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| 1 | Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients显示文摘Pathogenic human coronavirus infections,such as severe acute respiratory syndrome CoV(SARS-CoV)and Middle East respiratory syndrome CoV(MERS-CoV),cause high morbidity and mortality[1,2].Recently,a severe pneumonia-associated respiratory syndrome caused by a new coronavirus(SARS-CoV-2)was reported in December 2019 in the city of Wuhan,Hubei province,China[3-5],which was also named as pneumonia-associated respiratory syndrome(PARS)[6]and can cause coronavirus disease 2019(COVID-19)to seriously endanger human health. | Yonggang Zhou Binqing Fu Xiaohu Zheng Dongsheng Wang Changcheng Zhao Yingjie Qi Rui Sun Zhigang Tian Xiaoling Xu Haiming Wei | 2020 | National Science Review2020，7，6： | 54 |
| 2 | Primary dolostone formation related to mantle-originated exhalative hydrothermal activities,Permian Yuejingou section,Santanghu area, Xinjiang,NW China显示文摘The Permian Lucaogou Formation is an important hydrocarbon source rock in the Junggar, Turpan, and Santanghu basins in Xinjiang, NW China. For the first time, dolostones associated with mantle-originated exhalative hydrothermal fluid flows are discovered in Yuejingou section in the Santanghu Basin area. They include dolomicrite, doloarenite, and a small amount of dolorudite, and are finely (0.05-0.15 cm thick) interlaminated with lime micrite and dolomicritic analcime laminites. Alkali feldspar and analcime grains are common in doloarenite and are interpreted as having been derived from analcime phonolites and peralkaline magmatic rocks. These magmatic fragments were brought up from subsurface by hydrothermal fluid flow and had experienced exhalative brecciation, transport, and deposition on the lake floor. The matrix consists dominantly of dolomite and ankerite smaller than 0.01 mm. The dolostones can be subdivided into four types on the basis of mineral composition and content. The detrital analcime and alkaline feldspar grains and tuff lithics are interpreted as intraclasts, which were deposited in an under-filled starved lake basin. The δ18OPDB values of dolostones are -5‰ to -21.1‰, and -11.9‰ on average; the 87Sr/86Sr ratios of dolostones are 0.70457 to 0.706194, and 0.705005 on average. These values, in combination with evidence of multi-episodes of peralkaline extrusion, suggest a mantle origin of the hydrothermal fluids, which may have promoted primary dolomite formation. The fluid from the upper mantle caused serpentinization of ultramafic rocks that intruded into the lower crust to obtain Mg2+ and Fe2+, and injected the ions into the lake water as the Mg and Fe sources for dolomite and ankerite. Hydro- thermal fluids associated with peralkaline magmatic rocks also provided Ca2+, Mg2+, Fe2+, and CO32-. Explosive breccias formed and dolostones were convoluted near the vent of hydrothermal fluid exhalation, whereas laminated dolostones formed farther away from the vent. The dolostones are primary dolomite deposition in an intracontinental rift basin and associated with mantle-originated hydrothermal fluids. They provide an insight into the origin of dolomite formation in the geologic history and clues to understand the sedimentary environments and tectonic conditions in northern Xinjiang during the late Paleozoic. | LIU YiQun JIAO Xin LI Hong YUAN MingSheng YANG Wan ZHOU XiaoHu LIANG Hao ZHOU DingWu ZHENG ChaoYang SUN Qin WANG ShuangShuang | 2012 | Science China Earth Sciences2012，55，2： | 17 |
| 3 | Monocular trajectory intersection method for 3D motion measurement of a point target显示文摘This article proposes a monocular trajectory intersection method,a videometrics measurement with a mature theoretical system to solve the 3D motion parameters of a point target.It determines the target’s motion parameters including its 3D trajectory and velocity by intersecting the parametric trajectory of a motion target and series of sight-rays by which a motion camera observes the target,in contrast with the regular intersection method for 3D measurement by which the sight-rays intersect at one point.The method offers an approach to overcome the technical failure of traditional monocular measurements for the 3D motion of a point target and thus extends the application fields of photogrammetry and computer vision.Wide application is expected in passive observations of motion targets on various mobile beds. | YU QiFeng SHANG Yang ZHOU Jian ZHANG XiaoHu LI LiChun | 2009 | Science China(Technological Sciences)2009，52，12： | 10 |
