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| 1 | Multifunctional lymph-targeted platform based Mn@mSiO2 nanocomposites: Combining PFOB dual-mode imaging and DOX for cancer diagnose treatment on for and显示文摘 | Tian Liu Guangyu Wu Jiejun Cheng Qing Lu Yanjie Yao Zhenjing Liu Dongchen Zhu Juan Zhou Jianrong Xu Jun Zhu Dannong He | 2016 | Nano Research2016，9，2： | 11 |
| 2 | Two-photon-excited near-infrared emissive carbon dotsas multifunctional agents for fluorescence imaging andphotothermal therapy显示文摘C dots (CDs) have shown great potential in bioimaging and phototherapy.However, it is challenging to manipulate their fluorescent properties andtherapeutic efficacy to satisfy the requirements for clinic applications. In thisstudy, we prepared S, Se-codoped CDs via a hydrothermal method anddemonstrated that the doping resulted in excitation wavelength-independentnear-infrared (NIR) emissions of the CDs, with peaks at 731 and 820 nm.Significantly, the CDs exhibited a photothermal conversion efficiency of -58.2%,which is the highest reported value for C nanostructures and is comparable tothat of Au nanostructures. Moreover, the CDs had a large two-photon absorptioncross section (-30,045 GM), which allowed NIR emissions and the photothermalconversion of the CDs through the two-photon excitation (TPE) mechanism. Invitro and in vivo tests suggested that CDs can function as new multi functionalphototheranostic agents for the TPE fluorescence imaging and photothermaltheraov of cancer cells. | Minhuan Lan Shaojing Zhao Zhenyu Zhang Li Yan Liang Guo Guangle Niu Jinfeng Zhang Junfang Zhao Hongyan Zhang Pengfei Wang Guangyu Zhu Chun-Sing Lee Wenjun Zhang | 2017 | Nano Research2017，10，9： | 9 |
| 3 | TRANSLUCENT GREEN, an ERF Family Transcription Factor, Controls Water Balance in Arabidopsis by Activating the Expression of Aquaporin Genes显示文摘水是在几乎所有生活有机体的最丰富的分子。Aquaporins 是玩控制房间的水内容的批评 rolesin 的隧道蛋白质。这里,我们报导 AP2/EREBP 家庭抄写 factorin Arabidopsis thaliana 的鉴定,半透明的格林( TG )其在转基因的植物的 overexpression 给了提高的干旱忍耐并且使 leaves.TG 蛋白质成玻璃在原子核是局部性的,在 vitro 绑 DRE 和 GCC 元素,并且在酵母房间充当 transcriptional 使活跃之物。Microarray 分析揭示了 TG,五基因在之中编码 aquaporins 调整的 330 基因的一个总数。短暂表示试金证明 TG 直接绑在 threeaquaporin 基因的倡导者,例如 AtTIP1; 1, AtTIP2; 3,并且 AtPIP2; 2,直接显示那 TG 调整这些基因的表示。而且, AtTIP1 的 overexpression; 1 在转基因的 Arabidopsis 植物导致了使成玻璃的显型,类似于在 TG overexpression 线观察的那些。进野类型的叶子的水注射概括了 vitrifiedleaf 显型,它被从脉管的捆割掉水供应颠倒。一起拿,我们在通过直接激活 aquaporin genes.Key 词的表达式的 Arabidopsis 的数据 supportthat TG 控制水平衡: | Danling Zhu Zhe Wu Guangyu Cao Jigang Li Jia Wei Tomohiko Tsuge Hongya Gua Takashi Aoyama Li-Jia Qu | 2014 | Molecular Plant2014，7，4： | 8 |
| 4 | A draft sequence of the rice (Oryza sativa ssp. indica) genome显示文摘The sequence of the rice genome holds fundamental information for its biology, including physiology, genetics, development, and evolution, as well as information on many beneficial phenotypes of economic significance. Using a 'whole genome shotgun' approach, we have pro-duced a draft rice genome sequence of Oryza sativa ssp. in-dica, the major crop rice subspecies in China and many other regions of Asia. The draft genome sequence is constructed from over 4.3 million successful sequencing traces with an accumulative total length of 2214.9 Mb. The initial assembly of the non-redundant sequences reached 409.76 Mb in length, based on 