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| 1 | Terrestrial carbon sinks in China and around the world and their contribution to carbon neutrality显示文摘Enhancing the terrestrial ecosystem carbon sink(referred to as terrestrial C sink) is an important way to slow down the continuous increase in atmospheric carbon dioxide(CO_(2)) concentration and to achieve carbon neutrality target.To better understand the characteristics of terrestrial C sinks and their contribution to carbon neutrality,this review summarizes major progress in terrestrial C budget researches during the past decades,clarifies spatial patterns and drivers of terrestrial C sources and sinks in China and around the world,and examines the role of terrestrial C sinks in achieving carbon neutrality target.According to recent studies,the global terrestrial C sink has been increasing from a source of (-0.2±0.9) Pg C yr^(-1)(1 Pg=1015g)in the 1960s to a sink of (1.9±1.1) Pg C yr^(-1) in the 2010s.By synthesizing the published data,we estimate terrestrial C sink of 0.20–0.25 Pg C yr^(-1) in China during the past decades,and predict it to be 0.15–0.52 Pg C yr^(-1) by 2060.The terrestrial C sinks are mainly located in the mid-and high latitudes of the Northern Hemisphere,while tropical regions act as a weak C sink or source.The C balance differs much among ecosystem types:forest is the major C sink;shrubland,wetland and farmland soil act as C sinks;and whether the grassland functions as C sink or source remains unclear.Desert might be a C sink,but the magnitude and the associated mechanisms are still controversial.Elevated atmospheric CO_(2) concentration,nitrogen deposition,climate change,and land cover change are the main drivers of terrestrial C sinks,while other factors such as fires and aerosols would also affect ecosystem C balance.The driving factors of terrestrial C sink differ among regions.Elevated CO_(2) concentration and climate change are major drivers of the C sinks in North America and Europe,while afforestation and ecological restoration are additionally important forcing factors of terrestrial C sinks in China.For future studies,we recommend the necessity for intensive and long-term ecosystem C monitoring over broad geographic scale to improve terrestrial biosphere models for accurately evaluating terrestrial C budget and its dynamics under various climate change and policy scenarios. | Yuanhe Yang Yue Shi Wenjuan Sun Jinfeng Chang Jianxiao Zhu Leiyi Chen Xin Wang Yanpei Guo Hongtu Zhang Lingfei Yu Shuqing Zhao Kang Xu Jiangling Zhu Haihua Shen Yuanyuan Wang Yunfeng Peng Xia Zhao Xiangping Wang Huifeng Hu Shiping Chen Mei Huang Xuefa Wen Shaopeng Wang Biao Zhu Shuli Niu Zhiyao Tang Lingli Liu Jingyun Fang | 2022 | Science China(Life Sciences)2022，65，5： | 32 |
| 2 | CapOX as neoadjuvant chemotherapy for locally advanced operable colon cancer patients: a prospective single-arm phase Ⅱ trial显示文摘Objective: The aim of this prospective, single-arm phase II trial was to confirm the safety and efficacy of neoadjuvant chemotherapy(NAC) using oxaliplatin plus capecitabine(Cap OX) for patients with operable locally advanced colon cancer(CC).Methods: Patients with computed tomography-defined T4 or lymph node-positive CCs were enrolled. After radiological staging, patients were treated with at least 2 cycles of NAC consisting of 130 mg/m2 oxaliplatin on d 1,plus 1,000 mg/m2 capecitabine twice daily for 14 d every 3 weeks, followed by surgery, and then with the rest cycles of adjuvant chemotherapy. Radiological response was evaluated after 2 cycles of NAC. Tumor response, treatment toxicity, and surgical complications were recorded. The pathological response to therapy was evaluated according to the tumor regression grade(TRG) score. The primary endpoint was pathologic tumor response. This trial is registered in Clinical Trials.gov(No: NCT02415829).Results: Forty-seven patients were enrolled in the study. Forty-two patients completed the planned treatments.The total radiological response rate was 68%(32/47), including complete and partial response rates of 2%(1/47)and 66%(31/47), respectively. Stable disease was observed in 32%(15/47) and progressive disease was observed in none. Complete pathologic response, major regression, and at least moderate regression were achieved in 1(2%), 2(4%), and 29(62%) patients, respectively. Four patients developed grade 3 treatment toxicities. One patient with wound infection occurred after operation(1/47, 2%). There was no treatment-related death.Conclusions: Our results suggest that NAC with Cap OX is an effective and safe treatment option for patients with locally advanced CCs. | Fangqi Liu Li Yang Yuchen Wu Cong Li Jiang Zhao Adili Keranmu Hongtu Zheng Dan Huang Lei Wang Tong Tong Junyan Xu Ji Zhu Sanjun Cai Ye Xu | 2016 | Chinese Journal of Cancer Research2016，28，6： | 14 |
