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| 1 | Meta-analysis of cognitive function in Chinese first-episode schizophrenia: MATRICS Consensus Cognitive Battery (MCCB) profile of impairment显示文摘Background Compromised neurocognition is a core feature of schizophrenia. With increasing studies researching cognitive function of Chinese patients with first-episode schizophrenia (FES) using MATRICS Consensus Cognitive Battery (MCCB), it is not clear about the level and pattern of cognitive impairment among this population. Aim To provide a meta-analysis systematically analysing studies of neurocognitive function using MCCB in Chinese patients with FES. Methods An independent literature search of both Chinese and English databases up to 13 March 2019 was conducted by two reviewers. Standardised mean difference (SMD) was calculated using the random effects model to evaluate the effect size. Results 56 studies (FES=3167, healthy controls (HC)=3017) were included and analysed. No study was rated as 'high quality' according to Strengthening the Reporting of Observational Studies in Epidemiology. Compared with HCs, Chinese patients with FES showed impairment with large effect size in overall cognition (SMD=-1.60,95% Cl -1.82 to -1.38,厂=67%) and all seven cognitive domains, with the SMD ranging from -0.87 to -1.41. In nine MCCB subtests, patients with FES showed significant difference in Symbol Coding (SMD=-1.90), Trail Making Test (TMT)(SMD=-1.36), Continuous Performance Test-Identical Pairs (SMD=-1.33), Hopkins Verbal Learning Test (SMD=-1.24), Brief Visuospatial Memory Test (SMD=-1.18), Mazes (SMD=-1.16), Category Fluency (SMD=-1.01), Spatial Span (SMD=-0.69) and Mayer-Salovey-Caruso Emotional Intelligence Test (SMD=-0.38). Conclusions Our meta-analysis demonstrates that Chinese patients with FES show neurocognitive deficits across all seven MCCB cognitive domains and all nine subtests, particularly in two neurocognitive domains: speed of processing and attention/vigilance, with the least impairment shown in social cognition. Symbol Coding and TMT may be the most sensitive tests to detect cognitive deficit in Chinese patients with FES. | Huijuan Zhang Yao Wang Yuliang Hu Yikang Zhu Tian hong Zhang Jijun Wang Ke Ma Chuan Shi Xin Yu Chunbo Li | 2019 | General Psychiatry2019，32，3： | 13 |
| 2 | Genome-wide association study of vitamin E in sweet corn kernels显示文摘Vitamin E,consisting of tocopherols and tocotrienols,serves as a lipid-soluble antioxidant in sweet corn kernels,providing nutrients to both plants and humans.Though the key genes involved in the vitamin E biosynthesis pathway have been identified in plants,the genetic architecture of vitamin E content in sweet corn kernels remains largely unclear.In the present study,an association panel of 204 inbred lines of sweet corn was constructed.Seven compounds of vitamin E were quantified in sweet corn kernels at 28 days after pollination.A total of 119 loci for vitamin E were identified using a genome-wide association study based on genotyping by sequencing,and a genetic network of vitamin E was constructed.Candidate genes identified were involved mainly in RNA regulation and protein metabolism.The known gene ZmVTE4,encodingγ-tocopherol methyltransferase,was significantly associated with four traits(α-tocopherol,α-tocotrienol,theα/γ-tocopherol ratio,and theα/γ-tocotrienol ratio).The effects of two causative markers on ZmVTE4 were validated by haplotype analysis.Finally,two elite cultivars(Yuetian 9 and Yuetian 22)with a 4.5-fold increase in the sum ofα-andγ-tocopherols were developed by marker-assisted selection,demonstrating the successful biofortification of sweet corn.Three genes(DAHPS,ADT2,and cmu2)involved in chorismate and tyrosine synthesis were significantly associated with theα/γ-tocotrienol ratio.These results shed light on the genetic architecture of vitamin E and may accelerate the nutritional improvement of sweet corn. | Yingni Xiao Yongtao Yu Gaoke Li Lihua Xie Xinbo Guo Jiansheng Li Yuliang Li Jianguang Hu | 2020 | The Crop Journal2020，8，2： | 7 |
