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| 1 | Activation of gibberellin 2-oxidase 6 decreases active gibberellin levels and creates a dominant semi-dwarf phenotype in rice (Oryza sativa L.)显示文摘Gibberellin (GA) 2-oxidase plays a key role in the GA catabolic pathway through 2β-hydroxylation.In the present study,we isolated a CaMV 35S-enhancer activation tagged mutant,H032.This mutant exhibited a dominant dwarf and GA-deficient phenotype,with a final stature that was less than half of its wild-type counterpart.The endogenous bioactive GAs are markedly decreased in the H032 mutant,and application of bioactive GAs (GA3 or GA4) can reverse the dwarf phenotype.The integrated T-DNA was detected 12.8 kb upstream of the OsGA2ox6 in the H032 genome by TAIL-PCR.An increased level of OsGA2ox6 mRNA was detected at a high level in the H032 mutant,which might be due to the enhancer role of the CaMV 35S promoter.RNAi and ectopic expression analysis of OsGA2ox6 indicated that the dwarf trait and the decreased levels of bioactive GAs in the H032 mutant were a result of the up-regulation of the OsGA2ox6 gene.BLASTP analysis revealed that OsGA2ox6 belongs to the class III of GA 2-oxidases,which is a novel type of GA2ox that uses C20-GAs (GA12 and/or GA53) as the substrates.Interestingly,we found that a GA biosynthesis inhibitor,paclobutrazol,positively regulated the OsGA2ox6 gene.Unlike the over-expression of OsGA2ox1,which led to a high rate of seed abortion,the H032 mutant retained normal flowering and seed production.These results indicate that OsGA2ox6 mainly affects plant stature,and the dominant dwarf trait of the H032 mutant can be used as an efficient dwarf resource in rice breeding. | Jian Huang Ding Tang Yi Shen Baoxiang Qin Lilan Hong Aiqing You Ming Li Xin Wang Hengxiu Yu Minghong Gu Zhukuan Cheng | 2010 | Journal of Genetics and Genomics2010，37，1： | 36 |
| 2 | The Belt and Road:Geographical pattern and regional risks显示文摘Building the Belt and Road is initiatives of China to promote win-win international cooperation in the new era,aiming at green,health,intellect and peace and the joint developme nt with people of the coun tries along the route.Systematic an alysis on envir on mental characteristics,evolutionary tendency and future risks are certainly the scie ntific fun dame ntals of sustainable development for the Belt and Road construction.Applied remote sensing monitoring,statistical analysis,this paper investigates the regional characteristics of climate,topography,soil,hydrology,vegetation cover and terrestrial ecosystems production,as well as socio-economic conditions.Based on the regional characteristics,the Belt and Road is divided into 9 sub-regions:Central and Eastern Europe sub-region with cold and humid climate,Mongolia and Russia sub-region with cold and arid climate,Central and West Asia arid sub-region,Southeast Asia sub-region with warm and humid climate,Pakistan arid sub-region,Bangladesh-India-Myanmar sub-region with warm and humid climate,Eastern China monsoon sub-region,Northwest China arid sub-region and Tibetan Plateau sub-region.Combining modeling simulation with seenario projections,natural disaster assessment methodology is used to assess the risk of extreme events including heat waves,droughts and floods in the coming 30 years(2021-2050).Results show that,on the basis of the regional framework,the western Eurasia would be a warming trend;both sides of Qinghai-Tibet Plateau in high temperature and heat waves risk;Central and Eastern Europe sub-region with cold and humid climate in high drought risk;Bangladesh-lndia-Myanmar sub-region with warm and humid climate as well as Eastern China in high risk of flooding. | WU Shaohong LIU Lulu LIU Yanhua GAO Jiangbo DAI Erfu FENG Aiqing WANG Wentao | 2019 | Journal of Geographical Sciences2019，29，4： | 11 |
