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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | Effect of curcumin on multidrug resistance in resistant human gastric carcinoma cell line SGC7901/VCR显示文摘瞄准:调查杂种狗枯茗的颠倒效果在上多,在一个抵抗的人的胃的癌房间的药抵抗(MDR ) 排队。方法:长春新碱(VCR ) 的细胞毒素的效果被 MTT 试金评估。VCR 导致的房间 apoptosis 被染色的 propidium 碘化物(PI ) 决定流动血细胞计数(FCM ) 和用吖啶橙(AO ) 的词法试金 /ethidium 溴化物(EB ) 双染色。P-glycoprotein (P-gp ) 功能被 rhodamine123 (Rh123 ) 的累积和流出用 FCM 表明。P-gp 的表示和 caspase-3 的激活被 FCM 用结合的荧光黄异硫氰酸盐(FITC ) 测量 anti-P-gp 和劈开反的 caspase-3 抗体分别地。结果:在 5 micromol/L, 10 micromol/L,或 20 micromol/L 的集中,姜黄色素没在胃的癌房间线(SGC7901 ) 或它的 VCR 抵抗的变体房间衬里的一个父母人(SGC7901/VCR ) 上有细胞毒素的效果。SGC7901/VCR 房间的 VCR-IC50 价值是多于 SGC7901cells 的 45 次, SGC7901/VCR 房间显示出 apoptotic 抵抗到 VCR。与 5 micromol/L, 10 micromol/L,或 20 micromol/L 杂种狗枯茗对待的 SGC7901/VCR 房间减少了以一种剂量依赖者方式的 VCR 和支持的调停 VCR 的 apoptosis 的 IC50 价值。姜黄色素(10 micromol/L ) 增加了 Rh123 累积并且在 SGC7901/VCR 房间禁止了 Rh123 的流出,但是没在 SGC7901 房间改变 Rh123 的累积和流出。P-gp 完了在 SGC7901/VCR 表示了房间,而它低与杂种狗枯茗(10 micromol/L ) 在一个 24-h 处理以后调整了。独自与 1 mumol/L VCR 对待的抵抗房间在 44% 增加的抵抗房间线相对 caspase-3 的 SGC7901 房间,而是激活看了 caspase-3 激活的 77% 底层房间什么时候与杂种狗枯茗在联合与 VCR 被对待。结论:姜黄色素能颠倒人的胃的癌 SGC7901/VCR 房间线的 MDR。这可能与减少的 P-gp 被联系函数和表达式,和在 MDR 房间的 caspase-3 激活的提升。 | Xiao-qing TANG Hu BI Jian-qiang FENG Jian-guo CAO | 2005 | Acta Pharmacologica Sinica2005，26，8： | 49 |
| 3 | Identification and expansion of cancer stem cells in tumor tissues and peripheral blood derived from gastric adenocarcinoma patients显示文摘胃的癌症是世界范围的第四很普通的癌症,与死亡的高率和低 5 年的幸存率。迄今为止,有为胃的癌症的有效治疗学的协议的缺乏。最近的研究建议癌症干细胞(CSC ) 为肿瘤开始,侵略,转移,和抵抗负责到 anticancer 治疗。因此,指向胃的 CSC 的治疗是吸引人的。然而,在人的胃的腺癌(GAC ) 的 CSC 没被描述。这里,我们从 GAC 病人在肿瘤纸巾和外部血识别 CSC。从肿瘤纸巾和病人的外部血被孤立的人的 GAC (GCSC ) 的 CSC 带了 CD44 和 CD54 表面标记,当注入了 immunodeficient 老鼠时,高度类似于原来的人的肿瘤的产生肿瘤,在 vitro 区分了进胃的上皮的房间,并且在 vivo 并且在 vitro 自我更新。我们的调查结果建议有效治疗学的协议必须指向 GCSC。从 GAC 病人的循环的 GCSC 的俘获也为为肿瘤转移潜在地负责的一张批评房间人口的鉴定显示出大潜力,并且为早诊断并且胃的癌症的纵的监视提供一个有效协议。 | Tie Chen Kun Yang Jianhua Yu Wentong Meng Dandan Yuan Feng Bi Fang Liu Jie Liu Bing Dai Xinzu Chen Fang Wang Fan Zeng Hong Xu Jiankun Hu Xianming Mo | 2012 | Cell Research2012，22，1： | 50 |
| 4 | Chitosan conduits combined with nerve growth factor microspheres repair facial nerve defects显示文摘Microspheres containing nerve growth factor for sustained release were prepared by a compound method,and implanted into chitosan conduits to repair 10-mm defects on the right buccal branches of the facial nerve in rabbits.In addition,chitosan conduits combined with nerve growth factor or normal saline,as well as autologous nerve,were used as controls.At 90 days post-surgery,the muscular atrophy on the right upper lip was more evident in the nerve growth factor and normal saline groups than in the nerve growth factor-microspheres and autologous nerve groups.Electrophysiological analysis revealed that the nerve conduction velocity and amplitude were significantly higher in the nerve growth factor-microspheres and autologous nerve groups than in the nerve growth factor and normal saline groups.Moreover,histological observation illustrated that the diameter,number,alignment and myelin sheath thickness of myelinated nerves derived from rabbits were higher in the nerve growth factor-microspheres and autologous nerve groups than in the nerve growth factor and normal saline groups.These findings indicate that chitosan nerve conduits combined with microspheres for sustained release of nerve growth factor can significantly improve facial nerve defect repair in rabbits. | Huawei Liu Weisheng Wen Min Hu Wenting Bi Lijie Chen Sanxia Liu Peng Chen Xinying Tan | 2013 | Neural Regeneration Research2013，8，33： | 22 |
