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| 1 | Vertical distribution of aerosol optical properties based on aircraft measurements over the Loess Plateau in China显示文摘Vertical distributions of aerosol optical properties based on aircraft measurements over the Loess Plateau were measured for the first time during a summertime aircraft campaign, 2013 in Shanxi, China. Data from four flights were analyzed. The vertical distributions of aerosol optical properties including aerosol scattering coefficients(σsc), absorption coefficients(σab),Angstr?m exponent(α), single scattering albedo(ω), backscattering ratio(βsc), aerosol mass scattering proficiency(Q sc) and aerosol surface scattering proficiency(Q sc′) were obtained. The mean statistical values of σsc were 77.45 Mm-1(at 450 nm), 50.72 Mm-1(at 550 nm), and32.02 Mm-1(at 700 nm). The mean value of σab was 7.62 Mm-1(at 550 nm). The mean values ofα, βsc and ω were 1.93, 0.15, and 0.91, respectively. Aerosol concentration decreased with altitude. Most effective diameters(ED) of aerosols were less than 0.8 μm. The vertical profiles of σsc,, α, βsc, Q sc and Q sc′ showed that the aerosol scattering properties at lower levels contributed the most to the total aerosol radiative forcing. Both α and βsc had relatively large values, suggesting that most aerosols in the observational region were small particles. The mean values of σsc, α, βsc, Q sc, Q sc′, σab and ω at different height ranges showed that most of the parameters decreased with altitude. The forty-eight hour backward trajectories of air masses during the observation days indicated that the majority of aerosols in the lower level contributed the most to the total aerosol loading, and most of these particles originated from local or regional pollution emissions. | Junxia Li Xingang Liu Liang Yuan Yan Yin Zhanqing Li Peiren Li Gang Ren Lijun Jin Runjun Li Zipeng Dong Yiyu Li Junmei Yang | 2015 | Journal of Environmental Sciences2015，27，8： | 6 |
| 2 | Two regimes of Atlantic multidecadal oscillation: cross-basin dependent or Atlantic-intrinsic显示文摘The Atlantic Multidedal Oscillation(AMO) is a prominent mode of sea surface temperature variability in the Atlantic and incurs significant global influence. Most coupled models failed to reproduce the observed 50–80-year AMO, but were overwhelmed by a 10–30-year AMO. Here we show that the 50–80-year AMO and 10–30-year AMO represent two different AMO regimes. The key differences are:(1) the 50–80-year AMO involves transport of warm and saline Atlantic water into the Greenland-Iceland-Norwegian(GIN)Seas prior to reaching its maximum positive phase, while such a transport is weak for the 10–30-year AMO;(2) the zonality of atmospheric variability associated with the 50–80 year AMO favors the transport of warm and saline water into the GIN Seas;(3) the disappearance of Pacific variability weakens the zonality of atmospheric variability and the transport of warm and saline water into the GIN Seas, leading to the weakening of the 50–80-year AMO. In contrast, the 10–30-year AMO does not show dependence on the variability in Pacific and in the GIN Seas and may be an Atlantic-intrinsic mode. Our results suggest that differentiating these AMO regimes and a better understanding of the cross-basin connections are essential to reconcile the current debate on the nature of AMO and hence to its reliable prediction, which is still lacking in most of coupled models. | Pengfei Lin Zipeng Yu Jianhua Lü Mengrong Ding Aixue Hu Hailong Liu | 2019 | Science Bulletin2019，64，3： | 6 |