| 3 | From Green Super Rice to green agriculture:Reaping the promise of functional genomics research显示文摘Producing sufficient food with finite resources to feed the growing global population while having a smaller impact on the environment has always been a great challenge.Here,we review the concept and practices of Green Super Rice(GSR)that have led to a paradigm shift in goals for crop genetic improvement and models of food production for promoting sustainable agriculture.The momentous achievements and global deliveries of GSR have been fueled by the integration of abundant genetic resources,functional gene discoveries,and innovative breeding techniques with precise gene and whole-genome selection and efficient agronomic management to promote resource-saving,environmentally friendly crop production systems.We also provide perspectives on new horizons in genomic breeding technologies geared toward delivering green and nutritious crop varieties to further enhance the development of green agricul-ture and better nourish the world population. | Sibin Yu Jauhar Ali Shaochuan Zhou Guangjun Ren Huaan Xie Jianlong Xu Xinqiao Yu Fasong Zhou Shaobing Peng Liangyong Ma Dingyang Yuan Zefu Li Dazhou Chen Ruifeng Zheng Zhigang Zhao Chengcai Chu Aiqing You Yu Wei Susong Zhu Qiongyao Gu Guangcun He Shigui Li Guifu Liu Changhua Liu Chaopu Zhang Jinghua Xiao Lijun Luo Zhikang Li Qifa Zhang | 2022 | Molecular Plant2022，15，1： | 6 |
| 4 | Parallel implementation of fast multipole method based on JASMIN显示文摘Fast multipole method (FMM) may reduce the complexity of N-body problems from O(N 2 ) to O(N log N) or O(N).It was applied in problems ranging from electromagnetic scattering to dislocation dynamics.FMM can be divided into two parts: commonness and individuality.A parallel solver of FMM commonly used in various applications has been designed and implemented in JASMIN infrastructure.The solver encapsulates the commonness.Furthermore,it supplies users with abstract interfaces required to implement the individuality with serial mode.The commonness contains distributed storage of multi-levels,intra-level and inter-level data communication,and arrangement of computation,etc.The individuality contains various expansion and translation operators.We give here two applications that have used the solver.Scalability was demonstrated with a parallel efficiency above 80% on 1024 processors. | CAO XiaoLin MO ZeYao LIU Xu XU XiaoWen ZHANG AiQing | 2011 | Science China(Information Sciences)2011，54，4： | 5 |
| 5 | Integral Barrier Lyapunov function-based adaptive control for switched nonlinear systems显示文摘This paper presents an adaptive control method for a class of uncertain strict-feedback switched nonlinear systems. First, we consider the constraint characteristics in the switched nonlinear systems to ensure that all states in switched systems do not violate the constraint ranges. Second, we design the controller based on the backstepping technique, while integral Barrier Lyapunov functions(i BLFs) are adopted to solve the full state constraint problems in each step in order to realize the direct constraints on state variables.Furthermore, we introduce the Lyapunov stability theory to demonstrate that the adaptive controller achieves the desired control goals. Finally, we perform a numerical simulation, which further verifies the significance and feasibility of the presented control scheme. | Lei LIU Yan-Jun LIU Aiqing CHEN Shaocheng TONG C.L.Philip CHEN | 2020 | Science China(Information Sciences)2020，63，3： | 5 |
| 6 | Molecular analysis of the chloroplast Cu/Zn-SOD gene(AhCSD2) in peanut显示文摘Superoxide dismutase(SOD, EC 1.15.1.1) plays a key role in response to drought stress, and differences in SOD activity changes among cultivars are important under drought conditions. We obtained the full-length DNA of the chloroplast Cu/Zn-SOD gene(Ah CSD2)from 11 allotetraploid cultivars and 5 diploid wild species in peanut. BLAST search against the peanut genome showed that the Ah CSD2 genes g CSD2-1 and g CSD2-2 are located at the tops of chromosome A03(A genome) and B03(B genome), respectively, and both contain 8exons and 7 