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| 1 | Effects of Short-Term Forest Bathing on Human Health in a Broad-Leaved Evergreen Forest in Zhejiang Province,China显示文摘Objective To investigate the effects of short-term forest bathing on human health.Methods Twenty healthy male university students participated as subjects and were randomly divided into two groups of 10.One group was sent on a two-night trip to a broad-leaved evergreen forest,and the other was sent to a city area.Serum cytokine levels reflecting inflammatory and stress response,indicators reflecting oxidative stress,the distribution of leukocyte subsets,and plasma endothelin-1 (ET-1) concentrations were measured before and after the experiment to evaluate the positive health effects of forest environments.A profile of mood states (POMS) evaluation was used to assess changes in mood states.Results No significant differences in the baseline values of the indicators were observed between the two groups before the experiment.Subjects exposed to the forest environment showed reduced oxidative stress and pro-inflammatory level,as evidenced by decreased malondialdehyde,interleukin-6,and tumor necrosis factor α levels compared with the urban group.Serum cortisol levels were also lower than in the urban group.Notably,the concentration of plasma ET-1 was much lower in subjects exposed to the forest environment.The POMS evaluation showed that after exposure to the forest environment,subjects had lower scores in the negative subscales,and the score for vigor was increased.Conclusion Forest bathing is beneficial to human health,perhaps through preventive effects related to several pathological factors. | MAO Gen Xiang LAN Xiao Guang CAO Yong Bao CHEN Zhuo Mei HE Zhi Huat LV Yuan Dong WANG Ya Zhen HU Xi Lian WANG Guo Fu YAN Jing | 2012 | Biomedical and Environmental Sciences2012，25，3： | 20 |
| 2 | Antioxidant and Anti-inflammatory Capacity of Ferulic Acid Released from Wheat Bran by Solid-state Fermentation of Aspergillus niger显示文摘Objective A strain of Aspergillus niger(A. niger), capable of releasing bound phenolic acids from wheat bran, was isolated. This strain was identified by gene sequence identification. The antioxidant and anti-inflammatory capacity of ferulic acid released from wheat bran by this A. niger strain(FA-WB) were evaluated. Methods Molecular identification techniques based on PCR analysis of specific genomic sequences were conducted; antioxidant ability was examined using oxygen radical absorbance capacity(ORAC), cellular antioxidant activity(CAA) assays, and erythrocyte hemolysis assays. RAW264.7 cells were used as a model to detect anti-inflammatory activity. Results The filamentous fungal isolate was identified to be A. niger. ORAC and CAA assay showed that FA-WB had better antioxidant activity than that of the ferulic acid standard. The erythrocyte hemolysis assay results suggested that FA-WB could attenuate AAPH-induced oxidative stress through inhibition of reactive oxy gen species(ROS) generation. FA-WB could significantly restore the AAPH-induced increase in intracellular antioxidant enzyme activities to normal levels as well as inhibit the intracellular malondialdehyde formation. TNF-?, IL-6, and NO levels indicated that FA-WB can inhibit the inflammation induced by lipopolysaccharide(LPS). Conclusion Ferulic acid released from wheat bran by a new strain of A. niger had good anti-inflammatory activity and better antioxidant ability than standard ferulic acid. | YIN Zhi Na WU Wen Jia SUN Chong Zhen LIU Hui Fan CHEN Wen Bo ZHAN Qi Ping LEI Zhuo Gui XIN Xuan MA Juan Juan YAO Kun MIN Tian ZHANG Meng Meng WU Hui | 2019 | Biomedical and Environmental Sciences2019，32，1： | 14 |