| 3 | In situ development of highly concave and compositionconfined PtNi octahedra with high oxygen reduction reaction activity and durability显示文摘有为催化氧减小反应(ORR ) 的唯一的结构的 PtNi 金属 nanocrystals 的控制综合体吸引了大兴趣。这里,我们报导单个水晶的 PtNi octahedra 的一步舞合成与在里面开发 situ 高度为 ORR 是最佳的凹面特征和自我限制的作文。揭示的详细研究充满磅的播种、随后的 Pt/Ni 合作减小,和 PtNi 融合导致了一致单个水晶的 PtNi octahedra,并且 Ni 富有的表面蚀刻的 Ni 方面分离和氧的联合导致了凹度并且限制了 Ni 内容。凹面 PtNi nanocrystals 以两个比商业地可得到的 Pt/C 催化剂展出了高得多的 ORR 性能特定的活动(高 29.1 倍) 并且集体活动(高 12.9 倍) 在 0.9 V (对可逆的氢电极(RHE )) 。没有凹度,表演也比 PtNi octahedra 的高,证实更高的活动是仔细与它的形态学有关。而且,凹面 octahedra 也由于不稳定的地点的钝化在 ORR (在在 0.6 和 1.1 V 对 RHE 之间的 10,000 个周期以后仍然是的 93% 集体活动) 展出了显著稳定性。 | Enbo Zhu Yongjia Li Chin-Yi Chiu Xiaoqing Huang Mufan Li Zipeng Zhao Yuan Liu Xiangfeng Duan Yu Huang | 2016 | Nano Research2016，9，1： | 4 |
| 4 | Integrated traffic-power simulation framework for electric vehicle charging stations based on cellular automaton显示文摘This paper presents a novel integrated framework for simulating the charging load of an electric vehicle charging station. The framework is built based on the cellular automaton model, including five modules: vehicle generation, charging station, lane change, speed update and boundary clear. The proposed framework can effectively stimulate the system dynamics of the traffic system and charging power process in a charging station. Case studies have verified its feasibility and effectiveness. | Yue XIANG Zipeng LIU Jichun LIU Youbo LIU Chenghong GU | 2018 | Journal of Modern Power Systems and Clean Energy2018，6，4： | 4 |
| 5 | Nanoparticle‑Loaded Polarized‑Macrophages for Enhanced Tumor Targeting and Cell‑Chemotherapy显示文摘Cell therapy is a promising strategy for cancer therapy.However,its therapeutic efficiency remains limited due to the complex and immunosuppressive nature of tumor microenvironments.In this study,the“cell-chemotherapy”strategy was presented to enhance antitumor efficacy.M1-type macrophages,which are therapeutic immune cells with both of immunotherapeutic ability and targeting ability,carried sorafenib(SF)-loaded lipid nanoparticles(M1/SLNPs)were developed.M1-type macrophages were used both as therapeutic tool to provide immunotherapy and as delivery vessel to target deliver SF to tumor tissues for chemotherapy simultaneously.M1-type macrophages were obtained by polarizing macrophages using lipopolysaccharide,and M1/SLNPs were obtained by incubating M1-type macrophages with SLNP.Tumor accumulation of M1/SLNP was increased compared with SLNP(p<0.01),which proved M1/SLNP could enhance tumor targeting of SF.An increased ratio of M1-type macrophages to M2-type macrophages,and the CD3^+CD4^+T cells and CD3^+CD8^+T cell quantities in tumor tissues after treatment with M1/SLNP indicated M1/SLNP could relieve the immunosuppressive tumor microenvironments.The tumor volumes in the M1/SLNP group were significantly smaller than those in the SLNP group(p<0.01),indicating M1/SLNP exhibited enhanced antitumor efficacy.Consequently,M1/SLNP showed great potential as a novel cellchemotherapeutic strategy combining both cell therapy and targeting chemotherapy. | Teng Hou Tianqi Wang Weiwei Mu Rui Yang Shuang Liang Zipeng Zhang Shunli Fu Tong Gao Yongjun Liu Na Zhang | 2021 | Nano-Micro Letters2021，13，1： | 1 |
| 6 | Eddy-resolving Simulation of CAS-LICOM3 for Phase 2 of the Ocean Model Intercomparison Project显示文摘A 61-year(1958–2018)global eddy-resolving dataset for phase 2 of the Ocean Model Intercomparison Project has been produced by the version 3 of Chinese Academy of Science,the State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics/Institute of Atmospheric Physics(LASG/IAP)Climate system Ocean Model(CAS-LICOM3).The monthly and a part of the surface daily data in this study can be accessed on the Earth System Grid Federation(ESGF)node.Besides the details of the model and experiments,the evolutions and spatial patterns of large-scale and mesoscale features are also presented.The mesoscale features are reproduced well in the high-resolution simulation,as the mesoscale activities can contribute up to 50%of the total SST variability in eddy-rich regions.Also,the large-scale circulations are remarkably improved compared with the low-resolution