introns. Nucleotide sequence analyses indicated that g CSD2-2 sequences were identical among all the tested cultivars, while g CSD2-1 sequences showed allelic variations.The amino acid sequences deduced from g CSD2-1 and g CSD2-2 both contain a chloroplast transit peptide and are distinguished by 6 amino acid(aa) residue differences. The other 2aa residue variations in the mature peptide regions give rise to three-dimensional structure changes of the protein deduced from the genes g CSD2-1 and g CSD2-2. Sequences analyses of cultivars and wild species showed that g CSD2-2 of Arachis hypogaea and g Aip CSD2(Arachis ipaensis) are identical, and despite the abundant polymorphic loci between g CSD2-1 of A.hypogaea and sequences from A genome wild species, the deduced amino acid sequence of Ah CSD2-1(A. hypogaea) is identical to that of Adu CSD2(Arachis duranensis), whereas Aco CSD2(Arachis correntina) and Aca CSD2(Arachis cardenasii) both have 2 aa differences in the transit peptide region compared with Ah CSD2-1(A. hypogaea). Based on the Peanut Genome Project, promoter prediction revealed many stress-related cis-acting elements within the potential promoter regions(pp-A and pp-B). pp-A contains more binding sites for drought-associated transcriptional factors than pp-B. We hypothesize that the marked changes in SOD activity in different cultivars under drought stress are tightly regulated by transcription factors through transcription and expression of Ah CSD2 genes. | Xiurong Zhang Qian Wan Fengzhen Liu Kun Zhang Aiqing Sun Bing Luo Li Sun Yongshan Wan | 2015 | The Crop Journal2015，3，3： | 4 |
| 7 | Engineering rock mechanics practices in the underground powerhouse at JinpingⅠhydropower station显示文摘Based on the analyses of data obtained from the underground powerhouse at Jinping Ⅰ hydropower station,a comprehensive review of engineering rock mechanics practice in the underground powerhouse is first conducted.The distribution of strata,lithology,and initial geo-stress,the excavation process and corresponding rock mass support measures,the deformation and failure characteristics of the surrounding rock mass,the stress characteristics of anchorage structures in the cavern complex,and numerical simulations of surrounding rock mass stability and anchor support performance are presented.The results indicate that the underground powerhouse of Jinping Ⅰ hydropower station is characterized by high to extremely high geo-stresses during rock excavation.Excessive surrounding rock mass deformation and high stress of anchorage structures,surrounding rock mass unloading damage,and local cracking failure of surrounding rock masses,etc.,are mainly caused by rock mass excavation.Deformations of surrounding rock masses and stresses in anchorage structures here are larger than those found elsewhere:20%of extensometers in the main powerhouse record more than 50 mm with the maximum at around 250 mm observed in the downstream sidewall of the transformer hall.There are about 25%of the anchor bolts having recorded stresses of more than 200 MPa.Jinping Ⅰ hydropower plant is the first to have an underground powerhouse construction conducted in host rocks under extremely high geo-stress conditions,with the ratio of rock mass strength to geo-stress of less than 2.0.The results can provide a reference to underground powerhouse construction in similar geological conditions. | Aiqing Wu Jimin Wang Zhong Zhou Shuling Huang Xiuli Ding Zhihong Dong Yuting Zhang | 2016 | Journal of Rock Mechanics and Geotechnical Engineering2016，8，5： | 4 |
