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| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 2 | Effectiveness of Different Waist Circumference Cut-off Values in Predicting Metabolic Syndrome Prevalence and Risk Factors in Adults in China显示文摘Objective To study the effectiveness of waist circumference cut-off values in predicting the prevalence of metabolic syndrome(MetS) and risk factors in adults in China. Methods A cross-sectional survey was condcuted in 14 provinces(autonomous region, municipality) in China. A total of 47 325 adults aged ≥20 years were selected by multistage stratified sampling, and questionnaire survey and physical and clinical examination were conducted among them. MetS was defined according to the International Diabetes Federation(IDF) criteria and modified IDF criteria.Results The age-standardized prevalence of MetS was 24.2%(22.1% in men and 25.8% in women) and 19.5%(22.1% in men and 18.0% in women) according to the IDF criteria and modified IDF criteria respectively. The age-standardized prevalence of pre-MetS was 8.1%(8.6% in men and 7.8% in women) according to the modified IDF criteria. The prevalence of MetS was higher in urban residents than rural residents and in northern China residents than in southern China residents. The prevalence of central obesity was about 30% in both men and women according to the ethnicity-specific cut-off values of waist circumference for central obesity(90 cm for men and 85 cm for women). Multivariate regression analysis revealed no significant difference in risk factors between the two MetS definitions. Conclusion Using both the modified IDF criteria and ethnicity-specific cut-off values of waist circumference can provide more useful information about the prevalence of MetS in China. | ZHOU Hai Cheng LAI Ya Xin SHAN Zhong Yan JIA Wei Ping YANG Wen Ying LU Ju Ming WENG Jian Ping JI Li Nong LIU Jie TIAN Hao Ming JI Qiu He ZHU Da Long CHEN Li GUO Xiao Hui ZHAO Zhi Gang Li Qiang ZHOU Zhi Guang GE Jia Pu SHAN Guang Liang | 2014 | Biomedical and Environmental Sciences2014，27，5： | 17 |
| 3 | Recent area and ice volume change of Kangwure Glacier in the middle of Himalayas显示文摘This paper calculated and evaluated the area and ice volume changes of Kangwure Glacier in Mt.Xixiabangma,middle of Himalayas in the past 3 decades,based on the field survey of glacier boundary position by differential GPS and glacier depth by Ground Penetrating Radar(GPR),together with the topographic map and remote sense data.The studied data showed that the Kangwure Glacier has experienced significant mass deficit since the 1970s,with 34.2%of area loss,48.2%ofice volume loss and 7.5 m of average thickness decrease.This result revealed that the ice volume loss of Himalayan glaciers was more serious than expected.Analysis of meteorological data from two weather stations in the region of Mt.Xixiabangma,shows that the air temperature of this region has risen from the middle of the 20th century to the beginning of the 21st century.Significant retreat of Himalayas glacier driven by climatic warming will have a remarkable impact on hydrology and ecosystem. | MA LingLong TIAN LiDe PU JianChen WANG PengLing | 2010 | Chinese Science Bulletin2010，55，20： | 17 |
| 4 | Biological coupling anti-wear properties of three typical molluscan shells—Scapharca subcrenata, Rapana venosa and Acanthochiton rubrolineatus显示文摘Molluscan shells are fascinating examples of highly ordered hierarchical structure and complex organic-inorganic biocomposite material. However, their anti-wear properties were rarely studied especially in the perspective of biological coupling. So in the current study three typical shells, Scapharca subcrenata, Rapana venosa and Acanthochiton rubrolineatus, were selected as coupling models to further study their anti-wear properties. Stereomicroscope and scanning electron microscopic observations showed that all these three shells had specific surface morphologies and complicated section