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| 1 | The Spatial Distribution and Attribute Parameter Statistics of Landslides Triggered by the May 12th,2008,MW7.9 Wenchuan Earthquake显示文摘A complete landslide inventory and attribute database is the importantly fundamental for the study of the earthquake-induced landslide.Substantial landslides were triggered by the MW7.9 Wenchuan earthquake on May 12th,2008.Google Earth images of preand post-earthquakes show that 52194 co-seismic landslides were recognized and mapped,with a total landslides area of 1021 km2.Based on the statistics,we assigned all landslide parameters and established the co-seismic landslides database,which includes area,length,and width of landslides,elevation of the scarp top and foot edge,and the top and bottom elevations of each located slope.Finally,the spatial distribution and the above attribute parameters of landslides were analyzed.The results show that the spatial distribution of the co-seismic landslides is extremely uneven.The landslides that mainly occur in a rectangular area(a width of 30 km of the hanging wall of the Yingxiu-Beichuan fault and a length of 120 km between Yingxiu and Beichuan)are obviously controlled by surface rupture,terrain,and peak ground acceleration.Meanwhile,a large number of small landslides(individual landslide area less than 10000 m2)contribute less to the total landslides area.The number of landslides larger than 10000 m2 accounts for 38.7%of the total number of co-seismic landslides,while the area of those landslides account for 88%of the total landslides area.The 52194 co-seismic landslides are caused by bedrock collapse that usually consists of three parts:source area,transport area,and accumulation area.However,based on the area-volume power-law relationship,the resulting regional landslide volume may be much larger than the true landslide volume if the landslide volume is calculated using the influenced area from each landslide. | DU Peng XU Yueren TIAN Qinjian ZHANG Weiheng LIU Shuang | 2020 | Earthquake Research in China2020,34,1: | 3 |
| 2 | Effect of Ermiao Fang with Xixin(Herba Asari Mandshurici) on bone marrow stem cell directional homing to a focal zone in an osteoarthritis rat model显示文摘OBJECTIVE: To investigate the effects of Ermiao Fang(EM) with medical guide Xixin(Herba Asari Mandshurici)(HAM) on bone marrow stem cell migration to a focal zone in osteoarthritis(OA) rats.METHODS: OA rats were induced by arthrectomy and assigned to sham-operated, model, EM, or EM plus HAM groups.All rats were injected with recombinant human granulocyte colony-stimulating factor 30μg·kg-1·d-1for7 days and treated with EMor EM plus HAM at 1.6 or 1.9 g·kg-1·d-1 for 3 or 6 weeks, respectively. Chondrocyte apoptosis and cartilage matrix components were tested by transferase-mediated deoxyuridine triphosphate-biotin nick end labeling assay and special staining. Levels of interleukin-1 beta(IL-1β) tumor necrosis factor alpha(TNF-α) nitric oxide(NO), and inducible nitric oxide synthase(iNOS) in serum were detected by enzyme-linked immunosorbent assay or radioimmunoassay. Matrix metalloproteinases(MMPs)-13,tissue inhibitors of metalloproteinases(TIMPs)-1,Bromodeoxyuridine(BrdU), cluster of differentiation 34(CD34), and stromal cell-derived factor 1(SDF-1) were measured by immunohistochemical assay.RESULTS:The EM and EM plus HAM groups had significantly less cartilage damage and synovium inflammation the model group. Moreover, the EM and EM plus HAM groups had less chondrocyte apoptosis and more proteoglycan and collagen content than the model group.The EM and EMplus HAM groups had obviously higher MMPs-13 and TIMPs-1 expression in the cartilage than the model group. Moreover, the two formula groups had less release of IL-1β, TNF-α, NO, and iNOS than model group. Importantly, the expressions of BrdU, CD34,and SDF-1 in cartilage were significantly higher in the EM and EM plus HAM-Medtreated rats than model group. Notably, the EM plus HAM treatment seemed to have the greatest effects.CONCLUSION: HAM improves the therapeutic effects of EM on OA rats by enhancing BMSC directional homing to the focal zone. | Ying Xu Guojing Dai Qian Liu Hongwei Zhu Weiheng Chen Ping Zhang Tiejun Zhao Na Lin | 2014 | Journal of Traditional Chinese Medicine2014,34,4: | 3 |