| 3 | Fifty-eight cases of ocular ischemic diseases caused by carotid artery stenosis显示文摘背景到眼睛的血供应来自眼的动脉的网膜的中央脉管的系统和睫的脉管的系统。眼的动脉源自 ipsilateral 内部颈动脉动脉。如果吸藏或狭窄发生在颈动脉动脉,到眼的动脉的血灌注变得不够,导致前面、以后的眼睛的局部缺血的症状。学习是评估眼睛的 ischemic 疾病的临床的特征和风险因素的这的目的由颈动脉动脉 stenosis.Methods 引起了这研究是有颈动脉动脉狭窄的 145 个病人的回顾的评论。有形成的颈动脉动脉狭窄引起的眼睛的 ischemic 疾病的症状的 58 个病人组织 A 和仅仅有的颈动脉动脉狭窄形成了组 B 的另外的 87 个病人。我们分析了疾病,和相对风险因素的原因和功课,由比较在组 A 的颈动脉动脉狭窄的度是的二 groups.Results 比那高在组 B。并且组 A 有眼的动脉流动的更大的减少。男性,高血压, hyperlipidemia,并且吸烟显著地与颈动脉动脉狭窄有关。黑 fugax 是在组 A 的最普通的眼睛的症状。眼睛的 ischemic 疾病主要包括了 ischemic 眼的神经病, central/branch 网膜的动脉吸藏, ophthalmoplegia externa,和眼睛的 ischemic syndrome.Conclusions 颈动脉动脉有眼睛的 ischemic 疾病的狭窄相互关联。眼科医师必须为眼睛的症状观察,它是在一些病人的发作症状。 | LUO Rong-jiang LIU Shao-rui LI Xiao-min ZHUO Ye-hong TIAN Zhen | 2010 | Chinese Medical Journal2010，，19： | 14 |
| 4 | Association Between Diurnal Temperature Range and Respiratory Tract Infections显示文摘Objective This study aimed to assess the association between emergency-room visits for respiratory tract infection (RTI) with diurnal temperature range (DTR), a weather parameter closely associated with urbanization and global climate change. Methods We conducted a semiparametric time-series analysis to estimate the percentage increase in emergency-room visits for RTI associated with changes in DTR after adjustment for daily weather conditions (temperature and relative humidity) and outdoor air pollution. Results DTR was significantly associated with daily emergency-room visits for RTI. An increase of 1 °C in the current-day (L0) and in the 2-day moving average (L01) DTR corresponded to a 0.94% [95% confidence interval (CI), 0.34%-1.55%] and 2.08% (95% CI, 1.24%-2.93%) increase in emergency-room visits for RTI, respectively. Conclusion DTR was associated with increased risk of RTI. More studies are needed to understand the impact of DTR on respiratory health. | GE Wen Zhen XU Feng ZHAO Zhuo Hui ZHAO Jin Zhuo KAN Hai Dong | 2013 | Biomedical and Environmental Sciences2013，26，3： | 10 |
| 5 | Ecotoxicological effect of zinc oxide nanoparticles on soil microorganisms显示文摘最近的年里的锌氧化物 nanoparticles (ZnO-NPs ) 的普遍生产和使用形成了潜在的威胁到生态系统。这研究试图用实验室缩影测试在土壤微生物上调查 ZnO-NPs 的 ecotoxicological 效果。呼吸,加氨,脱氢酶(DH ) 活动,并且荧光灯 diacetate hydrolase (FDAH ) 活动被用作 ecotoxicological 参数。结果在每 g 土壤与 1 mg ZnO-NPs 对待的中立土壤显示出那(新鲜,中立) ,加氨显著地在三的学习时期期间被禁止月,而是抑制率在增加时间上减少了。在呼吸的抑制在测试的第一个月内被观察。在各种各样的 ZnO-NPs 治疗(1 mg, 5 mg,和每 g 土壤的 10 mg ZnO-NPs ) , DH 活动和 FDAH 活动在一个月的学习经期期间被禁止。为两项酶活动,在 ZnO-NPs 和抑制率的集中之间有积极 doseresponse 关系,但是曲线由于 ZnO-NPs 毒性的变化随着时间的过去变化了。土壤类型在土壤影响了 ZnONPs 的毒性。毒性在酸土壤是最高的,由中立土壤列在后面。毒性在碱的土壤是相对低的。毒性没被说明因为由 Zn 2+ 免除了 ZnO-NPs。有生物学的目标的 ZnO-NPs 的直接相互作用可能是原因之一。在中立、酸的土壤的土壤微生物上的 ZnO-NPs 的不利效果值得注意。 | Zhaoyi SHEN Zhuo CHEN Zhen HOU Tingting LI Xiaoxia LU | 2015 | Frontiers of Environmental Science & Engineering2015，9，5： | 5 |
| 6 | Mapping Soil Electrical Conductivity Using Ordinary Kriging Combined with Back-propagation Network显示文摘Accurate mapping of soil salinity and recognition of its influencing factors are essential for sustainable crop production and soil health. Although the influencing factors have been used to improve the mapping accuracy of soil salinity, few studies have considered both aspects of spatial variation caused by the influencing factors and spatial autocorrelations for mapping. The objective of this study was to demonstrate that the ordinary kriging combined with back-propagation network(OK_BP), considering the two aspects of spatial variation, which can benefit the improvement of the mapping accuracy of soil salinity. To test the effectiveness of this approach, 70 sites were sampled at two depths(0–30 and 30–50 cm) in Ningxia Hui Autonomous Region, China. Ordinary kriging(OK), back-propagation network(BP) and regression kriging(RK) were used in comparison analysis; the root mean square error(RMSE), relative improvement(RI) and the decrease in estimation imprecision(DIP) were used to judge the mapping quality. Results showed that OK_BP avoided the both underestimation and overestimation of the higher and lower values of interpolation surfaces. OK_BP revealed more details of the spatial variation responding to influencing factors, and provided more flexibility for incorporating various correlated factors in the mapping. Moreover, OK_BP obtained better results with respect to the reference methods(i.e., OK, BP, and RK) in terms of the lowest RMSE, the highest RI and DIP. Thus, it is concluded that OK_BP is an effective method for mapping soil salinity with a high accuracy. | HUANG Yajie LI Zhen YE Huichun ZHANG Shiwen ZHUO Zhiqing XING An HUANG Yuanfang | 2019 | Chinese Geographical Science2019，29，2： | 5 |
