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| 1 | Hybrid hierarchy storage system in MilkyWay-2 supercomputer显示文摘 | Weixia XU Yutong LU Qiong LI Enqiang ZHOU Zhenlong SONG Yong DONG Wei ZHANG Dengping WEI Xiaoming ZHANG Haitao CHEN Jianying XING Yuan YUAN | 2014 | Frontiers of Computer Science2014，8，3： | 11 |
| 2 | CO removal by two-stage methanation for polymer electrolyte fuel cell显示文摘为了移开公司完成,降低公司内容在在为聚合物电解质的 reformer 的 CO 移动步的 10 ppm 下面燃料房间(PEFC ) 合作产生系统,在各种各样的条件下面的公司优先的 methanation 在这篇论文被学习。结果证明与催化剂的一种单个类型,到达两公司移动深度和公司 2 变换比率是困难的低于 5% 。因此,使用二种催化剂的一个二阶段的 methanation 过程在这研究被建议,也就是说有相对低的活动的一个种催化剂和为在更高的温度的第一个阶段的高选择,并且有为在更低的温度的第二个阶段的相对高的活动和高选择的另一种催化剂。试验性的结果证明在第一个阶段公司,内容从 1% 被减少到低于 0.1% 在 250 300 ° C,并且在第二个阶段到在在 150 185 ° C 的 10 ppm 下面。公司 2 变换被作为不到 5% 。同时,在公司移动深度上入口公司内容和 GHSV 影响也在这篇论文被讨论。 | Zhiyuan Li Wanliang Mi Juan Gong Zhenlong Lu Lihao Xu Qingquan Su | 2008 | Journal of Natural Gas Chemistry2008，17，4： | 5 |
| 3 | Finite element mesh up- date methods for fluid-structure interaction simulations 显示文摘 | XU Zhenlong ACCORSI M | 2004 | Finite Elements in Analysis and Design2004，40，910： | 1 |
| 4 | Pigeon Robot for Navigation Guided by Remote Control:System Construction and Functional Verification显示文摘Animal robots have outstanding advantages over traditional robots in their own energy supplies,orientation,and natural concealment,delivering significant value in the theories and applications of neural science,national security,and other fields.Presently,many animal robots have been fabricated,but researches about the applications of avian robots are still lacking.In this study,we constructed a Pigeon Robot System(PRS),optimized the electric stimulation parameters,assessed the electric stimulus of navigation,and evaluated the navigation efficiency in the field.Biphasic pulse constant current pattern was adapted,and the optimal stimulus parameters of 4 nuclei tested were of amplitude 0.3 mA,5 pulse trains,frequency 25 Hz,5 pulses,and a 25%duty cycle.Effective ratio of left and right steering behavior response to electric stimulus dorsointermedius ventralis anterior nuclei was 67%and 83%,respectively(mean value 75%).Electrical stimulation efficiency was 0.34-0.68 and path efficiency was 0.72-0.85 among pigeon robot individuals in the open field.Neither electrical stimulation efficiency nor path efficiency differed significantly(P>0.05),suggesting that the navigational PRS performance was not biased in either direction.PRS can achieve continuous navigation along simple pathways and provide the necessary application infrastructure and technical reference for the development of animal robot navigation technology. | Zhengyue Zhou Denghui Liu Hong Sun Wenbo Xu Xinmao Tian Xiaoyuan Li Han Cheng Zhenlong Wang | 2021 | Journal of Bionic Engineering2021，18，1： | 1 |
| 5 | Bioinspired Injectable Self-Healing Hydrogel Sealant with Fault-Tolerant and Repeated Thermo-Responsive Adhesion for Sutureless Post-Wound-Closure and Wound Healing显示文摘Hydrogels with multifunctionalities,including sufficient bonding strength,injectability and self-healing capacity,responsive-adhesive ability,fault-tolerant and repeated tissue adhesion,are urgently demanded for invasive wound closure and wound healing.Motivated by the adhesive mechanism of mussel and brown algae,bioinspired dynamic bonds cross-linked multifunctional hydrogel adhesive is designed based on sodium alginate(SA),gelatin(GT)and protocatechualdehyde,with ferric ions added,for sutureless post-wound-closure.The dynamic hydrogel cross-linked through Schiff base bond,catechol-Fe coordinate bond and the strong interaction between GT with temperature-dependent phase transition and SA,endows the resulting hydrogel with sufficient mechanical and adhesive strength for efficient wound closure,injectability and self-healing capacity,and repeated closure of reopened wounds.Moreover,the temperature-dependent adhesive properties endowed mispositioning hydrogel to be removed/repositioned,which is conducive for the fault-tolerant adhesion of the hydrogel adhesives during surgery.Besides,the hydrogels present good biocompatibility,near-infrared-assisted photothermal antibacterial activity,antioxidation and repeated thermo-responsive reversible adhesion and good hemostatic effect.The in vivo incision closure evaluation demonstrated their capability to promote the post-wound-closure and wound healing of the incisions,indicating that the developed reversible adhesive hydrogel dressing could serve as versatile tissue sealant. | Yuqing Liang Huiru Xu Zhenlong Li Aodi Zhangji Baolin Guo | 2022 | Nano-Micro Letters2022，14，11： | 1 |
