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| 1 | TRPV1 activation improves exercise endurance and energy metabolism through PGC-1α upregulation in mice显示文摘 | Zhidan Luo Liqun Ma Zhigang Zhao Hongbo He Dachun Yang Xiaoli Feng Shuangtao Ma Xiaoping Chen Tianqi Zhu Tingbing Cao Daoyan Liu Bernd Nilius Yu Huang Zhencheng Yan Zhiming Zhu | 2012 | Cell Research2012，22，3： | 18 |
| 2 | Petrogenesis and tectonic implications of early Paleozoic granitoids in East Kunlun belt: Evidences from geochronology, geochemistry and isotopes显示文摘The East Kunlun Orogenic Belt(EKOB) provides an important link to reconstruct the evolution of the Proto-Tethys and Paleo-Tethys realm. The EKOB is marked by widespread Early Paleozoic magmatism.Here we report the petrology, bulk geochemistry, zircon Ue Pb dating and, Lue Hf and SreN d isotopic data of the Early Paleozoic granitic rocks in Zhiyu area of the southern EKOB. Based on the zircon U-Pb dating, these granitoids, consisting of diorite, granodiorite and monzogranite, were formed during 450 -430 Ma the Late Ordovician to Middle Silurian. The diorite and granodiorite are high Sr/Y ratio as adakitic affinities, and the monzogranite belongs to highly fractionated I-type. Their(^(87)Sr/^(86)Sr)ivalues range from 0.7059 to 0.7085, εNd(t) values from -1.6 to -6.0 and the zircon εHf(t) values show large variations from +9.1 to -8.6 with Hf model ages(T_(DM2)) about 848 Ma and 1970 Ma. The large variations of whole-rock Nd and zircon Hf isotopes demonstrate strong isotopic heterogeneity of the source regions which probably resulted from multi-phase underplating of mantle-derived magmas. Geochemical and isotopic studies proved that the diorite and granodiorite had been derived from partial melting of heterogeneous crustal source with variable contributions from ancient continental crust and juvenile components, and the monzogranites were representing fractional crystallization and crustal contamination for arc magma. The Early Paleozoic adakitic rocks and high-K calc-alkaline granitoids in the southern EKOB were likely emplaced in a continental marginal arc setting possibly linked to the southwards subduction of the Paleo Kunlun Ocean and the magma generation is linked to partial melting of thickened continental crust induced by underplating of mantle-derived magmas. | Guochen Dong Mingfei Luo Xuanxue Mo Zhidan Zhao Liangqiong Dong Xuehui Yu Xin Wang Xiaowei Li Xiongfei Huang Yanbin Liu | 2018 | Geoscience Frontiers2018，9，5： | 10 |
| 3 | Activation of the cold-sensing TRPM8 channel triggers UCP1-dependent thermogenesis and prevents obesity显示文摘Brown adipose tissue(BAT)is an energy-expending organ that produces heat.Expansion or activation of BAT prevents obesity and diabetes.Chronic cold exposure enhances thermogenesis in BAT through uncoupling protein 1(UCP1)activation triggered via a b-adrenergic pathway.Here,we report that the cold-sensing transient receptor potential melastatin 8(TRPM8)is functionally present in mouse BAT.Challenging brown adipocytes with menthol,a TRPM8 agonist,up-regulates UCP1 expression and requires protein kinase A activation.Upon mimicking long-term cold exposure with chronic dietary menthol application,menthol significantly increased the core temperatures and locomotor activity in wild-type mice;these effects were absent in both TRPM82/2 and UCP12/2 mice.Dietary obesity and glucose abnormalities were also prevented by menthol treatment.Our results reveal a previously unrecognized role for TRPM8,suggesting that stimulation of this channel mediates BAT thermogenesis,which could constitute a promising way to treat obesity. | Shuangtao Ma Hao Yu Zhigang Zhao Zhidan Luo Jing Chen Yinxing Ni Rongbing Jin Liqun Ma Peijian Wang Zhenyu Zhu Li Li Jian Zhong Daoyan Liu Bernd Nilius Zhiming Zhu | 2012 | Journal of Molecular Cell Biology2012，4，2： | 2 |
| 4 | Atorvastatin Attenuates TNF-α–induced Increase of Glucose Oxidation Through PGC-1α Upregulation in Cardiomyocytes显示文摘 | Feng Gao Yinxing Ni Zhidan Luo Yi Liang Zhencheng Yan Xingsen Xu Daoyan Liu Jiang Wang Shanjun Zhu Zhiming Zhu | 2012 | Journal of Cardiovascular Pharmacology2012，，6： | 1 |
| 5 | Activation of TR- PV1 by dietary capsaicin improves endothelium-dependent vasore- laxation and prevents hypertension显示文摘 | Dachun Yang Zhidan Luo Shuangtao Ma | 2010 | Cell Metab2010，12，2： | 1 |
| 6 | Rapid visual detection of Vibrio parahaemolyticus by combining LAMP-CRISPR/Cas12b with heat-labile uracil-DNA glycosylase to eliminate carry-over contamination显示文摘Vibrio parahaemolyticus is a major pathogen frequently found in seafood.Rapid and accurate detection of this pathogen is important for the control of bacterial foodborne diseases and to ensure food safety.In this study,we established a one-pot system that combines uracil-DNA glycosylase(UDG),loopmediated isothermal amplification(LAMP),and clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated protein 12b(Cas12b)for detecting V.parahaemolyticus in seafood.This detection system can effectively perform identification using a single tube and avoid the risk of carryover contamination. | Fang WU Chen LU Wenhao HU Xin GUO Jiayue CHEN Zhidan LUO | 2023 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2023，24，8： | 1 |
| 7 | A STAY‐GREEN protein S l SGR 1 regulates lycopene and β‐carotene accumulation by interacting directly with S l PSY 1 during ripening processes in tomato显示文摘 | Zhidan Luo Junhong Zhang Jinhua Li Changxian Yang Taotao Wang Bo Ouyang Hanxia Li James Giovannoni Zhibiao Ye | 2013 | New Phytol2013，，2： | 1 |
