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| 1 | Epigenetic Mechanism Involved in the HBV/HCV-Related Hepatocellular Carcinoma Tumorigenesis显示文摘 | Liang Rongrui Huang Na Li Zongfang Ji Fanpu Jiang Shiwen | 2014 | Current Pharmaceutical Design2014，，11： | 2 |
| 2 | Diallyl disulfide induces G2/M arrest and promotes apoptosis throughthe p53/p21 and MEK-ERK pathways in human esophageal squamous cell carcinoma显示文摘 | Xiaoran Yin Rong Zhang Cheng Feng Jun Zhang Dong Liu Kun Xu Xijing Wang Shuqun Zhang Zongfang Li Xinlian Liu Hongbing Ma | 2014 | Oncology Reports2014，，： | 1 |
| 3 | Research on the Allocation of Cash Flow Rights and Control Rights in Venture Capital Financing Contract显示文摘 | Yunfei Li Zongfang Zhou | 2012 | Modern Economy2012，3，1： | 1 |
| 4 | Oxidative Stress Upregulates PDCD4 Expression in Patients with Gastric Cancer via miR-21显示文摘 | Honglei Tu Haibing Sun Yan Lin Jie Ding Kejun Nan Zongfang Li Qiang Shen Yongchang Wei | 2014 | Current Pharmaceutical Design2014，，11： | 1 |
| 5 | GPER in CAFs regulates hypoxia-driven breast cancer invasion in a CTGF-dependentmanner显示文摘 | Juan Ren Hui Guo Huili Wu Tao Tian Danfeng Dong Yuelang Zhang Yanxia Sui Yong Zhang Dongli Zhao Shufeng Wang Zongfang Li Xiaozhi Zhang Rui Liu Jianshneg Qian Hongxia Wei Wenjun Jiang Ya Liu Yi Li | 2015 | Oncology Reports2015，，： | 1 |
| 6 | Research on the Allocation of Cash Flow Rights and Control Rights in Venture Capital Financing Contract显示文摘 | Zongfang Zhou Yunfei Li | 2012 | Modern Economy2012，，01： | 1 |
| 7 | Clinicopathological parameters of cervical cancer based on the expression of p16INK4A proteins显示文摘Objective: To retrospectively analyze the clinical data of 275 cases of cervical cancer (CC) in our hospital, and investigate the clinicopathological parameters of cervical cancer based on the expression of p16INK4A proteins. Methods: The clinical information of 275 patients with cervical cancer were retrospectively analyzed between 2006 and 2011, including the patients' age, clinical FIGO stage, differentiation, histologic grade, infiltration depth, treatment, pathological diagnosis after surgery, and results of following-up.Immunohistochemistry was also done on sections of confirmed cancer specimens without prior chemotherapy/radiotherapy. Results: Among various clinicopathological parameters, the median age was 48 years old. The grade was significantly associated with histological type, HPV infection and with lymph node invasion. FIGO stage was strongly correlated to the infiltration depth and lymph node metastasis. P16INK4A expression was significantly correlated with histologic grade. However, there were no differences between p16INK4A staining and patient's age, histopathology and lymph node metastases. Conclusion: The incidence of cervical cancer becomes increasingly younger. Additionally, p16INK4A can function as a diagnostic marker of cervical carcinomas. | Li Mu Yang Jun SH Boshan Xue Xiang Gao Qing Li Zhaorong Li Zongfang | 2012 | Journal of Medical Colleges of PLA(China)2012，27，5： | 1 |
| 8 | Distinct effect of Chrysanthemum indicum Linné extracts on isoproterenol-inducedgrowth of human hepatocellular carcinoma cells显示文摘 | Aihua Yuan Zongfang Li Xinqiu Li Shanyong Yi Shukui Wang Kaiwang Shi Jianmin Bian | 2009 | Oncology Reports2009，，6： | 1 |
| 9 | Statins suppress MMP2 secretion via inactivation of Rho A/ROCK pathway in pulmonary vascular smooth muscles cells显示文摘 | Manxiang Li Zongfang Li Xiuzhen Sun | 2008 | European Journal of Pharmacology2008，591，3： | 1 |
| 10 | Research on the alloca- tion of cash flow rights and control rights in venture capital financing contract 显示文摘 | YUNFEI LI ZONGFANG ZHOU | 2012 | Modern Economy2012，，3： | 1 |
| 11 | Splenectomy prior to antiviral therapy in patients with hepatitis C virus related decompensated cirrhosis显示文摘 | Fanpu Ji Shu Zhang Na Huang Hong Deng Zongfang Li | 2013 | Brazilian Journal of Infectious Diseases2013，，： | 1 |
