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| 1 | Novel Recombinant Seneca Valley Virus Isolated from Slaughtered Pigs in Guangdong Province显示文摘Dear Editor,Since the first outbreak in Brazil in 2015,Seneca Valley virus(SVV)associated with porcine idiopathic vesicular disease,has shown increasing geographic distribution.Cases of SVV have been reported from several countries including the United States(US),Colombia,Thailand,Canada,and China(Pasma et al.2008;Zhang et al.2015;Sun et al.2017;Wu et al.2017;Liu et al.2018;Saeng-Chuto et al.2018).SVV was first identified in the US in 2002 and is the only member of the genus Senecavirus in the family Picomaviridae(Hales et al.2008;Leme et al.2017).The SVV genome contains a large open reading frame(ORF)encoding a polyprotein,which is cleaved into various mature viral proteins including the leader protein(L),structural proteins(VP1,VP2,VP3,and VP4),and non-structural proteins(2A,2B,2C,3A,3B,3C,and 3D)(Hales et al 2008).Structural proteins bind to their receptor,anthrax toxin receptor 1,to mediate viral invasion and stimulate specific immunity of the host(Jayawardena et al.2018).Non-structural proteins such as 3C suppress innate immune responses by degrading interferon regulatory factor 3(IRF 3)and IRF7 and inhibit the activation of RIG-1,TBK1,and TRAF3 through deubiquitination(Xue et al 2018). | Jianxin Liu Yunfeng Zha Huizi Li Yanwei Sun Fuguang Wang Rong Lu Zhangyong Ning | 2019 | Virologica Sinica2019，34，6： | 7 |
| 2 | Therapeutic effects of a novel tylophorine analog, NK‐007, on collagen‐induced arthritis through suppressing tumor necrosis factor α production and Th17 cell differentiation显示文摘 | Ti Wen Yangguang Li Meng Wu Xiaolin Sun Xiucong Bao Yuquan Lin Jianlei Hao Lin Han Guangchao Cao Ziwen Wang Yuxiu Liu Zhenzhou Wu Zhangyong Hong Puyue Wang Liqing Zhao Zhanguo Li Qingmin Wang Zhinan Yin | 2012 | Arthritis & Rheumatism2012，，9： | 2 |
| 3 | The closed mappings on k-semistratifiable spaces 显示文摘 | Lin Shou Cai Zhangyong Liu Chuan | 2009 | Houston J Math2009，35，： | 1 |
| 4 | The synthesis and antioxidant activity of the Schiff bases of chitosan and carboxymethyl chitosan显示文摘 | Zhangyong Guo Ronge Xing Song Liu | 2005 | Bioorganic & Medicinal Chemistry Letters2005，15，20： | 1 |
| 5 | Hydroxyl radicals scavenging activity of N-substituted chitosan and quaternized chitosan显示文摘 | Zhangyong Guo Hongying Liu Xiaolin Chen | 2006 | Bioorganic& Medicinal Chemistry Letters2006，16，： | 1 |
| 6 | In vitro and in vivo evaluation of improved EGFR targeting peptide-conjugated phthalocyanine photosensitizers for tumor photodynamic therapy显示文摘Phthalocyanine(Pc) is one of the most promising photosensitizer candidates because of its strong absorption(extinction coefficient ε > 10~5 LmoI ~1 cm^1) at long wavelengths and strong singlet oxygen generation abilities(a singlet oxygen quantum yield of approximately 50%). However, low tumor targeting, low water solubility and a high tendency to aggregate appear to significantly restrict the compound's application in tumor treatment. Conjugating Pc with peptide ligands could be a useful strategy for alleviating these problems. Here, to further optimize the structures of peptide-conjugated zinc Pcs for PDT therapy, we finely tuned the hydrophilicity of the modified Pc aromatic macrocycle with varied length of polyethylene glycol(PEG) and added an extra PEG linker and an extra glutamic acid between the Pc ring and the peptide ligand to reduce the influence of the ligand on the Pc aromatic ring.Among the synthesized conjugates, Pc-3 showed greatly improved targeting towards tumors and abolished inoculated tumors with only a single PDT treatment in a subcutaneous xenograft tumor model,making this approach a promising therapeutic agent for the treatment of cancer. | Qingle Chen Yanhong Ma Jisi Zhao Mei Zhao Wenjing Li Qian Liu Li Xiong Wenjie Wu Zhangyong Hong | 2018 | Chinese Chemical Letters2018，29，7： | 1 |
| 7 | Rheological properties of amorphous poly alpha(APAO)modified asphalt binders显示文摘 | WEI Jianming LIU Zhangyong ZHANG Yuzhen | 2013 | Construction and Building Materials2013，48，： | 1 |