| 7 | Mass production of Co3O4@CeO2 core@shell nanowires for catalytic CO oxidation显示文摘在这研究,公司 3 O 4@CeO2 core@shell nanowires 成功地经由公司的热分解被准备(公司 3)0.5(OH) | Jiangman Zhen Xiao Wang Dapeng Liu Zhuo Wang Junqi Li Fan Wang Yinghui Wang Hongjie Zhang | 2015 | Nano Research2015，8，6： | 4 |
| 8 | Morphology-selective synthesis of active and durable gold catalysts with high catalytic performance in the reduction of 4-nitrophenol显示文摘由 nanosized Au 粒子组成的一系列新奇催化剂与血小板(PL ) 在 micro-mesoporous ZSM-5/SBA-15 (ZSBA ) 材料限制了,杆(RD ) ,并且六角形棱柱(HP ) 形态学在 situ 被综合了。这些催化剂拥有 SBA-15 和 ZSM-5 结构并且在 ZSBA 以内由 Au nanoparticles (NP ) 的监禁展出他们的活跃地点的优秀稳定性。催化剂深入地被描绘了理解他们的结构性质关系。金 NP 尺寸和催化剂的毛孔结构,被发现对锻烧温度和合成条件敏感,被显示在 4-nitrophenol 的减小起重要作用。与短 mesochannels (210 nm ) 和一条大毛孔直径(6.7 nm ) ,而与长 mesochannels 和相对更小的毛孔尺寸, Au/ZSBA-HP 和 Au/ZSBA-RD 给穷人看催化活动, Au/ZSBA-PL 在 4-nitrophenol 的减小展出高催化的性能。在有不同金 NP 尺寸的催化剂的情况中,有 4.0 nm 的一条 Au NP 直径的 Au/ZSBA-PL-350 展出最高的反应率常数(0.14 min -1) 和周转频率(0.0341 s -1) 。另外, 4-nitrophenol 的减小上的反应参数的效果系统地被调查了。为在 Au/ZSBA 催化剂上的 4-nitrophenol 减小的可能的机制被建议。 | Daowei Gao Xin Zhang Xiaoping Dai Yuchen Qin Aijun Duan Yanbing Yu Hongying Zhuo Hairui Zhao Pengfang Zhang Yan Jiang Jianmei Li Zhen Zhao | 2016 | Nano Research2016，9，10： | 4 |
| 9 | Differences in major ions as well as hydrogen and oxygen isotopes of sediment pore water and lake water显示文摘Isotopic and chemical compositions of pore water(PW) are highly relevant to environmental and forensic study. Five lake water(LW)samples and five sediment samples were collected to investigate the effects of pore sizes of sediments on PW chemistry and stable isotopes and determine mechanisms controlling their variations. Six pore water fractions were extracted from different-sized pores in each sediment sample at six sequential centrifugal speeds for chemical and isotopic analysis. The sediments consisted mainly of quartz, feldspar, and clay minerals. The hydrogen and oxygen isotopic compositions of PW are mainly controlled by the overlying LW, although the lag effect of exchange between overlying LW and PW results in isotopic differences when recharge of LW is quicker than isotopic exchange in PW. Identical isotopic compositions of PW from sediments with different pore sizes indicate that isotopic exchange of water molecules with different pore sizes is a quick process. The ratio of average total dissolved solid(TDS) concentration of PW to TDS concentration of LW shows a strong relationship with adsorption capacity of sediments, demonstrating that remobilization of ions bound to sediments mainly causes a chemical shift from LW to PW.Concentrations of Ca^(2+), Mg^(2+),and Cl^-in PW remain unchanged,while concentrations of Na^+,K^+,and SO_4^(2-) slightly increase with decreasing pore size. Chemical differences of PW from sediments with different pore sizes are governed by ion adsorption properties and surface characteristics of different-si zed particles. | Zhuo Zhang Hua-ming Guo Zhen Wang | 2018 | Water Science and Engineering2018，11，2： | 3 |
