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| 1 | Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's disease progression显示文摘Recently,increasing evidence has suggested the association between gut dysbiosis and Alzheimer's disease(AD)progression,yet the role of gut microbiota in AD pathogenesis remains obscure.Herein,we provide a potential mechanistic link between gut microbiota dysbiosis and neuroinflammation in AD progression.Using AD mouse models,we discovered that,during AD progression,the alteration of gut microbiota composition leads to the peripheral accumulation of phenylalanine and isoleucine,which stimulates the differentiation and proliferation of pro-inflammatory T helper 1(Thl)cells.The brain-infiltrated peripheral Th1 immune cells are associated with the Ml microglia aaivation,contributing to AD-associated neuroinflammation.Importantly,the elevation of phenylalanine and isoleucine concentrations and the increase of Th1 cell frequency in the blood were also observed in two small independent cohorts of patients with mild cognitive impairment(MCI)due to AD.Furthermore,GV-971,a sodium oligomannate that has demonstrated solid and consistent cognition improvement in a phase 3 clinical trial in China,suppresses gut dysbiosis and the associated phenylalanine/isoleucine accumulation,harnesses neuroinflammation and reverses the cognition impairment.Together,our findings highlight the role of gut dysbiosis-promoted neuroinflammation in AD progression and suggest a novel strategy for AD therapy by remodelling the gut microbiota. | Xinyi Wang Guangqiang Sun Teng Feng Jing Zhang Xun Huang Tao Wang Zuoquan Xie Xingkun Chu Jun Yang Huan Wang Shuaishuai Chang Yanxue Gong Lingfei Ruan Guanqun Zhang Siyuan Yan Wen Lian Chen Du Dabing Yang Qingli Zhang Feifei Lin Jia Liu Haiyan Zhang Changrong Ge Shifu Xiao Jian Ding Meiyu Geng | 2019 | Cell Research2019，29，10： | 192 |
| 2 | Photocatalytic Reduction of Nitro Compounds Using TiO2 Photocatalyst by UV and Vis Dye-sensitized Systems显示文摘Nitro 芳香的混合物能 photocatalytically 被简化为在 UV/TiO2/holes scavenger 和 Vis/TiO2/dye-sensitized 系统把 TiO2 用作光催化剂的相应胺芳香的混合物。在 UV/TiO2/holes scavenger 系统,象甲醇那样的反应底层白酒能被用作洞 scavengers,并且在 Vis/TiO2/dye-sensitized 系统,底层白酒能与高选择被氧化到相应的醛。当甲醇被用作洞 scavengers,照明时间是 6 h 时, 87.2%p 硝基甲苯能 photocatalytically 被简化为 p-toluidine。在 Vis/TiO2/dye-sensitized 系统,为硝基苯的 photocatalytic 减小的芳香的白酒的效果比另外的白酒的好。同时,芳香的白酒能容易被氧化,并且相应的醛的生产效率比另外的白酒的那些高。可能的反应机制也被建议。 | Chen, Shifu Zhang, Huaye Yu, Xiaoling Liu, Wei | 2011 | Chinese Journal of Chemistry2011，29，3： | 2 |
| 3 | Synthesis of AgGa1-xInxSe2 Polycrystalline Materials显示文摘AgGa1-xInxSe2 polycrystals were synthesized by the method of mechanical oscillation and temperature oscillation. X-ray diffraction spectra of polycrystal powder are conformable with the JCPDS cards. Lattice constants a and c calculated from the XRD were found to obey Vegard's law. The melting point of AgGa0.8In0.2Se2 obtained by means of differential scanning calorimetry (DSC) is 796.53 ℃. The DSC curve also show that there are no other transformation points below the melting point. The results indicate that polycrystalline materials synthesized by the method mentioned above are high-quality and can be used to grow single crystals by the vertical Bridgman technology. | Liu Juan Zhao Beijun Zhu Shifu Huang Yi Zhang Jianjun Zhu Weilin Xu Chengfu Chen Baojun Li Ming He Zhiyu | 2006 | Journal of Rare Earths2006，24，z1： | 2 |
| 4 | Studies on preparation, characterization and activity evaluation of heterostructure In2 O3/In (OH) 3 photocatalyst 显示文摘 | CHEN Shifu YU Xiaoling ZHANG Huaye | 2010 | Jour- nal of Hazardous Materials2010，180，1： | 1 |
| 5 | Discrepancy measures for selecting optimal combination of parameter values in object-based image analysis显示文摘 | Yong Liu Ling Bian Yuhong Meng Huanping Wang Shifu Zhang Yining Yang Xiaomin Shao Bo Wang | 2012 | ISPRS Journal of Photogrammetry and Remote Sensing2012，，： | 1 |
