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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | Astragaloside IV attenuates free fatty acid-induced ER stress and lipid accumulation in hepatocytes via AMPK activation显示文摘尽管非酒精的脂肪肝疾病(NAFLD ) 的致病完全没被理解,进肝和导致船边交货的肝的 endoplasmic 蜂窝胃的免费的丰满的酸(船边交货) 的增加的流入(嗯) 应力是在 NAFLD 的开始和开发的二关键病原的进程。在这研究,我们调查了 astragaloside IV (AS-IV ) 的效果,从 Astragali 根值净化的 bioactive 混合物,在在 hepatocytes 和阐明的位于 \O 下面机制的导致船边交货的类脂化合物累积上。人的 HepG2 房间和主要鼠科的 hepatocytes 暴露于船边交货(1 mmol/L, oleate/palmitate, 2:1 比率) 与或没有为 24 h 的 AS-IV。到船边交货的暴露在 hepatocytes 导致了显著类脂化合物累积,而有 AS-IV (100 g/mL ) 的合作处理显著地稀释了这现象。尤其是, AS-IV (50-200 g/mL ) concentration-dependently 提高了 AMPK, acetyl-CoA carboxylase (ACC ) 和 SREBP-1c 的 phosphorylation,禁止了累积,成熟 SREBP-1 并且随后的原子 translocation 减少了包括 acc1,船边交货和 scd1 的 lipogenic 基因的 mRNA 层次。AS-IV 处理 concentration-dependently 也稀释了导致船边交货肝嗯应力由关键标记, GRP78,砍和 p 津贴的减小证实了。Pretreated 有 AMPK 禁止者混合物 C (20 mol/L ) 的房间极大地减少了 AS-IV 的这些有益的效果。我们的结果证明 AS-IV 稀释导致船边交货嗯以在 hepatocytes 的一种 AMPK 依赖的方式的压力和类脂化合物累积,它为肝的脂肪变性作为有希望的治疗学支持它的使用。 | Bing ZHOU Dan-li ZHOU Xiao-hong WEI Rong-yu ZHONG Jie XU Liao SUN | 2017 | Acta Pharmacologica Sinica2017，38，7： | 29 |
| 3 | Synthesis and Anticancer Effect of gem-Difluoromethylenated Chrysin Derivatives显示文摘Ten gem-difluoromethylenated chrysin derivatives were prepared and their anticancer activities in vitro were evaluated by the standard MTT method. The results of biological test showed that some of gem-difluoromethylenated chrysin derivatives had higher anticancer activity than chrysin. | Xing ZHENG Jian Guo CAO Duan Fang LIAO Bing Yang ZHU Hui Ting LIU | 2006 | Chinese Chemical Letters2006，17，11： | 20 |
| 4 | Endoscopic thyroidectomy: an evidence-based research on feasibility, safety and clinical effectiveness显示文摘背景内视镜的甲状腺切除的可行性和安全被出版研究的系统的评论的一条途径在过去的 decade.Methods 评估寻找的一个数据库在 MEDLINE 上被执行,系统的评论的 Cochrane 数据库,医生杂志俱乐部的美国学院,效果的评论的摘要的数据库,控制试用的 Cochrane 中央收款机。关于内视镜的甲状腺切除的比较级和非比较的研究被选择并且分析。为比较研究, RevMan 4.2 被用于统计分析;并且为非比较的研究,数据分析被七比较级学习包含 367 个病人的社会科学统计套装软体 13.0 .Results 执行(帮助录像的甲状腺切除(大桶) , 174 个病人;常规甲状腺切除(CT ) , 193 个病人) 在 VAT-CT 被包括组。年龄,性,起作用的类型,和病理学的诊断是类似的。与 CT 相比,大桶的吝啬的起作用的时间显著地更长(大桶, 80.0 分钟;CT, 61.9 分钟, P < 0.01 ) ,但是手术后的医院停留更短(大桶, 1.7 天;CT, 2.5 天, P < 0.01 ) 。为大桶的复杂并发症率是 6.9% ,当那为 CT 是 9.3% 时(P=0.35 ) 。三研究分析了手术后的疼痛和化妆评估,并且显示 VAT 组比 CT 组优异,但是在元分析以后没有重要差别。包含 273 个病人的三比较研究(完全内视镜的甲状腺切除(TET ) , 145 个病人;CT, 128 个病人) 在 TET-CT 组被包括,结果通常类似于 VAT-CT 的组。有 18 和 14 非比较的研究,分别地报导大桶和 TET 的结果。大桶的吝啬的起作用的时间与为 TET 的 135.8 分钟相比是 76.8 分钟。手术后的医院停留分别地是为大桶和 TET 的 1.8 和 3.8 天。到为大桶和 TET 的开的外科的变换的率是类似的(大桶, 2.8% ;TET, 3.9% , P=0.105 ) 。为大桶的复杂并发症率是 8.6% ,当那为 TET 是 3.5% 时(P < 0.01 ) 。内视镜的甲状腺切除的可行性和安全开始被验证并且接受的结论,并且它应该被看作一种有效选择,以化妆结果和手术后的悲痛把一些优点提供给病人。 | CHEN Xiao-dong PENG Bing GONG Ri-xiang WANG Li LIAO Bo LI Chun-lin | 2008 | Chinese Medical Journal2008，，20： | 19 |
