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| 1 | High expression of trimethylated histone H3 lysine 4 is associated with poor prognosis in hepatocellular carcinoma显示文摘 | Chuanchao He Junyao Xu Jianlong Zhang Dan Xie Hua Ye Zhiyu Xiao Muyan Cai Kang Xu Yunjie Zeng Haigang Li Jie Wang | 2012 | Human Pathology2012，，9： | 3 |
| 2 | Use of Network Pharmacology and Molecular Docking to Investigate the Mechanism by Which Ginseng Ameliorates Hypoxia显示文摘Hypoxia is a common pathological process in various clinical diseases and is characterized by abnormal changes in metabolism,function,and morphological structure of tissues resulting from insufficient oxygen supply or oxygen barriers in tissues.In particular,hypoxia in vital organs such as the brain and heart is an important cause of death[1].The prevention of tissue hypoxia and the treatment of hypoxia-induced tissue damage are urgent issues. | WANG Tao LI Hao Tian WEI Shi Zhang CAI Hua Dan ZHU Yun LIU Hong Hong LI Yong Zhi WANG Jia Ping ZOU Wen Jun ZHAO Yan Ling | 2018 | Biomedical and Environmental Sciences2018，31，11： | 2 |
| 3 | Kinetic Characteristics of Neutralizing Antibody Responses Vary among Patients with COVID-19显示文摘Objective The coronavirus disease 2019(COVID-19) pandemic continues to present a major challenge to public health. Vaccine development requires an understanding of the kinetics of neutralizing antibody(NAb) responses to severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).Methods In total, 605 serum samples from 125 COVID-19 patients(from January 1 to March 14, 2020)varying in age, sex, severity of symptoms, and presence of underlying diseases were collected, and antibody titers were measured using a micro-neutralization assay with wild-type SARS-CoV-2.Results NAbs were detectable approximately 10 days post-onset(dpo) of symptoms and peaked at approximately 20 dpo. The NAb levels were slightly higher in young males and severe cases, while no significant difference was observed for the other classifications. In follow-up cases, the NAb titer had increased or stabilized in 18 cases, whereas it had decreased in 26 cases, and in one case NAbs were undetectable at the end of our observation. Although a decreasing trend in NAb titer was observed in many cases, the NAb level was generally still protective.Conclusion We demonstrated that NAb levels vary among all categories of COVID-19 patients. Longterm studies are needed to determine the longevity and protective efficiency of NAbs induced by SARS-CoV-2. | LI Ling Hua TU Hong Wei LIANG Dan WEN Chun Yan LI An An LIN Wei Yin HU Ke Qi HONG Wen Shan LI Yue Ping SU Juan ZHAO San Tao LI Wei YUAN Run Yu ZHOU Ping Ping HU Feng Yu TANG Xiao Ping KE Chang Wen KE Bi Xia CAI Wei Ping | 2021 | Biomedical and Environmental Sciences2021，34，12： | 1 |
| 4 | Optimization of Mixed-Cultivation Conditions of Methanotrophs from the Aged Refuse显示文摘 | Mei Juan Zhao You Cai Su Qun Han Dan Huang Ren Hua Chen Hao Quan | 2012 | Advanced Materials Research2012，，433： | 1 |
| 5 | 'high risk' Key points of laparoseopic cholecystectomy for patients with gallbladder stones显示文摘 | Huang Hui against Dan Hua Cai Zhifang | 2014 | a report of 115 c Journal of clinical and biliary diseases2014，50，12： | 1 |
| 6 | Combination of hollow fiber-based liquid-phase microextraction with sweeping techniques in micellar electrokinetic chromatography for the determination of Strychnos alkaloids in human urine显示文摘A new method for the enrichment of Strychnos alkaloids in biological samples via liquid-phase microextraction (LPME) based on porous polypropylene hollow fibers in combination with on-line sweeping in micellar electrokinetic chromatography was developed. The calibration curve was linear over the range of 20-200 ng mL-1 for both strychnine and brucine in human urine sample. The detection limits (S/N=3:1) for strychnine and brucine were 1 ng mL-1 and 2 ng mL-1, respectively. The LPME-sweeping method has been successfully applied to the analysis of strychnine and brucine in real urine samples. | Xiao Huan Zang Cai Rui Li Qiu Hua Wu Chun Wang Dan Dan Han Zhi Wang | 2007 | Chinese Chemical Letters2007，18，3： | 0 |
| 7 | Chinese expert recommendations on ketogenic diet therapy for super-refractory status epilepticus显示文摘Super-refractory status epilepticus(SRSE)is a serious and life-threatening neurological condition.Ketogenic diet(KD)is a diet characterized by high fat,low carbohydrate,and moderate protein.As KD shows effectiveness in controlling seizures in more than half of SRSE patients,it can be a treatment option for SRSE.Currently,KD treatment for SRSE is based on personal experience and observational evidence has been published.In the context of a lack of a validated guideline,we convened a multicenter expert panel within the China Association Against Epilepsy(CAAE)Ketogenic Diet Commission to work out the Chinese expert recommendations on KD for SRSE.We summarize and discuss the latest clinical practice of KD for SRSE in critical care settings.Recommendations are given on patient selection,the timing of KD,diet implementation,and follow-up.More research data are needed in this area to support better clinical practice. | Xin Tong Qianyun Cai Dezhi Cao Lifei Yu Dan Sun Guang Yang Jiwen Wang Hua Li Zengning Li Juan Wang Shaoping Huang Meiping Ding Fang Fang Qun Wang Rong Luo Jianxiang Liao Jiong Qin | 2022 | Acta Epileptologica2022，5，1： | 0 |
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