| 6 | Correction: Characterization of a small-molecule inhibitor targeting NEMO/IKKβ to suppress colorectal lcancergrowth显示文摘In the process of collating the raw data,the authors noticed an inadvertent mistake occurred in Fig.3b that needs to be corrected after online publication of the article.In Fig.3b,as a result of an error in the graphics panel arrangement process,the band of NEMO was repeatedly inserted asβ-actin by mistake.The correct band is shown as below and in the updated Fig.3b.The correction did not affect any of our results or discussion as present in the original publication.We regret any inconvenience this has caused. | Zhenlong Yu Jian Gao Xiaolei Zhang Yulin Peng Wenlong Wei Jianrong Xu Zhenwei Li Chao Wang Meirong Zhou Xiangge Tian Lei Feng Xiaokui Huo Min Liu Mingliang Ye De-an Guo Xiaochi Ma | 2023 | Signal Transduction and Targeted Therapy2023，8，10： | 0 |
| 7 | Oversample Reconstruction Based on a Strong Inter-Diagonal Matrix for an Optical Microscanning Thermal Microscope Imaging System显示文摘Based on a strong inter-diagonal matrix and Taylor series expansions,an oversample reconstruction method was proposed to calibrate the optical micro-scanning error. The technique can obtain regular 2 ×2 microscanning undersampling images from the real irregular undersampling images,and can then obtain a high spatial oversample resolution image. Simulations and experiments show that the proposed technique can reduce optical micro-scanning error and improve the system's spatial resolution. The algorithm is simple,fast and has low computational complexity. It can also be applied to other electro-optical imaging systems to improve their spatial resolution and has a widespread application prospect. | Meijing Gao Ailing Tan Jie Xu Weiqi Jin Zhenlong Zu Ming Yang | 2018 | Journal of Beijing Institute of Technology2018，27，1： | 0 |
| 8 | Experimental and theoretical analysis of a hybrid vibration energy harvester with integrated piezoelectric and electromagnetic interaction显示文摘Harvesting vibration energy has attracted the attention of researchers in recent decades as a promising approach for powering wireless sensor networks.The hybridization of piezoelectricity and electromagnetism has proven helpful in the improvement of vibration energy harvesting.In this study,we explore the integration of piezoelectric and electromagnetic parts in one vibration energy harvesting device.Lumped-parameter models of the system are derived considering the different connection topologies of the piezoelectric and electromagnetic parts.Numerical predictions from these models are compared with experimental results to throw light on the nonlinearities in the system.Modifications of the system are also explored to provide insights into opportunities to improve its performance and that of future vibration energy harvesters. | Shifan HUANG Weihao LUO Zongming ZHU Zhenlong XU Ban WANG Maoying ZHOU Huawei QIN | 2023 | Journal of Zhejiang University-Science A(Applied Physics & Engineering)2023，24，11： | 0 |