| 5 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 6 | Meningeal lymphatic vessels regulate brain tumor drainage and immunity显示文摘Recent studies have shown that meningeal lymphatic vessels(MLVs),which are located both dorsally and basally beneath the skull,provide a route for draining macromolecules and trafficking immune cells from the central nervous system(CNS)into cervical lymph nodes(CLNs),and thus represent a potential therapeutic target for treating neurodegenerative and neuroinflammatory diseases.However,the roles of MLVs in brain tumor drainage and immunity remain unexplored.Here we show that dorsal MLVs undergo extensive remodeling in mice with intracranial gliomas or metastatic melanomas.RNA-seq analysis of MLV endothelial cells revealed changes in the gene sets involved in lymphatic remodeling,fluid drainage,as well as inflammatory and immunological responses.Disruption of dorsal MLVs alone impaired intratumor fluid drainage and the dissemination of brain tumor cells to deep CLNs(dCLNs).Notably,the dendritic cell(DC)trafficking from intracranial tumor tissues to dCLNs decreased in mice with defective dorsal MLVs,and increased in mice with enhanced dorsal meningeal lymphangiogenesis.Strikingly,disruption of dorsal MLVs alone,without affecting basal MLVs or nasal LVs,significantly reduced the efficacy of combined anti-PD-1/CTLA-4 checkpoint therapy in striatal tumor models.Furthermore,mice bearing tumors overexpressing VEGF-C displayed a better response to anti-PD-1/CTLA-4 combination therapy,and this was abolished by CCL21/CCR7 blockade,suggesting that VEGF-C potentiates checkpoint therapy via the CCL21/CCR7 pathway.Together,the results of our study not only demonstrate the functional aspects of MLVs as classic lymphatic vasculature,but also highlight that they are essential in generating an efficient immune response against brain tumors. | Xueting Hu Qiuping Deng Lu Ma Qingqing Li Yidong Chen Yuhan Liao Fan Zhou Chen Zhang Linlin Shao Jun Feng Tubao He Weihai Ning Yan Kong Yingqing Huo Aibin He Bing Liu Jingjing Zhang Ralf Adams Yulong He Fuchou Tang Xiuwu Bian Jincai Luo | 2020 | Cell Research2020，30，3： | 11 |
| 7 | Wwp2 mediates Oct4 ubiquitination and its own auto-ubiquitination in a dosage-dependent manner显示文摘抄写因素 Oct4 在维持 pluripotency 并且控制胚胎的干细胞(转换字符) 的系承诺起关键作用。我们的以前的学习显示那 Wwp2,鼠标 HECT 类型 E3 ubiquitin ligase, ubiquitinates Oct4 并且在一个 heterologous 系统支持它的降级。然而,在象 Wwp2 的功能的分子的特征一样调整内长的 Oct4 蛋白质层次的 Wwp2 的角色一直不是坚定的。这里,我们报导 Wwp2 在 embryonal 癌房间(ECC ) 的区别期间在 Oct4 ubiquitination 和降级起一个重要作用,尽管它不看起来在无差别的 ECC 和转换字符影响 Oct4 蛋白质层次。重要地,由特定的 RNA 干扰的 Wwp2 表示的抑制提高 Oct4 蛋白质水平,导致在 retinoid 的变细区别相关的标记基因的导致酸的激活。机械学地, Wwp2 经由离氨酸催化 Oct4 poly-ubiquitination 以一种剂量依赖者方式的 63 连接。有趣地, Wwp2 也以一种类似的方式调整它的自己的 ligase 活动。而且, Wwp2 的 auto-ubiquitination 通过 intra 分子的机制发生。一起拿,这些结果在在 ECC 的区别过程期间控制内长的 Oct4 蛋白质层次表明 Wwp2 的一个关键角色并且为调整 E3 ubiquitin ligase 的催化活动建议有趣的剂量依赖者机制, Wwp2。 | Bing Liao | 2010 | Cell Research2010，20，3： | 10 |