| 3 | Anti-fibrotic role and mechanism of Periplaneta americana extracts in CCl4-induced hepatic fibrosis in rats显示文摘 | Dingchun Li Wu Li Yihui Chen Lihui Liu Dehong Ma Hongtu Wang Lu Zhang Shenjun Zhao Qin Peng | 2018 | Acta Biochimica et Biophysica Sinica2018，50，5： | 14 |
| 4 | Study of GaAs optical fiber temperature sensor 显示文摘 | ZHAO Junliang GUAN Rongfeng ZHAO Hongtu | 2000 | Proceedings of SPIE(S0277-786X)2000，4223，： | 1 |
| 5 | Crystal structure of Cas1 in complex with branched DNA显示文摘Cas1 is a key component of the CRISPR adaptation complex,which captures and integrates foreign DNA into the CRISPR array,resulting in the generation of new spacers.We have determined crystal structures of Thermus thermophilus Cas1 involved in new spacer acquisition both in complex with branched DNA and in the free state.Cas1 forms an asymmetric dimer without DNA.Conversely,two asymmetrical dimers bound to two branched DNAs result in the formation of a DNA-mediated tetramer,dimer of structurally asymmetrical dimers,in which the two subunits markedly present different conformations.In the DNA binding complex,the N-terminal domain adopts different orientations with respect to the C-terminal domain in the two monomers that form the dimer.Substrate binding triggers a conformational change in the loop 164–177 segment.This loop is also involved in the 3′fork arm and 5′fork arm strand recognition in monomer A and B,respectively.This study provides important insights into the molecular mechanism of new spacer adaptation. | Jing Yang Jiazhi Li Jiuyu Wang Gang Sheng Min Wang Hongtu Zhao Yanhua Yang Yanli Wang | 2020 | Science China(Life Sciences)2020，63，4： | 1 |
| 6 | Interactive effects of elevated CO2 and nitrogen fertilization levels on photosynthesized carbon allocation in a temperate spring wheat and soil system显示文摘Increasing atmospheric CO2 concentration impacts the terrestrial carbon(C) cycle by affecting plant photosynthesis, the flow of photosynthetically fixed C belowground, and soil C pool turnover. For managed agroecosystems, how and to what extent the interactions between elevated CO2 and N fertilization levels influence the accumulation of photosynthesized C in crops and the incorporation of photosynthesized C into arable soil are in urgent need of exploration.We conducted an experiment simulating elevated CO2 with spring wheat(Triticum aestivum L.) planted in growth chambers.13C-enriched CO2 with an identical 13C abundance was continuously supplied at ambient and elevated CO2 concentrations(350 and 600 μmol mol-1, respectively) until wheat harvest.Three levels of N fertilizer application(equivalent to 80, 120, and 180 kg N ha-1 soil) were supplied for wheat growth at both CO2 concentrations. During the continuous 62-d 13CO2 labeling period, elevated CO2 and increased N fertilizer application increased photosynthesized C accumulation in wheat by 14%–24% and 11%–20%, respectively, as indicated by increased biomass production, whereas the C/N ratio in the roots increased under elevated CO2 but declined with increasing N fertilizer application levels. Wheat root deposition induced 1%–2.5% renewal of soil C after 62 d of 13CO2 labeling. Compared to ambient CO2, elevated CO2 increased the amount of photosynthesized C incorporated into soil by 20%–44%. However, higher application rates of N fertilizer reduced the net input of root-derived C in soil by approximately 8% under elevated CO2. For the wheat-soil system, elevated CO2 and increased N fertilizer application levels synergistically increased the amount of photosynthesized C. The pivotal role of plants in photosynthesized C accumulation under elevated CO2 was thereby enhanced in the short term by the increased N application. Therefore, robust N management could mediate C cycling and sequestration by influencing the interactions between plants and soil in agroecosystems under elevated CO2. | Yu ZHAO Chao LIANG Shuai SHAO Jie LI Hongtu XIE Wei ZHANG Fusheng CHEN Hongbo HEI Xudong ZHANG | 2021 | Pedosphere2021，31，1： | 1 |