| 3 | Deciphering the superior thermoelectric property of posttreatment-free PEDOT:PSS/IL hybrid by X-ray and neutron scattering characterization显示文摘In this work,a polymer and ionic liquid(IL)hybrid with superior thermoelectric performance is prepared via a system design of the chemical composition,molar ratio of the constituent molecules and manipulating the structure in solution and dried films.The solution-casted hybrid film,consisting of poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)(PEDOT:PSS)and 1-ethyl-3-methylimidazolium tricyanomethanide(EMIM:TCM),shows the highest power factor of 175μW m^(−1) K^(−2) in the polymer hybrid prepared by a post-treatment-free method.With a set of complementary structure characterization methods,it is found that EMIM:TCM can induce the structure reorganization of PEDOT:PSS in solution from a core-shell model to a rod-like model,during which PEDOT partially separates from PSS that eases the conductive network formation.In addition,the oxidation level of PEDOT:PSS is reduced by adding EMIM:TCM.Based on which,the PEDOT:PSS/IL hybrid shows the best performance in optimizing the conductivity(1163 S cm^(−1))and Seebeck coefficient(38.8μV K^(−1))simultaneously. | Xin Li Ruike Zou Zhen Liu Jitendra Mata Ben Storer Yu Chen Weiheng Qi Zekun Zhou Peng Zhang | 2022 | npj Flexible Electronics2022,6,1: | 2 |
| 4 | Molecular analysis of cell-free DNA identifies distinct molecular features in patients with chemosensitive and chemorefractory small cell lung cancer显示文摘Dear Editor,Lung cancer is the predominant cause of cancer-related death worldwide[1].Non-small cell lung cancer accounts for 80%-85%and small cell lung cancer(SCLC)accounts for 15%-20%of all lung cancer cases[2].Patients with SCLC,a highly aggressive and poorly differentiated malignancy,have an alarming average 5-year overall sur-vival rate of less than 10%[3].Most patients with SCLC already show clinically detectable metastases at diag-nosis and have extremely poor prognoses,even when treated with multimodality therapy[4].Before the addi-tion of atezolizumab to chemotherapy became the first-line treatment of extensive-stage SCLC,chemotherapy is the primary treatment of SCLC[5]. | Jie Zhang Chen Tian Fang Lv Jianfei Wang Wenbo Han Jun Nie Ling Dai Weiheng Hu Xiaoling Chen Xiangjuan Ma Guangming Tian Di Wu Sen Han Yang Wang Jieran Long Ziran Zhang Jian Fang Henghui Zhang | 2019 | Cancer Communications2019,39,1: | 2 |
| 5 | Identification of Cinobufagin and Resibufogenin as Inhibitors of Enterovirus 71 Infection显示文摘 | CHEN Jiawen XU Lin SUN Shiyang ZHANG Huafei MA Tonghui SU Weiheng JIANG Chunlai | 2014 | Chemical Research in Chinese Universities2014,30,6: | 1 |
| 6 | Interpretation of the Spatial Distribution Characteristics of the Co-seismic Landslides Induced by the 1920 Haiyuan M81/2 Earthquake Using Remote Sensing Images显示文摘Analyzing the spatial distribution characteristics of earthquake-induced secondary disasters based on advanced techniques is significantly important,especially in understanding the process of strong earthquakes in the Loess Pateau.Using ArcGIS,this study interprets multi-temporal high-resolution satellite images,field investigation data,and historical seismic records.Major conclusions are obtained as follows:①Landslides induced by the Haiyuan earthquake are mainly distributed in the intersection area of the end of the Haiyuan fault and Liupanshan fault,as indicated by multiple dense distribution centers;②The landslide distribution of the Haiyuan Earthquake is determined by the distance to the fault,topographic relief,slope,lithology,and other factors.In detail,the closer the distance to the fault,the greater the density of the landslide.The greater the slope and relief of the terrain,the greater the density and the smaller the average area of a landslide.Compared with tertiary strata,Quaternary strata has a larger average area,and the density of the landslides is smaller;③The density curve of the death toll in the Haiyuan earthquake can be used as a reference for the distribution of co-seismic landslides.Several Haiyuan co-seismic landslides are distributed in the Tongwei landslide area;however,the major landslides here are induced by the 1718 Tongwei earthquake rather than the 1920 Haiyuan earthquake;④The co-seismic landslides of the Haiyuan earthquake exhibits the“slope effect”in the south-west plate of Haiyuan fault,presenting the dominant sliding direction towards the fault and epicenter;however,the“slope effect”is not evident in the northeast plate of the fault. | ZHANG Weiheng XU Yueren DU Peng LI Wenqiao TIAN Qinjian CHEN Lize | 2020 | Earthquake Research in China2020,34,4: | 1 |