3.30 million successful sequencing traces with a total length of 1797.4 Mb from an indica variant cultivar 93-11, giving an estimated coverage of 95.29% of the rice genome with an average base accuracy of higher than 99%. The coverage of the draft sequence, the randomness of the sequence distribution, and the consistency of BIG-ASSEM-BLER, a custom-designed software package | YU Jun, HU Songnian, WANG Jun,LI Songgang WONG Ka-Shu Gane, LIU Bin,DENG Yajun, DAI Li, ZHOU Yan,ZHANG Xiuqing, CAO Mengliang, LIU Jing,SUN Jiandong , TANG Jiabin, CHEN Yanjiong,HUANG Xiaobing, LIN Wei, YE Chen, TONG Wei,CONG Lijuan, GENG Jianing, HAN Yujun, LI Lin,LI Wei, HU Guangqiang, HUANG Xiangang,LI Wenjie, LI Jian, LIU Zhanwei, LI Long,LIU Jianping, Ql Qiuhui, LIU Jinsong, LI Li,WANG Xuegang, LU Hong, WU Tingling,ZHU Miao, Nl Peixiang, HAN Hua, DONG Wei,REN Xiaoyu, FENG Xiaoli, GUI Peng,LI Xianran, WANG Hao, XU Xin, ZHAI Wenxue,XU Zhao, ZHANG Jinsong, HE Sijie,ZHANG Jianguo, XU Jichen, ZHANG Kunlin,ZHENG Xianwu, DONG Jianhai, ZENG Wanyong,TAO Lin, CHEN Xuewei, HE Jun, LIU Daofeng,TIAN Wei, TIAN Chaoguang, XIA Hongai,LI Gang, GAO Hui, LI Ping, CHEN Wei ,WANG Xudong, ZHANG Yong, HU Jianfei,WANG Jing, LIU Song, YANG Jian,ZHANG Guangyu, XIONG Yuqing, LI Zhijie,MAO Long, ZHOU Chengshu, ZHU Zhen,CHEN Runsheng, HAO Bailin,ZHENG Weimou, CHEN Shouyi, QUO Wei,LI Guojie, LIU Siqi, HUANG Guyang,TAO Ming, WANG Jian, ZHU Lihuang,YUAN Longping& YANG HuanmingBeijing Genomics Institute/Center of Genomics & Bioinformatics, Chinese Academy of Sciences, Beijing 101300, China Hangzhou Genomics Institute/Institute of Bioinformatics of Zhejiang University/Key Laboratory of Bioinformatics of Zhejiang Province, Hangzhou 310007, China Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, China National Hybrid Rice R & D Center, Changsha 410125, China Laboratory of Bioinformatics, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China College of Life Sciences, Peking University, Beijing 100871, China Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 1Q0080, China Digital China Ltd., Beijing 100080, China Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100080, China Medical College, Xi’an Jiaotong University, Xi’an 710061, ChinaThese authors contributed equally to this work.Corresponding author.Corresponden | 2001 | Chinese Science Bulletin2001，46，23： | 6 |
| 5 | Enhanced mechanical properties of 6082 aluminum alloy via SiC addition combined with squeeze casting显示文摘In order to improve mechanical properties of 6082 aluminum alloy,the SiC_(p)/Al 6082 composites were prepared by the addition of the micron-sized SiC_(p)articles combined with the squeeze casting.The effects of the SiC_(p)content and squeeze casting on the microstructure and mechanical properties of the 6082 aluminum alloy were investigated by SEM,EDS,TEM,tensile testing and hardness testing analysis methods.Research results exhibited that the SiC_(p)content and squeeze casting had a significant impact on the microstructure and mechanical properties of the 6082 aluminum alloy.The addition of the SiC_(p)refined the grain size of the 6082 aluminum alloy while caused the increase of the porosity with increasing the SiC_(p)content,especially in the permanent mold casting condition.Compared to the permanent mold casting,the squeeze casting obviously reduced pore defects,refined grain size and made the SiC_(p)distribute evenly as well as bond tightly with the Al matrix.The tensile strength,yield strength,elongation,elastic modulus and hardness of the 6082 aluminum alloy obtained with the SiC_(p)and squeeze casting were remarkably improved,and the optimal mechanical properties were obtained with a 2 wt.