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| 1 | Eleven COVID-19 Outbreaks with Local Transmissions Caused by the Imported SARS-CoV-2 Delta VOC-China,July-August,2021显示文摘Starting from December 2019,Wuhan,China,encountered the first outbreak of coronavirus disease 2019(COVID-19)(1-2).The epidemic was successfully suppressed by strict containment so that the number of infected people was reduced to 0 on April 8,2020(3–4).After that,China experienced roughly 3 dozen outbreaks with local transmission caused by imported severe acute respiratory syndrome coronavirus 2(SARS-CoV-2). | Lei Zhou Kai Nie Hongting Zhao Xiang Zhao Bixiong Ye Ji Wang Cao Chen Hong Wang Jiangli Di Jinsong Li Chao Li Zhixiao Chen Ruiqi Ren Peihua Niu Hui Chen Tao Chen Yali Wang Lili Li Bingxue Han Ruhan A Si Chen Dan Li Dan Li Chunxia Jin Xin Zhang Jiangmei Liu Chunyu Xu Yecheng Yao Yenan Feng Zhili Li Bike Zhang Yang Song Peter Hao Yanping Zhang Hao Li Qun Li George F.Gao Guoqing Shi Wenbo Xu | 2021 | China CDC weekly2021，3，41： | 13 |
| 2 | Reproductive management through integration of PGD and MPS-based noninvasive prenatal screening/diagnosis for a family with GJB2-associated hearing impairment显示文摘A couple with a proband child of GJB2(encoding the gap junction protein connexin 26)-associated hearing impairment and a previous pregnancy miscarriage sought for a reproductive solution to bear a healthy child. Our study aimed to develop a customized preconception-to-neonate care trajectory to fulfill this clinical demand by integrating preimplantation genetic diagnosis(PGD), noninvasive prenatal testing(NIPT), and noninvasive prenatal diagnosis(NIPD) into the strategy. Auditory and genetic diagnosis of the proband child was carried out to identify the disease causative mutations. The couple then received in-vitro-fertilization treatment, and eight embryos were obtained for day 5 biopsy. PGD was performed by short-tandem-repeat linkage analysis and Sanger sequencing of GJB2 gene. Transfer of a GJB2 c.235del C heterozygous embryo resulted in a singleton pregnancy. At the 13 th week of gestation, genomic DNA(g DNA) from the trio family and cell-free DNA(cf DNA) from maternal plasma were obtained for assessment of fetal chromosomal aneuploidy and GJB2 mutations. NIPT and NIPD showed the absence of chromosomal aneuploidy and GJB2-associated disease in the fetus, which was later confirmed by invasive procedures and postnatal genetic/auditory diagnosis. This strategy successfully prevented the transmission of hearing impairment in the newborn, thus providing a valuable experience in reproductive management of similar cases and potentially other monogenic disorders. | XIONG WenPing WANG DaYong GAO Yuan GAO Ya WANG HongYang GUAN Jing LAN Lan YAN JunHao ZONG Liang YUAN Yuan DONG Wei HUANG SeXin WU KeLiang WANG YaoShen WANG ZhiLi PENG HongMei LU YanPing XIE LinYi ZHAO Cui WANG Li ZHANG QiuJing GAO Yun LI Na YANG Ju YIN ZiFang HAN Bing WANG Wei CHEN Zi-Jiang WANG QiuJu | 2015 | Science China(Life Sciences)2015，58，9： | 12 |
| 3 | Hf isotopes of zircon megacrysts from the Cenozoic basalts in eastern China显示文摘Cenozoic basalts are widely distributed in east- ern China, and some of them contain zircon megacrysts which are considered to be constituent mineral of the sub- continental lithospheric mantle (SCLM) and petrogenetically related to mantle metasomatism induced by addition of crustal materials. Using the Laser Ablation Multiple Collec- tor Inductively Coupled Plasma Mass Spectrometry (LA-MC-ICPMS), zircon megacrysts from the Cenozoic ba- salts at Changle in Shandong, Mingxi in Fujian, and Penglai in Hainan provinces have been used for Hf isotopic analyses. The data indicate that there is no significant deviation for the different zircon grains in each locale, except those from Penglai. The obtained 176Hf /177Hf ratios are 0.28302 — 0.28308 for Changle, 0.28297—0.28300 for Mingxi, and 0.28288—0.28293 for Penglai, with corresponding εHf values of 8.7—10.8, 7.0—7.9, and 3.9—5.7, respectively. These data display that there existed some regional heterogeneity, but the Hf model ages clustere in the Phanerozoic. Therefore, it is inferred that metasomatism of the lithospheric mantle be- neath eastern China took place in the Phanerozoic, most probably in the Mesozoic-Cenozoic. However, the formation time of the lithospheric mantle is not clearly constrained based on the present Hf isotopic data. | QIU Zhili WU Fuyuan YU Qingyuan XIE Liewen YANG Shufeng | 2005 | Chinese Science Bulletin2005，50，22： | 11 |