| 8 | Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells显示文摘RNase III DROSHA is upregulated in multiple cancers and contributes to tumor progression by hitherto unclear mechanisms.Here,we demonstrate that DROSHA interacts withβ-Catenin to transactivate STC1 in an RNA cleavage-independent manner,contributing to breast cancer stem-like cell(BCSC)properties.DROSHA mRNA stability is enhanced by N6-methyladenosine(m^(6)A)modification which is activated by AURKA in BCSCs.AURKA stabilizes METTL14 by inhibiting its ubiquitylation and degradation to promote DROSHA mRNA methylation.Moreover,binding of AURKA to DROSHA transcript further strengthens the binding of the m^(6)A reader IGF2BP2 to stabilize m^(6)A-modified DROSHA.In addition,wild-type DROSHA,but not an m^(6)A methylation-deficient mutant,enhances BCSC stemness maintenance,while inhibition of DROSHA m^(6)A modification attenuates BCSC traits.Our study unveils the AURKA-induced oncogenic m^(6)A modification as a key regulator of DROSHA in breast cancer and identifies a novel DROSHA transcriptional function in promoting the BCSC phenotype. | Fei Peng Jie Xu Bai Cui Qilan Liang Sai Zeng Bin He Hong Zou Manman Li Huan Zhao Yuting Meng Jin Chen Bing Liu Shasha Lv Peng Chu Fan An Zifeng Wang Junxiu Huang Yajing Zhan Yuwei Liao Jinxin Lu Lingzhi Xu Jin Zhang Zhaolin Su Zhiguang Li Fangjun Wang Eric W-FLam Quentin Liu | 2021 | Cell Research2021，31，3： | 9 |
| 9 | Study on chronic pancreatitis and pancreatic cancer using MRS and pancreatic juice samples显示文摘AIM:To investigate the markers of pancreatic diseases and provide basic data and experimental methods for the diagnosis of pancreatic diseases.METHODS:There were 15 patients in the present study,among whom 10 had pancreatic cancer and 5,chronic pancreatitis.In all patients,pancreatic cancer or chronic pancreatitis was located on the head of the p-a-ncrea-s.Pa-thology da-ta-of a-ll p-a-tients wa-s confirmed by biopsy and surgery.Among the 10 patients with pancreatic cancer,3 people had a medical history of longterm alcohol consumption.Of 5 patients with chronic pancreatitis,4 men suffered from alcoholic chronic pancreatitis.Pancreatic juice samples were obtained from patients by endoscopic retrograde cholangiopancreatography.Magnetic resonance spectroscopyn was performed on an 11.7-T scanner (Bruker DRX-500) using Call-Purcell-Meiboom-Gill pulse sequences.The parameters were as follows:spectral width,15 KHz;time domain,64 K;number of scans,512;and acquisition time,2.128 s.RESULTS:The main component of pancreatic juice included leucine,iso-leucine,valine,lactate,alanine,acetate,aspartate,lysine,glycine,threonine,tyrosine,histidine,tryptophan,and phenylalanine.On performing 1D 1H and 2D total correlation spectroscopy,we found a triplet peak at the chemical shift of 1.19 ppm,which only appeared in the spectra of pancreatic juice obtained from patients with alcoholic chronic pancreatitis.This triplet peak was considered the resonance of the methyl of ethoxy group,which may be associated with the metabolism of alcohol in the pancreas.CONCLUSION:The triplet peak,at the chemical shift of 1.19 ppm is likely to be the characteristic metabolite of alcoholic chronic pancreatitis. | Jian Wang Chao Ma Zhuan Liao Bing Tian Jian-Ping Lu | 2011 | World Journal of Gastroenterology2011，17，16： | 9 |