%SiC_(p),and they increased 10.73%,72.7%,193.9%,23.5%and 25.2%,respectively,compared to those of the6082 aluminum alloy obtained without SiC_(p)and squeeze casting.The fracture surface of the SiC_(p)/Al 6082 composites obtained with the squeeze casting was dense and exhibited a ductile fracture mode. | Wenming Jiang Junwen Zhu Guangyu Li Feng Guan Yang Yu Zitian Fan | 2021 | Journal of Materials Science & Technology2021，，29： | 6 |
| 6 | Quantitative and Functional Phosphoproteomic Analysis Reveals that Ethylene Regulates Water Transport via the C-Terminal Phosphorylation of Aquaporin PIP2;1 in Arabidopsis显示文摘乙烯参予众多的细胞的事件和生物过程的规定,包括水损失,在枯萎的叶和花花瓣期间。多样的乙烯回答可以经由在蛋白质 phosphorylation/dephosphorylation 和 ubiquitin/26S 之间的动态相互影响被调整调停 proteasome 的蛋白质降级和朊酶劈开。探讨乙烯怎么通过叉形得多的发信号的小径改变蛋白质 phosphorylation,我们执行了 15 N 稳定的同位素对待空气、对待乙烯的乙烯感觉迟钝的 Arabidopsis 双 loss-of-function 异种 ein3-1/eil1-1 上的基于标签、微分、量的 phosphoproteomics 学习。识别的 Among535 非冗余的 phosphopeptides,二和四 phosphopeptides 起来 -- 并且由乙烯的 downregulated 分别地。aquaporin PIP2 的调整乙烯的 phosphorylation; 1 断然在叶与水流动率和水损失被相关。在有量的 proteomics 的联合的基因研究, immunoblot 分析,原物胀大/缩小实验,并且长叶表示两个的转基因的植物上的水损失试金野类型并且 S280A/S283A-mutated PIP2 ; 1 在里面 Col-0 和 ein3eil1 乙烯增加浇的基因 backgroundssuggest 在由在 PIP2 的 C 终点提高 S280/S283 phosphorylation 的 Arabidopsis 房间的运输率; 1 。未知 kinase 或磷酸酶活动可以参予 EIN3/EIL1 的细胞的功能的起始的起来规定独立人士。这发现贡献我们理解那通常在植物器官的收获以后的存储期间被观察调整乙烯的叶枯萎。 | Dongjin Qing Zhu Yang Mingzhe Li Wai Shing Wong Guangyu Guo Shichang Liu Hongwei Guo Ning Li | 2016 | Molecular Plant2016，9，1： | 6 |
| 7 | In Vivo Corrosion Resistance of Ca-P Coating on AZ60 Magnesium Alloy显示文摘 | Xing Xiao Haiying Yu Qingsan Zhu Guangyu Li Yang Qu Rui Gu | 2013 | Journal of Bionic Engineering2013，10，2： | 5 |
| 8 | Case study of longwave contribution to dust radiative effects over East Asia显示文摘In order to evaluate the impacts of LW contribution to aerosol radiative effects over East Asia,a dust longwave radiative parameterization scheme is integrated into the online mesoscale dust forecasting model GRAPES_CUACE/dust.A case modeling study shows that about half at surface and one third at TOA of the dust negative shortwave radiative forcing are cancelled by its positive longwave forcing over the dust affected area.In the dust layer,longwave radiation emitting by dust cools the atmosphere,which counteracts about 17%of shortwave heating of atmosphere during daytime and results in cooling of atmosphere simply during nighttime.At the same time,the atmosphere beyond the dust layer is warmed because of absorbing the LW radiation emitted by dust layer.Dust longwave contribution exerts more evident impact on the air temperature in lower atmosphere and surface.The surface air temperature cooling rate resulting from the dust solar radiation is cancelled about 40%by dust longwave warming at daytime.At nighttime,dust longwave contribution warms land and sea surface.The online calculation of dust LW radiation reduces about 15%relative errors of predicted AOD based on the dust model with only SW radiative feedback.This case study result suggests that dust longwave contribution has important impacts on the earth-atmosphere energy process,especially on the surface and in the lower atmosphere and should not be neglected in the study of dust radiation effects. | WANG Hong SHI GuangYu ZHU Jing CHEN Bin CHE HuiZheng ZHAO TianLiang | 2013 | Chinese Science Bulletin2013，58，30： | 4 |
