|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Magnetostratigraphy and paleoenvironmental record of Tertiary deposits of Lanzhou Basin显示文摘The Tertiary deposits of the Yongdeng section, the Lanzhou Basin were studied by means of magnetostrati-graphy. The magnetostratigraphic sequences from Paleocene to Miocene were established, and the time scale for the corresponding stratigraphy and mammalian faunas was also established by referring to their correlation to the GPTS of BKSA95 (The geomagnetic polarity time scale which was thoroughly revised and updated by Berggreen et al. in 1995). In the end the paleoenvironmental records and their relationship with the uplifting of the Tibetan Plateau were discussed. The results are as follows. The top boundary of the Xiliugou Formation is dated to be 51 Ma, i.e. Eocene. TheYehucheng Formation covers the time span of 51-31.5 Ma, i.e. from late Early Eocene to early Early Oligocene. The Xianshuihe Formation covers the time span of 31.5-15 Ma, i.e. from Early Oligocene to Middle Miocene. The lower member of the Xianshuihe Formation spans from 31.5 to 20.0 Ma, i.e. from Early Oligocene to early Early | YUE Leping F.Heller QIU Zhanxiang ZHANG Li XIE Guangpu QIU Zhuding ZHANG Yunxiang | 2001 | Chinese Science Bulletin2001，46，9： | 28 |
| 2 | An overview of the use of plastic-film mulching in China to increase crop yield and water-use efficiency显示文摘Since 1990,crop yields have stagnated in many parts of the world,posing a significant challenge to global food security[1].As such;innovative solutions are needed to increase the resource-use efficiency of cropping systems to produce more grains per unit area. | Dongbao Sun Haigang Li Enli Wang Wenqing He Weiping Hao Changrong Yan Yuzhong Li Xurong Mei Yanqing Zhang Zhanxiang Sun Zhikuan Jia Huaiping Zhou Tinglu Fan Xucheng Zhang Qin Liu Fengju Wang Chaochun Zhang Jianbo Shen Qingsuo Wang Fusuo Zhang | 2020 | National Science Review2020，7，10： | 19 |
| 3 | Efficient Gene Targeting in Zebrafish Mediated by a Zebrafish-Codon-Optimized Cas9 and Evaluation of Off-Targeting Effect显示文摘Targeted genome modifications with the Cas9/gRNA system derived from the clustered regularly interspaced short palindromic repeat/CRISPR-associated(CRISPR/Cas)system have been successfully used in cultured human cells as well as in most model organisms,including zebrafish(Danio rerio),mouse,and fruit fly(Chang et al.,2013;Cong et al.,2013; | Da Liu Zhanxiang Wang An Xiao Yutian Zhang Wenyuan Li Yao Zu Shaohua Yao Shuo Lin Bo Zhang | 2014 | Journal of Genetics and Genomics2014，41，1： | 18 |
| 4 | Targeting the gut barrier for the treatment of alcoholic liver disease显示文摘Alcohol consumption remains one of the predominant causes of liver disease and liver-related death worldwide.Intriguingly,dysregulation of the gut barrier is a key factor promoting the pathogenesis of alcoholic liver disease(ALD).A functional gut barrier,which consists of a mucus layer,an intact epithelial monolayer and mucosal immune cells,supports nutrient absorption and prevents bacterial penetration.Compromised gut barrier function is associated with the progression of ALD.Indeed,alcohol consumption disrupts the gut barrier,increases gut permeability,and induces bacterial translocation both in ALD patients and in experimental models with ALD.Moreover,alcohol consumption also causes enteric dysbiosis with both numerical and proportional perturbations.Here,we review and discuss mechanisms of alcohol-induced gut barrier dysfunction to better understand the contribution of the gut-liver axis to the pathogenesis of ALD.Unfortunately,there is no effectual Food and Drug Administration-approved treatment for any stage of ALD.Therefore,we conclude with a discussion of potential strategies aimed at restoring the gut barrier in ALD.The principle behind antibiotics,prebiotics,probiotics and fecal microbiota transplants is to restore microbial symbiosis and subsequently gut barrier function.Nutrientbased treatments,such as dietary supplementation with zinc,niacin or fatty acids,have been shown to regulate tight junction expression,reduce intestinal inflammation,and prevent endotoxemia as well as liver injury caused by alcohol in experimental settings.Interestingly,saturated fatty acids may also directly control the gut microbiome.In summary,clinical and experimental studies highlight the significance and efficacy of the gut barrier in treating ALD. | Zhanxiang Zhou Wei Zhong | 2017 | Liver Research2017，1，4： | 10 |