simulation,such as the climatological annual mean SST(the RMSE is reduced from 0.59°C to 0.47°C,globally)and the evolution of Atlantic Meridional Overturning Circulation.The preliminary evaluation also indicates that there are systematic biases in the salinity,the separation location of the western boundary currents,and the magnitude of eddy kinetic energy.All these biases are worthy of further investigation. | Yiwen LI Hailong LIU Mengrong DING Pengfei LIN Zipeng YU Yongqiang YU Yao MENG Yunlong LI Xiaodong JIAN Jinrong JIANG Kangjun CHEN Qian YANG Yaqi WANG Bowen ZHAO Jilin WEI Jinfeng MA Weipeng ZHENG and Pengfei WANG | 2020 | Advances in Atmospheric Sciences2020，37，10： | 1 |
| 7 | FGOALS-g3 Model Datasets for CMIP6 Flux-Anomaly-Forced Model Intercomparison Project显示文摘The Flux-Anomaly-Forced Model Intercomparison Project(FAFMIP)is an endorsed Model Intercomparison Project in phase 6 of the Coupled Model Intercomparison Project(CMIP6).The goal of FAFMIP is to investigate the spread in the atmosphere–ocean general circulation model projections of ocean climate change forced by increased CO2,including the uncertainties in the simulations of ocean heat uptake,global mean sea level rise due to ocean thermal expansion and dynamic sea level change due to ocean circulation and density changes.The FAFMIP experiments have already been conducted with the Flexible Global Ocean–Atmosphere–Land System Model,gridpoint version 3.0(FGOALS-g3).The model datasets have been submitted to the Earth System Grid Federation(ESGF)node.Here,the details of the experiments,the output variables and some baseline results are presented.Compared with the preliminary results of other models,the evolutions of global mean variables can be reproduced well by FGOALS-g3.The simulations of spatial patterns are also consistent with those of other models in most regions except the North Atlantic and the Southern Ocean,indicating large uncertainties in the regional sea level projections of these two regions. | Yaqi WANG Zipeng YU Pengfei LIN Hailong LIU Jiangbo JIN Lijuan LI Yanli TANG Li DONG Kangjun CHEN Yiwen LI Qian YANG Mengrong DING Yao MENG Bowen ZHAO Jilin WEI Jinfeng MA and Zhikuo SUN | 2020 | Advances in Atmospheric Sciences2020，37，10： | 1 |
| 8 | The Brassicaceae-specific secreted peptides,STMPs,function in plant growth and pathogen defense显示文摘Low molecular weight secreted peptides have recently been shown to affect multiple aspects of plant growth,development,and defense responses.Here,we performed stepwise BLAST filtering to identify unannotated peptides from the Arabidopsis thaliana protein database and uncovered a novel secreted peptide family,secreted transmembrane peptides(STMPs).These low molecular weight peptides,which consist of an N-terminal signal peptide and a transmembrane domain,were primarily localized to extracellular compartments but were also detected in the endomembrane system of the secretory pathway,including the endoplasmic reticulum and Golgi.Comprehensive bioinformatics analysis identified 10 STMP family members that are specific to the Brassicaceae family.Brassicaceae plants showed dramatically inhibited root growth uponexposure to chemically synthesized STMP1 and STMP2.Arabidopsis overexpressing STMP1,2,4,6,or 10 exhibited severely arrested growth,suggesting that STMPs are involved in regulating plant growth and development.In addition,in vitro bioassays demonstrated that STMP1,STMP2,and STMP10 have antibacterial effects against Pseudomonas syringae pv.tomato DC3000,Ralstonia solanacearum,Bacillus subtilis,and Agrobacterium tumefaciens,demonstrating that STMPs are antimicrobial peptides.These findings suggest that STMP family members play important roles in various developmental events and pathogen defense responses in Brassicaceae plants. | Zipeng Yu Yang Xu Lifei Zhu Lei Zhang Lin Liu Di Zhang Dandan Li Changai Wu Jinguang Huang Guodong Yang Kang Yan Shizhong Zhang Chengchao Zheng | 2020 | Journal of Integrative Plant Biology2020，62，4： | 1 |