| 9 | Characterization of a small-molecule inhibitor targeting NEMO/IKKβto suppress colorectal cancer growth显示文摘NEMO/IKKβcomplex is a central regulator of NF-κB signaling pathway,its dissociation has been considered to be an attractive therapeutic target.Herein,using a combined strategy of molecular pharmacological phenotyping,proteomics and bioinformatics analysis,Shikonin(SHK)is identified as a potential inhibitor of the IKKβ/NEMO complex.It destabilizes IKKβ/NEMO complex with IC_(50) of 174 nM,thereby significantly impairing the proliferation of colorectal cancer cells by suppressing the NF-κB pathway in vitro and in vivo.In addition,we also elucidated the potential target sites of SHK in the NEMO/IKKβcomplex.Our study provides some new insights for the development of potent small-molecule PPI inhibitors. | Zhenlong Yu Jian Gao Xiaolei Zhang Yulin Peng Wenlong Wei Jianrong Xu Zhenwei Li Chao Wang Meirong Zhou Xiangge Tian Lei Feng Xiaokui Huo Min Liu Mingliang Ye De-an Guo Xiaochi Ma | 2022 | Signal Transduction and Targeted Therapy2022，7，4： | 0 |
| 10 | Amplified visualization and function exploration of exosomal protein-specific glycosylation using hybridization chain reaction from non-functional epitope显示文摘Exosomal glycoproteins play significant roles in many physiological and pathological procedures. However, the current methods for studying exosomal glycoproteins have low sensitivity or can affect exosomal biological function. Herein, we developed a proximity dual-tagging strategy using an induced hybridization chain reaction(HCR) from the target’s non-functional epitope for amplified visualization and functional exploration of exosomal protein-specific glycosylation. This strategy leverages dualtagging based on the aptamer with little influence on target function and metabolic glycan labelling, and the rigid product and high sensitivity of HCR. The method improves the signal of visualizing exosomal PD-L1(exo PD-L1) by 7.7-fold compared with the signal without HCR amplification without affecting the natural exo PD-L1/PD-1 interaction. As a result, we verified that the interaction between exo PD-L1 and PD-1 positive cells is positively correlated to the glycosylation level of exo PD-L1. Overall,we have developed a sensitive method with little functional influence to visualize exosomal protein-specific glycosylation in situ,offering a powerful tool for studying the biological implications of exosomal glycoproteins. | Siyin Kang Lin Zhu Wencheng Wang Yinzhu Lu Zhenlong You Chi Zhang Yuanfeng Xu Chaoyong Yang Yanling Song | 2022 | Science China Chemistry2022，65，6： | 0 |
| 11 | Stratum Griseum Periventriculare-mediated Fear Emotion Regulates Motor Behavior in Pigeons显示文摘A pigeon robot is an ideal experimental animal for research in flying animal robots.The majority of current research publications have entailed electrical stimulation of the motor nuclei to regulate movement forcibly,and although a“virtual fear”behavior model has been proposed,the structure,location,and function of the nuclei that generate fear emotions remain obscure.Previous studies have shown that the Stratum Griseum Periventriculare(SGP)of pigeons is homologous to the mammalian periaqueductal gray(PAG),which plays an essential role in mammalian fear.To reveal the role of fear mediated by the SGP in behavioral regulation,we evaluated the structure and location of the SGP by histologic identification combined with magnetic resonance imaging,and analyzed the behavior of the SGP by electrical stimulation.Finally,the function of the SGP was verified with escape testing and homing experiments in an open field.Our results showed that the SGP is located in the pigeon midbrain and divided into two subregions,the dorsal part of the stratum griseum periventriculare(SGPd)and the ventral part of the stratum griseum periventriculare(SGPv)(the ranges were AP1.5–4.75 mm,ML1.75–6.75 mm,and DV2.2–7.1 mm),and that wired and wireless electrical stimulation freezing was the dominant behavior.In the escape test,SGP electrical stimulation caused the pigeons to flee to a safe place,while in the open-field homing test,electrical stimulation of the SGP induced evasive behavior in pigeons away from their original homing route.These results confirm that the SGP plays a crucial role in fear,and that electrical stimulation of this nucleus induces corresponding fear behaviors. | Wenbo Xu Long Yang Zishi Wang Lifang Yang Han Cheng Shixin Zhu Zhigang Shang Zhenlong Wang | 2023 | Journal of Bionic Engineering2023，20，5： | 0 |
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