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| 1 | Two stages of immiscible liquid separation in the formation of Panzhihua-type Fe-Ti-V oxide deposits,SW China显示文摘在 260 妈 Emeishan 大火的省(ELIP ) 的 Magmatic 氧化物沉积物, SW 中国和北越南,是 Fe, Ti 和 V 的重要来源。一些巨大的 magmatic Fe-Ti-V 氧化物沉积物例如 Panzhihua, Hongge,和 Baima 沉积物,很好在文学被描述并且在 Panxi 区域在分层的 mafic-ultramafic 侵入被招待,中央 ELIP。ELIP 相关的沉积物的一样的类型也远发生到南方并且在红河差错地区包括 Anyi 沉积物, Panzhihua 的大约 130 km 南方,和 Mianhuadi 沉积物。Anyi 沉积物是相对小的,但是同样在分层的 mafic 侵入被招待。Mianhuadi 沉积物有 260 妈的锆石 U-Pb 年龄并且与 ELIP 因此是同时期的。这存款易变地在指责的 Indosinian 造山运动和红河期间被变形。组合地, Mianhuadi 存款的磁铁矿比另外的存款的包含 Ti 和 V 的更小的数量,对以后的变态可能可归因。氧化物矿石存款的分发不与 ELIP 的 domal 结构有关。在 ELIP 的所有氧化物存款的一个主要特征是忍受氧化物的 gabbroic 侵入,黑花岗石 plutons 和 high-Ti 洪水暗岩的空间协会。因此,我们建议从一根披风羽毛的岩浆是进他们被发展进液体 immiscibility 的域形成二硅酸盐液体的一个浅岩浆房间的 emplaced,与一极其 Fe-Ti-rich gabbroic 作文和另外的黑花岗石。不能混合的 Fe-Ti-(P) 氧化物融化然后可以与 mafic 岩浆分开形成氧化物存款。这些存款从形成了的父母岩浆是在作文的可能的 Fe-Ti-rich picritic 并且比生产了 ELIP 的忍受硫化物的侵入的岩浆在更大的深度从充实的 asthenospheric 披风被导出。 | Mei-Fu Zhou Wei Terry Chen Christina Yan Wang Stephen A.Prevec Patricia Pingping Liu Geoffrey H.Howarth | 2013 | Geoscience Frontiers2013，4，5： | 35 |
| 2 | Nitrogen-doped fluorescence carbon dots as multi-mechanism detection for iodide and curcumin in biological and food samples显示文摘Iodine ion is one of the most indispensable anions in living organisms,particularly being an important substance for the synthesis of thyroid hormones.Curcumin is a yellow-orange polyphenol compound derived from the rhizome of Curcuma longa L.,which has been commonly used as a spice and natural coloring agent,food additives,cosmetics as well as Chinese medicine.However,excess curcumin may cause DNA inactivation,lead to a decrease in intracellular ATP levels,and trigger the tissue necrosis.Therefore,quantitative detection of iodine and curcumin is of great significance in the fields of food and life sciences.Herein,we develop nitrogen-doped fluorescent carbon dots(NCDs)as a multi-mechanism detection for iodide and curcumin in actual complex biological and food samples,which was prepared by a one-step solid-phase synthesis using tartaric acid and urea as precursors without adding any other reagents.An assembled NCDs-Hg^(2+) fluorescence-enhanced sensor for the quantitative detection of I^(-) was established based on a fluorescence“turn-off-on”mechanism in a linear range of 0.3-15μM with a detection limit of 69.4 nM and successfully quantified trace amounts of I^(-) in water samples and urine sample.Meanwhile,the as-synthesized NCDs also can be used as a fluorescent quenched sensor for curcumin detection based on the synergistic internal filtration effect(IFE)and static quenching,achieving a good linear range of 0.1-20μM with a satisfactory detection limit of 29.8 nM.These results indicate that carbon dots are potential sensing materials for iodine and curcumin detection for the good of our health. | Xiaodan Tang Hongmei Yu Brian Bui Lingyun Wang Christina Xing Shaoyan Wang Mingli Chen Zhizhi Hu Wei Chen | 2021 | Bioactive Materials2021，6，6： | 11 |
| 3 | Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction显示文摘Zika 病毒(ZIKV ) 的最近的爆发为治疗学加亮迫切需要。朊酶建筑群 NS2B-NS3 在 flaviviral polyprotein 处理期间起必要作用,并且因此代表一个吸引人的药目标。这里,我们开发了裂口酶识别直接指向 flavivirus NS2B-NS3 相互作用的 orthosteric 禁止者的基于互补的高产量的屏蔽试金。由屏蔽一个总数 2 816 同意了并且 investigational 药,我们识别了三个有势力候选人, temoporfin, niclosamide,和 nitazoxanide,,有 nanomolar 力量的 flavivirus NS2B-NS3 相互作用禁止者。显著地,在老鼠的在人的胎盘、神经的祖先房间的大多数有势力化合物, temoporfin,不是仅仅禁止的 ZIKV 复制,而且阻止的导致 ZIKV 的 viremia 和死亡当模特儿。结构的停靠建议 temoporfin 潜在地绑保持批评 NS2B 残余的 NS3 衣袋,因此禁止以一种非竞争的方式处理的 flaviviral polyprotein。当这些药已经在 USA 或另外的国家在另外的指示任何一个为临床的使用被同意了,他们由 ZIKV 和另外的 flaviviruses 为感染的管理代表有希望、容易开发的治疗。 | Zhong Li Matthew Brecher Yong-Qiang Deng Jing Zhang Srilatha Sakamuru Binbin Liu Ruili Huang Cheri A Koetzner Christina A Allen Susan A Jones Haiying Chen Na-Na Zhang Min Tian Fengshan Gao Qishan Lin Nilesh Banavali Jia Zhou Nathan Boles Menghang Xia Laura D Kramer Cheng-Feng Qin Hongmin Li | 2017 | Cell Research2017，27，8： | 11 |
| 4 | Time-dependent density-functional theory molecular-dynamics study on amorphization of Sc-Sb-Te alloy under optical excitation显示文摘Recently,all-optical memory and optical-computation properties of phase-change materials are receiving intensive attention.Because writing/erasing information in these devices is usually achieved by laser pulses,the interaction between the laser and the phase-change materials becomes a key issue for such new applications.In this work,by a time-dependent density-functional theory molecular-dynamics study,the physics underlying the optical excitation induced amorphization of Sc-Sb-Te is revealed,which goes back to superatom-like Sc-centered structural motifs.These motifs are found to be still robust under the excitation. | Xue-Peng Wang Xian-Bin Li Nian-Ke Chen Junhyeok Bang Ryky Nelson Christina Ertural Richard Dronskowski Hong-Bo Sun Shengbai Zhang | 2020 | npj Computational Materials2020，，1： | 5 |