| 4 | Numerical and experimental study of magnetic fluid seal with large sealing gap and multiple magnetic sources显示文摘To improve the pressure capability of magnetic fluid seal with more than a 0.25 mm single edge gap,a magnetic fluid sealing structure with multiple magnetic sources which has five permanent magnets was designed.Magnetic field distributions under the pole pieces of the magnetic fluid seal with single and multiple magnetic sources were simulated by finite element method and its sealing pressure difference could be calculated according to the theoretical formula of the magnetic fluid seal.The effects of sealing gap height and magnetic source amount on the sealing capability were investigated experimentally.The theoretical and experimental results were compared,analyzed and discussed.The results demonstrated that the magnetic fluid seal with multiple magnetic sources was an effective method to improve the sealing capability for the rotary shaft with large gaps.The theoretical results agreed well with the experimental results when the height of the single edge gap was equal to 0.4 mm.However,it was found that when the height of the single edge gap was larger than 0.4 mm,the difference between the theoretical values and experimental values increased with the gap height because part of magnetic source had less or even no effect on magnetic fluid sealing capability. | YANG XiaoLong ZHANG ZhiLi LI DeCai | 2013 | Science China(Technological Sciences)2013，56，11： | 10 |
| 5 | Age and genesis of the Myanmar jadeite:Constraints from U-Pb ages and Hf isotopes of zircon inclusions显示文摘Myanmar jadeite (jadeitite) is well known for its economical value and distinctive tectonic locality within the collisional belt between India and Eurasian plates. However, it is less studied for its genesis and geodynamic implications due to precipitous topography, adverse weather and local military conflicts in the area. By means of combined ICP-MS and LA-MC-ICPMS techniques, we have carried out in-situ trace elements, U-Pb and Lu-Hf isotopes for zircon inclusions in a piece of jadeite gem sample. CL imaging suggests that the zircons are metasomatic in origin, and contain mineral inclusions of jadeite and omphacite. Seventy-five analyses on 16 grains of the zircons yield a U-Pb age of 158 ± 2 Ma. The Myanmar zircons differ from other types in that they have no significant Eu anomalies despite high HREE concentrations. Measured 176Hf/177Hf ratios range from 0.282976 to 0.283122, with an average value of 0.283066 ± 7; εHf(t) value of 13.8 ± 0.3 (n=75). These results indicate that the Myanmar jadeite was formed in the Late Jurassic, probably by interaction of fluid released from subducted oceanic slab with mantle wedge. Therefore, its formation has no genetic relationship to the continental collision between Indian and Euroasian plates. | QIU ZhiLi WU FuYuan YANG ShuFeng ZHU Min SUN JinFeng YANG Ping | 2009 | Chinese Science Bulletin2009，54，4： | 9 |
| 6 | Homologous recombination in human embryonic stem cells using CRISPR/Cas9 nickase and a long DNA donor template显示文摘 | Zhili Rong Shengyun Zhu Yang Xu Xuemei Fu | 2014 | Protein & Cell2014，5，4： | 9 |
| 7 | Host metabolism dysregulation and cell tropism identification in human airway and alveolar organoids upon SARS-CoV-2 infection显示文摘The coronavirus disease 2019(COVID-19)pandemic is caused by infection with the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),which is spread primary via respiratory droplets and infects the lungs.Currently widely used cell lines and animals are unable to accurately mimic human physiological conditions because of the abnormal status of cell lines(transformed or cancer cells)and species differences between animals and humans.Organoids are stem cell-derived selforganized three-dimensional culture in vitro and model the physiological conditions of natural organs.Here we showed that SARS-CoV-2 infected and extensively replicated in human embryonic stem cells(hESCs)-derived lung organoids,including airway and alveolar organoids which covered the complete infection and spread route for SARS-CoV-2 within lungs.The infected ceils were ciliated,club,and alveolar type 2(AT2)cells,which were sequentially located from the proximal to the distal airway and terminal alveoli,respectively.Additionally,RNA-seq revealed early cell response to virus infection including an unexpected downregulation of the metabolic processes,especially lipid metabolism,in addition to the well-known upregulation of immune response.Further,Remdesivir and a human neutralizing antibody potently inhibited SARS-CoV-2 replication in lung organoids.Therefore,human lung organoids can serve as a pathophysiological model to investigate the underlying mechanism of SARS-CoV-2 infection and to discover and test therapeutic drugs for COVID-19. | Rongjuan Pei Jianqi Feng Yecheng Zhang Hao Sun Lian Li Xuejie Yang Jiangping He Shuqi Xiao Jin Xiong Ying Lin Kun Wen Hongwei Zhou Jiekai Chen Zhili Rong Xinwen Chen | 2021 | Protein & Cell2021，12，9： | 7 |