| 8 | Two phases of seasonal stem radius variations of Sabina przewalskii Kom. in northwestern China inferred from sub-diurnal shrinkage and expansion patterns显示文摘 | Zhangyong Wang Bao Yang Annie Deslauriers Chun Qin Minhui He Feng Shi Jingjing Liu | 2012 | Trees2012，，6： | 1 |
| 9 | 4-11 Determination of Target Thickness and Luminosity from Beam Energy Losses at HIRFL-CSRe Internal Target显示文摘The experiments with an internal target at a storage ring have many advantages. However, it is difficult to determine the absolute cross section of a reaction where luminosity cannot be simply established through macroscopic measurements. Here we present an experimental determination of the effective target thickness from the beam energy losses at the internal target in HIRFL-CSRe. The measurements here are expected to provide the accurate target thickness and luminosity for the absolute cross-section study on future internal target experiments, and also provide some reference values for the study of beam loss mechanism of the heavy ion at HIRFL-CSRe. | Shao Caojie Yu DeYang Lu Rongchun Xue Yingli Wang Wei Yang Bian Zhang Mingwu Liu Junliang Song Zhangyong Cai Xiaohong | 2015 | IMP & HIRFL Annual Report2015，，1： | 0 |
| 10 | Study of Characteristic LX-ray Spectra of Thick and Thin Au Target by Carbon Ions显示文摘 | Song Zhangyong Yang Zhihu Ruan Fangfang Cai Xiaohong Zhang Hongqiang Shao Jianxiong Cui Ying Xie Jiangshan Gao Zhimin Du Juan Liu Liewen | 2006 | 近代物理研究所和兰州重离子加速器实验室年报:英文版2006，，1： | 0 |
| 11 | 4-18 Single and Double Electron Capture by Fast Xe54+ from Kr and Xe显示文摘When an energetic highly charged ion (HCI) collides with an atom, the target electrons may be captured by theprojectile ion, either radiatively or non-radiatively. During a radiative electron capture (REC), a target electronis transferred to the projectile accompanying with a photon emission, which carries away the excess energy andmomentum. During a non-radiative electron capture (NRC), the energy and momentum conservations are ensuredby the target nucleus[1]. If the captured electrons are populated in excited states, photons maybe emitted duringthe following stabilization processes, and therefore the X-ray spectrum can provide information about the initialpopulation. However, if a solid target is employed, the single-collision condition cannot be ensured when consideringthe capture processes, as well as strong background will be produced[2]. With the development of heavy ioncooling storage rings, the experimental luminance is enhanced by the strong ion beams when a gaseous target isprerequisite[3]. | Yu Deyang Shao Caojie Lu Rongchun Wang Wei Liu Junliang Xue Yingli Song Zhangyong Zhang Mingwu Yang Bian Ruan Fangfang Cai Xiaohong | 2014 | IMP & HIRFL Annual Report2014，，1： | 0 |
| 12 | 4-19 Double K-shell Ionization of Kr Induced by Swift Xe54+ Ions显示文摘Double K-shell ionization of atoms by collisions with charged ions is one of typical two-electron processes andattracts considerable attention both in term of basic theory and experiment. Radiative de-excitation of the doubleK-shell vacancy states of atoms leads to the emission of so called K X-ray hyper-satellites (Kh,Kh . . . )[1], whichgives us the insight into the decay modes of multiply ionized ions as well as the ionization processes during ion-atomcollisions. Contrary to the long-winded and difficult experiments with heavy target due to the low detection efficiencyof K X-ray hyper-satellites with crystal spectrometers[2??4], the bulk of knowledge concerning double K-shellionization in ion-atom collisions has been obtained for light target. | Shao Caojie Yu Deyang Wang Wei Xue Yingli Zhang Mingwu Yang Bian Song Zhangyong Lu Rongchun Liu Junliang Cai Xiaohong | 2014 | IMP & HIRFL Annual Report2014，，1： | 0 |