| 9 | Amphiphilic small molecular mates match hydrophobic drugs to form nanoassemblies based on drug-mate strategy显示文摘Nanomedicine has made great progress in the targeted therapy of cancer. Here, we established a novel drug-mate strategy by studying the formulation of nanodrugs at the molecular level. In the drug-mate combination, the drug is a hydrophobic drug that is poorly soluble in water, and the mate is an amphiphilic small molecule (SMA) that has both hydrophilic and lipophilic properties. We proposed that the hydrophobic drug could co-assemble with a suitable SMA on a nanoscale without additive agents. The proof-ofconcept methodology and results were presented to support our hypothesis. We selected five hydrophobic drugs and more than ten amphiphilic small molecules to construct a library. Through molecular dynamic simulation and quantum chemistry computation,we speculated that the formation of nanoassemblies was related to the binding energy of the drug-mate, and the drug-mate interaction must overcome drug-drug interaction.Furthermore, the obtained SF/VECOONa nanoassemblieswas selected as a model, which had an ultra-high drug loading content (46%), improved pharmacokinetics, increased bioavailability, and enhanced therapeutic efficacy. In summary, the drug-mate strategy is an essential resource to design exact SMA for many hydrophobic drugs and provides a reference for the design of a carrier-free drug delivery system. | Leiqiang Han Shuang Liang Weiwei Mu Zipeng Zhang Limin Wang Shumin Ouyang Bufan Yao Yongjun Liu Na Zhang | 2022 | Asian Journal of Pharmaceutical Sciences2022，17，1： | 1 |
| 10 | Structure, function, and mechanism of the TNFAIP8 (TIPE) family of proteins in cancer and inflammation显示文摘The multiple roles of the tumor necrosis factor(TNF)-α-inducible protein 8(TNFAIP8),also named TIPE family of proteins have been shown in tumor and inflammation progression and regulation of cellular autophagy and apoptosis.In this review,we found that the TIPE family showed highly homologous sequences and conserved functional domains,such as the death effector domain(DED)-like domain but displayed different roles and mechanisms in different biological activities.For example,while TIPE is primarily associated with tumor progression and antitumor drug resistance,TIPE1 suppresses tumor progression in most instances.TIPE2 has multiple roles in tumor progression regulation,and antitumor drug resistance.Moreover,TIPE2 was also involved in inflammatory response regulation,tumor typing,and staging.A few studies reported that TIPE3 was engaged in tumor development by activating the phosphatidylinositol-3-kinase(PI3K)/protein kinase B(AKT)signaling pathway.The structure,function,and mechanism of the TIPE family in cancer and inflammation have been summarized in this review.This might serve as a reference for further research on the TIPE family and shed new light on the crosstalk among antitumor responses,inflammation,and immunology. | ZIPENG LIN CHUXI TANG LE KANG GUANXI LAI SHIWEN LIU YIXIANG WU HUIQUN TIAN SONG LIU | 2023 | BIOCELL2023，47，10： | 0 |
| 11 | Stress compensation based on interfacial nanostructures for stable perovskite solar cells显示文摘The long-term stability issue of halide perovskite solar cells hinders their commercialization.The residual stress-strain affects device stability,which is derived from the mismatched thermophysical and mechanical properties between adjacent layers.In this work,we introduced the Rb_(2)CO_(3)layer at the interface of SnO_(2)/perovskite with the hierarchy morphology of snowflake-like microislands and dendritic nanostructures.With a suitable thermal expansion coefficient,the Rb_(2)CO_(3)layer benefits the interfacial stress relaxation and results in a compressive