| 5 | Alterations of the gut microbiome and metabolome in alcoholic liver disease显示文摘Alcohol consumption is one of the leading causes of liver diseases and liver-related death worldwide. The gut is a habitat for billions of microorganisms which promotes metabolism and digestion in their symbiotic relationship with the host. Alterations of gut microbiome by alcohol consumption are referred to bacterial overgrowth, release of bacteria-derived products, and/or changed microbiota equilibrium. Alcohol consumption also perturbs the function of gastrointestinal mucosa and elicits a pathophysiological condition. These adverse effects caused by alcohol may ultimately result in a broad change of gastrointestinal luminal metabolites such as bile acids, short chain fatty acids, and branched chain amino acids. Gut microbiota alterations, metabolic changes produced in a dysbiotic intestinal environment, and the host factors are all critical contributors to the development and progression of alcoholic liver disease. This review summarizes recent findings of how alcohol-induced alterations of gut microbiota and metabolome, and discusses the mecha-nistic link between gastrointestinal dyshomeostasis and alcoholic liver injury. | Wei Zhong Zhanxiang Zhou | 2014 | World Journal of Gastrointestinal Pathophysiology2014，5，4： | 6 |
| 6 | Three-dimensional inversion of borehole-surface electrical data based on quasi-analytical approximation显示文摘地上凿穿表面的 3D 倒置为复杂 geo 电的模型的电的数据仍然是在地球物理的探索的一个挑战性的问题。我们为 3D 倒置开发了一个节目到地上凿穿表面电的数据基于伪分析的近似(质量保证) 并且 re 加权调整结合坡度方法(RRCG ) 用视觉 Fortran 6.5 的算法。到向前当模特儿和 Frechet 衍生物计算的 QA 近似的申请戏剧性地加快计算。为理论模型的合成数据的试用计算证明程序快、高度精确。 | Wang Zhigang He Zhanxiang Liu Haiying | 2006 | Applied Geophysics2006，3，3： | 5 |
| 7 | LIGHT INTERCEPTION AND USE EFFICIENCY DIFFER WITH MAIZE PLANT DENSITY IN MAIZE-PEANUT INTERCROPPING显示文摘Intercropping increases crop yields by optimizing light interception and/or use efficiency.Although intercropping combinations and metrics have been reported,the effects of plant density on light use are not well documented.Here,we examined the light interception and use efficiency in maize-peanut intercropping with different maize plant densities in two row configurations in semiarid dryland agriculture over a two-year period.The field experiment comprised four cropping systems,i.e.,monocropped maize,monocropped peanut,maize-peanut intercropping with two rows of maize and four rows of peanut,intercropping with four rows of maize and four rows of peanut,and three maize plant densities(3.0,4.5 and 6.0 plants m^(-1) row)in both monocropped and intercropping maize.The mean total light interception in intercropping across years and densities was 779 MJ·m^(-2),5.5%higher than in monocropped peanut(737 MJ·m^(-2))and 7.6%lower than in monocropped maize(843 MJ·m^(-2)).Increasing maize density increased light interception in monocropped maize but did not affect the total light interception in the intercrops.Across years the LUE of maize was 2.9 g·MJ–1 and was not affected by cropping system but increased with maize plant density.The LUE of peanut was enhanced in intercropping,especially in a wetter year.The yield advantage of maize-peanut intercropping resulted mainly from the LUE of peanut.These results will help to optimize agronomic management and system design and provide evidence for system level light use efficiency in intercropping. | Qi WANG Zhanxiang SUN Wei BAI Dongsheng ZHANG Yue ZHANG Ruonan WANG Wopke VAN DER WERF Jochem B.EVERS Tjeerd-Jan STOMPH Jianping GUO Lizhen ZHANG | 2021 | Frontiers of Agricultural Science and Engineering2021，8，3： | 4 |