| 9 | Structural insights into Ca^2+-activated long-range allosteric channel gating of RyR1显示文摘Ryanodine 受体(RyRs ) 是有分子的质量的巨大的离子隧道的一个班超过 2.2 大 -- 道尔顿。这些隧道调停钙在许多房间发信号。因为超过 80% RyR 蛋白质被合拢进细胞质的集会,留下的残余形成 transmembrane 领域, RyR 隧道的激活和规定发生通过,这被假设了一迄今为止 uncharacterized 远程的 allosteric 机制。这里,我们报导 Ca 2+-activated 的描述由 cryo 电子的开状态的 RyR1 结构显微镜学。结构有 4.9 Å 的一个全面决定;并且 4.2 Å 的一个决定;为核心区域。与以前坚定的 apo/closed-state 结构比较,我们在 Ca 2+ 激活之上观察了隧道的远程的 allosteric gating。深入的结构的分析阐明了新奇隧道门机制和 RyR1 的新奇离子选择机制。我们的工作不仅提供结构的卓见进隧道 gating 和 RyRs 的规定的分子的机制,而且为 six-transmembrane-helix 阳离子隧道家庭为隧道门和离子选择机制使结构的基础清楚些。 | Risheng Wei Xue Wang Yan Zhang Saptarshi Mukherjee Lei Zhang Qiang Chen Xinrui Huang Shan Jing Congcong Liu Shuang Li Guangyu Wang Yaofang Xu Sujie Zhu Alan J Williams Fei Sun Chang-Cheng Yin | 2016 | Cell Research2016，26，9： | 3 |
| 10 | Microwave diagnostics of magnetic field strengths in solar flaring loops显示文摘We have performed microwave diagnostics of the magnetic field strengths in solar flaring loops based on the theory of gyrosynchrotron emission.From Nobeyama Radioheliograph observations of three flare events at 17 and 34 GHz,we obtained the degree of circular polarization and the spectral index of microwave flux density,which were then used to map the magnetic field strengths in post-flare loops.Our results show that the magnetic field strength typically decreases from ~800 G near the loop footpoints to~100 G at a height of 10-25 Mm.Comparison of our results with magnetic field modeling using a flux rope insertion method is also discussed.Our study demonstrates the potential of microwave imaging observations,even at only two frequencies,in diagnosing the coronal magnetic field of flaring regions. | ZHU Rui TAN BaoLin SU YingNa TIAN Hui XU Yu CHEN XingYao SONG YongLiang TAN GuangYu | 2021 | Science China(Technological Sciences)2021，64，1： | 3 |
| 11 | Solitary beam propagation in periodic layered Kerr media enables high-efficiency pulse compression and mode self-cleaning显示文摘Generating intense ultrashort pulses with high-quality spatial modes is crucial for ultrafast and strong-field science and can be achieved by nonlinear supercontinuum generation(SCG)and pulse compression.In this work,we propose that the generation of quasi-stationary solitons in periodic layered Kerr media can greatly enhance the nonlinear lightmatter interaction and fundamentally improve the performance of SCG and pulse compression in condensed media.With both experimental and theoretical studies,we successfully identify these solitary modes and reveal their unified condition for stability.Space-time coupling is shown to strongly influence the stability of solitons,leading to variations in the spectral,spatial and temporal profiles of femtosecond pulses.Taking advantage of the unique characteristics of these solitary modes,we first demonstrate single-stage SCG and the compression of femtosecond pulses from 170 to 22 fs with an