| 8 | Highly Efficient and Stable Hydrogen Production in All pH Range by Two-Dimensional Structured Metal-Doped Tungsten Semicarbides显示文摘Transition-metal-doped tungsten semicarbide nanosheets(M-doped W_(2)C NSs,M=Fe,Co,and Ni)have been synthesized through carburization of the mixture of tungsten trioxide,polyvinylpyrrolidone,and metal dopant.Te nanosheets grow directly on the W mesh and have the lateral dimension of several hundreds of nm to a few�m with a thickness of few tens nm.It is demonstrated that the M-doped W_(2)C NSs exhibit superior electrocatalytic activity for hydrogen evolution reaction(HER).Impressively,the Nidoped W_(2)C NSs(2 at%Ni)with the optimized HER activity show extremely low onset overpotentials of 4,9,and 19 mV and modest Tafel slopes of 39,51,and 87 mV dec−1 in acidic(pH=0),neutral(pH=7.2),and basic(pH=14)solutions,respectively,which is close to the commercial Pt/C catalyst.Density functional theory(DFT)calculations also demonstrate that the Gibbs free energy for H adsorption of Ni-W_(2)C is much closer to the optimal valueG_(H∗)=-0.073 eV as compared to-0.16 eV of W_(2)C.Furthermore,nearly 100%Faradaic efciency and long-term stability are obtained in those environments.Tis realization of highly tolerant metal semicarbide catalyst performing on par with commercial Pt/C in all range of pH ofers a key step towards industrially electrochemical water splitting. | Edison H.Ang Khang N.Dinh Xiaoli Sun Ying Huang Jun Yang Zhili Dong Xiaochen Dong Wei Huang Zhiguo Wang Hua Zhang Qingyu Yan | 2019 | Research2019，，1： | 7 |
| 9 | Oxidation behavior of Mo-Si-B alloys at medium-to-high temperatures显示文摘Continuous exploration of high-temperature structural materials is being driven by the needs of gasturbine engines capable of withstanding the high-temperature environment.Relatively low melting points of currently applied superalloys restrain the further improvement of service tempe ratures.With higher melting tempe ratures above 2000℃,Mo-Si-B alloys are regarded as a new generation of ultrahightemperature structural materials.However,oxidation is a concern for the industrial application of Mo-Si-B alloys.Therefore,an in-depth understanding of the oxidation mechanisms may contribute to solving this issue,whereas relevant reviews about their recent advances are lacking.In the current work,a comprehensively systematic review about the oxidation behaviors of Mo-Si-B alloys is described for this purpose. | Kunming Pan Yanping Yang Shizhong Wei Honghui Wu Zhili Dong Yuan Wu Shuize Wang Laiqi Zhang Junping Lin Xinping Mao | 2021 | Journal of Materials Science & Technology2021，，1： | 5 |
| 10 | Synergistic optimization of thermoelectric performance in p-type Ag2Te through Cu substitution显示文摘Superionic conductors,which exhibit liquid-like phonon transport but crystal-like carrier transport,have attracted great attention and broad research interest in the thermoelectric community.Ag_(2)Te is a superionic conductor;however,its small band gap and large Ag vacancy formation energy impede its application as a prominent p-type thermoelectric material.In this work,synergistic optimization of the thermoelectric performance of Ag_(2)Te through Cu substitution is realized through a combination of experimental and theoretical efforts.For the electrical transport,Cu substitution systematically increases the band gap of Ag_(2)Te and reduces the cation vacancy formation energy.These two beneficial effects simultaneously increase the electrical conductivity and suppress the bipolar effect,thereby greatly enhancing the p-type electrical transport properties of Ag_(2)Te.For the thermal transport,alloying Cu_(2)Te with Ag_(2)Te significantly reduces the thermal conductivity through not only point defect scattering but also softening of the interatomic interactions.The latter is attributed to the relatively small Cu atoms vibrating in the oversized 8c sites.This two-fold optimization results in maximum thermoelectric figure of merit zT values of over 1.3 at 773 K for both Ag_(1.2)Cu_(0.8)Te and AgCuTe,demonstrating the great potential of Ag_(2-x)Cu_(x)Te as a promising p-type thermoelectric material system. | Ruonan Wu Zhili Li Yongbo Li Li You Pengfei Luo Jiong Yang Jun Luo | 2019 | Journal of Materiomics2019，5，3： | 4 |