| 10 | Clinicopathological features and trend changes of gastric carcinoma in Southern China显示文摘AIM:To investigate the clinicopathological features of gastric carcinoma in southern China and disease trends changes over the last 18 years.METHODS:We designed a retrospective study in the Department of Gastrointestinal Surgery,the first affiliated hospital,Sun Yat-sen University.A total of 2100adult patients with definitely diagnosed,histologically proven gastric carcinomas treated with radical gastrectomy from 1994 to 2013 were examined retrospectively.In all cases patient age,gender,tumor location,Borrmann type,histopathological type and grade,and pTNM stage were identified and recorded.The information was obtained from hospital records.The data were analyzed with Stata12.0 software.RESULTS:In this study,the mean age of patients was 57 years with a range from 19-89 years.A higher incidence was found in patients over 60 years of age.In the study population,67.38%of patients were male and 32.62%were female.Women had a higher disease incidence than men in patients less than 40 years of age(P<0.001).No obvious change of patient age and gender was observed in the last 18 years.The rates of disease by location were the following:antrum(44.57%),followed by fundus/body(24.95%)and cardia/gastroesophageal junction(23.00%).The mean tumor diameter was 5.57 cm,and advanced gross type BorrmannⅢwas most common.Most patients were at advanced stages when first diagnosed,and patients with early stage disease were relatively rare.More early stage patients were detected in recent years,especially after 2000(P<0.001).Gastric carcinoma has different features in young and old patients.The young patients had the following features:more frequently female,tumors in the antrum,larger tumor size,poorly differentiated carcinoma,high rate of metastasis to other sites and advanced stages(P<0.05).CONCLUSION:In southern China,gastric carcinoma was more frequent in old men and young women.Young and old patients should be treated differently for having different features. | Jian-Jun Peng Ping Xiao Jian-Bo Xu Wu Song Bing Liao Yu-Long He | 2014 | World Journal of Gastroenterology2014，20，15： | 9 |
| 11 | Effect of RNA interference therapy on the mice eosinophils CCR3 gene and granule protein in the murine model of allergic rhinitis显示文摘Objective:To observe the clinical manifestations of allergic rhinitis mice and the expression changes of the eosinophils CCR3 and the granule protein rnRNA in the bone marrow,peripheral blood and nasal lavage fluid.Mctliods:Twenty-four BALB/c mice were randomly divided into the control group.PBS therapy group.siKNA therapy group and the CCR3 siRNA therapy group(n=6).Allergic rhinitis model were sensitized and stimulated by ovalbunfin,and CCR3 siKNA therapy group were administered with CCH3 transnasally before stimulated.The levels of the eosinophils CCR3.MBP.ECP and EPO in bone marrow,peripheral blood and nasal lavage fluid were detected by RT-PCR.Results:Compared to the control group and CCR3 siR.NA therapy group,the nasal mucosa of the PBS therapy group and siRNA therapy group developed epithalaxy.goblet cells hyperplasia,squamous epithelium metaplasia,epithelium necrosis,lamina propria and submucosa gland hyperplasia,vasodilatation,tissue edema,and the characterized eosinophil infiltration.RT-PCR