| 4 | The geochemical characteristics,geochronology and tectonic significance of the Carboniferous volcanic rocks of the Santanghu area in northeastern Xinjiang,China显示文摘The Santanghu area is located on the northeastern margin of the Junggar Basin,northern Xinjiang,Northwest China.The Carboniferous volcanic rocks in this area are widely distributed in Kaokesaiergaishan,Santanghu,Daheishan and Naomaohu districts,which are located to the north of the Kalameili Fault.These rocks,sourced from a cognate magma,consist of basic,intermediate,and acidic lavas,and pyroclastic rock.The basic volcanic rocks are enriched with large-ion lithophile elements(LILE),but are relatively depleted in high field strength elements(HFSE),and have an obvious negative Nb-Ta-Ti anomaly.They were most probably derived from a depleted mantle source,and during their ascent,these magmas were not contaminated by the crustal material as they underwent magma crystallization differentiation.Based on the Carboniferous volcanic assemblage and geochemical data,it is apparent that the early Carboniferous volcanism occurred in a subduction-related tectonic setting.New LA-ICP-MS zircon U-Pb analyses constrain the age of the andesite within the volcanic rocks as the early Carboniferous(328.9-331.3 Ma).Combined with the regional geological record,comprehensive analysis of the isotope geochronological data indicates that the subduction of the Junggar Ocean predates the early Carboniferous,and that the Santanghu island arc magmatism was induced by the subduction of the Junggar Ocean in the Carboniferous. | LI Wei LIU YiQun DONG YunPeng ZHOU XiaoHu LIU XiaoMing LI Hong FAN TingTing ZHOU DingWu XU XueYi CHEN JunLu | 2013 | Science China Earth Sciences2013，56，8： | 8 |
| 5 | Analysis of reconstructed annual precipitation from tree-rings for the past 500 years in the middle Qilian Mountain显示文摘The ring-width chronology of a Juniperus przewalskii tree from the middle of the Qilian Mountain was constructed to estimate the annual precipitation (from previous August to current July) since AD 1480.The reconstruction showed four major alternations of drying and wetting over the past 521 years.The rainy 16th century was followed by persistent drought in the 17th century.Moreover,relatively wet conditions persisted from the 18th to the beginning of 20th century until the recurrence of a drought during the 1920s and 1930s.Based on the Empirical Mode Decomposition method,eight Intrinsic Mode Functions (IMFs) were extracted,each representing unique fluctuations of the reconstructed precipitation in the time-frequency domain.The high amplitudes of IMFs on different timescales were often consistent with the high amount of precipitation,and vice versa.The IMF of the lowest frequency indicated that the precipitation has undergone a slow increasing trend over the past 521 years.The 2-3 year and 5-8 year time-scales reflected the characteristics of inter-annual variability in precipitation relevant to regional atmospheric circulation and the El Ni?o-Southern Oscillation (ENSO),respectively.The 10-13 year scale of IMF may be associated with changing solar activity.Specifically,an amalgamation of previous and present data showed that droughts were likely to be a historically persistent feature of the Earth's climate,whereas the probability of intensified rainfall events seemed to increase during the course of the 19th and 20th centuries.These changing characteristics in precipitation indicate an unprecedented alteration of the hydrological cycle,with unknown future amplitude.Our reconstruction complements existing information on past precipitation changes in the Qilian Mountain,and provides additional low-frequency information not previously available. | TIAN QinHua ZHOU XiuJi GOU XiaoHu ZHAO Ping FAN ZeXin Samuli HELAMA | 2012 | Science China Earth Sciences2012，55，5： | 7 |
| 6 | New quaternary sequences of even length with optimal auto-correlation显示文摘Sequences with low auto-correlation property have been applied in code-division multiple access communication systems, radar and cryptography. Using the inverse Gray mapping, a quaternary sequence of even length N can be obtained from two binary sequences of the same length, which are called component sequences. In this paper, using interleaving method, we present several classes of component sequences from twin-prime sequences pairs or GMW sequences pairs given by Tang and Ding in 2010; or two, three or four binary sequences defined by cyclotomic classes of order 4. Hence we can obtain new classes of quaternary sequences, which are different from known ones, since known component sequences are constructed from a pair of binary sequences with optimal auto-correlation or Sidel'nikov sequences. | Wei SU Yang YANG Zhengchun ZHOU Xiaohu TANG | 2018 | Science China(Information Sciences)2018，61，2： | 4 |