| 5 | The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals显示文摘Metabolic diseases are the most common and rapidly growing health issues worldwide.The massive population-based human genetics is crucial for the precise prevention and intervention of metabolic disorders.The China Metabolic Analytics Project(ChinaMAP)is based on cohort studies across diverse regions and ethnic groups with metabolic phenotypic data in China.Here,we describe the centralized analysis of the deep whole genome sequencing data and the genetic bases of metabolic traits in 10,588 individuals from the ChinaMAP.The frequency spectrum of variants,population structure,pathogenic variants and novel genomic characteristics were analyzed.The individual genetic evaluations of Mendelian diseases,nutrition and drug metabolism,and traits of blood glucose and BMI were integrated.Our study establishes a large-scale and deep resource for the genetics of East Asians and provides opportunities for novel genetic discoveries of metabolic characteristics and disorders. | Yanan Cao Lin Li Min Xu Zhimin Feng Xiaohui Sun Jieli Lu Yu Xu Peina Du Tiange Wang Ruying Hu Zhen Ye Lixin Shi Xulei Tang Li Yan Zhengnan Gao Gang Chen Yinfei Zhang Lulu Chen Guang Ning Yufang Bi Weiqing Wang The ChinaMAP Consortium | 2020 | Cell Research2020，30，9： | 20 |
| 6 | Changes in visibility with PM_(2.5) composition and relative humidity at a background site in the Pearl River Delta region显示文摘In fall–winter, 2007–2013, visibility and light scattering coefficients(b sp) were measured along with PM_(2.5)mass concentrations and chemical compositions at a background site in the Pearl River Delta(PRD) region. The daily average visibility increased significantly(p < 0.01) at a rate of 1.1 km/year, yet its median stabilized at ~13 km. No haze days occurred when the 24-hr mean PM_(2.5)mass concentration was below 75 μg/m^3. By multiple linear regression on the chemical budget of particle scattering coefficient(b sp), we obtained site-specific mass scattering efficiency(MSE) values of 6.5 ± 0.2, 2.6 ± 0.3, 2.4 ± 0.7 and 7.3 ± 1.2 m2/g,respectively, for organic matter(OM), ammonium sulfate(AS), ammonium nitrate(AN) and sea salt(SS). The reconstructed light extinction coefficient(b ext) based on the Interagency Monitoring of Protected Visual Environments(IMPROVE) algorithm with our site-specific MSE revealed that OM, AS, AN, SS and light-absorbing carbon(LAC) on average contributed 45.9% ± 1.6%,25.6% ± 1.2%, 12.0% ± 0.7%, 11.2% ± 0.9% and 5.4% ± 0.3% to light extinction, respectively.Averaged b ext displayed a significant reduction rate of 14.1/Mm·year(p < 0.05); this rate would be 82% higher if it were not counteracted by increasing relative humidity(RH) and hygroscopic growth factor(f(RH)) at rates of 2.5% and 0.16/year-1(p < 0.01), respectively, during the fall–winter, 2007–2013. This growth of RH and f(RH) partly offsets the positive effects of lowered AS in improving visibility, and aggravated the negative effects of increasing AN to impair visibility. | Xiaoxin Fu Xinming Wang Qihou Hu Guanghui Li Xiang Ding Yanli Zhang Quanfu He Tengyu Liu Zhou Zhang Qingqing Yu Ruqing Shen Xinhui Bi | 2016 | Journal of Environmental Sciences2016，28，2： | 18 |