| 3 | Estimation of Potential Risk of Reservoir-Induced Earthquake for the Proposed Hydroelectric Project on the Yangtze Gorges显示文摘The proposed hydroelectric project on the Yangtze Gorges will be one of the largest power stations in the world.The problem of induced seismicity to the project has attracted much attention throughout China and the world.A research program has been carried out by the State Seismological Bureau of China.Based on the size of the reservoir and the lithology,geological structure,permeability,stress state,and previous seismicity in the region,the potential risk of reservoir-induced seismicity has been estimated.The results suggest that,after impoundment in the reservoir area,the possibility of induced seismicity cannot be completely ruled out.The areas with potential risk may be in some gorges composed of karstified carbonate and plutonic granite around the dam site.However,the magnitude is expected to be limited owing to the small dimension of the induced seismogenic faults. | Hu Yuliang,Zhao Meng,Hu Ping,Ma Wentao,Yang Qingyuan,and Chen Xiancheng Institute of Geology,State Seismological Bureau,Beijing 100029,China | 1995 | Earthquake Research in China1995，9，4： | 4 |
| 4 | Restless legs syndrome following the use of ziprasidone: a case report显示文摘Restless legs syndrome(RLS)is a common sleep-related movement disorder characterised by an uncomfortable urge to move the legs that occurs during periods of inactivity.Although there have been many case reports on antipsychotic-induced RLS,ziprasidone has never been reported as a cause of RLS.We present a case of a female patient with schizophrenia who presented with symptoms of RLS following the administration of high doses of ziprasidone added to quetiapine and valproate.The patient’s symptoms of RLS occurred following the administration and titration of ziprasidone to 160 mg,and were relieved upon reducing the dose to 120 mg/day.Other potential causative medications and differential diagnoses that could have caused similar symptoms were excluded.Clinicians should be aware of the potential for ziprasidone-induced RLS.Dopamine and serotonin interaction could be the mechanism underlying ziprasidone-induced RLS. | Cuizhen Zhu Ran Bi Yuliang Hu Hui Zhou Daomin Zhu Brian Isaacson Qingwei Li Yezhe Lin | 2020 | General Psychiatry2020，33，2： | 3 |
| 5 | Efficacy,safety and immunogenicity of hexavalent rotavirus vaccine in Chinese infants显示文摘A randomized,double-blind,placebo-controlled multicenter trial was conducted in healthy Chinese infants to assess the efficacy and safety of a hexavalent live human-bovine reassortant rotavirus vaccine(HRV)against rotavirus gastroenteritis(RVGE).A total of 6400 participants aged 6-12 weeks were enrolled and randomly assigned to either HRV(n?3200)or placebo(n?3200)group.All the subjects received three oral doses of vaccine four weeks apart.The vaccine efficacy(VE)against RVGE caused by rotavirus serotypes contained in HRV was evaluated from 14 days after three doses of administration up until the end of the second rotavirus season.VE against severe RVGE,VE against RVGE hospitalization caused by serotypes contained in HRV,and VE against RVGE,severe RVGE,and RVGE hospitalization caused by natural infection of any serotype of rotavirus were also investigated.All adverse events(AEs)were collected for 30 days after each dose.Serious AEs(SAEs)and intussusception cases were collected during the entire study.Our data showed that VE against RVGE caused by serotypes contained in HRV was 69.21%(95%CI:53.31-79.69).VE against severe RVGE and RVGE hospitalization caused by serotypes contained in HRV were 91.36%(95%CI:78.45-96.53)and 89.21%(95%CI:64.51-96.72)respectively.VE against RVGE,severe RVGE,and RVGE hospitalization caused by natural infection of any serotype of rotavirus were 62.88%(95%CI:49.11-72.92),85.51%(95%CI:72.74-92.30)and 