| 10 | Stress and sleep:a survey based on wearable sleep trackers among medical and nursing staff in Wuhan during the COVID-19 pandemic显示文摘Backgroud COVID-19 pandemic has significantly affected the sleep health of local medical and nursing staff.Aim We used wearable pulse oximeters to monitor and screen the medical and nursing staff working in hospitals designated for COVID-19 in the Wuhan area.This study aimed to establish a reliable basis to provide sleep intervention for the medical and nursing staff.Methods Thirty medical and nursing staff members with symptoms of insomnia were instructed to wear medical ring-shaped pulse oximeters to monitor their sleep overnight.We also used the Insomnia Severity Index(ISI)and the Chinese version of the Self-Reporting Questionnaire(SRQ-20)to evaluate the severity of insomnia and mental health status,respectively,for each participant.Results Among the 30 participants,only 26 completed the screening.Ten cases(38.5%)demonstrated moderate to severe sleep apnoea-hypopnea syndrome(SAHS)when using an oxygen desaturation index^15 times/hour as the cut-off value.Participants with comorbid moderate to severe SAHS had significantly higher ISI and SRQ scores(p values 0.034 and 0.016,respectively)than those in the insomnia group.Correlation analysis revealed that ISI was positively correlated with total sleep time(TST)(r=0.435,p=0.026),and negatively correlated with deep sleep(r=-0.495,p=0.010);furthermore,patient SRQ scores were positively correlated with TST,sleep efficiency(SE)and REM(rapid eyes movement)sleep%(r=0.454 and 0.389,0.512;p=0.020,0.050 and 0.008,respectively).Stepwise logistic regression indicated that SRQ-20 and sex were risk factors for insomnia with comorbid SAHS,and their OR values were 1.516 and 11.56(95%Cl 1.053 to 2.180 and 1.037 to 128.9),respectively.Conclusion Medical and nursing staff with insomnia showed clear signs of comorbid sleep apnoea attributable to stress.The wearable pulse oximeters accurately monitored the participants'breathing when asleep. | Kaiming Zhuo Cunyou Gao Xiaohui Wang Chen Zhang Zhen Wang | 2020 | General Psychiatry2020，33，3： | 3 |
| 11 | Rehabilitation of vision disorder and improved quality of life in patients with primary open angle glaucoma显示文摘背景主要开的角度绿内障( POAG )是 POAG 的病原学提出的不可逆的 blindness.The 变量的一个普通原因为治疗和 rehabilitation.We 的重要挑战在治疗期间分析了一个大 POAG 耐心的队揭示视觉混乱的可能的原因,估计生活( VRQL )的视觉相关的质量,并且我们由常规眼的检查和视觉 f 在 500 个 POAG 病人( 890 只眼睛)分析了梦幻的骚乱评估使复权 treatments.Methods | LUO Rong-jiang LIU Shao-rui TIAN Zhen ZHU Wen-hui ZHUO YE-hong LIAO Rui-duan | 2011 | Chinese Medical Journal2011，，17： | 3 |
| 12 | In situ fabrication of organic electrochemical transistors on a microfluidic chip显示文摘Microfluid chips integrating with organic electrochemical transistors (OECTs) are useful for manufacturing biosensors with high throughput and large-scale analyses. We report here the utilization of alternating current (AC) electrodeposition to fabricate OECTs in situ on a microfiuid chip. With this method, the organic semiconductor (OS) layer with a channel length of 8μm was readily prepared without requiring the postbonding process in the conventional construction of microfluidic chips. Poly(3,4-ethylenedioxythiophene):poly(4-styrenesulfonate)/graphene quantum dots (PEDOT:PSS/GQDs) composites with different morphologies, such as microfilms, nanodendrites and nanowires were electropolymerized. The mass transfer process of the electropolymerization reaction was evidenced to be diffusion limited. Morphologies, growth directions, and chemical structures of OS layers could be tuned by the amplitude and the frequency of the AC voltage. Transfer and output characteristic curves of OECTs were measured on the microfluidic chip. The maximum transconductance, on/off current ratio and threshold voltage measured in the experiment was 1.58 mS, 246, and 0.120 V, respectively. | Jianlong Ji Mangmang Li Zhaowei Chen Hongwang Wang Xiaoning Jiang Kai Zhuo Ying Liu Xing Yang Zhen Gu Shengbo Sang Yang Shu | 2019 | Nano Research2019，12，8： | 3 |
| 13 | Polycystic Ovary Syndrome is not Associated with Offspring Birth Weight: A Mendelian Randomization Study显示文摘Polycystic ovary syndrome(PCOS) is a common metabolic and hormonal disorder afflicting approximately 5%–20% of all women of reproductive age~([1]). PCOS is characterized with hyperandrogenism,oligo-anovulation, and a polycystic ovarian morphology. The syndrome features heterogeneous manifestations, such as hirsutism, menstrual dysfunction, and obesity. Women with PCOS are at higher risk of developing multiple metabolic comorbidities and subsequent cardiovascular complications even beyond childbearing age. | WU Peng Fei LI Rui Zhuo ZHANG Wan SU Zhong Zhen LIN Yu Hong | 2021 | Biomedical and Environmental Sciences2021，34，2： | 3 |