microstructures. Importantly, a special structure, pore canal tubules, was discovered in the shells of Scapharca subcrenata and Acanthochiton rubrolineatus, which probably contributed most to their anti-wear properties. X-ray diffraction and micro-Vikers hardness tester were further adopted to analyze the phase compositions and micro-hardness of the shells. The measured results demonstrated that aragonite was the most extensive phase present in the shell, and possesed a relatively high micro-hardness. In this paper, the shells were described in details in morphology, structure and material with emphasis on the relationship with anti-wear property. The study revealed that the selected seashells possess distinct anti-wear properties by complicated mechanisms involving the integrated functions of multiple biological coupling elements, and this would provide inspiration to the design of new bionic wear resistance components. | XiMei Tian ZhiWu Han XiuJuan Li ZhaoGuo Pu LuQuan Ren | 2010 | Science China(Technological Sciences)2010，53，11： | 10 |
| 5 | Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals显示文摘尽管 myocyte 房间移植研究为心肌的梗塞建议了一个有希望的治疗学的潜力,到为心肌的修理的临床的治疗的发展的一个主要障碍是与为移植获得相对同类的室的 myocytes 联系的困难。人的胚胎的干细胞(hESCs ) 是 cardiomyocytes 的有希望的来源。这里,我们报导发信号的 retinoid 在 hESCs 的心脏的区别期间调整 atrial 对室的 myocytes 的命运说明。我们发现少量和 pan-retinoic 酸受体对手 BMS-189453 (RAi ) 显著地增加了 hESCs 的心脏的区别效率。为了调查 retinoid,工作,我们把对待 Noggin+RAi 的文化与对待 Noggin+RA 的文化作比较。我们的结果证明室特定的基因 IRX-4 的表示层次极端地在对待 Noggin+RAi 的文化被提高。MLC-2V,另一个室特定的标记,在对待 Noggin+RAi 的文化,然而并非在对待 Noggin+RA 的文化的 cardiomyocytes 在 cardiomyocytes 的多数被表示。流动 cytometry 分析和 electrophysiological 研究与 64.7 | Qiangzhe Zhang Junjie Jiang Pengcheng Han Qi Yuan Jing Zhang Xiaoqian Zhang Yanyan Xu Henghua Cao Qingzhang Meng Li Chen Tian Tian Xin Wang Pu Li Jurgen Hescheler Guangju Ji Yue Ma | 2011 | Cell Research2011，21，4： | 10 |
| 6 | Dural enhancement detected by magnetic resonance imaging reflecting the underlying causes of cerebral venous sinus thrombosis显示文摘 | TIAN Cheng-lin PU Chuan-qiang | 2012 | Chinese Medical Journal2012，，8： | 8 |
| 7 | Association of Overlapped and Un-overlapped Comorbidities with COVID-19 Severity and Treatment Outcomes: A Retrospective Cohort Study from Nine Provinces in China显示文摘Objective Several COVID-19 patients have overlapping comorbidities. The independent role of each component contributing to the risk of COVID-19 is unknown, and how some non-cardiometabolic comorbidities affect the risk of COVID-19 remains unclear.Methods A retrospective follow-up design was adopted. A total of 1,160 laboratory-confirmed patients were enrolled from nine provinces in China. Data on comorbidities were obtained from the patients’ medical records. Multivariable logistic regression models were used to estimate the odds ratio(OR) and 95% confidence interval(95% CI) of the associations between comorbidities(cardiometabolic or non-cardiometabolic diseases), clinical severity, and treatment outcomes of COVID-19.Results Overall, 158(13.6%) patients were diagnosed with severe illness and 32(2.7%) had unfavorable outcomes. Hypertension(2.87, 1.30–6.32), type 2 diabetes(T2 DM)(3.57, 2.32–5.49),cardiovascular disease(CVD)(3.78, 1.81–7.89), fatty liver disease(7.53, 1.96–28.96), hyperlipidemia(2.15, 1.26–3.67), other lung diseases(6.00, 3.01–11.96), and electrolyte imbalance(10.40, 3.00–26.10)were independently linked to increased odds of being severely ill. T2 DM(6.07, 2.89–12.75), CVD(8.47,6.03–11.89), and electrolyte imbalance(19.44, 11.47–32.96) were also strong predictors of unfavorable outcomes. Women with comorbidities were more likely to have severe disease on admission(5.46,3.25–9.19), while men with comorbidities were more likely to have unfavorable treatment outcomes(6.58, 1.46–29.64) within two weeks.Conclusion Besides hypertension, diabetes, and CVD, fatty liver disease, hyperlipidemia, other lung diseases, and electrolyte imbalance were independent risk factors for COVID-19 severity and poor treatment outcome. Women