| 7 | Relay camera videometrics based conversion method for unstable platform to static reference显示文摘This article proposes a relay camera videometrics based method to convert an unstable measuring platform to a static reference to solve the problems of large error or invalidation caused by measuring platform instability in photogrammetric and videometric measurements.The method installs a relay camera on the unstable platform and captures images of a reference marker fixed on a static reference or vice versa to resolve the 3D movement of the unstable platform relative to the static reference,based on which it corrects the error of the measured results and thus eliminating the influence of the platform movement.It finds new and important applications for videometrics by making high-precision dynamic measurement possible on unstable platforms.Verification experiments and numerical simulations have proven its validity and practicability. | YU QiFeng SUN XiangYi JIANG GuangWen LIU XiaoLin ZHANG XiaoHu ZHOU Jian SHANG Yang | 2011 | Science China(Technological Sciences)2011，54，4： | 4 |
| 8 | Study of risk acceptance criteria for dams显示文摘This paper discusses the methods of establishing risk criteria for dams and reviews the application of dam risk criteria for individuals and societies in different countries or districts.Given the conditions in China and considering the public safety and acceptance of dam risk,historical dam break data and current design standards,individual and societal risk criteria for dams are proposed.The tolerable dam risk criteria for individuals should be set to 10-5–10-7 per annum based on project scale,for example,approximately 1.0×10-7 per annum,which corresponds to a reliability index of 4.2 based on a 100-year lifespan for a first-class or large project.The societal limit for risk tolerance for dams should be set to approximately 10-3–10-5 per annum,corresponding to the fatality range from 1 to 100 and be horizontally extended to 1000,and F-N curves are proposed.It was also found that the reliability indices of Chinese Standard(GB 50199-2013)and Eurocode1(2002)are different,but they have the same level of safety measured by the annual probability of failure.The research results have significance for establishing dam risk criteria. | LI ShouYi ZHOU XingBo WANG YuJie ZHOU JianPing DU XiaoHu CHEN ZuYu | 2015 | Science China(Technological Sciences)2015，58，7： | 3 |
| 9 | A comprehensive analysis of the Bencao(herbal)small RNA Atlas reveals novel RNA therapeutics for treating human diseases显示文摘Cross-kingdom herbal mi RNA was first reported in 2012.Using a modified herbal extraction protocol,we obtained 73,677,287sequences by RNA-seq from 245 traditional Chinese Medicine(TCM),of which 20,758,257 were unique sequences.We constructed a Bencao(herbal)small RNA(s RNA)Atlas(http://gffzz4a3adbfa122d4a47hu55uk6cqubwc6f9u.ffgz.tsg.suse.edu.cn),annotated the sequences by sequence-based clustering,and created a nomenclature system for Bencao s RNAs.The profiles of 21,757 mi RNAs in the Atlas were highly consistent with those of plant mi RNAs in mi RBase.Using software tools,our results demonstrated that all human genes might be regulated by s RNAs from the Bencao s RNA Atlas,part of the predicted human target genes were experimentally validated,suggesting that Bencao s RNAs might be one of the main bioactive components of herbal medicines.We established roadmaps for oligonucleotide drugs development and optimization of TCM prescriptions.Moreover,the decoctosome,a lipo-nano particle consisting of 0.5%–2.5%of the decoction,demonstrated potent medical effects.We propose a Bencao(herbal)Index,including small-molecule compounds(SM),protein peptides(P),nucleic acid(N),non-nucleic and non-proteinogenic large-molecule compounds(LM)and elements from Mendeleev's periodic table(E),to quantitatively measure the medical effects of botanic medicine.The Bencao s RNA Atlas is a resource for developing gene-targeting oligonucleotide drugs and optimizing botanical medicine,and may provide potential remedies for the theory and practice of one medicine. | Yinghao Cao Yexuan Lin Na Sun Xinyi Du Yixin Dong Song Mei Xingyu Deng Xiaobei Li Shaoting Guo Kegong Tang Jiaqi Liu Xiangyu Qiao Dandan Zhao Yuhao Qin Cong Zhang Tianyi Xin Xiaohu Shi Congzhao Zhou Tao Dong De-an Guo Benedikt MKessler Dong Xu Jingyuan Song Fengming Huang Xiaoyue Wang Chengyu Jiang | 2023 | Science China(Life Sciences)2023，66，10： | 2 |