indicated that the CCR3 rnRNA,MBP.ECP and EPC)expression in bone marrow,peripheral blood and nasal lavage fluid of the CCR3 siKNA therapy group was lower than the PBS therapy group and siR.NA therapy group(P<0.05).Conclusions:The RNA interference therapy to CCR3 by local administration pernasal can suppress the process of the development,migration and invasion of the allergic rhinitis eosinophil,thus can reduce the effect of eosinophils and then reduce the inflammation effect of the allergic rhinitis.It may be a new treatment for respiratory tract allergic inflammation. | Xin-Hua Zhu Bing Liao Ke Liu Yue-Hui Liu | 2014 | Asian Pacific Journal of Tropical Medicine2014，7，3： | 7 |
| 12 | Multiple effects of nitrate amendment on the transport, transformation and bioavailability of antimony in a paddy soil-rice plant system显示文摘Nitrate(NO3^(-))is known to be actively involved in the processes of mineralization and heavy metal transformation;however,it is unclear whether and how it affects the bioavailability of antimony(Sb)in paddy soils and subsequent Sb accumulation in rice.Here,the effects of NO3^(-)on Sb transformation in soil-rice system were investigated with pot experiments over the entire growth period.Results demonstrated that NO3^(-)reduced Sb accumulation in brown rice by 15.6%compared to that in the control.After amendment with NO3^(-),the Sb content in rice plants increased initially and then gradually decreased(in roots by 46.1%).During the first 15 days,the soil p H increased,the oxidation of Sb(Ⅲ)and sulfides was promoted,but the reduction of iron oxide minerals was inhibited,resulting in the release of adsorbed and organic-bound Sb from soil.The microbial arsenite-oxidizing marker gene aox B played an important role in Sb(Ⅲ)oxidation.From days 15 to 45,after NO3^(-)was partially consumed,the soil p H decreased,and the reductive dissolution of Fe(Ⅲ)-bearing minerals was enhanced;consequently,iron oxide-bound Sb was transformed into adsorbed and dissolved Sb species.After day 45,NO3^(-)was completely reduced,Sb(V)was evidently reduced to Sb(Ⅲ),and green rust was generated gradually.Thus,the available Sb decreased due to its enhanced affinity for iron oxides.Moreover,NO3^(-)inhibited the reductive dissolution of iron minerals,which ultimately caused low Sb availability.Therefore,NO3^(-)can chemically and biologically reduce the Sb availability in paddy soils and alleviate Sb accumulation inrice.This study provides a potential strategy for decreasing Sb accumulation in rice in the Sb-contaminated sites. | Xiaofeng Zhang Tongxu Liu Fangbai Li Xiaomin Li Yanhong Du Huanyun Yu Xiangqin Wang Chuanpin Liu MiFeng Bing Liao | 2021 | Journal of Environmental Sciences2021，33，2： | 6 |