with comorbidities were more likely to have severe disease, while men with comorbidities were more likely to have unfavorable treatment outcomes. | MA Yan ZHU Dong Shan CHEN Ren Bo SHI Nan Nan LIU Si Hong FAN Yi Pin WU Gui Hui YANG Pu Ye BAI Jiang Feng CHEN Hong CHEN Li Ying FENG Qiao GUO Tuan Mao HOU Yong HU Gui Fen HU Xiao Mei HU Yun Hong HUANG Jin HUANG Qiu Hua HUANG Shao Zhen JI Liang JIN Hai Hao LEI Xiao LI Chun Yan LI Min Qing LI Qun Tang LI Xian Yong LIU Hong De LIU Jin Ping LIU Zhang MA Yu Ting MAO Ya MO Liu Fen NA Hui WANG Jing Wei SONG Fang Li SUN Sheng WANG Dong Ting WANG Ming Xuan WANG Xiao Yan WANG Yin Zhen WANG Yu Dong WU Wei WU Lan Ping XIAO Yan Hua XIE Hai Jun XU Hong Ming XU Shou Fang XUE Rui Xia YANG Chun YANG Kai Jun YUAN Sheng Li ZHANG Gong Qi ZHANG Jin Bo ZHANG Lin Song ZHAO Shu Sen ZHAO Wan Ying ZHENG Kai ZHOU Ying Chun ZHU Jun Teng ZHU Tian Qing ZHANG Hua Min WANG Yan Ping WANG Yong Yan 无 | 2020 | Biomedical and Environmental Sciences2020，33，12： | 8 |
| 8 | Construction of ecological security patterns and ecological restoration zones in the city of Ningbo,China显示文摘Studying an ecological restoration zoning process under the background of ecological security patterns is of great significance to the rapid adjustment and optimization of a landscape pattern.In this study,a remote sensing ecological index and a morphological spatial pattern analysis method were used to assess the quality of habitats and identify ecological sources in the city of Ningbo;ecological corridors,ecological pinch points,and ecological barrier points were extracted by using a circuit theory to construct ecological security patterns and ecological restoration zones.The results indicate:(1)There were 47 ecological sources,and 83 key ecological corridors in Ningbo,and the ecological land area was about 1898.39 km^(2),accounting for 19.89%of the total study area.(2)The ecological source areas were distributed in“one patch and three belts”,and the low-resistance ecological corridors were concentrated in southern Yuyao city,western Haishu district,and central and western Fenghua district;the ecological network in the western and southern regions was dense.(3)There were four types of ecological restoration zones that need to be established,which were prioritized restoration zones,prioritized protection zones,key conservation zones,and general conservation zones distributed hierarchically from inner part towards outside.(4)Ninghai county,Yuyao city,and Fenghua district had large ecological land areas,however,prioritized restoration and protection zones in Ninghai and Fenghua were also large.The analysis results are expected to provide a reference for optimizing a territorial ecological space in a city. | ZHANG Haitao LI Jialin TIAN Peng PU Ruiliang CAO Luodan | 2022 | Journal of Geographical Sciences2022，32，4： | 7 |
| 9 | A new type of ice formation zone found in the Himalayas显示文摘Ice formation was studied on the Dasuopu Glacier located in the Mount Xixabangma (28°23’ N, 85°43’E) in the Himalayas. Snow pits and shallow ice cores are analyzed to reveal ice formation process. The results show that the ice formation process, or in other words, the process of densitification, on the col (7 000 m a.s.l. ) of the Dasuopu Glacier is a stable, slow and gradual process. The snow-ice transformation on the glacier is estimated to be 30—40 m below the surface. The temperature on the Dasuopu Glacier is very low (~ - 14℃ at 10 m) and similar to that in polar type ice cap. We,therefore, speculate that the process of snow-ice transformation is undertaken under snow pressure,and that there is a percolation zone on the Dasuopu Glacier. The high altitude of the col and monsoon snow fall accompnied by heavy cloud and high albedo favorite the percolation zone formation. | Tandong Yao Jianchen Pu Ninlian Wang Lide Tian | 1999 | Chinese Science Bulletin1999，44，5： | 7 |