| 6 | Study on the Photocatalytic Activity of p-n Junction Photocatalyst Cu20/TiO2显示文摘 | Chen Shifu Zhang Sujuan Liu Wei | | 0，，07： | 1 |
| 7 | Orbilia blu-menaviensis and its Arthrobotrys anamorph显示文摘 | QIAO Min ZHANG Ying LI Shifu | | 0，，1： | 1 |
| 8 | Discrepancy measures for selecting optimal combination of parameter values in object-based image analysis显示文摘 | Yong Liu Ling Bian Yuhong Meng Huanping Wang Shifu Zhang Yining Yang Xiaomin Shao Bo Wang | 2012 | ISPRS Journal of Photogrammetry and Remote Sensing2012，，： | 1 |
| 9 | Effect of microstructures restoration on high temperature fatigue behavior of DZ125 superalloy显示文摘Combination of hot isostatic pressing(HIP)and rejuvenation heat treatment(RHT)technology was used to restore creep-damaged DZ125 directional solidified superalloy,and the influence of microstructure restoration on high temperature fatigue behavior of the samples was explored.The results show that the HIP+RHT process could effectively heal internal cavities and recover the degradedγ’phase in creep-damaged DZ125 superalloy to cubic particles similar as in as-received sample.After restoration treatment,the stress concentration areas inside the sample eradicated with the healing of the internal cavities,and the fatigue source areas were limited only to near surface than initiating from inside as in the as-received and creep-damaged samples.As a result,the restored sample had higher crack initiation life and lower crack propagation rate compared to as-received and creep damaged samples.The TEM microstructure characterization near fatigue fracture showed that the restoration of the degradedγ’phase eliminated tangled dislocation in creep damaged sample and produced evenly distributed dislocations in theγchannel with short curved line-like morphology,like the as-received sample,which effectively hindered the dislocations movement during subsequent deformation,and strengthen the fatigue resistant of alloy.Therefore,it can be concluded that the HIP-RHT process,through the combined effect of internal cavities healing and the restoration of the degraded microstructures,renders higher high temperature fatigue life than creep-damaged and even higher than as-received DZ125 superalloy. | Shifu Wang Allah Ditta Yi Xu Zheng Zhang | 2021 | Progress in Natural Science:Materials International2021，31，4： | 1 |
| 10 | Production of transgenic maize from bombarded type II callus: Effect of gold particle size and callus morphology on transformation efficiency显示文摘 | Bronwyn R. Frame Hongyi Zhang Suzy M. Cocciolone Lyudmila V. Sidorenko Charles R. Dietrich Sue Ellen Pegg Shifu Zhen Patrick S. Schnable Kan Wang | 2000 | In Vitro Cellular & Developmental Biology - Plant2000，，1： | 1 |
| 11 | Preparation, characterization and activity evaluation of heterojunction ZrTi 2 O 6 /TiO 2 photocatalyst显示文摘 | Chen Shifu Zhang Huaye Yu Xiaoling Liu Wei Wang Junen Liu Qiangchun Chen Lei | 2010 | Materials Chemistry and Physics2010，，： | 1 |
| 12 | Preparation and activity evaluation of p-n junction photocatalyst NiO/TiO2显示文摘 | Chen Shifu Zhang Sujuan Liu Wei | 2008 | Journal of Hazardous Materials2008，155，： | 1 |
| 13 | Discrepancy measures for selecting optimal combination of parameter values in object-based image analysis显示文摘 | Yong Liu Ling Bian Yuhong Meng Huanping Wang Shifu Zhang Yining Yang Xiaomin Shao Bo Wang | 2012 | ISPRS Journal of Photogrammetry and Remote Sensing2012，，： | 1 |
| 14 | Production of transgenic maize from bombarded type II callus: Effect of gold particle size and callus morphology on transformation efficiency显示文摘 | Bronwyn R. Frame Hongyi Zhang Suzy M. Cocciolone Lyudmila V. Sidorenko Charles R. Dietrich Sue Ellen Pegg Shifu Zhen Patrick S. Schnable Kan Wang | 2000 | In Vitro Cellular & Developmental Biology - Plant2000，，1： | 1 |