| 7 | Characteristics of rare-earth elements (REE),strontium and neodymium isotopes in hydrothermal fluorites from the Bailashui tin deposit in the Furong ore field,southern Hunan Province,China显示文摘In this paper the authors present the REE concentrations and Sr and Nd isotopic compositions of fluorites from the Bailashui tin deposit of the Furong ore field,southern Hunan Province. The results showed that the total amount of REE in fluorites is usually low,ranging from 0.705 to 8.785 μg/g with the chondrite-normalized REE dis-tribution patterns similar to those of the Qitianling granites in the study area,characterized by LREE-enrichment patterns with pronounced negative Eu anomalies. The fluorites vary in Sr isotopic composition within the range of 0.7083-0.7091,the values are lower than those of the granites and higher than those of the host carbonate rocks in this area. The εNd(t) values of fluorites vary between -9.4 and +10.3,revealing that both the crust-and mantle-source materials were involved in the ore-forming hydrothermal fluids. Combined with previous studies on this ore deposit,the Bailashui tin deposit is temporally and spatially closely related with granitic magmatism in this area. The hydro-thermal fluorites are the product of fluid/rock interactions between granitic magmatic hydrothermal fluid and marine carbonate rocks. The REE and F in the ore-forming fluid were derived from the granites,whereas Sr in the ore-forming fluid came mainly from the granitic magmatic hydrothermal fluid and marine carbonate rocks,although variations in Sr isotopic composition cannot be explained by a simple mixture of these two end-members. Evidence demonstrated that the ore-forming fluids are of crustal-mantle mixing origin,but that the fluids were probably in-completely homogenized and this may be caused by inhomogeneous mixing of the fluids of different sources. | YUAN Shunda PENG Jiantang HU Ruizhong BI Xianwu QI Liang LI Zhaoli LI Xiaomin SHUANG Yan | 2008 | Chinese Journal Of Geochemistry2008，27，4： | 16 |
| 8 | Preservation of the continence function after intersphincteric resection using a prolapsing technique in the patients with low rectal cancer and its clinical prognosis显示文摘肿瘤的 intersphincteric 切除术的技术与 coloanal 吻合相结合的背景被用来为病人避免永久结肠开口术,直肠的癌症定位了 < 从肛门边缘的 5 厘米。针对用 prolapsing technique.Methods 在 intersphincteric 切除术以后与更低的直肠的癌症估计剩余直肠和病人的临床的预后的克制功能的保藏的这研究这研究与下列包括标准包括了病人:(1 ) 在远侧的边缘以内的直肠的癌症和肿瘤的病理学的证据由外科手术前的内视镜的检查从肛门定位了 5 厘米或更少;(2 ) 不由也的渗入的 MRI 证实外部括约肌, puborectalis 或提肌肌肉;(3 ) 病人与与 well-to-moderate 区别显示出肿瘤的外科手术前的活体检视为 intersphincteric 切除术和更低的 coloanal 吻合是合格的。从 2000 年 1 月,到 6 月 2004,23 日,有低直肠的癌症的病人在这研究被包括。我们使用了标准 abdominoperineal 途径与内部括约肌的 mesorectum 和总数或部分的切除执行肿瘤的激进的切除术。病人为对剩余直肠的功能的评价被跟随,在 operations.Results 以后的癌症复发,从肛门边缘的中部的肿瘤距离是 4.5 (范围 3.5-5.0 ) 厘米和吝啬的远侧的外科的边缘 1.6 (范围 1.0-2.0 ) 厘米。癌症被分类进舞台我(30.4%) ,舞台(47.8%) ,和舞台(21.7%) 根据 TNM 分类。在外科的切除术和 2 个病人(8.7%) 在 coloanal 吻合的地点开发了 anastomotic 苛评的以后的阶段以后,二个病人开发了 anastomotic 管。中部的后续时期是 31.5 个月(范围 12-54 ) , 2 个病人(8.7%) 开发了本地复发。三死亡与远侧的机关转移被联系。二十个病人(87.0%) 维持了胜任在外科以后控制固体或液体凳子和屁克制的能力。在这些病人之中, 2 个病人能控制稳固的凳子并且偶尔失去液体凳子的克制。并且仅仅 1 个病人(4.4%) 在手术以后与稳固的凳子然而并非液体的好克制保留了部分直肠功能。在外科是 13.1,4.7,3.1,2.9,和 3.2 时间 / 天以后,每 3, 6, 12, 24 和 36 个月的天平均澄清的时间。在 intersphincteric 切除术和这个变化在后续的时期期间留下了以后,肛门压力计大小在休息时间期间显示出压力的减少。最大值挤压压力在外科以后在起始的减少以后被改进。在外科以后的更多的剩余直肠功能可以被低直肠癌症的 intersphincteric 切除术保存的结论。同时这种技术在外科以后与很少手术后的复杂并发症和低肿瘤复发是安全的。 | DAI Yong JIANG Jin-bo BI Dong-song JIN Zu-tao SUN Jing-zhong HU San-yuan | 2008 | Chinese Medical Journal2008，，20： | 16 |