| 10 | Influencing factors of the neurodevelopment of high-risk infants显示文摘Background High-risk infants refer to newborns exposed to high-risk factors in the prenatal, natal or postnatal period. High-risk infants are at high risk of developmental retardation, and early identification of developmental abnormalities plays a vital role in improving high-risk infants' quality of life.Aims To describe the neurodevelopment of high-risk infants aged less than 1 year old, and to analyse the incidences and influencing factors of neurodevelopmental abnormalities in order to provide a basis for neurodevelopment monitoring and management of highrisk infants.Methods High-risk infants born between January 2016 and December 2016 in the maternity and infant health hospitals of three districts in Shanghai were followed up.The Gesell Developmental Scale was used to assess the neurodevelopmental level at the time of recruitment(0-2 months) and at 9 months. Univariate and multivariate analyses of the influencing factors were conducted.Results 484 high-risk infants(male 51 %, female 49%)with an average gestation age of 36.5±2.2 weeks were recruited. At the time of recruitment, the average age was2.1(0.8) months, and the developmental quotient(DQ)scores of full-term high-risk infants in motor(t=3.542,p=0.001), cognitive(t=3.125, p=0.002), language(t=3.189, p=0.002) and social(t=3.316, p=0.001) areas were higher than those of preterm infants. The incidences of developmental abnormalities of full-term high-risk infants in motor(χ~2 =9.452, p=0.002), cognitive(χ~2=6.258, p=0.012), language(χ~2 =12.319, p =0.001) and social(χ~2 =6.811, p=0.009) areas were lower than the preterm infants. At 9 months, there was no difference in the DQ scores and incidences of developmental abnormalities in four areas between full-term and preterm high-risk infants, and the incidence of developmental abnormalities was around 10%.Conclusion The incidence of neurodevelopmental abnormalities in high-risk infants aged less than 1 year old is high. Preterm birth and parental bad habits are significant factors affecting the neurodevelopment.Monitoring and early interventions help to improve highrisk infants' neurodevelopment. | Yuan Tian Chuncao Zhang Guangjun Yu Xiangying Hu Zheng Pu Liyu Ma | 2018 | General Psychiatry2018，31，6： | 6 |
| 11 | Fibroblasts in an endocardial fibroelastosis disease model mainly originate from mesenchymal derivatives of epicardium显示文摘 | Hui Zhang Xiuzhen Huang Kuo Liu Juan Tang Lingjuan He Wenjuan pu Qiaozhen Liu Yan Li Xueying Tian Yue Wang Libo Zhang Ying Yu Hongyan Wang Ronggui Hu Fengchao Wang Ting Chen Qing-Dong Wang Zengyong Qiao Li Zhang Kathy O Lui Bin Zhou | 2017 | Cell Research2017，27，9： | 6 |
| 12 | A CLASS OF MODIFIED BROYDEN ALGORITHMS显示文摘In this paper we discuss the convergence of the modified Broyden algorithms.We prove that the algorithms are globally convergent for the colltinuous differen tiable function and the rate of convergence of the algorithms is one-step superlinear and n-step second-order for the uniformly convex objective function. From the dis-cussion of this paper, we may get some convergence properties of the Broyden | PU, DG TIAN, WW | 1994 | Journal of Computational Mathematics1994，12，4： | 6 |
| 13 | Genome-wide identification and analysis of AP2/ERF transcription factors related to camptothecin biosynthesis in Camptotheca acuminata显示文摘Camptotheca acuminata produces camptothecin(CPT),a monoterpene indole alkaloid(MIA)that is widely used in the treatment of lung,colorectal,cervical,and ovarian cancers.Its biosynthesis pathway has attracted significant attention,but the regulation of CPT biosynthesis by the APETALA2/ethylene-responsive factor(AP2/ERF)transcription factors(TFs)remains unclear.In this study,a systematic analysis of the AP2/ERF TFs family in C.acuminata was performed,including phylogeny,gene structure,conserved motifs,and gene expression profiles in different tissues and organs(immature bark,cotyledons,young flower,immature fruit,mature fruit,mature leaf,roots,upper stem,and lower stem)of C.acuminata.A total