stress-strain in the perovskite layer.Moreover,reduced nonradiative recombination losses and optimized band alignment were achieved.An enhancement of open-circuit voltage from 1.087 to 1.153 V in the resultant device was witnessed,which led to power conversion efficiency(PCE)of 22.7%(active area of 0.08313 cm^(2))and 20.6%(1 cm2).Moreover,these devices retained 95%of its initial PCE under the maximum power point tracking(MPPT)after 2700 h.It suggests inorganic materials with high thermal expansion coefficients and specific nanostructures are promising candidates to optimize interfacial mechanics,which improves the operational stability of perovskite cells. | Cheng Zhu Xi Wang Hangxuan Li Chenyue Wang Ziyan Gao Pengxiang Zhang Xiuxiu Niu Nengxu Li Zipeng Xu Zhenhuang Su Yihua Chen Huachao Zai Haipeng Xie Yizhou Zhao Ning Yang Guilin Liu Xueyun Wang Huanping Zhou Jiawang Hong Xingyu Gao Yang Bai Qi Chen | 2023 | Interdisciplinary Materials2023，2，2： | 0 |
| 12 | The Super-large Ensemble Experiments of CAS FGOALS-g3显示文摘A super-large ensemble simulation dataset with 110 members has been produced by the fully coupled model FGOALS-g3 developed by researchers at the Institute of Atmospheric Physics,Chinese Academy of Sciences.This is the first dataset of large ensemble simulations with a climate system model developed by a Chinese modeling center.The simulation has the largest realizations up to now worldwide in terms of single-model initial-condition large ensembles.Each member includes a historical experiment(1850-2014)and an experiment(2015-99)under the very high greenhouse gas emissions Shared Socioeconomic Pathway scenario(SSP5-8.5).The dataset includes monthly and daily temperature,precipitation,and other variables,requiring storage of 275 TB.Additionally,the surface air temperature(SAT)and land precipitation simulated by the FGOALS-g3 super-large ensemble have been validated and projected.The ensemble can capture the response of SAT and land precipitation to external forcings well,and the internal variabilities can be quantified.The availability of more than 100 realizations will help researchers to study rare events and improve the understanding of the impact of internal variability on forced climate changes. | Pengfei LIN Bowen ZHAO Jilin WEI Hailong LIU Wenxia ZHANG Xiaolong CHEN Jie JIANG Mengrong DING Wenmin MAN Jinrong JIANG Xu ZHANG Yuewen DING Wenrong BAI Chenyang JIN Zipeng YU Yiwen LI Weipeng ZHENG Tianjun ZHOU | 2022 | Advances in Atmospheric Sciences2022，39，10： | 0 |
| 13 | Stability of dimensionally stable anode for chlorine evolution reaction显示文摘Chlorine(Cl2)is one of the most important chemicals produced by the electrolysis of brine solutions and is a key raw material for many areas of industrial chemistry.For nearly half a century,dimensionally stable anode(DSA)made from a mixture of RuO_(2) and TiO_(2) solid oxides coated on Ti substrate has been the most widely used electrode for chlorine evolution reaction(CER).In harsh operating environments,the stability of DSAs remains a major challenge greatly affecting their lifetime.The deactivation of DSAs significantly increases the cost of the chlor-alkali industry due to the corrosion of Ru and the formation of the passivation layer TiO_(2).Therefore,it is urgent to develop catalysts with higher activity and stability,which requires a thorough understanding of the deactivation mechanism of DSA catalysts.This paper reviews existing references on the deactivation mechanisms of DSA catalysts,including both experimental and theoretical studies.Studies on how CER selectivity affects electrode stability are also discussed.Furthermore,studies on the effects of the preparation process,elemental composition,and surface/interface structures on the DSA stability and corresponding improvement strategies are summarized.The development of other non-DSA-type catalysts with comparable stability is also reviewed,and future opportunities in this exciting field are also outlined. | Ziliang Deng Shuying Xu Chuhao Liu Xueqiang Zhang Mufan Li Zipeng Zhao | 2024 | Nano Research2024，17，3： | 0 |