| 9 | The HuangZaoSi Maize Genome Provides Insights into Genomic Variation and Improvement History of Maize显示文摘Maize is a globally important crop that was a classic model plant for genetic studies. Here, we report a 2.2 Gb draft genome sequence of an elite maize line, HuangZaoSi (HZS). Hybrids bred from HZS-improved lines (HILs) are planted in more than 60% of maize fields in China. Proteome clustering of six completed sequeneed maize genomes show that 638 proteins fall into 264 HZS-specific gene families with the majority of contributions from tandem duplication events. Resequencing and comparative analysis of 40 HZSrelated lines reveals the breeding history of HILs. More than 60% of identified selective sweeps were clustered in identity.by.descent conserved regions, and yield-related genes/QTLs were enriched in HZS characteristic selected regions. Furthermore, we dem on strated that HZS-specific family genes were not uniformly distributed in the genome but enriched in improvement/function.related genomic regions. This study provides an important and novel resource for maize genome research and expands our knowledge on the breadth of genomic variation and improvement history of maize. | Chunhui Li Wei Song Yingfeng Luo Shenghan Gao Ruyang Zhang Zi Shi Xiaqing Wang Ronghuan Wang Fengge Wang Jidong Wang Yanxin Zhao Aiguo Su Shuai Wang Xin Li Meijie Luo Shuaishuai Wang Yunxia Zhang Jianrong Ge Xinyu Tan Ye Yuan Xiaochun Bi Hang He Jianbing Yan Yuandong Wang Songnian Hu Jiuran Zhao | 2019 | Molecular Plant2019，12，3： | 15 |
| 10 | Effect of BN52021 on NFκ-Bp65 expression in pancreatic tissues of rats with severe acute pancreatitis显示文摘AIM: To investigate dynamic changes and significance of expression of NF-κBp65 in pancreatic tissues of rats with severe acute pancreatitis (SAP), as well as BN52021 effects. METHODS: Wistar male rats were randomly divided into negative control group (NC group, n = 60), SAP-model group (SAP group, n = 60), and BN52021-treated group (BN group, n = 60), and each of the above groups was respectively divided into 6 subgroups at different time points after operation (1 h, 2 h, 3 h, 6 h, 12 h, and 24 h) (n = 10). By RT-PCR and Western blot, NF-κBp65 mRNA and its protein expression in pancreatic tissues of rats were detected respectively. RESULTS: The expression of NF-κBp65 mRNA dynamically changed in both SAP groups and BN groups. The mRNA level was higher in SAP groups than NC groups at 2 h, 3 h, 12 h, and 24 h after operation (P < 0.05), higher in BN groups than NC groups at all time points (P < 0.05), and higher in BN groups than SAP group at 1 h (P < 0.05). The NF-κBp65 protein level was higher in SAP groups than NC groups at 1 h, 3 h, and 6 h (P < 0.01), and 2 h, 12 h, and 24 h (P < 0.05), higher in BN groups than NC groups at all time points (P < 0.05), and lower in BN groups than SAP groups at 1 h, 3 h, and 6 h (P < 0.05). CONCLUSION: The expression of NF-κBp65 in pancreatic tissues is dynamically changed and the changes play an important role in pathogenesis of SAP. BN52021 exerts therapeutic effects through reducing the expression level of NF-κBp65 protein in the early stage of SAP. | Shi-Hai Xia Dian-Chun Fang Chun-Xiu Hu Hui-Ying Bi Yin-Zhi Yang Yao Di | 2007 | World Journal of Gastroenterology2007，13，6： | 13 |