| 7 | Addition of aprepitant improves protection against cisplatin-induced emesis when a conventional anti-emetic regimen fails显示文摘 | Weiheng Hu Jian Fang Jun Nie Ling Dai Xiaoling Chen Jie Zhang Xiangjuan Ma Guangming Tian Jindi Han | 2014 | Cancer Chemotherapy and Pharmacology2014,,6: | 1 |
| 8 | The kinase p38αfunctions in dendritic cells to regulate Th2-cell differentiation and allergic inflammation显示文摘Dendritic cells(DCs)play a critical role in controlling T helper 2(Th2)cell-dependent diseases,but the signaling mechanism that triggers this function is not fully understood.We showed that p38αactivity in DCs was decreased upon HDM stimulation and dynamically regulated by both extrinsic signals and Th2-instructive cytokines.p38α-specific deletion in cDC1s but not in cDC2s or macrophages promoted Th2 responses under HDM stimulation.Further study showed that p38αin cDC1s regulated Th2-cell differentiation by modulating the MK2−c-FOS−IL-12 axis.Importantly,crosstalk between p38α-dependent DCs and Th2 cells occurred during the sensitization phase,not the effector phase,and was conserved between mice and humans.Our results identify p38αsignaling as a central pathway in DCs that integrates allergic and parasitic instructive signals with Th2-instructive cytokines from the microenvironment to regulate Th2-cell differentiation and function,and this finding may offer a novel strategy for the treatment of allergic diseases and parasitic infection. | Miaomiao Han Jingyu Ma Suidong Ouyang Yanyan Wang Tingting Zheng Peishan Lu Zihan Zheng Weiheng Zhao Hongjin Li Yun Wu Baohua Zhang Ran Hu Kinya Otsu Xinguang Liu Ying Wan Huabin Li Gonghua Huang | 2022 | Cellular & Molecular Immunology2022,19,7: | 1 |
| 9 | Melatonin mitigates cold-induced damage to pepper seedlings by promoting redox homeostasis and regulating antioxidant profiling显示文摘This study assessed the influence of exogenous ME in the mitigation of cold damage in pepper seedlings. Melatonin(ME) is a dynamic molecule that helps plants cope with stress in several ways. Cold stress(CS) is one of the most important environmental factors that restrict plant growth and yield. Pepper(Capsicum annuum L.) is a valuable commercial crop, highly sensitive to CS. Thus, identifying an efficient strategy to mitigate cold damage is critical for long-term pepper production. For this purpose, the roots of pepper seedlings were pretreated with ME(5 μmol · L^(-1)) and exposed to CS for 7 d. The results indicated that CS suppressed pepper growth, hampered photosynthetic capacity, and damaged root architecture in pepper plants. In contrast, the production of reactive oxygen species(ROS), malondialdehyde(MDA), electrolyte leakage(EL), proline, and soluble sugars were enhanced in plants under CS. ME(5 μmol · L^(-1)) pretreatment reduced the negative effects of CS by recovering plant growth, root traits, gas exchange elements, and pigment molecules compared to CS control treatment. Furthermore, ME application efficiently reduced oxidative stress markers [hydrogen peroxide(H_(2)O_(2)), superoxide ion(O_(2)^(·-)), EL, and MDA] while increasing proline and soluble sugar content in pepper leaves. ME application combined with CS further increased antioxidant enzymes and related gene expression. Collectively, our results confirmed the mitigating potential of ME supplementation for CS by maintaining pepper seedling growth,improving the photosynthesis apparatus, regulating pigments, and osmolyte content. | Muhammad Ahsan Altaf Yuanyuan Hao Huangying Shu Weiheng Jin Chuhao Chen Lin Li Yu Zhang Muhammad Ali Mumtaz Huizhen Fu Shanhan Cheng Guopeng Zhu Zhiwei Wang | 2024 | Horticultural Plant Journal2024,10,2: | 0 |
| 10 | Capacitive energy storage from single pore to porous electrode identified by frequency response analysis显示文摘Rate capability,peak power,and energy density are of vital importance for the capacitive energy storage(CES)of electrochemical energy devices.The frequency response analysis(FRA)is regarded as an efficient tool in studying the CES.In the present work,a bi-scale impedance transmission line model(TLM)is firstly developed for a single pore to a porous electrode.Not only the TLM of the single pore is reparameterized but also the particle packing compactness is defined in the bi-scale.Subsequently,the CES properties are identified by FRA,focused on rate capability vs.characteristic frequency,peak power vs.equivalent series resistance,and energy density vs.low frequency limiting capacitance for a single pore to a porous electrode.Based on these relationships,the CES properties are numerically simulated and theoretically