| 8 | A linearly-independent higher-order extended numerical manifold method and its application to multiple crack growth simulation显示文摘The numerical manifold method(NMM)can be viewed as an inherent continuous-discontinuous numerical method,which is based on two cover systems including mathematical and physical covers.Higher-order NMM that adopts higher-order polynomials as its local approximations generally shows higher precision than zero-order NMM whose local approximations are constants.Therefore,higherorder NMM will be an excellent choice for crack propagation problem which requires higher stress accuracy.In addition,it is crucial to improve the stress accuracy around the crack tip for determining the direction of crack growth according to the maximum circumferential stress criterion in fracture mechanics.Thus,some other enriched local approximations are introduced to model the stress singularity at the crack tip.Generally,higher-order NMM,especially first-order NMM wherein local approximations are first-order polynomials,has the linear dependence problems as other partition of unit(PUM)based numerical methods does.To overcome this problem,an extended NMM is developed based on a new local approximation derived from the triangular plate element in the finite element method(FEM),which has no linear dependence issue.Meanwhile,the stresses at the nodes of mathematical mesh(the nodal stresses in FEM)are continuous and the degrees of freedom defined on the physical patches are physically meaningful.Next,the extended NMM is employed to solve multiple crack propagation problems.It shows that the fracture mechanics requirement and mechanical equilibrium can be satisfied by the trial-and-error method and the adjustment of the load multiplier in the process of crack propagation.Four numerical examples are illustrated to verify the feasibility of the proposed extended NMM.The numerical examples indicate that the crack growths simulated by the extended NMM are in good accordance with the reference solutions.Thus the effectiveness and correctness of the developed NMM have been validated. | Dongdong Xu Aiqing Wu Cong Li | 2019 | Journal of Rock Mechanics and Geotechnical Engineering2019，11，6： | 4 |
| 9 | Cloning and characterization of rice RH3 gene induced by brown planthopper显示文摘Experiments have showed that the histone H3 gene is correlated with development, cell speciality and stress response. The RH3 full-length cDNA was isolated from the cDNA library of rice infested by brown planthopper (BPH) with EST (Accession no. BU572343) screened from rice SSH library as probe. This gene encodes histone H3 protein in-cluding 136 amino acids, with one amino acid different from a kind of disease resistance-related protein in rice (AF467728). At the position 126, the aspartic acid is replaced by lysine. The time course results showed that the expression of the RH3 began to increase at 8 h after BPH-feeding, and got to its peak at 96 h. Regulations of the gene expression in treatments with stress/defense signal molecules were ana-lyzed by Northern blot. Water deficit and Pyricularia grisea increased the expression of RH3 while ABA down-regulated the gene. The enhanced accumulation of RH3 transcripts in the vascular bundle and short cell of stem after BPH feeding was revealed by RNA in situ hybridization. It is the first time to report that RH3 is correlated with the response of rice to BPH. | Xiaolan Wang Qingmei Weng Aiqing You Lili Zhu Guangcun He | 2003 | Chinese Science Bulletin2003，48，18： | 3 |
| 10 | Chinese herbal medicine for chronic heart failure:a multicenter,randomized,double-blind,placebo-controlled trial显示文摘Objective:The purpose of this study was to assess the efficacy and safety of Chinese herbal medicine(CHM)in the treatment of chronic heart failure(CHF)patients according to syndrome differentiation.Methods:In this multicenter,randomized,double-blind,placebo-controlled clinical trial,a total of 220 CHF patients were assigned to receive CHM or placebo granules without decoction according to syndrome differentiation in addition to their standard western treatment for 4 weeks.The change in the left ventricular ejection fraction(LVEF)was the primary outcome,and the changes in the TCM syndrome scores(TCM-SS)and New York Heart Association functional classification(NYHA-FC)were the secondary outcomes. | Liangtao Luo Juan Wang Aiqing Han Peng Zhang Shuzhen Guo Chan Chen Xuegong Xu Qian Lin Huihui Zhao Wei Wang | 2014 | Journal of Traditional Chinese Medical Sciences2014，1，2： | 3 |