| 13 | Removal of radioactive cesium from solutions by zinc ferrocyanide显示文摘Adsorption of ^(134)Cs from aqueous solution by zinc fcrrocyanide,and the effect of experimental conditions on the adsorption were investigated.Preliminary results showed that zinc ferrocyanide was very efficient as an absorbent.Over 98% of ^(134)Cs could be removed by zinc ferrocyanide of 0.33 g·L^(-1) from ^(134)Cs solution (Co) of 3.2~160.0 kBq·L^(-1),with adsorption capacities (Q) of 9.6~463.0 kBq·g^(-1).The adsorption equilibrium time was within one hour and the suitable pH ranged 1~10.No significant differences on ^(134)Cs adsorption were observed at 0~50℃,or in solutions containing Ca^(2+),Fe^(3+),Mg^(2+),HCO_3^-,CO_3^(2-),Cl and SO_4^(2-),even though they are 1000 times higher than the anions or cations in groundwater.However,the adsorption rates decreased when solutions contained K^+ or Na^+.The adsorption process could be described by Frcundlich and Langmuir adsorption equations. | LI Bing LIAO Jiali WU Jiaojiao ZHANG Dong ZHAO Jun YANG Yuanyou CHENG Qiong FENG Yue LIU Ning | 2008 | Nuclear Science and Techniques2008，19，2： | 5 |
| 14 | Tree of life for the genera of Chinese vascular plants显示文摘我们重建了使用的中国脉管的植物(Tracheophyta ) 的一棵种系发生的树叶绿体基因 atpB, matK, ndhF,和 rbcL 和 mitochondrial matR 定序。我们生产了包括 6098 种类并且包括 13 个 695 DNA 序列, 1803 最新被产生的一个矩阵。我们的分类采样跨越了代表中国脉管的植物的 323 个家庭的 3114 个类,盖住从中国知道的超过 93% 所有类。全面大发展史支持大多数关系在之中并且在最近的分子的种系发生的研究为 lycophytes,蕨纲植物(monilophytes ) ,裸子植物,和被子植物认出的家庭以内。为被子植物,在被子植物发展史组 IV 的大多数家庭作为 monophyletic 被养活,除了 paraphyletic Dipterocarpaceae 和 Santalaceae。一些大类的几个大家庭并且 monophyly 的 infrafamilial 关系被我们的稠密的分类采样很好支持。我们的结果证明 Eberhardtia 的二种是到 Sapotaceae 的所有另外的 taxa 形成的 clade 的姐妹,除了 Sarcosperma。我们经由 SoTree (http://gffzz52bf878016c04d01hnncocnwnp90n6kv0.ffgz.tsg.suse.edu.cn/flora/index.shtml ) 做了我们为子树的创造公开地可得到的中国脉管的植物的发展史,为生态学家的一个自动化发展史集会工具。 | Zhi-Duan Chen Tuo Yang Li Lin Li-Min Lu Hong-Lei Li Miao Sun Bing Liu Min Chen Yan-Ting Niu Jian-Fei Ye Zhi-Yong Cao Hong-Mei Liu Xiao-Ming Wang Wei Wang Jing-Bo Zhang Zhen Meng Wei Cao Jian-Hui Li Sheng-Dan Wu Hui-Ling Zhao Zhong-Jian Liu Zhi-Yuan Du Qing-Feng Wang Jing Guo Xin-Xin Tan Jun-Xia Su Lin-Jing Zhang Lei-Lei Yang Yi-Ying Liao Ming-He Li Guo-Qiang Zhang Shih-Wen Chung Jian Zhang Kun-Li Xiang Rui-qi Li Douglas E. Soltis Pamela S. Soltis Shi-Liang Zhou Jin-Hua Ran Xiao-quan Wang Xiao-Hua Jin You-Sheng Chen Tian-Gang Gao Jian-Hua Li Shou-Zhou Zhang An-Ming Lu China Phylogeny Consortium | 2016 | Journal of Systematics and Evolution2016，54，4： | 5 |
| 15 | Clinical and experimental study of therapeutic effect of Weixibaonizhuan pills on gastric precancerous lesions显示文摘ClinicalandexperimentalstudyoftherapeuticefectofWeixibaonizhuanpilsongastricprecancerouslesionsZHANGXuChen1,GAORuiFeng2,LI... | ZHANG XuChen1, GAO RuiFeng2, LI BingQing2, MA LianSheng3, MEI LiXin1, WU YuZhen2, LIU FengQin2 and Liao ZhengLin2 | 1998 | World Journal of Gastroenterology1998，4，1： | 5 |
| 16 | MATRIEX imaging:multiarea two-photon real-time in vivo explorer显示文摘Two-photon laser scanning microscopy has been extensively applied to study in vivo neuronal activity at cellular and subcellular resolutions in mammalian brains.However,the extent of such studies is typically confined to a single functional region of the brain.Here,we demonstrate a novel technique,termed the multiarea two-photon real-time in vivo explorer(MATRIEX),that allows the user to target multiple functional brain regions distributed within a zone of up to 12mm in diameter,each