| 14 | Surface engineering of 1D nanocatalysts for value-added selective electrooxidation of organic chemicals显示文摘Electrolytic water splitting by renewable energy is a technology with great potential for producing hydrogen(H_(2))without carbon emission,but this technical route is hindered by its huge energy(electricity)cost,which is mainly wasted by the anode oxygen evolution reaction(OER)while the value of the anode product(oxygen)is very limited.Replacing the high-energy-cost OER with a selective organic compound electrooxidation carried out at a relatively lower potential can reduce the electricity cost while producing value-added chemicals.Currently,H_(2) generation coupled with synthesis of value-added organic compounds faces the challenge of low selectivity and slow generation rate of the anodic products.One-dimensional(1D)nanocatalysts with a unique morphology,well-defined active sites,and good electron conductivity have shown excellent performance in many electrocatalytic reactions.The rational design and regulation of 1D nanocatalysts through surface engineering can optimize the adsorption energy of intermediate molecules and improve the selectivity of organic electrooxidation reactions.Herein,we summarized the recent research progress of 1D nanocatalysts applied in different organic electrooxidation reactions and introduced several different fabrication strategies for surface engineering of 1D nanocatalysts.Then,we focused on the relationship between surface engineering and the selectivity of organic electrooxidation reaction products.Finally,future challenges and development prospects of 1D nanocatalysts in the coupled system consisting of organic electrooxidation and hydrogen evolution reactions are briefly outlined. | Yongping Yang Chuhao Liu Tinglu Song Mufan Li Zipeng Zhao | 2024 | Nano Research2024，17，3： | 0 |
| 15 | Function identification of Md TIR1 in apple root growth benefited from the predicted Md PPI network显示文摘Protein–protein interaction(PPI)network analysis is an effective method to identify key proteins during plant development,especially in species for which basic molecular research is lacking,such as apple(Malus domestica).Here,an MdPPI network containing 30806 PPIs was inferred in apple and its quality and reliability were rigorously verified.Subsequently,a rootgrowth subnetwork was extracted to screen for critical proteins in root growth.Because hormone-related proteins occupied the largest proportion of critical proteins,a hormonerelated sub-subnetwork was further extracted from the root-growth subnetwork.Among these proteins,auxin-related M.domestica TRANSPORT INHIBITOR RESISTANT 1(MdTIR1)served as the central,high-degree node,implying that this protein exerts essential roles in root growth.Furthermore,transgenic apple roots overexpressing an MdTIR1 transgene displayed increased primary root elongation.Expression analysis showed that MdTIR1 significantly upregulated auxin-responsive genes in apple roots,indicating that it mediates root growth in an auxin-dependent manner.Further experimental validation revealed that MdTIR1 interacted with and accelerated the degradation of MdIAA28,MdIAA43,andMdIAA46.Thus,MdTIR1-mediated degradation of MdIAAs is critical in auxin signal transduction and root growth regulation in apple.Moreover,our network analysis and high-degree node screening provide a novel research technique for more generally characterizing molecular mechanisms. | Lin Liu Zipeng Yu Yang Xu Cheng Guo Lei Zhang Changai Wu Guodong Yang Jinguang Huang Kang Yan Huairui Shu Chengchao Zheng Shizhong Zhang | 2021 | Journal of Integrative Plant Biology2021，63，4： | 0 |