| 12 | 用双旋转磁场理论分析罩极电动机性能显示文摘通过对罩极电动机的两个旋转磁场的分析,推导出总的电磁转矩公式,利用该公式就可得出罩极电动机的运行特性曲线,并计算其输入、输出功率、效率、功率因数等,文中提出的方法解决了罩极电动机由于结构复杂而难以进行完整的定量分析的问题。 | Li Zongfang (School of Electric Eng., Southwest Jiaotong University, Chengdu 610031, China) | 1998 | 西南交通大学学报1998，33，3： | 1 |
| 13 | Reduced syncytin-1 expression in choriocarcinoma BeWo cells activates the calpain1–AIF-mediated apoptosis, implication for preeclampsia显示文摘 | Qiang Huang Haibin Chen Fengchao Wang Brian C. Brost Jinping Li Yu Gao Zongfang Li Ya Gao Shi-Wen Jiang | 2014 | Cellular and Molecular Life Sciences2014，，16： | 1 |
| 14 | Synchronous adenocarcinoma and mucosal-associated lymphoid tissue lymphoma of the stomach显示文摘Multiple occurrences of primary gastric neoplasma are relatively well known,but few reports have been published regarding the simultaneous presence of gastric carcinoma and gastric malignant lymphoma.A previous study reported that the incidence of coexisting primary malignant lymphoma and adenocarcinoma of the stomach was 0.08% (two of 2 438 adenocarcinoma cases).1 Moreover,most of the adenocarcinomas were smaller and penetrated less than coexisting mucosal-associated lymphoid tissue (MALT) lymphoma.Here,we report a case of synchronous adenocarcinoma and MALT lymphoma of the stomach,but the lesion with lymphoma was focal and smaller than that of adenocarcinoma in size. | Bu Wangjun Pei Honghong Li Liang Li Zongfang | 2014 | Chinese Medical Journal2014，，7： | 0 |
| 15 | Teabase:A comprehensive omics database of Camellia显示文摘Dear Editor,Camellia is an economically important genus that has been highly valued throughout many years of human history.It encompasses various species,including tea plants(Camellia sect.Thea),the ornamental garden plant Camellia japonica,and the oil-seed crop Camellia oleifera(Macfarlane,2004).Despite the long cultivation history of some Camellia species worldwide,we had a limited understanding of their genetic variation until the end of the 20th century,when developments in genomics and sequencing technologies emerged. | Xuzhen Li Zongfang Shen Cheng Ma Ling Yang Shengchang Duan Yangmei Lv Ling Yang Yahui Lei Yang Dong Jun Sheng | 2023 | Plant Communications2023，4，5： | 0 |
| 16 | Exogenous p16 gene therapy combined with X-ray irradiation suppresses the growth of human glioma cells显示文摘In this study, we infected human glioma U251 cells with a replication-defective recombinant adeno-virus carrying the p16 gene. This adenovirus constructed was able to transfect exogenous p16 into the human glioma cells efficiently, and direct a high level of p16 protein expression. Tumor-inhibition experiments demonstrated that treatment with the adenovirus-p16 significantly inhibited the growth of glioma cells in vitro as well as the in vivo development of tumors in nude mice bearing a brain glioma. The combination of adenovirus-p16 gene treatment and X-ray irradiation resulted in a greater inhibition of tumor growth. Adenovirus-mediated p16 gene therapy conferred a significant antitumor effect against human glioma cells both in vitro and in vivo, and that there was a synergistic effect when X-ray irradiation was also used. | Hongbing Ma Zhengli Di Minghua Bai Hongtao Ren Zongfang Li | 2011 | Neural Regeneration Research2011，6，34： | 0 |