| 10 | Two-Year Observation of Fossil Fuel Carbon Dioxide Spatial Distribution in Xi’an City显示文摘The need for atmospheric carbon dioxide(CO2)reduction in the context of global warming is widely acknowledged by the global scientific community.Fossil fuel CO2(CO2ff)emissions occur mainly in cities,and can be monitored directly with radiocarbon(14 C).In this research,annual plants[Setaria viridis(L.)Beauv.]were collected from 26 sites in 2013 and2014 in the central urban district of Xi’an City.The△14C content of the samples were analyzed using a 3 MV Accelerator Mass Spectrometer,and CO2ff concentrations were calculated based on mass balance equations.The results showed that the CO2ff mixing ratio ranged from 15.9 to 25.0 ppm(part per million,equivalent toμmol mol-1),with an average of 20.5 ppm in 2013.The range of measured values became larger in 2014,from 13.9 ppm to 33.1 ppm,with an average of 23.5 ppm.The differences among the average CO2ff concentrations between the central area and outer urban areas were not statistically significant.Although the year-to-year variation of the CO2ff concentration was significant(P<0.01),there was a distinctly low CO2 ff value observed in the northeast corner of the city.CO2 ff emiissions from vehicle exhaust and residential sources appeared to be more significant than two thermal power plants,according to our observed CO2 ff spatial distribution.The variation of pollution source transport recorded in our observations was likely controlled by southwesterly winds.These results could assist in the optimal placement of regional CO2 monitoring stations,and benefit the local government in the implementation of efficient carbon emission reduction measures. | Xiaohu XIONG Weijian ZHOU Shugang WU Peng CHENG Hua DU Yaoyao HOU Zhenchuan NIU Peng WANG Xuefeng LU Yunchong FU | 2020 | Advances in Atmospheric Sciences2020，37，6： | 2 |
| 11 | Multifaceted functions of STING in human health and disease:from molecular mechanism to targeted strategy显示文摘Since the discovery of Stimulator of Interferon Genes(STING)as an important pivot for cytosolic DNA sensation and interferon(IFN)induction,intensive efforts have been endeavored to clarify the molecular mechanism of its activation,its physiological function as a ubiquitously expressed protein,and to explore its potential as a therapeutic target in a wide range of immune-related diseases.With its orthodox ligand 2’3’-cyclic GMP–AMP(2’3’-cGAMP)and the upstream sensor 2’3’-cGAMP synthase(cGAS)to be found,STING acquires its central functionality in the best-studied signaling cascade,namely the cGAS–STING–IFN pathway.However,recently updated research through structural research,genetic screening,and biochemical assay greatly extends the current knowledge of STING biology.A second ligand pocket was recently discovered in the transmembrane domain for a synthetic agonist.On its downstream outputs,accumulating studies sketch primordial and multifaceted roles of STING beyond its cytokine-inducing function,such as autophagy,cell death,metabolic modulation,endoplasmic reticulum(ER)stress,and RNA virus restriction.Furthermore,with the expansion of the STING interactome,the details of STING trafficking also get clearer.After retrospecting the brief history of viral interference and the milestone events since the discovery of STING,we present a vivid panorama of STING biology taking into account the details of the biochemical assay and structural information,especially its versatile outputs and functions beyond IFN induction.We also summarize the roles of STING in the pathogenesis of various diseases and highlight the development of small-molecular compounds targeting STING for disease treatment in combination with the latest research.Finally,we discuss the open questions imperative to answer. | Zili Zhang Haifeng Zhou Xiaohu Ouyang Yalan Dong Alexey Sarapultsev Shanshan Luo Desheng Hu | 2023 | Signal Transduction and Targeted Therapy2023，8，1： | 2 |
| 12 | Facile Li-Al layered double hydroxide films on Al alloy for enhanced hydrophobicity, anti-biofouling and anti-corrosion performance显示文摘In this work,lithium(Li)-aluminum(Al)layered double hydroxide(LDH)films modified by 4-amino-2-((hydrazine methylene)amino)-4-oxobutanoic acid(denoted as AOA acid)and/or 1H,1H,2H,2H-perfluorooctyltriethoxysilane were prepared on 6N01 Al alloy by a facile,in-situ growth method with enhanced hydrophobicity,anti-biofouling and anti-corrosion performance.The preparation is low energy consumptive and environment friendly,relying on self-assembly at ambient temperature.The structure,molecular weight and functional groups of the synthesized AOA acid were characterized by NMR spectrometer,ESI-MS spectrometer and Fourier transform infrared(FT-IR)spectroscopy.And the compositions,structure and morphology of the films were characterized by Fourier transform infrared(FT-IR)spectroscopy,glancing-angle X-ray diffraction(GA-XRD),X-ray photoelectron spectroscopy(XPS),field emission scanning electron microscopy(FE-SEM)and energy-dispersive x-ray spectrum(EDS).Water contact angle measurements(CA)and atomic force microscopy(AFM)characterization show that the films possess a micro/nanostructure with an improved hydrophobicity.Immersion test,neutral salt tests(NSS)and electrochemical impedance spectroscopy(EIS)conducted in 3.5 wt.