| 11 | VIBRATION CHARACTERISTICS OF FLUID-STRUCTURE INTERACTION OF CONICAL SPIRAL TUBE BUNDLE显示文摘Heat transfer enhancement is achieved by flow-induced vibration in elastic tube bundles heat exchangers.For a further understanding of heat transfer enhancement mechanism and tube structure optimization,it is of importance to study the vibration characteristics of fluid-structure interaction of tube bundles.The finite element method is applied in the study of fluid-structure interaction of a new type elastic heat transfer element,i.e.,the dimensional conical spiral tube bundle.The vibration equation and element matrix for the tube are set up by the regulation of different helical angles and coordinate transformation,together with the simplification of the joint body of the two pipes.The vibration characteristics of conical spiral tube bundle are analyzed at different velocities of the tube-side flow,and the critical velocity of vibration buckling is obtained.The results show that the natural frequency of the tube bundle decreases as the flow speed increases,especially for the first order frequency,and the critical velocity of vibration buckling is between 1.2665 m/s-1.2669 m/s.The vibration mode of conical spiral tube bundle is mainly z-axial,which is feasible to be induced and controlled. | YAN Ke GE Pei-qi BI Wen-bo SU Yan-cai HU Rui-rong | 2010 | Journal of Hydrodynamics2010，22，1： | 13 |
| 12 | Clinical characteristics and effectiveness of antiviral agents in hospitalized children with infectious mononucleosis in China:A multicenter retrospective study显示文摘Importance:The clinical characteristics of infectious mononucleosis(IM)in Chinese children have not been evaluated in multicenter studies,and the effectiveness of antiviral treatment are controversial.Objective:To investigate the clinical characteristics of Chinese children with IM and current status of antiviral therapy for affected patients.Methods:Hospitalized patients with IM were enrolled between 2018 and 2020 in five children’s hospitals in China.The clinical characteristics were compared among four age groups:<3 years,3-<6 years,6-<10 years,and≥10 years.The clinical characteristics of IM and effectiveness of antiviral therapy were compared among patients receiving acyclovir(ACV),ganciclovir(GCV),and no antiviral therapy(i.e.,non-antiviral group).Results:In total,499 patients were analyzed;most patients were 3-<6 years of age.The most common symptoms and signs included fever(100%),lymphadenopathy(98.6%),pharyngitis(86.4%),eyelid edema(76.8%),and snoring(72.9%).There were significant differences in rash,hepatomegaly,and liver dysfunction among the four age groups.Patients aged<3 years had a lower incidence of liver dysfunction and a higher incidence of rash.Among the 499 patients,50.1%were treated with GCV,26.3%were treated with ACV,and 23.6%received no antiviral therapy.Compared with the non-antiviral group,patients in the ACV and GCV groups had longer durations of fever(P<0.001).There were no significant differences in the incidences of complications among the three treatment groups.Interpretation:The incidence of IM in Chinese children peaked at 3-<6 years of age.Clinical features of IM varied according to age.Patients receiving antiviral therapy exhibited more serious clinical manifestations than did patients without antiviral therapy.The effectiveness of antiviral therapy for IM requires further analysis. | Huili Hu Huiling Deng Jing Bi Yi Xu Shuangjie Li Yue Xie Xinrong Sun Dongmeng Wang Xufang Li Wenxian Ouyang Bing Hu Yufeng Zhang He Tang Chunxiao Fang Hui Zhang Lingyun Guo Chen Wang Tianyi Wang Fengxia Yang Tao Jiang Zhengde Xie Gang Liu | 2021 | Pediatric Investigation2021，5，3： | 12 |