| 11 | Metabolic and Phylogenetic Profile of Bacterial Community in Guishan Coastal Water(Pearl River Estuary), South China Sea显示文摘Characteristics of a microbial community are important as they indicate the status of aquatic ecosystems. In the present study, the metabolic and phylogenetic profile of the bacterioplankton community in Guishan coastal water(Pearl River Estuary), South China Sea, at 12 sites(S1–S12) were explored by community-level physiological profiling(CLPP) with BIOLOG Eco-plate and denaturing gradient gel electrophoresis(DGGE). Our results showed that the core mariculture area(S6, S7 and S8) and the sites associating with human activity and sewage discharge(S11 and S12) had higher microbial metabolic capability and bacterial community diversity than others(S1–5, S9–10). Especially, the diversity index of S11 and S12 calculated from both CLPP and DGGE data(H >3.2) was higher than that of others as sewage discharge may increase water nitrogen and phosphorus nutrient. The bacterial community structure of S6, S8, S11 and S12 was greatly influenced by total phosphorous, salinity and total nitrogen. Based on DGGE fingerprinting, proteobacteria, especially γ- and α-proteobacteria, were found dominant at all sites. In conclusion, the aquaculture area and wharf had high microbial metabolic capability. The structure and composition of bacterial community were closely related to the level of phosphorus, salinity and nitrogen. | HU Xiaojuan LIU Qing LI Zhuojia HE Zhili GONG Yingxue CAO Yucheng YANG Yufeng | 2014 | Journal of Ocean University of China2014，13，5： | 4 |
| 12 | Steganalysis of Low Embedding Rates LSB Speech Based on Histogram Moments in Frequency Domain显示文摘As wavelet packet transform is able to focus on minute change of signals, this study proposes an analytic approach of low embedding steganograpy based on high order Histogram moments in frequency domain(HMFD), which provides a key solution to the feature selection and extraction of HMFD. The detection results are tested with the LSB matching steganograpy of different embedding rates in speech signals, respectively, it is proved that the detection performance with HMFD applied is greater than that of histogram statistical moments.HMFD by Wavelet packet decomposition(WPD) can effectively detect low embedding rates Least significant bit(LSB) speech steganography, its accuracy can be 60.8%while the embedding rate is only 3%. | YANG Wanxia TANG Shanyu LI Miaoqi CHENG Yongfeng ZHOU Zhili | 2017 | Chinese Journal of Electronics2017，26，6： | 3 |
| 13 | Axial gradient excitation accelerates volumetric imaging of two-photon microscopy显示文摘Two-photon excitation fluorescence microscopy(TPM),owing to its capacity for subcellular resolution,intrinsic optical sectioning,and superior penetration depth in turbid samples,has revolutionized biomedical research.However,its layer-by-layer scanning to form a three-dimensional image inherently limits the volumetric imaging speed and increases phototoxicity significantly.In this study,we develop a gradient excitation technique to accelerate TPM volumetric imaging.The axial positions of the fluorophores can be decoded from the intensity ratio of the paired images obtained by sequentially exciting the specimen with two axially elongated two-photon beams of complementary gradient intensities.We achieved a 0.63μm axial localization precision and demonstrate the flexibility of the gradient TPM on various sparsely labeled samples,including bead phantoms,mouse brain tissues,and live macrophages.Compared with traditional TPM,our technique improves volumetric imaging speed(by at least sixfold),decreases photobleaching(i.e.,less than 2.07±2.89%in 25 min),and minimizes photodamages. | Yufeng Gao Xianyuan Xia Lina Liu Ting Wu Tingai Chen Jia Yu Zhili Xu Liang Wang Fei Yan Zhuo Du Jun Chu Yang Zhan Bo Peng Hui Li Wei Zheng | 2022 | Photonics Research2022，10，3： | 3 |