%NaCl solutions demonstrate the improved corrosion resistance of the films over bare Al alloy.Meanwhile,the films also possess an excellent anti-bacterial property toEscherichia coli,Bacillus subtilis and sulfate-reducing bacteria. | Ji Li Tianci Yuan Chengliang Zhou Bo Chen Yi Shuai Dawang Wu Dongchu Chen Xiaohu Luo Y.Frank Cheng Yali Liu | 2021 | Journal of Materials Science & Technology2021，，20： | 2 |
| 13 | Flat multifunctional liquid crystal elements through multi-dimensional information multiplexing显示文摘Flat optical elements have attracted enormous attentions and act as promising candidates for the next generation of optical components.As one of the most outstanding representatives,liquid crystal(LC)has been widely applied in flat panel display industries and inspires the wavefront modulation with the development of LC alignment techniques.However,most LC elements perform only one type of optical manipulation and are difficult to realize the multifunctionality and light integration.Here,flat multifunctional liquid crystal elements(FMLCEs),merely composed of anisotropic LC molecules with space-variant orientations,are presented for multichannel information manipulation by means of polarization,space and wavelength multiplexing.Specifically,benefiting from the unique light response with the change of the incident polarization,observation plane,and working wavelength,a series of FMLCEs are demonstrated to achieve distinct near-and far-field display functions.The proposed strategy takes full advantage of basic optical parameters as the decrypted keys to improve the information capacity and security,and we expect it to find potential applications in information encryption,optical anti-counterfeiting,virtual/augmented reality,etc. | Dongliang Tang Zhenglong Shao Xin Xie Yingjie Zhou Xiaohu Zhang Fan Fan Shuangchun Wen | 2023 | Opto-Electronic Advances2023，6，4： | 2 |
| 14 | New Classes of Frequency-Hopping Sequences With Optimal Partial Correlation显示文摘 | Zhengchun Zhou Xiaohu Tang Xianhua Niu Udaya Parampalli | | 0，，01： | 1 |
| 15 | A new class of sequences with zero or low correlation zone based on interleaving technique显示文摘 | ZHOU Zhengchun TANG Xiaohu GONG Guang | 2008 | IEEE Transactions on Information Theory2008，54，9： | 1 |
| 16 | A flexible method for multi-view point clouds alignment of small-size object 显示文摘 | Zhou Langming Zhang Xiaohu Guan Banglei | 2014 | Measurement2014，，58： | 1 |
| 17 | A polymer electrolyte with a thermally induced interfacial ion-blocking function enables safety-enhanced lithium metal batteries显示文摘Lithium metal batteries(LMBs)have recently been revitalized as one of the most promising electrochemical energy storage systems,owing to the ultrahigh specific capacity(3860 mAh g^(-1))and ultralow potential(-3.04 V vs.standard hydrogen electrode)of lithium metal anodes.However,safety hazards originating from lithium dendrite growth and pulverization during cycling and thermal stimulation present significant challenges to the practical application of LMBs.To address this issue,we have developed an in situ polymer electrolyte with thermally induced interfacial ion-blocking ability.We demonstrate that the repolymerization and deposition of residual vinylene carbonate in the as-prepared electrolyte under thermal abuse predominantly results in thermally induced ion blocking at the solid electrolyte interface,thus achieving superior LMB safety.The developed polymer electrolyte also yields superior cyclability in LMBs.This design philosophy provides a good paradigm for improving the safety of LMBs. | Huanrui Zhang Lang Huang Hantao Xu Xiaohu Zhang Zhou Chen Chenhui Gao Chenglong Lu Zhi Liu Meifang Jiang Guanglei Cui | 2022 | eScience2022，2，2： | 1 |
| 18 | Ultrasonic-pretreated waste activated sludge hydrolysis and volatile fatty acid accumulation under alkaline conditions: Effect of temperature显示文摘 | Guihua Zhuo Yuanyuan Yan Xuejun Tan Xiaohu Dai Qi Zhou | 2012 | Journal of Biotechnology2012，，1： | 1 |
| 19 | Utopia: load sharing facility for large, heterogeneous distributed computer system显示文摘 | Zhou Songnian Zheng Xiaohu | 1993 | Software-Practice and Experience1993，23，12： | 1 |
| 20 | New classes of frequency-hopping sequences with optimal partial correlation显示文摘 | Zhou Zhengchun Tang Xiaohu | 2012 | IEEE Trans Inf Theory2012，58，1： | 1 |
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