| 16 | Erratum to:LICOM Model Datasets for the CMIP6 OceanModel Intercomparison ProjectLICOM Model Datasets for the CMIP6 OceanModel Intercomparison Project显示文摘 | Pengfei LIN Zipeng YU Hailong LIU Yongqiang YU Yiwen LI Jinrong JIANG Wei XUE Kangjun CHEN Qian YANG Bowen ZHAO Jilin WEI Mengrong DING Zhikuo SUN Yaqi WANG Yao MENG Weipeng ZHENG Jinfeng MA | 2020 | Advances in Atmospheric Sciences2020，37，6： | 0 |
| 17 | Micro/nanomotor: A promising drug delivery system for cancer therapy显示文摘Micro/nanomotors(MNMs)are small-scale devices that can effectively convert various forms of energy into mechanical motion.Their controllable motility and good permeability have attracted the interest of researchers as promising drug carriers in cancer therapy.Compared with traditional formulations,micro/nanomotor drug delivery systems can greatly improve therapeutic efficiency and reduce the side effects of antitumor drugs.This review mainly discusses the advantages of micro/nanomotor drug delivery systems and the applications of MNMs propelled by exogenous,endogenous,and biohybrid power in cancer therapy.Finally,the main challenges of the applications of micro/nanomotor drug delivery systems,as well as future development trends and opportunities are discussed. | Weihan Zhang Zipeng Zhang Shunli Fu Qingping Ma Yongjun Liu Na Zhang | 2023 | ChemPhysMater2023，2，2： | 0 |
| 18 | Digestive tract reconstruction in pancreaticoduodenectomy in University Hospitals of China: a national questionnaire survey显示文摘Background Pancreaticoduodenectomy(PD)has been widely applied in general hospitals in China;however,there is still a lack of unified standards for each surgical technique and procedure.This survey is intended to investigate the current status of digestive tract reconstruction after PD in university hospitals in China.Method A cross-sectional survey was conducted among the members of the Young Elite Pancreatic Surgery Club of China by using the Questionnaire for Digestive Tract Reconstruction after Pancreaticoduodenectomy.The questionnaire was disseminated and collected by point-to-point communication via WeChat public platforms.Results A total of 73 valid questionnaires were returned from 65 university hospitals in 28 provincial divisions of China's Mainland.The respondents who performed PD surgery with an annual volume of over 100 cases accounted for 63%.Generally,laparoscopic PD was performed less often than open PD.Child and Whipple reconstructions accounted for 70%and 26%,respectively.The sequence of pancreatoenteric,biliary-enteric,and gastrointestinal reconstruction accounted for 84%of cases.In pancreatoenteric anastomosis,double-layer anastomosis is the most commonly employed type,accounting for approximately 67%,while single-layer anastomosis accounts for 30%.Of the double-layer anastomoses,duct-to-mucosa/dunking(94%/4%)PJ was performed with duct-mucosa using the Blumgart method(39%)and Cattel-Warren(29%),with continuous/interrupted sutures in the inner layer(69%/31%)and continuous/interrupted sutures in the outer layer(53%/23%).In single-layer anastomosis,continuous/interrupted sutures accounted for 41%/45%.In hepatojejunostomy,single-layer/double-layer suture accounted for 79%/4%,and continuous/interrupted suture accounted for 75%/9%.Forty-six percent of the responding units had not applied double-layer biliary-intestinal anastomosis in the last 3 years,75%of the responding surgeons chose the anastomosis method according to bile duct diameter,with absorbable/non-absorbable suture accounting for 86%/12%.PD/pylorus-preserving PD accounted for 79%/11%of GJ cases,the distance between GJ and HJ<30 cm,30-50 cm and>50 cm were 11%,75%,and 14%,respectively.Antecolic/retrocolic GJ accounted for 71%/23%of cases.Twenty-two percent of GJ cases employed Braun anastomosis,while 55%and 19%of GJ cases used linear cutting staplers/tube-type staplers,respectively;60%/14%were