of 198 AP2/ERF genes were identified and divided into five relatively conserved subfamilies,including AP2(26 genes),DREB(61 genes),ERF(92 genes),RAV(18 genes),and Soloist(one gene).The combination of gene expression patterns in different C.acuminata tissues and organs,the phylogenetic tree,the co-expression analysis with biosynthetic genes,and the analysis of promoter sequences of key enzymes genes involved in CPT biosynthesis pathways revealed that eight AP2/ERF TFs in C.acuminata might be involved in CPT synthesis regulation,which exhibit relatively high expression levels in the upper stem or immature bark.Among these,four genes(Cac AP2/ERF123,Cac AP2/ERF125,Cac AP2/ERF126,and Cac AP2/ERF127)belong to the ERF–B2 subgroup;two genes(Cac AP2/ERF149 and Cac AP2/ERF152)belong to the ERF–B3 subgroup;and two more genes(Cac AP2/ERF095 and Cac AP2/ERF096)belong to the DREB–A6 subgroup.These results provide a foundation for future functional characterization of the AP2/ERF genes to enhance the biosynthesis of CPT compounds of C.acuminata. | HU Ya-Ting XU Zhi-Chao TIAN Ya GAO Ran-Ran JI Ai-Jia PU Xiang-Dong WANG Yu LIU Xia SONG Jing-Yuan | 2020 | Chinese Journal of Natural Medicines2020，18，8： | 5 |
| 14 | Environmental information recorded in shallow ice core of Dasuopu glacier in the Qinghai-Tibetan Plateau显示文摘 | Cuilan Huang Tandong Yao Jianchen Pu Keqin Duan Ninglian Wang Lide Tian | 1998 | Chinese Science Bulletin1998，43，22： | 5 |
| 15 | Structural motion of water-resisting key strata lying on overburden显示文摘Water-preserved mining is one of the important parts of the ‘Green Mining’ technological system. The purpose of wa-ter-preserved mining is to prevent water from bursting out in coal mines and thus to protect water resources. The principle of wa-ter-resisting key strata (WKS) is proposed to establish a model capable of guiding and developing water-preserved mining technol-ogy. The experimental model of the WKS is constructed following requirements of the Data Image Correlative Method (DICM). Five experimental schemes are designed according to different combined patterns of the WKS. The water-resisting performance of the WKS is analyzed from observation of structural stability. All of them provide referential value for water-preserved mining. | PU Hai MIAO Xie-xing YAO Bang-hua TIAN Mu-jun | 2008 | Journal of China University of Mining and Technology2008，18，3： | 4 |
| 16 | Essential sequence of the N-terminal cytoplasmic localization-related domain of huntingtin and its effect on huntingtin aggregates显示文摘Huntington's disease(HD) is caused by abnormal CAG repeat expansion in the 5′-end of the Huntingtin(HTT) gene.In addition to the canonical C-terminal full-length huntingtin(htt) nuclear export signal,a cytoplasmic localization-related domain(CLRD) in the N-terminus of htt has recently been reported.Here,we analyzed this domain by introducing deletion and substitution mutations in a truncated N-terminal htt protein and subsequently monitored htt expression,aggregation and subcellular localization by immunocytochemistry and Western blot analysis.We demonstrated that Htt4-17 was the essential sequence for htt cytoplasmic localization.We also found that the subcellular distribution of htt was altered when Htt1-17 was mutated to contain amino acids of different charges,suggesting a structural requirement of Htt1-17 for the cytoplasmic localization of htt. Deletion of the first three amino acids did not affect its association with mitochondria.We observed that defective cytoplasmic localization resulted in a reduction of total htt aggregates and increased nuclear aggregates,indicating that the subcellular distribution of the protein might influence the aggregation process.These studies provide new insight into the molecular mechanism of htt aggregation in HD. | YAN YaPing PENG DanTao TIAN Jun CHI JingWei TAN JieQiong YIN XinZhen PU JiaLi XIA Kun ZHANG BaoRong | 2011 | Science China(Life Sciences)2011，54，4： | 4 |