| 11 | Preparation and properties of gel membrane containing porous PVDF-HFP matrix and cross-linked PEG for lithium ion conduction显示文摘Lithium ion conducting membranes are the key materials for lithium batteries.The lithium ion conducting gel polymer electrolyte membrane(Li-GPEM)based on porous poly(vinylidene fluoride-co-hexafluoropropylene)(PVDF-HFP)matrix and cross-linked PEG network is pre-pared by a typical phase inversion process.By immersing theporousPVDF-HFPmembraneinliquidelectrolytecon-taining poly(ethylene glycol)diacrylate(PEGDA)and an initiator to absorb the liquid electrolyte at 25℃,and then thermally cross-linking at 60℃,the Li-GPEM is fabricated successfully.The measurements on its weight loss,mech-anical and electrochemical properties reveal that the obtained Li-GPEM has better overall performance than the liquid and blend gel systems used as conductive media in lithium batteries.The ionic conductivity of the fabricated Li-GPEM can reach as high as 2.25×10^(-3) S/cm at 25℃. | Mei ZHANG Aiqing ZHANG Zhenyu CUI Baoku ZHU Gaige HAN Youyi XU | 2008 | Frontiers of Chemical Science and Engineering2008，2，1： | 3 |
| 12 | Delineating spatiotemporal and hierarchical development of human fetal innate lymphoid cells显示文摘Whereas the critical roles of innate lymphoid cells(ILCs)in adult are increasingly appreciated,their developmental hierarchy in early human fetus remains largely elusive.In this study,we sorted human hematopoietic stem/progenitor cells,lymphoid progenitors,putative ILC progenitor/precursors and mature ILCs in the fetal hematopoietic,lymphoid and non-lymphoid tissues,from 8 to 12 post-conception weeks,for single-cell RNA-sequencing,followed by computational analysis and functional validation at bulk and single-cell levels.We delineated the early phase of ILC lineage commitment from hematopoietic stem/progenitor cells,which mainly occurred in fetal liver and intestine.We further unveiled interleukin-3 receptor as a surface marker for the lymphoid progenitors in fetal liver with T,B,ILC and myeloid potentials,while IL-3RA–lymphoid progenitors were predominantly B-lineage committed.Notably,we determined the heterogeneity and tissue distribution of each ILC subpopulation,revealing the proliferating characteristics shared by the precursors of each ILC subtype.Additionally,a novel unconventional ILC2 subpopulation(CRTH2–CCR9+ILC2)was identified in fetal thymus.Taken together,our study illuminates the precise cellular and molecular features underlying the stepwise formation of human fetal ILC hierarchy with remarkable spatiotemporal heterogeneity. | Chen Liu Yandong Gong Han Zhang Hua Yang Yang Zeng Zhilei Bian Qian Xin Zhijie Bai Man Zhang Jian He Jing Yan Jie Zhou Zongcheng Li Yanli Ni Aiqing Wen Yu Lan Hongbo Hu Bing Liu | 2021 | Cell Research2021，31，10： | 2 |
| 13 | SOME RESULTS OF UPPER ATMOSPHERIC COMPOSITION MEASUREMENTS BY A MASS-SPECTROMETER ON BOARD 'SZ-2':CHANGE OF COMPOSITIONS DURING SOLAR AND GEOMAGNETIC DISTURBANCES显示文摘Upper atmosphere composition data were obtained for the last half year with a quadruple mass spectrometer on board spacecraft 'SZ-2' launched on 10 Jan uary 2001. Based on the analysis of these data, the variations of atmospheric compositions in solar and geomagnetic quiet conditions are reported first, then a detailed discussion on the atmospheric composition variations under the so lar and geomagnetic disturbed conditions is given. The results show that near the altitude of 400 km the variations of main atmospheric compositions corre sponding to solar disturbances are more remarkable in the sunlit area than in the shade area. On the contrary, in geomagnetic disturbance events the corre sponding variations are more obvious in the shade area, an evident increase of N2 density at relatively higher latitudes was observed. | QIN Guotai QIU Shiyan HE Aiqing ZHU Yiqiang SUN Lilin LIN Xianwen LI Hong XU Xuepei | 2002 | 空间科学学报2002，22，z1： | 2 |