| 8 | Activation of TRP-V1by dietary capsacin improves endothelium-dependent vasorelaxa-tion and prevents hypertension显示文摘 | Dachun Yang Zhidan Luo Shuangtao Ma | 2010 | Cell Metabolism2010，12，： | 1 |
| 9 | Variability in the climate-radial growth correlation of Pinus massoniana of different diameter classes显示文摘The physiological characteristics of trees change with age,suggesting that growth-related climate signals vary over time.This study aimed to clarify the impacts of different diameter classes on the chronological characteristics of Pinus massoniana Lamb.and its response to climatic factors.Chronologies of P inus massoniana were established in small diameter(14.1 cm),middle diameter(27.3 cm),and large diameter(34.6 cm)trees according to dendrochronology.The results show that:(1)radial growth of different diameter classes had varied characteristics and climate sensitivities;(2)radial growth of small diameter trees was affected by climatic factors of the previous and the current year,while large diameter trees were mainly affected by climatic factors of the current year;and(3)precipitation and temperature were key factors that restricted the radial growth of small and large diameter trees,respectively. | Jingjing Qiao Yujun Sun Lei Pan Mi Luo Zhidan Ding Zhao Sun | 2022 | Journal of Forestry Research2022，33，6： | 1 |
| 10 | Activation of TRPV1 by dietary capsaicin improves endothelium-dependent vasorelaxation and prevents hypertension显示文摘 | YANG Dachun LUO Zhidan MA Shuangtao | 2010 | Cell Metabolism2010，12，2： | 1 |
| 11 | Chemical composition of the continental crust as revealed by studies in East China显示文摘 | Gao Shan Luo Tingchuan Zhang Benren Zhang Hongfei Han Yinwen Zhao Zhidan Hu Yiken | 1998 | Geochim Cosmochem Acta1998，62，11： | 1 |
| 12 | Feldspar Lead Isotopic Composition of Granitoids from the Eastern Qinling Orogenic Belt and Their Tectonic Significance显示文摘This paper reports 48 feldspar lead isotope analyses from 27 granitic intrusions,which formed from the Late Proterozic to Mesozoic within the Eastern Qinling oregenic belt. Itis found that the granitic rocks of South Qinling are characterized by a strong block-effect anddepletion in U-Pb and Th-Pb, showing that these rocks came from the same lead isotopetectono-geochemical province, while those of North Qinling are characterized by higher U-Pband Th-Pb for Late Proterozoic to Early Paleozoic ones and lower U-Pb and Th-Pb forLate-Palaeozoic and younger ones in their feldspar lead isotopic composition. In the NorthQinling block, lead isotopic signatures reflect that the source of granitic magma had changedsince the Late Palaeozoic. Comparison of feldspar lead isotopic composition between SouthQinling and North Qinling shows that there is marked difference in lead isotopic compositionfor pre-Palaeozoic granitoids, indicating that the South Qinling and the North Qinling blocksbelong to different tectonic units, but the similarities in lead isotopic composition are quiteclear, which indicates that the South Qinling block had been welded with the North Qinlingblock and that the magma sources of both blocks were identical. The analysis provides directevidence for underplating of the continental crust of South Qinling beneath the North Qinlingblock in the continent-continent interaction stage of the Eastern Qinling oregenic belt. | Zhang Hongfei Zhang Benren Zhao Zhidan Luo Tingchuan and Chen Yuelong Department of Geochemistry, China University of Geosciences, Wuhan, Hubei | 1997 | Acta Geologica Sinica(English Edition)1997，71，2： | 0 |
| 13 | Maize-soybean relay cropping increases soybean yield synergistically by extending the post-anthesis leaf stay-green period and accelerating grain filling显示文摘Relay cropping of Poaceae and Fabaceae promotes high yield and land-use efficiency by allowing a double harvest.However,it is difficult to increase yield synergistically because of the reduced photosynthetic abilities of legume leaves under the shade of graminoids.Leaf photosynthetic capacity in relay cropping systems is associated with ecological niche differentiation and photosynthetic compensation after restoration of normal light.We conducted a field experiment in southwest China in 2020–2021 to evaluate the effects of three cropping patterns:maize–soybean relay cropping(IMS),monoculture maize(MM),and monoculture soybean(SS),and N application levels:no N application(NN:0 kg N ha^(−1)),reduced N(RN:180 kg N ha^(−1)),and conventional N(CN:240 kg N ha^(−1)).Compared to monocropping,relay cropping increased the stay-green traits of maize and soybean by 13%and 89%,respectively.Relay cropping prolonged the leaf stay-green duration in the maize and soybean lag phase by almost 4 and 8 days,respectively.Relay cropping maize(IM)increased the leaf area index(LAI)by 79.4%to 88.5%under NN and 55.5%to 148%under RN.Relay cropping soybean(IS)increased the LAI from 115%to 437%at days 40 to 50 after anthesis.IM increased yield by 65.6%.IS increased yield by 9.7%.HI and system yield were at their highest values under RN.In the relay cropping system,reduced N application extended green leaf duration,increased photosynthesis inside the canopy at multiple levels,ultimately increases soybean yield synergistically. | Yiling Li Ping Chen Zhidan Fu Kai Luo Ping Lin Chao Gao Shanshan Liu Tian Pu Taiwen Yong Wenyu Yang | 2023 | The Crop Journal2023，11，6： | 0 |
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