83.68%(95%CI:61.34-93.11).Incidences of AEs from the first dose to one month post the third dose in HRV and placebo groups were comparable.There was no significant difference in incidences of SAEs in HRV and placebo groups.This study shows that this hexavalent reassortant rotavirus vaccine is an effective,well-tolerated,and safe vaccine for Chinese infants. | Zhiwei Wu Qingliang Li Yan Liu Huakun Lv Zhaojun Mo Fangjun Li Qingchuan Yu Fei Jin Wei Chen Yong Zhang Teng Huang Xiaosong Hu Wei Xia Jiamei Gao Haisong Zhou Xuan Bai Yueyue Liu Zhenzhen Liang Zhijun Jiang Yingping Chen Jiuwei Zhang Jialiang Du Biao Yang Bo Xing Yantao Xing Ben Dong Qinghai Yang Chen Shi Tingdong Yan Bo Ruan Haiyun Shi Xingliang Fan Dongyang Feng Weigang Lv Dong Zhang Xiangchu Kong Liuyifan Zhou Dinghong Que Hong Chen Zhongbing Chen Xiang Guo Weiwei Zhou Cong Wu Qingrong Zhou Yuqing Liu Jian Qiao Ying Wang Xinguo Li Kai Duan Yuliang Zhao Gelin Xu Xiaoming Yang | 2022 | Virologica Sinica2022，37，5： | 2 |
| 6 | Isomorphisms of fiber spaces over Teichmüller spaces显示文摘We will be mainly concerned with some important fiber spaces over Teichmüller spaces, including the Bers fiber space and Teichmüller curve, establishing an isomorphism theorem between 'punctured' Teichmüller curves and determining the biholomorphic isomorphisms of these fiber spaces. | HU Yun SHEN Yuliang | 2006 | Science China Mathematics2006，49，7： | 2 |
| 7 | P-Cadherin Promotes Liver Metastasis and Is Associated with Poor Prognosis in Colon Cancer显示文摘 | Lichao Sun Hai Hu Liang Peng Zhuan Zhou Xuan Zhao Jian Pan Lixin Sun Zhihua Yang Yuliang Ran | 2011 | The American Journal of Pathology2011，，： | 1 |
| 8 | Highly efficient green InP-based quantum dot light-emitting diodes regulated by inner alloyed shell component显示文摘InP-based quantum dot light-emitting diodes(QLEDs),as less toxic than Cd-free and Pb-free optoelectronic devices,have become the most promising benign alternatives for the next generation lighting and display.However,the development of green-emitting InP-based QLEDs still remains a great challenge to the environmental preparation of InP quantum dots(QDs)and superior device performance.Herein,we reported the highly efficient green-emitting InP-based QLEDs regulated by the inner alloyed shell components.Based on the environmental phosphorus tris(dimethylamino)phosphine((DMA)3P),we obtained highly efficient InP-based QDs with the narrowest full width at half maximum(~35 nm)and highest quantum yield(~97%)by inserting the gradient inner shell layer ZnSe_(x)S_(1-x)without further post-treatment.More importantly,we concretely discussed the effect and physical mechanism of ZnSe_(x)S_(1-x)layer on the performance of QDs and QLEDs through the characterization of structure,luminescence,femtosecond transient absorption,and ultraviolet photoelectron spectroscopy.We demonstrated that the insert inner alloyed shell ZnSe_(x)S_(1-x)provided bifunctionality,which diminished the interface defects upon balancing the lattice mismatch and tailored the energy levels of InP-based QDs which could promote the balanced carrier injection.The resulting QLEDs applying the InP/ZnSe_(0.7)S_(0.3)/ZnS QDs as an emitter layer exhibited a maximum external quantum efficiency of 15.2%with the electroluminescence peak of 532 nm,which was almost the highest record of InP-based pure green-emitting QLEDs.These results demonstrated the applicability and processability of inner shell component engineering in the preparation of high-quallity InP-based QLEDs. | Peng Yu Sheng Cao Yuliang Shan Yuhe Bi Yaqi Hu Ruosheng Zeng Bingsuo Zou Yunjun Wang Jialong Zhao | 2022 | Light(Science & Applications)2022，11，7： | 1 |
| 9 | Inhibition of Toosendanin on the delayed rectifier potassium current in neuroblastoma=glioma NG108-15 cells显示文摘 | QIAN HU FENSHENG HUANG YULIANG SHI | 1997 | Brain Research1997，1997，： | 1 |