reinforced/not reinforced via manual suturing after stapler anastomosis.Manual anastomosis in GJ surgery employed absorbable/non-absorbable sutures(91%/9%).Significant differences in reconstruction techniques were detected between different volumes of PD procedures(<100/year and>100/year),regions with different economic development levels,and between north and south China.Conclusion Digestive tract reconstruction following PD exists heterogeneity in Chinese university hospitals.Corresponding prospective clinical studies are needed to determine the consensus on pancreatic surgery that meets the clinical reality in China. | Jishu Wei Qiang Xu Yuhua Zhang Jiabin Jin Xiaodong Tian Qiaofei Liu Zipeng Lu Zheng Wang Shanmiao Gou Song Gao Xianlin Han Yefei Rong Niandong Ji Ye Lin Guolin Li Shi Chen Feng Cao Hua Chen Wenming Wu Yupei Zhao the Young Elite Pancreatic Surgery Club of China | 2022 | Journal of Pancreatology2022，5，3： | 0 |
| 19 | Energy Optimization in Multi-UAV-Assisted Edge Data Collection System显示文摘In the IoT(Internet of Things)system,the introduction of UAV(Unmanned Aerial Vehicle)as a new data collection platform can solve the problem that IoT devices are unable to transmit data over long distances due to the limitation of their battery energy.However,the unreasonable distribution of UAVs will still lead to the problem of the high total energy consumption of the system.In this work,to deal with the problem,a deployment model of a mobile edge computing(MEC)system based on multi-UAV is proposed.The goal of the model is to minimize the energy consumption of the system in the process of data transmission by optimizing the deployment of UAVs.The DEVIPSK(differential evolution algorithm with variable population size based on a mutation strategy pool initialized by K-Means)is proposed to solve the model.In DEVIPSK,the population is initialized by K-Means to obtain better initial positions of UAVs.Besides,considering the limitation of the fixed mutation strategy in the traditional evolutionary algorithm,a mutation strategy pool is used to update the positions of UAVs.The experimental results show the superiority of the DEVIPSK and provide guidance for the deployment of UAVs in the field of edge data collection in the IoT system. | Bin Xu Lu Zhang Zipeng Xu Yichuan Liu Jinming Chai Sichong Qin Yanfei Sun | 2021 | Computers, Materials & Continua2021，，11： | 0 |
| 20 | A feedback regulation between ARF7-mediated auxin signaling and auxin homeostasis involving MES17 affects plant gravitropism显示文摘Gravitropism is an essential adaptive response of land plants.Asymmetric auxin gradients across plant organs,interpreted by multiple auxin signaling components including AUXIN RESPONSE FACTOR7(ARF7),trigger differential growth and bending response.However,how this fundamental process is strictly maintained in nature remains unclear.Here,we report that gravity stimulates the transcription of METHYL ESTERASE17(MES17)along the lower side of the hypocotyl via ARF7-dependent auxin signaling.The asymmetric distribution of MES17,a methyltransferase that converts auxin from its inactive form methyl indole-3-acetic acid ester(MeI AA)to its biologically active form free-IAA,enhanced the gradient of active auxin across the hypocotyl,which in turn reversely amplified the asymmetric auxin responses and differential growth that shape gravitropic bending.Taken together,our findings reveal the novel role of MES17-mediated auxin homeostasis in gravitropic responses and identify an ARF7-triggered feedback mechanism that reinforces the asymmetric distribution of active auxin and strictly controls gravitropism in plants. | Feng Zhang Cuiling Li Xingzhen Qu Jiajia Liu Zipeng Yu Junxia Wang Jiayong Zhu Yongqiang Yu Zhaojun Ding | 2022 | Journal of Integrative Plant Biology2022，64，7： | 0 |
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