| 13 | Chromosomal localization of the major ribosomal RNA genes in scallop Chlamys farreri显示文摘The chromosomes of Chlamys farreri were analyzed by means of silver staining and fluorescence in situ hybridization (FISH) with 18S—28S rDNA probe. Probe was made by PCR amplification of a DNA fragment containing internal transcribed spacers ITS1 between 18S and 5.8S ribosomal RNA gene, ITS2 between 5.8S and 28S ribosomal RNA gene and 5.8S rRNA gene, and labeled by PCR incorporation of bio-16-dUTP. FISH signals were located on the short arm of subtelocentric chromosome 10. After silver-staining, nucleolus organizer regions (NORs) could be observed on the telomere of the short arm of chromosome 10. However, one metaphase spread displayed an additional silver spot on the short arm of subtelocentric chromosome 12. | HUANG Xiaoting BAO Zhenmin BI Ke HU Jingjie ZHANG Can ZHANG Quanqi HU Xiaoli | 2006 | Acta Oceanologica Sinica2006，25，3： | 10 |
| 14 | Layered double hydroxides with atomic-scale defects for superior electrocatalysis显示文摘原子作文调节和缺点工程是有效策略 toenhance 由 improvingthe 的 multicomponent 催化剂的催化表演合作效果;然而,戏剧性地通过同时的缺点 engineeringat 在 multicomponent 材料上调节活跃地点仍然保持挑战性原子规模因为本地环境的类似。此处,把氧进化反应(OER ) 用作探查反应,我们 deliberatelyintroduced 底可溶的 Zn (II ) 或艾尔(III ) 地点进 NiFe 分层的双氢氧化物(LDH ) ,它是最好的 OER 催化剂之一。然后, Zn (II ) 或 siteswere 有选择地蚀刻创造原子 M (II ) 的艾尔(III )/M (III ) 背叛,哪个 dramaticallyenhanced OER 活动。在 20 妈的当前的密度?? | Oixian Xie Zhao Cai Pengsong Li Daojin Zhou Yongmin Bi Xuya Xiong Enyuan Hu Yaping Li Yun Kuang Xiaoming Sun | 2018 | Nano Research2018，11，9： | 8 |
| 15 | REE geochemical characteristics of the No. 302 uranium deposit in northern Guangdong, South China显示文摘The No. 302 uranium deposit, located in Guangdong Province, is a typical granite-type uranium ore deposit. REE geochemical characteristics of the wall rocks, pitchblende, altered rocks, calcite and fluorite from this deposit have been systematically studied in this paper. The result showed that the alkali-metasomatic granites and other altered rocks have the same REE distribution patterns as Indosinian granites. It is indicated that the hydrothermal ore-forming solution had altered the Indosinian granites, and ore-forming materials may directly originate from the Indosinian granites. Calcite and fluorite of different stages are the products derived from the same source but different stages. The evolution and degassing of the mineralizing solution might induce LREE enrichment to varying degree. Mantle fluid and a large volume of mineralizer may be the crucial factors controlling uranium mineralization, and the hydrothermal solution with mineralizer played an important role in U transport and concentration. Meanwhile, the degassing of CO2 might promote U and REE precipitation. | ZHANG Guoquan HU Ruizhong BI Xianwu FENG Haisheng SHANG Pengqiang TIAN Jianji | 2007 | Chinese Journal Of Geochemistry2007，26，4： | 8 |
| 16 | Genetic variation of Laminaria japonica (Phaeophyta) populations in China as revealed by RAPD markers显示文摘For the population genetics analysis of the naturally grown brown seaweed Laminaria japonica (Laminariales,Phaeophyta) sampled from Dalian,Yantai,Weihai,Rongcheng and Qingdao in China,ten primers were employed to produce 88 bands as revealed by randomly amplified polymorphic DNA (RAPD) markers,and all these bands were polymorphic.According to these band patterns,there were 94 distinct phenotypes occurred in 100 samples indicating the high heterozygosity of this kelp.Dalian population samples showed the highest percentage of polymorphism (71.67%),and also the higher diversity estimated on the basis of the Shannon’s index (8.498),suggesting that this population could be chosen as