| 14 | JASMIN: a parallel software infrastructure for scientific computing显示文摘 | Zeyao Mo Aiqing Zhang Xiaolin Cao Qingkai Liu Xiaowen Xu Hengbin An Wenbing Pei Shaoping Zhu | 2010 | Frontiers of Computer Science in China2010，，4： | 2 |
| 15 | Key rock mechanical problems of underground powerhouse in Shuibuya hydropower station显示文摘The complicated rock structures and the stability of surrounding rocks of the underground powerhouse were the key rock mechanical problems in Shuibuya hydropower station.In order to overcome the related rock mechanical problems encountered during its construction,a comprehensive research was carried out for the underground powerhouse in Shuibuya hydropower station based on a detailed geological survey.It covers the investigations on the initial in-situ stress distribution features,rock mechanical properties,engineering rock mass classifications by different methods,numerical modeling for stability and support analysis,proper measures for rock excavation and support.The results show that the rock excavations of the underground powerhouse under the given geological conditions can be controlled effectively.Some measures,suggested by the designers,are proved to be rational and effective.These measures mainly consist of:(1) the soft rock replacements by concrete in local area below the crane beam,(2) the shotcrete and reinforcement by rock bolts and anchor cables in surrounding rocks,and (3) 2 m concrete placement on the rock bench between adjacent tailrace tubes.The engineering practice shows that the treated surrounding rocks have a good overall stability.The deformation behaviors observed by safety equipments are within the designing limits.The research conclusions on the related rock mechanical problems,prior to the underground powerhouse excavations,are reliable. | Aiqing Wu1,Qigui Yang2,Xiuli Ding1,Huoming Zhou1,Bo Lu1 1 Key Laboratory of Geotechnical Mechanics and Engineering of Ministry of Water Resources,Yangtze River Scientific Research Institute,Wuhan 430010,China 2 Changjiang Institute of Survey,Planning,Design and Research,Wuhan,430010,China | 2011 | Journal of Rock Mechanics and Geotechnical Engineering2011，3，1： | 2 |
| 16 | G-design of six points and seven edges显示文摘 | Xu Aiqing | 2003 | Journal of Nanjing Normal Uiversity2003，26，： | 2 |
| 17 | Robust reliable guaranteed cost control for nonlinear singular stochastic systems with time delay显示文摘To study the design problem of robust reliable guaranteed cost controller for nonlinear singular stochas-tic systems,the Takagi-Sugeno (T-S) fuzzy model is used to represent a nonlinear singular stochastic system with norm-bounded parameter uncertainties and time delay.Based on the linear matrix inequality (LMI) techniques and stability theory of stochastic differential equations,a stochastic Lyapunov function method is adopted to design a state feedback fuzzy controller.The resulting closed-loop fuzzy system is robustly reliable stochastically stable,and the corresponding quadratic cost function is guaranteed to be no more than a certain upper bound for all admissible uncertainties,as well as different actuator fault cases.A suffcient condition of existence and design method of robust reliable guaranteed cost controller is presented.Finally,a numerical simulation is given to illustrate the effectiveness of the proposed method. | Zhang Aiqing Fang Huajing | 2008 | Journal of Systems Engineering and Electronics2008，19，4： | 2 |
| 18 | G-design with six vertices and seven deges显示文摘 | Xu Aiqing | | to appear0，，： | 2 |
| 19 | Failure mode and effect analysis in blood transfusion: a proactive tool to reduce risks显示文摘 | Yao Lu Fang Teng Jie Zhou Aiqing Wen Yutian Bi | 2013 | Transfusion2013，，12： | 1 |
| 20 | Development of Single Chip Microcomputer Coahnine Safe Monitor System显示文摘 | Gao Wenhua Yan Aiqing | 2005 | The Journal of the Acoustical Society of America2005，33，34： | 1 |
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