Toshio Nakanishi Hiromi Kurosawa Kenji Yamazaki | 2012 | The Annals of Thoracic Surgery2012，，2： | 1 |
| 16 | Usefulness of the thread‐traction method in esophageal endoscopic submucosal dissection: Randomized controlled trial显示文摘 | Yoshiki Koike Dai Hirasawa Naotaka Fujita Yuki Maeda Tetsuya Ohira Yoshihiro Harada Kenjiro Suzuki Taku Yamagata Megumi Tanaka | 2015 | Digestive Endoscopy2015，，3： | 1 |
| 17 | Suppression of T regs by anti‐glucocorticoid induced TNF receptor antibody enhances the antitumor immunity of interferon‐α gene therapy for pancreatic cancer显示文摘 | Kouichirou Aida Reina Miyakawa Koji Suzuki Kenta Narumi Takeshi Udagawa Yuki Yamamoto Tatsuya Chikaraishi Teruhiko Yoshida Kazunori Aoki | 2014 | Cancer Sci2014，，2： | 1 |
| 18 | Dose - Dependent hypocholes- terolemic actions of dietary apple polyphenol in rats fed cholesterol 显示文摘 | Kyoiehi Osada Takashi Suzuki Yuki Kawakami | 2006 | Lipids2006，41，2： | 1 |
| 19 | Optimal compressive force induces bone formation via increasing bone morphogenetic proteins production and decreasing their antagonists production by Saos-2 cells显示文摘 | Narihiro Mitsui Naoto Suzuki Masao Maeno Momoko Yanagisawa Yuki Koyama Kichibee Otsuka Noriyoshi Shimizu | 2005 | Life Sciences2005，，23： | 1 |
| 20 | Structural characteristics and optical properties of a series of solvatochromic fluorescent dyes displaying long-wavelength emission显示文摘 | Yosuke Ando Yuya Homma Yuki Hiruta Daniel Citterio Koji Suzuki | 2009 | Dyes and Pigments2009，，2： | 1 |
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