the best resource for genetic breeding.The highest diversity of Yantai population possibly resulted from the introduction of L.longissima used for interspecific cross breeding with L.japonica cultivated in China.From Dalian southwards to Qingdao,the genetic variation of the five populations became less with a decrease in latitude,possibly due to the natural selection especially of high temperature.The genetic distance (Φ ST values) of the five populations was a little significantly correlated with the geographical distance (r=0.496) at P =0.05 by Mantel’s test.Weihai,Rongcheng and Yantai populations were closely grouped genetically together by Neighbor-joining cluster analysis probably in that the dispersal of the kelp by propagules more easily occurring in the range of relatively short distance.The analysis of molecular variance (AMOVA) also demonstrated that the relatively higher variation occurred among populations (71.49%) at an extremely significant level (P <0.000 1).All these evidence showed that there was a relatively distinct genetic differentiation among the sampled kelp populations,and L.japonica grown in China was also rather heterozygous in heredity. | BI Yanhui HU Yuanjie ZHOU Zhigang | 2011 | Acta Oceanologica Sinica2011，30，2： | 7 |
| 17 | Metallic mesocrystal nanosheets of vanadium nitride for high-performance all-solid-state pseudocapacitors显示文摘转变金属氮化物(TMN ) 具有由他们优异电的电导率,优秀环境耐久性和高反应选择的协作优点的优点的特别兴趣,还完成灵活设计和操作是困难的。此处,钒氮化物(VN ) 的 mesocrystal nanosheets (MCNS ) 从热地稳定的分层的钒铜经由一条范围生长线路被综合,代表第一二维(2D ) 在无机的混合物的金属性的 mesocrystal。从他们的 single-crystalline-like 有益于远程的电子连接, VN MCNS 交付 1.44 的电的传导性 ??? 汰獵瀭畬 ?? ￣吗? | Wentuan Bi Zhenpeng Hu Xiaogang Li Changzheng Wu Junchi Wu Yi Xie | 2015 | Nano Research2015，8，1： | 7 |
| 18 | OpenKG Chain:A Blockchain Infrastructure for Open Knowledge Graphs显示文摘The early concept of knowledge graph originates from the idea of the semantic Web,which aims at using structured graphs to model the knowledge of the world and record the relationships that exist between things.Currently publishing knowledge bases as open data on the Web has gained significant attention.In China,Chinese Information Processing Society of China(CIPS)launched the OpenKG in 2015 to foster the development of Chinese Open Knowledge Graphs.Unlike existing open knowledge-based programs,OpenKG chain is envisioned as a blockchain-based open knowledge infrastructure.This article introduces the first attempt at the implementation of sharing knowledge graphs on OpenKG chain,a blockchain-based trust network.We have completed the test of the underlying blockchain platform,and the on-chain test of OpenKG’s data set and tool set sharing as well as fine-grained knowledge crowdsourcing at the triple level.We have also proposed novel definitions:K-Point and OpenKG Token,which can be considered to be a measurement of knowledge value and user value.1,033 knowledge contributors have been involved in two months of testing on the blockchain,and the cumulative number of on-chain recordings triggered by real knowledge consumers has reached 550,000 with an average daily peak value of more than 10,000.For the first time,we have tested and realized on-chain sharing of knowledge at entity/triple granularity level.At present,all operations on the data sets and tool sets at OpenKG.CN,as well as the triplets at OpenBase,are recorded on the chain,and corresponding value will also be generated and assigned in a trusted mode.Via this effort,OpenKG chain looks forward to providing a more credible and traceable knowledge-sharing platform for the knowledge graph community. | Huajun Chen Ning Hu Guilin Qi Haofen Wang Zhen Bi Jie Li Fan Yang | 2021 | Data Intelligence2021，3，2： | 7 |