| 13 | 以自组织方式实现快速离子导向显示文摘Although great attention has been paid to study the guiding effects of charged ions through insulating nanocapillaries or a single microcapillary[1]since the pioneering work of Stolterfoht et al.in 2002[2],the same high standard of reproducibility and accuracy among different laboratory cannot be expected because the bulk and surface conductivities of an insulating material are often not well characterized and depend strongly on the working conditions.In other words,the guiding processes are rather random than controllable.In addition,with the energy increasing,the incomplete guiding effect[3;4]limits the application of guiding a swift ion beam in a self-organizing way. | Xue Yingli Yu Deyang Liu Junliang Zhang Mingwu Song Xiaoxun Hui Xinfei Yang Bian Shao Caojie Song Zhangyong Wang Wei Cai Xiaohong | 2018 | IMP & HIRFL Annual Report2018，，1： | 0 |
| 14 | Angular Distribution of Lyman-1 Transition Following Nonradiative Electron Capture into Xe^53+Ions显示文摘Radiative electron capture(REC)and nonradiative capture(NRC)are two competing mechanisms in relativistic collisions of highly charged ions with atoms[1].REC means electron transfer from target to projectile with the emission of one photon for satisfying energy and momentum conservation laws. | Yang Bian Yu Deyang Cai Xiaohong Shao Caojie Xue Yingli Wang Wei Zhang Mingwu Liu Junliang Song Zhangyong Wu Yehong Lu Rongchun Ruan Fangfang | 2019 | IMP & HIRFL Annual Report2019，，1： | 0 |
| 15 | 基于HOPG的广角高效X射线晶体谱仪显示文摘In collisions between fast heavy ions and atoms,the strong Coulomb field of one of collision partners can cause inner-shell multiple-ionization of the second one[1].The high-resolution measurements of emitted X-rays in the collision are one of the most effective methods to study the multivacancy configurations in atoms or ions as well as the dynamics of the multiple ionization process.The energy shifts of X-rays from states with different vacancy configuration could be large[2].For example,the energy of the argon K hypersatellite and satellite line is between 2.9 and 3.8 keV,and the energy shift causing by per L hole is close to 20 eV[3].In order to simultaneous detection of the emitted X-rays over a wide energy range,thus avoiding the problem of changing the angle of crystal and position of the CCD in one collision system,a wide-angle and high-efficiency X-ray spectrometer based on flat HOPG(Highly Oriented Pyrolytic Graphite)crystal was developed.Due to X-ray from multi-ionized atoms. | Shao Caojie Yu Deyang Wang Wei Yang Bian Liu Junliang Xue Yingli Zhang Mingwu Song Zhangyong Cai Xiaohong | 2018 | IMP & HIRFL Annual Report2018，，1： | 0 |
| 16 | 离子与不同气体靶原子碰撞中的K壳双电离研究显示文摘In collisions between energetic heavy ions and atoms,the strong Coulomb field of one of collision partners can cause double K-shell ionization of the second one.In previous work we have studied the mechanism of double K-shell ionization in krypton atom by bare xenon under different perturbation strengths κ=Zp/vp,where Zp is the charge of the projectile and vp is its velocity in atomic units.The measured double-to-single K-shell ionization cross-section ratio is proportional to the perturbation strengthin the rough region of κ<1,but shows less rapidly increasing when κ>1[1].In order to further investigate such process in a wide rang of perturbation strength,an experiment focusing on K-shell ionization of ions was carried out at HIRFL-CSR in 2017.Ni19+ions with a energy of 95 MeV/u were stored in CSRe to interact with hydrogen,argon,krypton and xenon target,respectively.The X rays produced in collisions of the ions with the target were detected by two Silicon Drift Detectors(SDD)mounted at 35◦and 60◦observation angles with respect to the ion beam direction. | Shao Caojie Yu Deyang Wang Wei Yang Bian Liu Junliang Xue Yingli Zhang Mingwu Song Zhangyong Cai Xiaohong | 2017 | IMP & HIRFL Annual Report2017，，1： | 0 |