| 14 | Reevaluation of the Holotype of Odorrana schmackeri Boettger,1892(Amphibia:Anura:Ranidae) and Characterization of One Cryptic Species in O.schmackeri sensu lato through Integrative Approaches显示文摘The Odorrana schmackeri sensu la to is a group of cascade frogs that are widely distributed in southern China.However,their taxonomy has long been unresolved and several cryptic species have been reported in the past decade.Previous analyses revealed the existence of three sympatrie species(i.c,O.schmackeri,O.hejiangensis and O.sp2) at the type locality of O.schmackeri(Gaojiayan Town,Yichang City,Hubei Province,China).However,the lack of an original description for the holotype specimen(SMF6241) of O.schmackeri poses a confusing and controversial problem in species nomination within this group.Here,we reevaluate the taxonomic affinities of SMF6241 and examine the distinctness of O.sp2 based on specimens from the type locality.We use integrative approaches that combine morphology with 10 microsatellite loci and bioacoustics.Canonical discriminant analysis of morphological characteristics revealed three distinct groupings(i.e.,O.schmackeri,O.hejiangensis and O.sp2) and attributed SMF6241 to O.schmackeri.Genetic clustering analysis of nuclear DNA also identified three corresponding clusters.In addition,analysis of interspecific variation in morphometrics and acoustics showed divergence between O.sp2 and its sympatric congeners.All lines of evidence from morphological,molecular and bioacoustic approaches suggest the species status of O.sp2,namely Odorrana ichangensis Chen,sp.nov.Overall,this study resolves the taxonomic assignment of the holotype of O.schmackeri and provides an example for species delimitation using integrative approaches. | Huijun SHEN Yanjun ZHU Zhen LI Zhuo CHEN Xiaohong CHEN | 2020 | Asian Herpetological Research2020，11，4： | 3 |
| 15 | High-performance fiber-integrated multifunctional graphene-optoelectronic device with photoelectric detection and optic-phase modulation显示文摘In graphene-based optoelectronic devices,the ultraweak interaction between a light and monolayer graphene leads to low optical absorption and low responsivity for the photodetectors and relative high half-wave voltage for the phase modulator.Here,an integration of the monolayer graphene onto the side-polished optical fiber is demonstrated,which is capable of providing a cost-effective strategy to enhance the light–graphene interaction,allowing us to obtain a highly efficient optical absorption in graphene and achieve multifunctions:photodetection and optical phase modulation.As a photodetector,the device has ultrahigh responsivity(1.5×10^(7) A/W)and high external quantum efficiency(>1.2×10^(9)%).Additionally,the polybutadiene/polymethyl methacrylate(PMMA)film on the graphene can render the device an optical phase modulator through the large thermo-optic effect of the PMMA.As a phase modulator,the device has a relatively low half-wave voltage of 3 V with a 16 dB extinction ratio in Mach–Zehnder interferometer configuration. | LINQING ZHUO PENGPENG FAN SHUANG ZHANG YUANSONG ZHAN YANMEI LINYU ZHANG DONGQUAN LI ZHEN CHE WENGUO ZHU HUADAN ZHENG JIEYUAN TANG JUN ZHANG YONGCHUN ZHONG WENXIAO FANG GUOGUANG LU JIANHUI YU ZHE CHEN | 2020 | Photonics Research2020，8，12： | 3 |