efficiency>85%.The high spatiotemporal quality of the compressed pulses is further confirmed by highharmonic generation.We also provide evidence of efficient mode self-cleaning,which suggests rich spatiotemporal self-organization of the laser beams in a nonlinear resonator This work offers a route towards highly efficient,simple,stable and highly flexible SCG and pulse compression solutions for state-of-the-art ytterbium laser technology. | Sheng Zhang Zongyuan Fu Bingbing Zhu Guangyu Fan Yudong Chen Shunjia Wang Yaxin Liu Andrius Baltuska Cheng Jin Chuanshan Tian Zhensheng Tao | 2021 | Light(Science & Applications)2021，10，4： | 3 |
| 12 | Hyaluronic Acid-Gadolinium Complex Nanospheres as Lymphatic System-Specific Contrast Agent for Magnetic Resonance Imaging显示文摘一个新奇 MRI 对比代理人,玻尿的酸金轧建筑群(HA-Gd-DTPA ) nanospheres,被玻尿的酸金轧建筑群和他们的集会的合成准备。物理化学的性质被描绘,并且在 vitro 并且在 vivo 的淋巴的指向也被评估。有合适、稳定的物理化学的性质的 HA-Gd-DTPA nanospheres 能在淋巴的指向学习的 vivo 被用于的结果表演。而且, HA-Gd-DTPA nanospheres 比 Magnevist 的在兔子有在血容器和淋巴容器之间的显然更高的松驰效率和 MRI 对比。因此,新奇 MRI 对比代理人能被淋巴的系统有选择地收起并且在淋巴的系统把代理人用作一个潜在的 MRI 对比。 | Guangyu Wu Huajuan Zhang Zufeng Zhan Qing Lu Jiejun Cheng Jianrong Xu Jun Zhu | 2015 | Chinese Journal of Chemistry2015，33，10： | 2 |
| 13 | Polyamine oxidase 3 is involved in salt tolerance at the germination stage in rice显示文摘Soil salinity inhibits seed germination and reduces seedling survival rate,resulting in significant yield reductions in crops.Here,we report the identification of a polyamine oxidase,OsPAO3,conferring salt tolerance at the germination stage in rice(Oryza sativa L.),through map-based cloning approach.OsPAO3 is up-regulated under salt stress at the germination stage and highly expressed in various organs.Overexpression of OsPAO3 increases activity of polyamine oxidases,enhancing the polyamine content in seed coleoptiles.Increased polyamine may lead to the enhance of the activity of ROS-scavenging enzymes to eliminate over-accumulated H;O;and to reduce Na;content in seed coleoptiles to maintain ion homeostasis and weaken Na;damage.These changes resulted in stronger salt tolerance at the germination stage in rice.Our findings not only provide a unique gene for breeding new salt-tolerant rice cultivars but also help to elucidate the mechanism of salt tolerance in rice. | Guangyu Liu Wanxia Jiang Lei Tian Yongcai Fu Lubin Tan Zuofeng Zhu Chuanqing Sun Fengxia Liu | 2022 | Journal of Genetics and Genomics2022，49，5： | 2 |
| 14 | Relations between man and nature reflected by the evolution of the Neolithic production tools in the Three Gorges region of Yangtze River,China显示文摘The relations between man and nature reflected by evolution of Neolithic production tools in the Three Gorges region of Yangtze River is discussed in this paper.Our results show that there is a good correlation between the percentage vibration of cutting tool types and the environmental evolution indicated by the natural profile nearby.It is possible for ancestors from the Three Gorges region to learn the advantage of mortise and tenon in the early Neolithic Age because they used the stones as vital tools for processing woods.The hunting method in the early Neolithic is throwing,which was inherited in the mid-Neolithic Age when hunting with arrow and bow was developed.Fishing tools are found at the same period.Numbers of net sinkers