| 17 | High performance and stability of double perovskite-type oxide NdBa0.5Ca0.5Co1.5Fe0.5O5+δas an oxygen electrode for reversible solid oxide electrochemical cell显示文摘In this study,we successfully synthesized double perovskite-type oxide NdBa0.5Ca0.5Co1.5Fe0.5O5+δ(NBCCF)using a conventional wet chemical method as the oxygen electrode for reversible solid oxide electrochemical cells(RSOCs).The polarization resistance(Rp)of the composite electrode NBCCFGd0.1Ce0.9O2(GDC)is only 0.079Ωcm^2 at 800℃under air.The single cell based on NBCCF-GDC electrode displays a peak power density of 0.941 W/cm^2 in fuel cell mode and a low Rp value of 0.134Ωcm^2.In electrolysis cell mode,the cell displays an outstanding oxygen evolution reaction(OER)activity and shows current density as high as 0.92 A/cm^2 with 50 vol%AH(Absolute Humidity)at 800℃and applied voltage of 1.3 V.Most importantly,the cell exhibits admirable durability of 60 h both in electrolysis mode and fuel cell mode with distinguished reversibility.All these results suggest that NBCCF is a promising candidate electrode for RSOC. | Yunfeng Tian Yun Liu Wenjie Wang Lichao Jia Jian Pu Bo Chi Jian Li | 2020 | Journal of Energy Chemistry2020，29，4： | 4 |
| 18 | Two novel nortriterpenes from the roots of Phlomis umbrosa显示文摘有不平常的骨骼结构的二新奇 28-noroleanane-derived spirocyclic triterpenoids, phlomisone (1 ) , phlomistetraol A (2 ) ,从 Phlomis umbrosa 的根被孤立。他们的结构被分光镜的方法阐明,包括 1D, 2D 原子磁性的回声(NMR ) ,高分辨率的集体 spectrometry (HRMS ) 。 | Pu Liu Li Ying Li Rui Qi Niu Wei Ping Yin Tian Zeng Zhao | 2008 | Chinese Chemical Letters2008，19，10： | 4 |
| 19 | Heritabilities and genetic and phenotypic correlations of litter uniformity and litter size in Large White sows显示文摘Litter uniformity,which is usually represented by within-iitter weight coefficient of variation at birth(CVB),could influence litter performance of sows and the profitability of pig enterprises.The objective of this study was to characterize CVB and its effect on other reproductive traits in Large White sows.Genetic parameters and genetic correlation of the reproductive traits,including CVB,within-iitter weight coefficient of variation at three weeks(CVT),total number born(TNB),number born alive(NBA),number born dead(NBD),gestation length(GL),piglet mortality at birth(M_0),piglet mortality at three weeks(M_3),total litter weight at birth(TLW_0),and total litter weight at three weeks(TLW_3)were estimated for 2 032 Large White litters.The effects of parity and classified litter size on CVB,CVT,TNB,NBA,NBD,GL,M_0,M_3,TLW_0,and TLW_3 were also estimated.The heritabilities of these reproductive traits ranged from 0.06 to 0.17,with the lowest heritabiiity for CVB and the highest heritabiiity for TLW_0.Phenotypic and genetic correlations between these reproductive traits were low to highly positive and negative(ranging from-0.03 to 0.93,and-0.53 to 0.93,respectively).The genetic correlations between TNB and CVB,and between M_0 and CVB were 0.32 and 0.29,respectively.In addition,CVB was significantly influenced by parity and litter size class(P<0.05).All the results suggest that piglet uniformity should be maintained in pig production practices and pig breeding programs. | ZHANG Tian WANG Li-gang SHI Hui-bi YAN Hua ZHANG Long-chao LIU Xin PU Lei LIANG Jing ZHANG Yue-bo ZHAO Ke-bin WANG Li-xian | 2016 | Journal of Integrative Agriculture2016，15，4： | 4 |
| 20 | SMOC:a smart model for open chromatin region prediction in rice genomes显示文摘In eukaryotic genomes, the fundamental unit of chromatin is the nucleosome, which is composed of a histone octamer that contains two copies of each histone, H3, H2A, H2B, and H4 (Bell et al., 2011).Chromatin is wrapped in the nucleus in a highly helical state to play an essential role in gene regulation (Li et al., 2007). | Weijun Guo Hanqing Liu Yifan Wang Pingxian Zhang Dongwei Li Tuoyu Liu Qian Zhang Liwen Yang Li Pu Jian Tian Xiaofeng Gu | 2022 | Journal of Genetics and Genomics2022，49，5： | 3 |
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