| 16 | Application research of enhanced in-situ micro-ecological remediation of petroleum contaminated soil显示文摘Experimental study of enhanced in-situ micro-ecological remediation of petroleum contaminated loess soil was carried out in Zhongyuan oil production areas, and the enhanced in-situ micro-ecological remediation technique includes optimistic in-situ microbial communities, physical chemistry methods, alfalfa planting and regulation of soil environmental elements. Experiments showed that the oil content in the contaminated soil with oil content about 2 898.25 mg/kg can be reduced about 98.61% after in-situ micro-ecological remediation for 99 days, which demonstrated the effectiveness of in-situ micro-ecological remediation methods for petroleum contaminated soil in central plains of China, and explored the practical and feasible application of these methods. | ZHANG Sheng ZHANG Cui-yun HE Ze CHEN Li ZHANG Fa-wang YIN Mi-ying NING Zhuo SUN Zhen-hua ZHEN Shi-jun | 2016 | Journal of Groundwater Science and Engineering2016，4，3： | 2 |
| 17 | Influence of environmental factors on arsenic accumulation and biotransformation using the aquatic plant species Hydrilla verticillata显示文摘Hydrilla verticillata(waterthyme)has been successfully used for phytoremediation in arsenic(As)contaminated water.To evaluate the effects of environmental factors on phytoremediation,this study conducted a series of orthogonal design experiments to determine optimal conditions,including phosphorus(P),nitrogen(N),and arsenate(As(Ⅴ))concentrations and initial pH levels,for As accumulation and biotransformation using this aquatic plant species,while also analyzing As species transformation in culture media after 96-hr exposure.Analysis of variance and the signal-to-noise ratio were used to identify both the effects of these environmental factors and their optimal conditions for this purpose.Results indicated that both N and P significantly impacted accumulation,and N was essential in As species transformation.High N and intermediate P levels were critical to As accumulation and biotransformation by H.verticillata,while high N and low P levels were beneficial to As species transformation in culture media.The highest total arsenic accumulation was(197.2±17.4)μg/g dry weight when As(V)was at level 3(375μg/L),N at level 2(4 mg/L),P at level 1(0.02 mg/L),and pH at level 2(7).Although H.verticillata is highly efficient in removing As(Ⅴ)from aquatic environments,its use could be potentially harmful to both humans and the natural environment due to its release of highly toxic arsenite.For cost-effective and ecofriendly phytoremediation of As-contaminated water,both N and P are helpful in regulating As accumulation and transformation in plants. | Yuan Zhao Zhuo Zhen Zhenhong Wang Liqing Zeng Changzhou Yan | 2020 | Journal of Environmental Sciences2020，32，4： | 2 |
| 18 | Uncertainty quantification and reduction in metal additive manufacturing显示文摘Uncertainty quantification(UQ)in metal additive manufacturing(AM)has attracted tremendous interest in order to dramatically improve product reliability.Model-based UQ,which relies on the validity of a computational model,has been widely explored as a potential substitute for the time-consuming and expensive UQ solely based on experiments.However,its adoption in the practical AM process requires overcoming two main challenges:(1)the inaccurate knowledge of uncertainty sources and(2)the intrinsic uncertainty associated with the computational model.Here,we propose a data-driven framework to tackle these two challenges by combining high throughput physical/surrogate model simulations and the AM-Bench experimental data from the National Institute of Standards and Technology(NIST).We first construct a surrogate model,based on high throughput physical simulations,for predicting the three-dimensional(3D)melt pool geometry and its uncertainty with respect to AM parameters and uncertainty sources.We then employ a sequential Bayesian calibration method to perform experimental parameter calibration and model correction to significantly improve the validity of the 3D melt pool surrogate model.The application of the calibrated melt pool model to UQ of the porosity level,an important quality factor,of AM parts,demonstrates its potential use in AM quality control.The proposed UQ framework can be generally applicable to different AM processes,representing a significant advance toward physicsbased quality control of AM products. | Zhuo Wang Chen Jiang Pengwei Liu Wenhua Yang Ying Zhao Mark F.Horstemeyer Long-Qing Chen Zhen Hu Lei Chen | 2020 | npj Computational Materials2020，，1： | 2 |