and spinning wheels unearthed from the strata of the Western Zhou Dynasty from Zhongba Site reveal the fact of fishing with net,while a mass of fishbone pits indi- cate the powerful productivity brought by new production tools.Quantity of stone spades and stone hoes proves that cultivation agriculture by hoe is extremely attached importance by the ancestors in the Three Gorges region.Moreover,the developed agriculture in Daxi Culture at Zhongbao Island benefits from the landform,climate,traffic location,etc.Otherwise,the reason that the farming tools declined in the late Neolithic Age is related to the extreme flood during the early Xia Dynasty and the fishing hunting preference of some ancient settlements.This research shows that ancestors of the Three Gorges region during the Neolithic Age attached importance to fish hunting and cultivation, fought against the natural environment by production tools,constantly created and improved them, then comprehensively utilized them to evolve the relations between man and nature. | GuangYao Zhu Cheng Zhu GuangYue Shi ZhiBin Sun | 2008 | Chinese Science Bulletin2008，53，S1： | 2 |
| 15 | Interaction of hepatitis B virus with tumor suppressor gene p53: its significance and biological function | ZHU Minghua , GU Guangyu, LI Fangmei, WANG Wenliang and DAI Yimin(Department of Pathology, Chang Hai Hospital, The Second Military Medical University, Shanghai 200433, China) | 2002 | Progress in Natural Science:Materials International2002，12，1： | 1 |
| 16 | QoS-Aware Power Allocation Scheme for Relay Satellite Networks显示文摘This paper investigated a QoS-aware power allocation for relay satellite networks.For the given QoS requirements,we analyzed the signal model of relay transmission and formulated the power minimization problem which is non-convex and difficult to solve.To find the optimal solution to the considered problem,we first analyzed the optimization problem and equivalently turn it into a convex optimization problem.Then,we provided a Lagrangian dual-based method to obtain the closed-form of the power allocation and provided an iterative algorithm to the optimal solution.Moreover,we also extended the results to the cooperative transmission mode.Finally,simulation results were provided to verify the superiority of the proposed algorithm. | Jin’ao Yu Xiaogang Tang Shibing Zhu Haopeng Sun Lunxin Zhong Guangyu Yang | 2021 | Journal of Beijing Institute of Technology2021，30，1： | 1 |
| 17 | Light intensity affects the growth and flavonol biosynthesis of Ginkgo ( Ginkgo biloba L.)显示文摘 | You Xu Guibin Wang Fuliang Cao Cancan Zhu Guangyu Wang Yousry A. El-Kassaby | 2014 | New Forests2014，，6： | 1 |
| 18 | Geochemical characteristics of the Zhaolanzhuang sour gas accumulation and thermochemical sulfate reduction in the Jixian Sag of Bohai Bay Basin显示文摘 | Zhang Shuichang Zhu Guangyu Liang Yingbo | 2005 | Organic Geochemistry2005，36，12： | 1 |
| 19 | Using webeast text :or semantic event detection in broadcast sports video 显示文摘 | Xu Changsheng Zhang Yifan Zhu Guangyu | 2008 | IEEE Trans on Multimedia2008，10，7： | 1 |
| 20 | Human behavior analysis for highlight ranking in broadcast racket sports Video 显示文摘 | Zhu Guangyu Huang Oingming Xu Changsheng | 2007 | IEEE Trans on Multimedia2007，9，6： | 1 |
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