with a field of view(FOV)of ~200μm in diameter,thus performing two-photon Ca2+imaging with single-cell resolution in all of the regions simultaneously.For example,we demonstrate real-time functional imaging of single-neuron activities in the primary visual cortex,primary motor cortex and hippocampal CA1 region of mice in both anesthetized and awake states.A unique advantage of the MATRIEX technique is the configuration of multiple microscopic FOVs that are distributed in three-dimensional space over macroscopic distances(>1 mm)both laterally and axially but that are imaged by a single conventional laser scanning device.In particular,the MATRIEX technique can be effectively implemented as an add-on optical module for an existing conventional single-beam-scanning two-photon microscope without requiring any modification to the microscope itself.Thus,the MATRIEX technique can be readily applied to substantially facilitate the exploration of multiarea neuronal activity in vivo for studies of brain-wide neural circuit function with single-cell resolution. | Mengke Yang Zhenqiao Zhou Jianxiong Zhang Shanshan Jia Tong Li Jiangheng Guan Xiang Liao Bing Leng Jing Lyu Kuan Zhang Min Li Yan Gong Zhiming Zhu Junan Yan Yi Zhou Jian K Liu Zsuzsanna Varga Arthur Konnerth Yuguo Tang Jinsong Gao Xiaowei Chen Hongbo Jia | 2019 | Light(Science & Applications)2019，8，1： | 4 |
| 17 | Effect of montmorillonite on kinetics of polyurethane preparation reaction显示文摘prepolymerization 和 polyurethane/montmorillonite 的治好的反应动力学分别地与端基分析和 FTIR 被学习了。prepolymerization 和治好的反应跟随了第二顺序动力学,这被发现。但是在 montmorillonite 以后从 42.7 kJ/mol 增加到 56.5 kJ/mol 的 prepolymerization 的激活精力在治好反应的反应系统,和激活精力被增加从 64.4 kJ/mol 减少了到 17.5 kJ/mol。 | You Cao Yu Jiang Shu Lu Zhao Xiao Jun Cai Mei Long Hu Bing Liao | 2008 | Chinese Chemical Letters2008，19，1： | 4 |
| 18 | Electrospinning of hydroxypropyl methylcellulose trimellitate solutions显示文摘Nonwoven fiber mats of hydroxypropyl methylcellulose trimellitate(HPMCT) with potential applications in controlled delivery of drugs and scaffolds for tissue cultures have been successfully fabricated by electrospinning of HPMCT solutions.The formation and diameters of HPMCT fibers fabricated by electrospinning were strongly influenced by the solvents employed,electrostatic field strength,and solution concentrations.The electrospun products generated from all HPMCT solutions with various weight-average molecular weights in methanol/dichloromethane(1:1) solvent consisted of clustered beads,while methanol/dichloromethane(1:5) solvent helped to generate smooth,uniform,submicron fibers.From the relationship between specific viscosity and molecular weight in different solvents,it could be concluded that methanol/dichloromethane(1:5) solvent enhanced the molecular entanglements,improved the viscosity of the solutions,thus helped to generate smooth fibers.When all the other variables were kept constant,the concentration range suitable for electrospinning was between 10% and 16%(wt),and the average fiber diameter increased as the concentration increased.When all the other variables were kept