| 8 | The application of the high-frequency electromagnetic sounding method in the exploration of underground thermal water显示文摘高周波的电磁的发出声音作为地来源是用自然的高周波的电磁的地的一个电磁的探索方法。它比直接当前的方法有更高的分辨率和更大的深度穿入并且为地热的精力探索是特别合适的并且低 -- 并且中间水平的地下水察觉。我们介绍为评估地热的水资源的高周波的电磁的发出声音的成功的应用。高频率电磁的系统(有到 1 Hz 的从 10 KHz 的一个频率范围的 MT-U5A ) 首先被使用从中国取样域数据。一个遥远的参考车站被用来保证取样的数据质量。我们然后执行 2D 倒置图象与电的方法数据处理。结果基本上显示地下的地热的水的空间分发并且提供有利线索给在这个区域发现表面下的地热的水的来源。 | Cao Hui He Lanfang He Zhanxiang Zhao Xiaoming | 2006 | Applied Geophysics2006，3，4： | 4 |
| 9 | Aepyosciurinae——a new subfamily of Sciuridae(Rodentia,Mammalia)from basal loess deposits at the northeastern border of Tibetan Plateau显示文摘Aepyosciurinae, a new subfamily of Sciuridae, were found at the base of the early Pleistocene loess deposits in Dongxiang County, Gansu Province. Its unilaterally hyp-sodont and lophodont cheek teeth are unique among the sciurids so far known all over the world. Certain degree of similarity can be observed between the cheek teeth of the new subfamily and the Anomalurinae living in tropical and subtropical forests in central and western Africa. Aepyosci-uris orientalis gen. et sp. nov. might have lived in montaneous woodland or grassland and lived on harder leaves, barks, or even grass. This tends to show that the northeastern border area of the Tibetan Plateau had been lifted considerably high in early Pleistocene (ca. 2 Ma), with drier climate, becoming a suitable habitat for Aepyosciurus orientalis. | WANG Banyue & QIU Zhanxiang Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Beijing 100044, China | 2003 | Chinese Science Bulletin2003，48，7： | 4 |
| 10 | Cryptococcus neoformans,a global threat to human health显示文摘Background Emerging fungal pathogens pose important threats to global public health. The World Health Organization has responded to the rising threat of traditionally neglected fungal infections by developing a Fungal Priority Pathogens List (FPPL). Taking the highest-ranked fungal pathogen in the FPPL,Cryptococcus neoformans, as a paradigm, we review progress made over the past two decades on its global burden, its clinical manifestation and management of cryptococcal infection, and its antifungal resistance. The purpose of this review is to drive research efforts to improve future diagnoses, therapies, and interventions associated with fungal infections.Methods We first reviewed trends in the global burden of HIV-associated cryptococcal infection, mainly based on a series of systematic studies. We next conducted scoping reviews in accordance with the guidelines described in the Preferred Reporting Items for Systematic Reviews and Meta-analyses extension for Scoping Reviews using PubMed and ScienceDirect with the keywordCryptococcus neoformans to identify case reports of cryptococcal infections published since 2000. We then reviewed recent updates on the diagnosis and antifungal treatment of cryptococcal infections. Finally, we summarized knowledge regarding the resistance and tolerance ofC. neoformans to approved antifungal drugs.Results There has been a general reduction in the estimated global burden of HIV-associated cryptococcal meningitis since 2009, probably due to improvements in highly active antiretroviral therapies. However, cryptococcal meningitis still accounts for 19% of AIDS-related deaths annually. The incidences of CM in Europe and North America and the Latin America region have increased by approximately two-fold since 2009, while other regions showed either reduced or stable numbers of cases. Unfortunately, diagnostic and treatment options for cryptococcal infections are limited, and emerging antifungal resistance exacerbates the public health burden.Conclusions The rising threat ofC. neoformans is compounded by accumulating evidence for its ability to infect immunocompetent individuals and the emergence of antifungal-resistant variants. Emphasis should be placed on further understanding the mechanisms of pathogenicity and of antifungal resistance and tolerance. The development of novel management strategies through the identification of new drug targets and the discovery and optimization of new and existing diagnostics and therapeutics are key to reducing the health burden. | Youbao Zhao Leixin Ye Fujie Zhao Lanyue Zhang Zhenguo Lu Tianxin Chu Siyu Wang Zhanxiang Liu Yukai Sun Min Chen Guojian Liao Chen Ding Yingchun Xu Wanqing Liao Linqi Wang | 2023 | Infectious Diseases of Poverty2023，12，2： | 2 |