| 19 | Boron modulating electronic structure of FeN4C to initiate high-efficiency oxygen reduction reaction and high-performance zinc-air battery显示文摘The biggest challenge is to develop a low cost and readily available catalyst to replace expensive commercial Pt/C for efficient electrochemical oxygen reduction reaction(ORR).In this research,closo-[B_(12)H_(12)]^(2−)and 1,10-phenanthroline-iron complexes were introduced into the porous metal-organic framework by impregnation method,and further annealing treatment achieved the successful anchoring of single-atom-Fe in B-doped CN Matrix(FeN4CB).The ORR activity of FeN4CB is comparable to the widely used commercial 20 wt%Pt/C.Where the half-wave potential(E_(1/2))in alkaline medium up to 0.84 V,and even in the face of challenging ORR in acidic medium,the E_(1/2)of ORR driven by FeN4CB is still as high as 0.81 V.When FeN4CB was used as air cathode,the open circuit voltage of Zn-air battery reaches 1.435 V,and the power density and specific capacity are as high as 177 mW cm^(−2)and 800 mAh g_(Zn)^(−1)(theoretical value:820 mAh g_(Zn)^(−1)),respectively.The dazzling point of FeN4CB also appears in the high ORR stability,whether in alkaline or acidic media,E_(1/2)and limiting current density are still close to the initial value after 5000 times cycles.After continuously running the charge-discharge test for 220 h,the charge voltage and discharge voltage of the rechargeable zinc-air battery with FeN4CB as the air cathode maintained the initial state.Density functional theory calculations reveals that introducing B atom to Fe–N4–C can adjust the electronic structure to easily break O=O bond and significantly reduce the energy barrier of the rate-determining step resulting in an improved ORR activity. | Xue Zhao Xue Li Zenghui Bi Yuwen Wang Haibo Zhang Xiaohai Zhou Quan Wang Yingtang Zhou Huaisheng Wang Guangzhi Hu | 2022 | Journal of Energy Chemistry2022，31，3： | 6 |
| 20 | Ge-rich hydrothermal solutions and abnormal enrichment of Ge in coal显示文摘AT present, the main source of germanium includes two types of ore deposits: some sulfide-rich Pb, Zn,Cu, Ag and An deposits and some coal deposits. Germanium occurs as an associated element in these oredeposits. The Lincang germanium deposit discovered recently in China occurs in a basin where there areexposed the Neogene coal-bearing clastic rocks with Indosinian Ge-rich ((1.9-5.0)×10-6) granitesas the basement in Lincang County, Yunnan Province. Germanium is mainly concentrated in the coalseams of the first coal-bearing horizon (Nth2) and in regard to its grade (normally n×100×10-6 with themaximum over 1000×10-6) and scale (the proven reserve about 800 t), no such germanium mineralization has been reported so far in other parts of the world. What is the reason? The available studies have indicated that this germanium deposit is of epigenetic origin, whichdetermines that germanium must have been transferred into coal with the help of a kind of medium. It isnoticed that (i) organic germanium in natural waters is stable and it is never involved in its | HU Ruizhong, BI Xianwu, SU Wenchao, QI Huawen and YE Zaojun Intitue of Geochemistry, Chinese Academy of Sciences, Guiyang 550002, China | 1999 | Chinese Science Bulletin1999，44，S2： | 5 |
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