| 19 | Comparison of acute pneumonia caused by SARS-CoV-2 and other respiratory viruses in children:a retrospective multi-center cohort study during COVID-19 outbreak显示文摘Background:Until January 18,2021,coronavirus disease-2019(COVID-19)has infected more than 93 million individuals and has caused a certain degree of panic.Viral pneumonia caused by common viruses such as respiratory syncytial virus,rhinovirus,human metapneumovirus,human bocavirus,and parainfluenza viruses have been more common in children.However,the incidence of COVID-19 in children was significantly lower than that in adults.The purpose of this study was to describe the clinical manifestations,treatment and outcomes of COVID-19 in children compared with those of other sources of viral pneumonia diagnosed during the COVID-19 outbreak.Methods:Children with COVID-19 and viral pneumonia admitted to 20 hospitals were enrolled in this retrospective multi-center cohort study.A total of 64 children with COVID-19 were defined as the COVID-19 cohort,of which 40 children who developed pneumonia were defined as the COVID-19 pneumonia cohort.Another 284 children with pneumonia caused by other viruses were defined as the viral pneumonia cohort.The epidemiologic,clinical,and laboratory findings were compared by Kolmogorov-Smirnov test,t-test,Mann-Whitney U test and Contingency table method.Drug usage,immunotherapy,blood transfusion,and need for oxygen support were collected as the treatment indexes.Mortality,intensive care needs and symptomatic duration were collected as the outcome indicators.Results:Compared with the viral pneumonia cohort,children in the COVID-19 cohort were mostly exposed to family members confirmed to have COVID-19(53/64 vs.23/284),were of older median age(6.3 years vs.3.2 years),and had a higher proportion of ground-glass opacity(GGO)on computed tomography(18/40 vs.0/38,P<0.001).Children in the COVID-19 pneumonia cohort had a lower proportion of severe cases(1/40 vs.38/284,P=0.048),and lower cases with high fever(3/40 vs.167/284,P<0.001),requiring intensive care(1/40 vs.32/284,P<0.047)and with shorter symptomatic duration(median 5d vs.8d,P<0.001).The proportion of cases with evaluated inflammatory indicators,biochemical indicators related to organ or tissue damage,D-dimer and secondary bacterial infection were lower in the COVID-19 pneumonia cohort than those in the viral pneumonia cohort(P<0.05).No statistical differences were found in the duration of positive PCR results from pharyngeal swabs in 25 children with COVID-19 who received antiviral drugs(lopinavir-ritonavir,ribavirin,and arbidol)as compared with duration in 39 children without antiviral therapy(median 10d vs.9d,P=0.885).Conclusions:The symptoms and severity of COVID-19 pneumonia in children were no more severe than those in children with other viral pneumonia.Lopinavir-ritonavir,ribavirin and arbidol do not shorten the duration of positive PCR results from pharyngeal swabs in children with COVID-19.During the COVID-19 outbreak,attention also must be given to children with infection by other pathogens infection. | Guang-Li Ren Xian-Feng Wang Jun Xu Jun Li Qiong Meng Guo-Qiang Xie Bo Huang Wei-Chun Zhu Jing Lin Cheng-He Tang Sheng Ye Zhuo Li Jie Zhu Zhen Tang Ming-Xin Ma Cong Xie Ying-Wen Wu Chen-Xi Liu Fang Yang Yu-Zong Zhou Ying Zheng Shu-Ling Lan Jian-Feng Chen Feng Ye Yu He BenQing Wu Long Chen Si-Mao Fu Cheng-Zhong Zheng Yuan Shi | 2021 | Military Medical Research2021，8，4： | 2 |
| 20 | Heck reaction catalyzed by Pd supported on LDH - F hydrotalcite 显示文摘 | Zhou Hao Zhuo Guang Lan Jiang Xuan Zhen | 2006 | Journal of Molecular Catalysis A : Chemical2006，248，： | 1 |
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