| 11 | Ethanol-Induced Apoptosis in Mouse Liver显示文摘 | Zhanxiang Zhou Xiuhua Sun Y. James Kang | 2001 | The American Journal of Pathology2001，，1： | 1 |
| 12 | Seedling defoliation of cereal crops increases peanut growth and yield in an intercropping system显示文摘Intercropping cereals and legumes is practiced widely in the world for improving yields and economic benefits. Shorter legume crops in intercropping are shaded by taller cereals, substantially reducing legume growth and yield. Reducing shade in intercropping by shortening the plant height of cereals by seedling defoliation has been proposed as a practical approach to increase crop yields and land productivity. A two-year field experiment was conducted to investigate the effect of defoliation of cereal crops at seedling stage on the growth and yield of peanut(Arachis hypogaea L.) intercropped with corn(Zea mays L.) or millet(Setaria italica L.). In comparison with non-defoliation controls, defoliation reduced final plant height by 29 cm on average for corn and 18 cm for millet. Photosynthetically active radiation on peanut in intercropping systems with corn or millet intercropping was respectively 27.0% and 22.8% higher than those in controls, significantly improving the light environment of intercropped peanut. Net photosynthetic rates of peanut were on average 25.5% higher in corn and peanut intercropping and 19.6% higher in millet and peanut intercropping than those in non-defoliation controls. Total biomass of intercropped peanut increased owing to increased root growth. Across two years, yield of peanut intercropped with corn was 27.7% and with millet 32.8% higher than those of controls. Defoliation of cereal crops did not affect corn yield but significantly decreased millet yield by 24.5%. Our results suggest that applying seedling defoliation in intercropped corn could increase peanut yield without compromising corn yield in an intercropping system. | Bo Huang Xiaojin Zou Huasen Xu Jiayi Xu Huiyu Liu Wentao Sun Liang Gong Shiwei Niu Liangshan Feng Ning Yang Lizhen Zhang Zhanxiang Sun | 2022 | The Crop Journal2022，10，2： | 1 |
| 13 | Land mammal geochronology and magnetostratigraphy of Mid-Tertiary deposits in the Lanzhou Basin,Gansu Province,China显示文摘 | Qiu Zhanxiang Wangbanyue Qiuzhuding | 2001 | Eclogae Geology Helv2001，94，： | 1 |
| 14 | Plastic film mulching for water-efficient agricultural applications and degradable films materials development research显示文摘 | Yang Ning Sun Zhanxiang Feng Liangshan | | Materials and Manufacturing Processes0，30，2： | 1 |
| 15 | Danghe area (western Gansu, China) biostratigraphy and implications for depositional history and tectonics of northern Tibetan Plateau显示文摘 | Wang Xiaoming Wang Banyue Qiu Zhanxiang Xie Guangpu Xie Junyi Downs W Qiu Zhuding Deng Tao | 2003 | Earth Planet Sci Lett2003，208，34： | 1 |
| 16 | Monoradically luminescent polymers by a super acid-catalyzed polymerization and deep-red electroluminescence显示文摘Luminescent radicals have received great attention recently due to their idiographic luminescent properties and potential 100%utilization efficiency of doublets under electrical excitation.However,luminescent radical polymers are rarely explored owing to their challenging molecular design and synthesis.Herein,we report an efficient approach to construct luminescent radical polymers by a super acid-catalyzed polymerization reaction proceeded at room temperature,which intrinsically avoid the heavy metal catalyst.The obtained polymers exhibit the unique paramagnetic signals,good thermal properties,and excellent photostability.Moreover,the quantifiable electroluminescence of such radical polymers was demonstrated for the first time. | Kebin An Guohua Xie Shaolong Gong Zhanxiang Chen Xiang Zhou Fan Ni Chuluo Yang | 2020 | Science China Chemistry2020，63，9： | 1 |