| 10 | On Strebel points显示文摘Any Beltrami coefficient μ on a hyperbolic Riemann surface X of infinite type represents a point [μ]T in the Teichmüller space T (X) and a point [μ]B in the tangent space of T (X) at the base point as well. The paper deals with the problem of determining whether that [μ]T is a Strebel point is equivalent to that [μ]B is an infinitesimal Strebel point. | HU Yun SHEN YuLiang | 2009 | Science China Mathematics2009，52，9： | 1 |
| 11 | Tumor-suppressive mir-663 gene induces mitotic catastrophe growth arrestin human gastric cancer cells显示文摘 | Jian Pan Hai Hu Zhuan Zhou Lichao Sun Liang Peng Long Yu Lixin Sun Jun Liu Zhihua Yang Yuliang Ran | 2010 | Oncology Reports2010，，1： | 1 |
| 12 | Effect of sulfated astragalus polysaccharide on cellular infectivity of infectious bursal disease virus显示文摘 | Huang Xiaoyan Wang Deyun Hu Yuliang | 2008 | International Journal of Biological Macromolecules2008，3，： | 1 |
| 13 | Assessing the effectiveness and safety of fiposornal paclitaxel in combination with cisplatin as first- line chemotherapy for patients with advanced NSCLC with regional lymph-node metastasis: study protocol for a randomized controlled trial ( PLC-GC trial) 显示文摘 | Hu L Liang G Yuliang W | 2013 | Trials2013，14，： | 1 |
| 14 | Effect of surfactant on zeta potential and rheology behavior of methylene bis (thiocyanate) suspension concentrate显示文摘Methylene bis(thiocyanate)(MBT) is insoluble in water, so suspension concentrate(SC) of MBT is extremely relied on surfactants. In this paper, SC of MBT was prepared with wet-grinding technology, and the effect of surfactants,such as Morwet D425(D425) and Morwet EFW(EFW)(two kinds of dispersant), on the Zeta potential and rheology behavior of MBT SC were investigated. The results showed that the Zeta potential absolute value of MBT SC increased with the increasing content of D425, and it decreased with the increasing content of EFW at acidic solution(pH = 4.5). In the combination system of D425 and EFW, Zeta potential of MBT SC decreased first and then increased with the increasing content of EFW. The relationship between shear rate(γ) and viscosity(η) was studied according to Herschel–Bulkley model: η = η0+ k/γ, and the relationship between shear rate(γ) and shear force(τ) was investigated according to:τ = τ0+Kγ~n. It was revealed that the mixed fluid belonged to Yield Pseudoplastic Fluid. | Jianfeng Hu Yan Cai Shan Lu Jiezhen Xu Zhongrun Yun Jianheng Huang Yuliang Wen Jinqing Qu | 2017 | Chinese Journal of Chemical Engineering2017，25，5： | 1 |
| 15 | Assessing the effectiveness and safety of liposomal paclitaxel in combination with cisplatin as first-line chemotherapy for patients with advanced NSCLC with regional lymph-node metastasis:study protocol for a randomized controlled trial(PLC-GC trial)显示文摘 | HU L LIANG G YULIANG W | | 0，，： | 1 |
| 16 | Human esophageal cancer endothelial cells increase tumor growth by incorporating with mouse endothelium 显示文摘 | Hu Hai Zhang Yushan Ran Yuliang | 2007 | Cancer Lett2007，252，1： | 1 |
| 17 | Assessing the effectiveness and safety of liposomal paclitaxel in combination with cisplatin as first-line chemotherapy for patients with advanced NSCLC with regional lymph-node metastasis: study protocol for a randomized controlled trial ( PLC-GC trial) 显示文摘 | Hu L Liang G Yuliang W | 2013 | Trials2013，14，1： | 1 |
| 18 | Preparation of bioconjugates of CdTe nanocrystals for cancer marker detection显示文摘 | HU Fengqin RAN Yuliang ZHOU Zhuan | 2006 | Nanotechnol2006，17，： | 1 |
| 19 | Induced seismicity at wujiangdu reservoir, China: a case induced in the karst area显示文摘 | Hu Yuliang Liu Zuyuan Yang Oingyuan Chen Xiancheng Hu Ping Ma Wentao Lei Jun | 1996 | Pure and Applied Geophysics PAGEOPH1996，，2： | 1 |
| 20 | Assessing the effectiveness andsafety of liposomal paclitaxel in combination with cisplatin as first -line chemotherapy for patients with advanced NSCLC with regionallymph - node metastasis : study protocol for a randomized controlledtrial (PLC-GC trial) 显示文摘 | Hu L Liang G Yuliang W | 2013 | Trials2013，14，： | 1 |
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