| 7 | Dynamics of fertilizer-derived organic nitrogen fractions in an arable soil during a growing season显示文摘 | Huijie Lü Hongbo He Jinsong Zhao Wei Zhang Hongtu Xie Guoqing Hu Xiao Liu Yeye Wu Xudong Zhang | 2013 | 2013 (1-2)2013，，1： | 1 |
| 8 | Dynamics of fertilizer-derived organic nitrogen fractions in an arable soil during a growing season显示文摘 | Huijie Lü Hongbo He Jinsong Zhao Wei Zhang Hongtu Xie Guoqing Hu Xiao Liu Yeye Wu Xudong Zhang | 2013 | Plant and Soil (-)2013，，1： | 1 |
| 9 | Changing liver stiffness predict regression in advanced fibrosis patients with chronic hepatitis B,but not in moderate fibrosis patients显示文摘Background and objective:Liver stiffness measurement(LSM)may effectively correlate to the presence of liver fibrosis,but it is controversial to use for the prediction of clinical outcomes.Therefore,we aimed to evaluate the predictive value of liver stiffness for the regression of liver fibrosis.Methods:In this study,we collected data from a clinical cohort of patients who are received anti-virus therapies for 48 weeks.180 naive chronic hepatitis B(CHB)patients,who received paired LSM and liver biopsy with pre-and post-treatments were analyzed.Two methods(FibroScan and iLivTouch)test LSM.Result:The area under the receiver operating characteristics curve(AUROC)of changing LSM for fibrosis regression is higher in advanced fibrosis patients(F5/6)than in moderate fibrosis patients(F3/4)in both FibroScan(0.719,95%CI,0.590–0.848;P=0.003;vs 0.617,95%CI,0.379–0.856,P=0.282)and iLivTouch(0.707,95%CI,0.567–0.847;P=0.011;vs 0.583,95%CI,0.422–0.744;P=0.377).A higher kappa value was received in advanced stage than in moderate stage both in FibroScan(0.392,P=0.001 vs 0.265,P=0.053)and iLivTouch(0.326,P=0.019 vs 0.030,P=0.833).Cut-off set as 4.10 kPa(sen,69.4%;spe,73.9%)in FibroScan,as 4.25 kPa(sen,56.8%;spe,72.2%)in iLivTouch.Conclusion:The changing LSM can be used for predicting the liver fibrosis regression in advanced stage of CHB patients. | Zhengxin Li Tingting Zhu Zhimin Zhao Li Shen Gaofeng Chen Hongtu Gu Chenghai Liu | 2023 | Gastroenterology & Hepatology Research2023，5，1： | 0 |
| 10 | The Next Energy Revolution显示文摘In spite of the impact brought on by the global financial crisis of 2008,the clean energy industry has kept a fast pace of development,as international investment in clean energy shows rapid growth.In 2010, global financing and investment related to the clean energy industry was $243 billion, increasing 30 percent over 2009.In 2011。 | Zhao Hongtu | 2012 | Beijing Review2012，55，34： | 0 |
| 11 | The Belt and Road Initiative and International Industrial Transfer: Economic and International Implications显示文摘Theorists have discussed the Belt and Road Initiative relative to its political or policy implications, and world response to it has focused on analysis and commentary that assesses it geopolitically, with some even calling it a power play by China. Although the Belt and Road Initiative was proposed and has been promoted by China, it fundamentally is being developed within and adapted to laws of international industrial transfer and worldwide economic development trends, founding the initiative on universality and objectivity. The Belt and Road Initiative is an upgraded version or a new phase of the Go Out strategy adopted by the Chinese government to encourage Chinese enterprises to look abroad, which has been an important part of international industrial transfer. China is becoming a major output source in this new round of international industrial transfer, and the countries along the Belt and Road have become the major recipients. The new growth center of the global economy is likely to emerge along the Belt and Road, but the question of which countries in particular will take the lead in industrializing and accelerating economic growth through this industrial transfer will be decided in part through conditions such as development stage, technical maturity, cost level, and geographical location and in part through internal and external policy adjustment and choices made by the participating countries. | Zhao Hongtu | 2019 | Contemporary International Relations2019，29，4： | 0 |