| 17 | Metallothione in inhibits myocardial apoptosis in copper-deficient mice:role of atrial natriuretic peptide显示文摘 | Kang James Y Zhou Zhanxiang Wu Huiyun | 2000 | Lab Invest2000，80，74： | 1 |
| 18 | Mapping reservoir boundary by borehole-surface显示文摘 | ZHANXIANG HE XUEJUN LIU WEITING QIU | 2005 | TFEM:The Leading Edge2005，24，： | 1 |
| 19 | Identification of serum metabolites enhancing inflammatory responses in COVID-19显示文摘Coronavirus disease 2019(COVID-19),caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),is characterized by a strong production of inflammatory cytokines such as TNF and IL-6,which underlie the severity of the disease.However,the molecular mechanisms responsible for such a strong immune response remains unclear.Here,utilizing targeted tandem mass spectrometry to analyze serum metabolome and lipidome in COVID-19 patients at different temporal stages,we identified that 611 metabolites(of 1,039)were significantly altered in COVID-19 patients.Among them,two metabolites,agmatine and putrescine,were prominently elevated in the serum of patients;and 2-quinolinecarboxylate was changed in a biphasic manner,elevated during early COVID-19 infection but levelled off.When tested in mouse embryonic fibroblasts(MEFs)and macrophages,these 3 metabolites were found to activate the NF-κB pathway that plays a pivotal role in governing cytokine production.Importantly,these metabolites were each able to cause strong increase of TNF and IL-6 levels when administered to wildtype mice,but not in the mice lacking NF-κB.Intriguingly,these metabolites have little effects on the activation of interferon regulatory factors(IRFs)for the production of type I interferons(IFNs)for antiviral defenses.These data suggest that circulating metabolites resulting from COVID-19 infection may act as effectors to elicit the peculiar systemic inflammatory responses,exhibiting severely strong proinflammatory cytokine production with limited induction of the interferons.Our study may provide a rationale for development of drugs to alleviate inflammation in COVID-19 patients. | Chen-Song Zhang Bingchang Zhang Mengqi Li Xiaoyan Wei Kai Gong Zhiyong Li Xiangyang Yao Jianfeng Wu Cixiong Zhang Mingxia Zhu Lei Zhang Xiufeng Sun Yi-Hong Zhan Zhengye Jiang Wenpeng Zhao Wei Zhong Xinguo Zhuang Dawang Zhou Hai-Long Piao Sheng-Cai Lin Zhanxiang Wang | 2022 | Science China(Life Sciences)2022，65，10： | 1 |
| 20 | Construction of Ecological Green Space System in Yan'an City,China显示文摘Ecosystem of Yan'an City is being faced with serious problems such as increasing pressure of protecting ecological elements,and contradictions in utilization of ecological spaces.To enhance supervision over regional ecological resources,guide the orderly expansion of urban spaces,construct a stable eco-security pattern for sustainable development of the city,and create an urban environment favorable for living and working,this study follows the principles of 'ecology on the priority,landscape continuity,diversity,optimization of layout,and sustainability'.By analyzing distribution features of ecological resources in Yan'an City,considering rules of its urban space expansion,and studying the 'ring-wedge-network' spatial pattern of its ecological green spaces,this study is to build an ecological network with a complete spatial system,definite ecological zoning and characteristic landscapes in which ecological elements are protected comprehensively,ecological conservation,restoration and construction promoted simultaneously. | HE Hongyun,LI Zhanxiang(Shaanxi Urban and Rural Planning and Designing Academy,Xi’an,Shaanxi 710032,China) | 2012 | Journal of Landscape Research2012，4，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员