| 17 | The effect of spleen on the change of Treg cells during mouse pregnancy显示文摘Objective:To analyze the effect of spleen on the Treg cells during pregnancy. Methods: The mononuclear cells were separated from the peripheral, spleen and uterus or placenta blood. Flow cytometry was employed to analyze the percent of Treg cells in total T cells in different stages of pregnancy. Immunohistochemical staining was used to make sure the distribution of Treg in spleen in different stages of pregnancy. Results: The results of immunohistochemical staining showed that compared with spleen Treg cells in normal unpregnant mice, spleen Treg cells on day 7 and 14 of pregnancy significantly increased. After splenectomy, peripheral blood and placenta Treg cells on day 7 of pregnancy markedly decreased as compared with the normal pregnancy(P<0.01). And the cells on day 14of pregnancy were markedly recovered as compared with the normal pregnancy. Conclusion: Our study indicated that the spleen and its Treg cells might play important roles in transient tolerance during pregnancy. | GAO Qing LI Mu ZHANG Shu ZHOU Rui WU Jinfang LI Zongfang | 2013 | Journal of Medical Colleges of PLA(China)2013，28，5： | 0 |
| 18 | Fibrillarin promotes homologous recombination repair by facilitating the recruitment of recombinase RAD51 to DNA damage sites显示文摘Eukaryotic organisms constantly face a wide range of internal and external factors that cause damage to their DNA.Failure to accurately and efficiently repair these DNA lesions can result in genomic instability and the development of tumors(Canela et al.,2017).Among the various forms of DNA damage,DNA doublestrand breaks(DSBs)are particularly harmful.Two major pathways,non-homologous end joining(NHEJ)and homologous recombination(HR),are primarily responsible for repairing DSBs(Katsuki et al.,2020;Li and Yuan,2021;Zhang and Gong,2021;Xiang et al.,2023).NHEJ is an error-prone repair mechanism that simply joins the broken ends together(Blunt et al.,1995;Hartley et al.,1995). | Yanhua MU Jinhua HAN Mingjie WU Zongfang LI Ke DU Yameng WEI Mengjie WU Jun HUANG | 2023 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2023，24，12： | 0 |
| 19 | Chrysanthemum indicum linné extracts attenuate the mitogenic effect of epinephrine on human HCC cells显示文摘Objective: To investigate the stimulatory effect of epinephrine(Epi) and the antagonistic effect of Chrysanthemum indicum Linné extracts (CILE) on Epi-induced growth of human hepatocellular carcinoma(HCC) cells. Methods: The stimulatory effect of Epi and inhibitory effect of CILE on the growth of HepG2 and MHCC97H cells were investigated using a proliferation assay in correlation with βadrenergic receptor(β 2-AR) blockade, a MEK1/MEK2 inhibitor, and assessment of MAPK/ERK1/2 intracellular activity. Results: Epi transiently activated MAPK/ERK1/2 in HepG2 and MHCC97H cells, resulting in a burst of growth. The effect of Epi was significantly attenuated by ICI 118551 and U0126. CILE exhibited a dose-dependent attenuation of the stimulatory effect of Epi on the growth of both cell lines and inhibited the Epi-induced activation of MAPK/ERK1/2. Conclusion: Epi, mimicking a mitogen, stimulated the growth of HepG2 and MHCC97H cells, and CILE was effective in attenuating this effect of Epi on tumor cells by inhibiting the β2-AR-mediated activation of MAPK/ERK1/2. | Aihua Yuan Zongfang Li Xinqiu Li Shanyong Yi Shukui Wang Kaiwang Shi Jianmin Bian | 2009 | Journal of Nanjing Medical University2009，23，4： | 0 |
| 20 | Simulation of hemodynamics in portal vein hypertension using CFD显示文摘Introduction Liver cirrhosis generally occurs with the hemodynamic changes during the portal vein hypertension and finally leads to the atrophy of the right lobe of the liver and hepatic failure[1].According to the hemodynamic changes,a hypothesis has been proposed that the liver volume is related to the istribution of blood from the splenic vein(SV)that involves nutrition from spleen and pancreas[2,3].The objective of the present paper is to simulate the blood flow in real models of portal vein hypertension and validate the hypothesis using computational fluid dynamics(CFD)method.Methods This study includes 2 patients with liver cirrhosis and a set of 4 normal subjects. | Xiao Li Yansong Pu Peng Nie Zongfang Li Bin Chen | 2013 | 医用生物力学2013，28，S1： | 0 |
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