| 15 | Titanium dioxide mediated photocatalytic degradation of methamidophos in aqueous phase显示文摘 | Liu Wei Chen Shifu Zhao Wei Zhang Sujuan | 2008 | Journal of Hazardous Materials2008，，1： | 1 |
| 16 | X-Ray Measurement of Residual Stress in Plastic Bonded Explosives显示文摘The X-ray diffractive technology was adopted for tentative study of plastic bonded explosive. The datum of some new diffractive peaks in standard PDF cards were added. The effects of strain to interplanar distance and crystal size of the explosive were studied. The results show that grain size of plastic bonded explosive is decreasing with the increasing of the pressure, and the residual stress of the explosive is draw stress. | Yong Zhihua Zhu Shifu Zhao Beijun Chen Jinghua Zhang Weibin Wei Xingwen | 2006 | Journal of Rare Earths2006，24，z1： | 0 |
| 17 | SustainableDevelopmen--The Chinese People’s Choice显示文摘Since the Chinese government set out to transform the country’s economic development model, China’s economy has grown healthier, more sustainable and better adapted to fast, long-term growth. | ZHANG SHIFU WEN YUMIN LI ZONGPIN QIU JIANGHONG MA YIWEN SUN PENGHAO WANG YING | 2013 | China Today2013，62，5： | 0 |
| 18 | Research on Soil Conservation and Improvement Technology in Zhaoyang District显示文摘The environment of tobacco-growing soil directly affects the yield and quality of tobacco leaves.In order to solve problems of tobacco-growing soil degradation,low organic matter content and unbalanced soil nutrient supply and promote sustainable and healthy development of tobacco production,this paper comprehensively discussed conservation and improvement techniques of tobacco-growing soil based on existing problems in Zhaoyang District,aiming to provide reference for tobacco-growing soil conservation. | Jing YANG Shifu ZHONG Liting FANG Wei YAN Shixian PU Dianli MA Wenkai XIA Haohan GONG Mengsheng ZHANG Yeming FU Xia NI | 2024 | Agricultural Biotechnology2024，13，1： | 0 |
| 19 | The Choice Is Sustainable development显示文摘‘China, along with the United States, Europe, India and Japan, will become the five engines of world economic development, forging ahead side by side,' said Justin Yifu Lin, a member of the National Committee of the Chinese People’s Political Consultative Conference (CPPCC) and former Chief Economist of the World Bank. On more than one occasion he expressed confidence that China would | Zhang Shifu Wen Yumin Li zongpin Chou Jianghong Ma Yiwen Sun Penghao Wang Ying | 2013 | Beijing Review2013，56，13： | 0 |
| 20 | Stabilization of Cu/Ni Alloy Nanoparticles with Graphdiyne Enabling Efficient CO_(2) Reduction显示文摘Electrocatalysis has become an attractive strategy for the artificial reduction of CO_(2) to high-value chemicals.However,the design and development of highly selective and stable non-noble metal electrocatalysts that convert CO_(2) to CO are still a challenge.As a new type of two-dimensional carbon material,graphdiyne(GDY),is rarely used to explore the application in carbon dioxide reduction reaction(CO_(2)RR).Therefore,we tried to use GDY as a substrate to stabilize the copper-nickel alloy nanoparticles(NPs)to synthesize Cu/Ni@GDY.Cu/Ni@GDY requires an overpotential(−0.61 V)to 10 mA/cm^(2) for the formation of CO,and it shows better activity than Au and Ag,achieving a higher Faraday efficiency of about 95.2%and high stability of about 26 h at an overpotential(−0.70 V).The electronic interaction between GDY substrate and Cu/Ni alloy NPs and the large specific surface area of GDY is responsible for the high performance. | FU Xinliang ZHU Aonan CHEN Xiaojie ZHANG Shifu WANG Mei YUAN Mingjian | 2021 | Chemical Research in Chinese Universities2021，37，6： | 0 |
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