| 17 | 50-200 MeV/u全裸氙离子与氪、氙气体靶碰撞的电子俘获及辐射退激发显示文摘In collisions between energetic highly charged ions and atoms,the ions could remove the electrons of the target atoms,or be excited into high-level states.In the first case,the target electrons not only be captured into ground and excited states of the projectile ions,but also be ionized to free.Non-radiative capture(NRC)and radiative electron capture(REC)are two competing mechanisms in fast collisions[1].NRC means electron transfer from a bound state of the target to a bound states of the projectile without the emission of radiation;REC is produced with simultaneous the emission of photon for satisfying energy and momentum conservation laws.The physical essence is the competition between the“electron-nucleus”interaction and the“electron-vacuum”interaction.NRC is dominant in collisions of high-Z ions with heavy target atoms at moderate energies.REC entirely determine the electron capture channel for high collision velocities and light targets[1].Measuring the relative strength of the projectile x-ray emission associated with electron capture could determine state-selective population,angular distribution of single capture Ly 1 or double capture Kα1 and Kα2,would provide new detailed information on the dynamics of ion-atom collisions and atomic structure studies[1]. | Yang Bian Yu Deyang Cai Xiaohong Xue Yingli Shao Caojie Wang Wei Liu Junliang Zhang Mingwu Song Zhangyong Wu Yehong Lu Rongchun Ruan Fangfang | 2017 | IMP & HIRFL Annual Report2017，，1： | 0 |
| 18 | Changes in paddy cropping system enhanced economic profit and ecological sustainability in central China显示文摘In China,the traditional early and late season double rice(DR)system is declining accompanied by the fast increase of two newly developed cropping systems:ratoon rice(RR)and rice-crawfish(RC).Three methodologies:economic analysis,emergy evaluation and life cycle assessment(LCA)were employed to evaluate the economics and sustainability of this paddy cropping system change.Economic analysis indicated that the income and profit of the RC system were far larger than those of RR and DR.The income to costs ratio of RR and RC increased by 25.5 and 122.7%compared with that of DR,respectively.RC had the highest emergy input thanks to increasing irrigation water,electricity,juvenile crawfish and forage input while RR showed a lower total emergy and nonrenewable emergy input,such as irrigation water,electricity,fertilizers and pesticides than DR.The environmental loading ratios decreased by 16.7-50.4%when cropping system changed from DR to RR or from DR to RC while the emergy sustainability indexes increased by 22.6-112.9%.The life cycle assessment indicated lower potential environmental impacts of RR and RC,whose total environmental impact indexes were 35.0-61.0%lower than that of DR.Grain yield of RR was comparable with that of DR in spite of less financial and emergy input of RR,but RC had a much lower grain yield(a 53.6%reduction compared to DR).These results suggested that RR is a suitable cropping system to achieve the food security,economic and environmental goals. | ZHOU Yong YAN Xiao-yuan GONG Song-ling LI Cheng-wei ZHU Rong ZHU Bo LIU Zhangyong WANG Xiao-long CAO Peng | 2022 | Journal of Integrative Agriculture2022，21，2： | 0 |
| 19 | Alum colloid encapsulated insideβ-glucan particles enhance humoral and CTL immune responses of MUC1 vaccine显示文摘We have developed a MUC1 antigen-based antitumor vaccine loaded on alum colloid encapsulated insideβ-glucan particles(GP-Al).The constructed vaccine induced strong MUC1 antigen specific Ig G antibody titers and enhanced CD^(8+)T cells cytotoxic effect to kill tumor cells.These results indicated that GP-Al can be served as an efficient delivery system and adjuvant for the development of cancer vaccines especially small molecule antigens based cancer vaccines. | Yonghui Liu Mingjing Li Haomiao Zhu Zhe Jing Xiaona Yin Kun Wang Zhangyong Hong Wei Zhao | 2021 | Chinese Chemical Letters2021，32，6： | 0 |
| 20 | Synthesis of Special Morphology ZnO Materials and the Performance for Reaction Adsorption Desulfurization of Thiophene显示文摘 | Jingcheng Zhang Jun Nan Zhangyong Liu Haibin Yu Shan Geng Yulin Shi Xiaolong Qu Chenguang Liu Hongguang Liu | 2013 | 应用物理前沿(中英文版)2013，1，1： | 0 |
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