predicted for a single pore to a porous electrode in terms of intra-particle pore length,intra-particle pore diameter,inter-particle pore diameter,electrolyte conductivity,interfacial capacitance&exponent factor,electrode thickness,electrode apparent surface area,and particle packing compactness.Finally,the experimental diagnosis of four supercapacitors(SCs)with different electrode thicknesses is conducted for validating the bi-scale TLM and gaining an insight into the CES properties for a porous electrode to a single pore.The calculating results suggest,to some extent,the inter-particle pore plays a more critical role than the intra-particle pore in the CES properties such as the rate capability and the peak power density for a single pore to a porous electrode.Hence,in order to design a better porous electrode,more attention should be given to the inter-particle pore. | Weiheng Li Qiu-An Huang Yu Li Yuxuan Bai Nan Wang Jia Wang Yongming Hu Yufeng Zhao Xifei Li Jiujun Zhang | 2023 | Journal of Energy Chemistry2023,,2: | 0 |
| 11 | Continuouss Three-Dimensional Printing of Architected Piezoelectric Sensors in Minutes显示文摘Additive manufacturing(AM),also known as three-dimensional(3D)printing,is thriving as an effective and robust method in fabricating architected piezoelectric structures,yet most of the commonly adopted printing techniques often face the inherent speed-accuracy trade-off,limiting their speed in manufacturing sophisticated parts containing micro-/nanoscale features.Herein,stabilized,photo-curable resins comprising chemically functionalized piezoelectric nanoparticles(PiezoNPs)were formulated,from which microscale architected 3D piezoelectric structures were printed continuously via micro continuous liquid interface production(μCLIP)at speeds of up to~60μm s^(-1),which are more than 10 times faster than the previously reported stereolithography-based works.The 3D-printed functionalized barium titanate(f-BTO)composites reveal a bulk piezoelectric charge constant d33 of 27.70 pC N^(-1) with the 30 wt%f-BTO.Moreover,rationally designed lattice structures that manifested enhanced,tailorable piezoelectric sensing performance as well as mechanical flexibility were tested and explored in diverse flexible and wearable self-powered sensing applications,e.g.,motion recognition and respiratory monitoring. | SiyingLiu Wenbo Wang Weiheng Xu Luyang Liu Wenlong Zhang Kenan Song Xiangfan Chen | 2022 | Research2022,,4: | 0 |
| 12 | Model reduction of fractional impedance spectra for time–frequency analysis of batteries, fuel cells, and supercapacitors显示文摘Joint time–frequency analysis is an emerging method for interpreting the underlying physics in fuel cells,batteries,and supercapacitors.To increase the reliability of time–frequency analysis,a theoretical correlation between frequency-domain stationary analysis and time-domain transient analysis is urgently required.The present work formularizes a thorough model reduction of fractional impedance spectra for electrochemical energy devices involving not only the model reduction from fractional-order models to integer-order models and from high-to low-order RC circuits but also insight into the evolution of the characteristic time constants during the whole reduction process.The following work has been carried out:(i)the model-reduction theory is addressed for typical Warburg elements and RC circuits based on the continued fraction expansion theory and the response error minimization technique,respectively;(ii)the order effect on the model reduction of typical Warburg elements is quantitatively evaluated by time–frequency analysis;(iii)the results of time–frequency analysis are confirmed to be useful to determine the reduction order in terms of the kinetic information needed to be captured;and(iv)the results of time–frequency analysis are validated for the model reduction of fractional impedance spectra for lithium-ion batteries,supercapacitors,and solid oxide fuel cells.In turn,the numerical validation has demonstrated the powerful function of the joint time–frequency analysis.The thorough model reduction of fractional impedance spectra addressed in the present work not only clarifies the relationship between time-domain transient analysis and frequency-domain stationary analysis but also enhances the reliability of the joint time–frequency analysis for electrochemical energy devices. | Weiheng Li Qiu-An Huang Yuxuan Bai Jia Wang Linlin Wang Yuyu Liu Yufeng Zhao Xifei Li Jiujun Zhang | 2024 | Carbon Energy2024,6,1: | 0 |