constant,the average fiber diameter decreased as the strength of the electrostatic field increased.Electrospinning the solutions of two compounds with similar structure,hydroxypropyl methylcellulose phthalate(HPMCP) and HPMCT,we found that the fibers electrospun from HPMCP were thicker than that from HPMCT,which is attributed to the fact that the solution's conductivity of HPMCT(containing two free carboxyl groups) is higher than that of HPMCP(containing only one free carboxyl group). | MA Gang,SHAO ZiQiang,WANG WenJun,WANG FeiJun,TAN LingLing & LIAO Bing School of Material,Beijing Institute of Technology,Beijing 100081,China | 2010 | Science China Chemistry2010，53，1： | 3 |
| 19 | Interaction between uranium and humic acid (Ⅱ): complexation, precipitation and migration behavior of U(Ⅵ) in the presence of humic substances显示文摘The complexation, precipitation, and migration behavior of uranium in the presence of humic acid (HA) or fulvic acid (FA) were investigated by cation exchange, ultrafiltration and dynamic experiment, respectively. The results showed that (i) complex equilibrium between the uranium and humic substances was achieved at approximately 72 h, (ii) the coordination number varied from 1:1 to 1:2 ( U(Ⅵ) : humic acid) as pH increased from 3 to 6; and (iii) , while the complex stability constant decreased when temperature increased, but increased with pH value. We found that the precipitation of uranyl could only be observed in presence of HA, and the precipitation was influenced by conditions, such as pH, uranium concentration, temperature, and the HA concentration. The maximum precipitation proportion up to 60% could be achieved in the condition of 40 mg/L HA solution at pH 6. We further observed that the migration behavior of uranium in soil in the presence of humic acid (HA) or fulvic acid (FA) was different from that in the presence of inorganic colloid, and the effect of humic substances (HS) was limited. | LIAO Jiali WEN Wei LI Bing YANG Yuanyou ZHANG Dong KANG Houjun YANG Yong JIN Jiannan LIU Ning | 2013 | Nuclear Science and Techniques2013，24，3： | 3 |
| 20 | 5-Amino-4-oxopentanoic acid photodynamic diagnosis guided microsurgery and photodynamic therapy on VX2 brain tumour implanted in a rabbit model显示文摘背景完全的瘤切除术为改进大脑瘤病人的预后是重要的。然而,因为瘤边缘是困难的与包围大脑织物被区分开来,广泛的切除术仍然保持争论。它被建立了那 5-amino-4-oxopentanoic 酸(5-aminolevulinic 酸,翼) 能在大脑瘤的外科的治疗为光力学的治疗被用作一个光力学的诊断标记和 photosensitizer。我们调查了 VX2 大脑瘤上的 microsurgery 和光力学的治疗在与 VX2 大脑瘤植入的八十只新西兰兔子随机被分到五个组的兔子 model.Methods 植入的光力学地指导的翼的功效:在哪个指导了 microsurgery 的控制,常规白轻 microsurgery,一个光力学的治疗组,一个光力学地指导的 microsurgery 组和一个组被光力学的治疗跟随。VX2 瘤是在一台外科的显微镜下面的 resected。瘤切除术与组织学的分析被证实。所有动物为任何剩余瘤织物的存在与 MRI 被检验。每只兔子的幸存时间 group.Photodynamically 与控制相比是所有处理组显示出的 recorded.Results 一显著地扩大的幸存时间显著地与光力学的治疗相结合的指导 microsurgery 独自延长了幸存时间,与指导 microsurgery 相比。 MRI 和尸体结果证实了那个光力学地指导的手术和光力学的治疗显著地减少,增加激进的切除术的有效性并且延长瘤适用的幸存时间的我们的结果建议的 tumours.Conclusions 的大多数或延期本地人复发的移动兔子,他们的联合有潜力被用作变形大脑瘤的一个快速、高度有效的处理。 | XIAO Hong LIAO Qiong CHENG Ming LI Fei XIE Bing LI Mei FENG Hua | 2009 | Chinese Medical Journal2009，，11： | 3 |
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