| 12 | Some Thoughts on Sino-U.S. Energy Cooperation显示文摘China and the United States have constantly become interdependent in economic field, and both of them are facing increasingly severe challenges in energy security and price risks, thus cooperation between the two countries become more urgent and promises bright prospects. The two nations should further strengthen their strategic dialogues and exchanges, and try every means to promote substantial cooperation in energy field. | Zhao Hongtu | 2006 | Contemporary International Relations2006，16，1： | 0 |
| 13 | An Analysis of U.S.'Energy Independence'显示文摘'Energy independence' has been an age-old dream of the U.S.administration,and recently reemerged as a hot topic in the United States.The current decline of U.S. dependence on foreign energy is mainly caused by its economic downturn rather than genuine energy independence.Actually the U.S.still needs to import large quantities of crude oil in a rather long time. | Zhao Hongtu Hong Jianjun | 2012 | Contemporary International Relations2012，22，4： | 0 |
| 14 | International Energy Situation显示文摘The international energy situation has entered a new phase of change and readjustment. On the one hand, while imbalances in petroleum market supply-demand have been alleviated, the consuming states are now focusing on demand side management and development of new and renewable energy. There has been great progress in international energy security dialogue and cooperation. On the other hand, supply-demand market balance remains fragile , and restrictions due to insufficient energy investment are more evident. The concerned states have taken a stronger grip over their own resources. Implementation of energy diplomacy has also further complicated the relationship between energy and geo-politics, causing an upsurge of competition. | Zhao Hongtu Hong Jianjun(翻译) | 2007 | Contemporary International Relations2007，17，2： | 0 |
| 15 | How Changes to the International Energy Order Are Impacting Climate Negotiations显示文摘The rise in global energy consumption has made it more difficult to control global temperature rises.The world is now focused on the new big energy consumers,including China and India.The development of shale gas and other unconventional sources of oil and gas have had a mixed impact and the development of clean energy in the long term will help climate negotiations. | Zhao Hongtu Hong Jianjun | 2013 | Contemporary International Relations2013，23，6： | 0 |
| 16 | New Landscape of Energy Politics and Global Energy Governance显示文摘Since the 1990s,intern ational energy cooperation has advanced on all fronts,and energy governance has become a focal point of global governance.However,with the emerging anti-globalization tide and intensified competition among major countries in recent years,the trend of“politicizing”energy cooperation has been stronger. | Zhao Hongtu | 2023 | Contemporary World2023，，3： | 0 |
| 17 | China's Overseas Energy Investment:Myth and Reality显示文摘China's rapidly increasing demands for energy has been a subject for debate for years.To Chinese observers,the most important issue is how to safeguard energy supply and maintain economic growth.To most Western analysts,however,the more crucial issue is how Chinese energy policies and activities will affect world energy markets and world politics. | Zhao Hongtu | 2009 | Contemporary International Relations2009，19，2： | 0 |
| 18 | New Features of Int'l Energy Security Situation显示文摘In recent years, energy security has shown some new features. He-nce all countries of the world must adjust their strategy tosafeguard their energy security. | Dr. Zhao Hongtu is Associate Research Professor and Deputy Director of the Institute for World Economic Studies, CICIR. His major fields are energy security and international energy strategy. He has published many papers and books, and he is the co-editor and co-author of books of Chessboard of Global Energy and A Survey of International Strategic Resources. | 2005 | Contemporary International Relations2005，15，7： | 0 |
| 19 | Perspective of World Economy and China's External Economic Environment显示文摘Owing to a series of impacts of the '9·11 terrorist attack,' the accounting scandals of big companies, Iraq War and the SARS crisis in the past two years, the world economy that might have rebounded forcefully has been on a wavering process of slow recovery. | Tao Jian Chen Fengying Zhao Hongtu Zhang Yuncheng Jiang Yong Liang Jianwu Ni Jianjun Li Hongyan | 2003 | Contemporary International Relations2003，13，12： | 0 |
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