| 14 | Canonical Huffman code based full-text index显示文摘Full-text indices are data structures that can be used to find any substring of a given string. Many full-text indices require space larger than the original string. In this paper, we introduce the canonical Huffman code to the wavelet tree of a string T[1. . .n]. Compared with Huffman code based wavelet tree, the memory space used to represent the shape of wavelet tree is not needed. In case of large alphabet, this part of memory is not negligible. The operations of wavelet tree are also simpler and more efficient due to the canonical Huffman code. Based on the resulting structure, the multi-key rank and select functions can be performed using at most nH0 + jRj(lglgn + lgn lgjRj)+O(nH0) bits and in O(H0) time for average cases, where H0 is the zeroth order empirical entropy of T. In the end, we present an efficient construction algorithm for this index, which is on-line and linear. | Yi Zhang Zhili Pei Jinhui Yang Yanchun Liang | 2008 | Progress in Natural Science:Materials International2008，18，3： | 2 |
| 15 | Software-Defined Networking显示文摘Software-defined networking(SDN)is a promising technology for next-generation networking and has attracted much attention from academics,network equipment manufacturer,network operators,and service providers.It has found applications in mobile,data center,and enterprise networks.The SDN architecture has | Zhili Sun Jiandong Li Kun Yang | 2014 | ZTE Communications2014，12，2： | 2 |
| 16 | Copper nanowire with enriched high‐index facets for highly selective CO_(2) reduction显示文摘Electroreduction of carbon dioxide into fuels and feedstocks with renewable energy is an attractive route to mitigate carbon emission and solve energy crisis.However,how to improve the selectivity of high‐value multicarbon products is still challenging.Here,we demonstrate that the high‐index crystalline surface of copper could be designed and obtained through a simple square‐wave potential treatment on copper nanowires,which is beneficial to improve the selectivity of multi‐carbon products,especially the reaction route towards ethylene.The Faradaic efficiency of C_(2+)products can reach nearly 60%,and hydrogen can be suppressed to below 20%.Density functional theory(DFT)calculations reveal that(311)high‐index facet can activate CO_(2) effectively and promote adsorption of the*COCOH intermediate on copper for ethylene formation,therefore improves the selectivity of ethylene and inhibits the competing hydrogen evolution reaction.This method can be extended to the design of other catalytic systems and has inspirations for other electrochemical catalytic reactions. | Lu Han Benqiang Tian Xiangxiang Gao Yang Zhong Shengnan Wang Shuchang Song Zhili Wang Ying Zhang Yun Kuang Xiaoming Sun | 2022 | SmartMat2022，3，1： | 2 |
| 17 | Mechanical and Thermal Expansion Properties of SiCp/ZAlSi9Mg Composites Produced by Centrifugal Casting显示文摘Centrifugal casting was applied to produce cylindrical castings using SiCp/Al composite slurry,which contained 20%SiC particles.The castings comprised a particle free zone and a particle rich zone.The amount of SiC particles had a dramatic transformation from the particle rich zone to the particle free zone,and the maximum content of SiC particles in the particle rich zone reached up to 40 vol%.The ultimate tensile strength(UTS) of the as-cast SiCp / Al composites in the particle rich zone was 143 MPa,and the fracture was caused by the desorption of SiC particles from matrix alloy.The coefficient of thermal expansion(CTE) of the SiC_p / Al composites in the range of 20 and 100 ℃ was determined as 16.67×10^(-6) s^(-1),and the experimental CTE was lower than the predicted data based on the Kerner's model.The results show that the decrease in CTE in the case of the composites at high temperature stage can be attributed to the solute concentration of Si in Al and the plastic deformation of the matrix alloy in the composites with void architecture. | 王开 jiang tao huang zhili xue hansong yang dazhuang zhu zizong | 2016 | Journal of Wuhan University of Technology(Materials Science)2016，31，1： | 2 |
| 18 | Analysis of the characteristics of heat and mass transfer of a three-effect tubular solar still and experimental research显示文摘 | Zhili Chen Yang Yao Zihang Zheng | 2013 | Desalination2013，43，5： | 1 |
| 19 | Estimating number of transgene copies in transgenic rapeseed by real-time PCR assay withHMG I/Y as an endogenous reference gene显示文摘 | Haibo Weng Aihu Pan Litao Yang Chengmei Zhang Zhili Liu Dabing Zhang | | 0，2004，： | 1 |
| 20 | Study on the manufacture of rayon fiber from a PF/DMSO solvent system显示文摘 | Yang Zhili Wu Guoning Mei Qianfang | 1987 | Cellul Chem Techn1987，，21： | 1 |
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