| 5 | The safety of tenofovir disoproxil fumarate for the treatment of HIV infection in adults: the first 4 years显示文摘 | Mark R Nelson Christine Katlama Julio S Montaner David A Cooper Brian Gazzard Bonaventura Clotet Adriano Lazzarin Knud Schewe Joep Lange Christina Wyatt Sue Curtis Shan-Shan Chen Stephen Smith Norbert Bischofberger James F Rooney | 2007 | AIDS2007，，10： | 2 |
| 6 | Morphotype pattern of Norwegian Sea deep sea benthic foraminifera and ecological implication 显示文摘 | CORLISS B H CHEN CHRISTINA | 1988 | Geology1988，16，： | 1 |
| 7 | Magnetic pinning strength for the new SM-TM magnetic materials for use up to 550 ℃显示文摘 | CHEN Martin Walmer S | 2000 | J Appl Phys2000，87，9： | 1 |
| 8 | Dichlorodiphenyltrichloroethane and risk of hepatocellular carcinoma显示文摘 | E. Christina Persson Barry I. Graubard Alison A. Evans W. Thomas London Jean‐Philippe Weber Alain LeBlanc Gang Chen Wenyao Lin Katherine A. McGlynn | 2012 | Int. J. Cancer2012，，9： | 1 |
| 9 | Nature-based recreation for the elderly in urban areas:assessing opportunities and demand as planning support显示文摘Background:With elderly people comprising a growing share of the population,landscape planners need to consider their specific requirements to enhance the opportunities for them to engage in nature-based recreation(NBR).However,few studies have spatially assessed the recreation potential,demand,and opportunities for elderly people in cities.Thus,this paper aimed to spatially model and investigate the NBR opportunities for and demand of elderly people in urban areas.A spatial framework based on the ESTIMAP recreation model was developed,considering special factors to better reflect elderly people’s preferences regarding NBR at the city scale.In particular,NBR opportunities were assessed considering landscape aesthetics,various types of facilities,and proximity.The street network was used to understand elderly people’s walking behaviours regarding green spaces and related facilities.Results:A case study in Hannover,Germany,demonstrated the applicability of the proposed method.The results illustrate the spatial heterogeneity of recreation options for the elderly.Only parts of Hannover’s green spaces offer high recreation opportunities for elderly people.Many of the existing green spaces lack diverse landscape compo-nents and sufficient supply of facilities,resulting in a compromise to aesthetics and recreational opportunities.Conclusions:The proposed method contributes to research on spatial planning and environmental justice by incorporating vulnerable groups’preferences and needs in spatially assessing NBR.The planning implications highlight pocket gardens and greenways connecting communities and parks as development opportunities in the city. | Chen Wen Christian Albert Christina von Haaren | 2022 | Ecological Processes2022，11，1： | 1 |
| 10 | In vivo Reduction of Hepatitis B Virus Antigenemia and Viremia by Antisense Oligonucleotides显示文摘 | Gaetan Billioud Robert L. Kruse Melissa Carrillo Christina Whitten-Bauer Dacao Gao Aneeza Kim Leon Chen Michael L. McCaleb Jeffrey R. Crosby Robert Hamatake Zhi Hong Urtzi Garaigorta Eric Swayze Karl-Dimiter Bissig Stefan Wieland | 2015 | Journal of Hepatology2015，，： | 1 |
| 11 | Electrical properties of heterogeneously doped yttria stabilized zirconia显示文摘 | Binod Kumara Christina Chen | 2005 | Journal of Power Sources2005，，140： | 1 |
| 12 | Fumonisin B 1 and risk of hepatocellular carcinoma in two Chinese cohorts显示文摘 | E. Christina Persson Vikash Sewram Alison A. Evans W. Thomas London Yvette Volkwyn Yen-Ju Shen Jacobus A. Van Zyl Gang Chen Wenyao Lin Gordon S. Shephard Philip R. Taylor Jin-Hu Fan Sanford M. Dawsey You-Lin Qiao Katherine A. McGlynn Christian C. Abnet | 2011 | Food and Chemical Toxicology (-)2011，，3： | 1 |
| 13 | Differential effects of sorafenib on liver versus tumor fibrosis mediated by stromal‐derived factor 1 alpha/C‐X‐C receptor type 4 axis and myeloid differentiation antigen–positive myeloid cell infiltration in mice显示文摘 | Yunching Chen Yuhui Huang Thomas Reiberger Annique M. Duyverman Peigen Huang Rekha Samuel Lotte Hiddingh Sylvie Roberge Christina Koppel Gregory Y. Lauwers Andrew X. Zhu Rakesh K. Jain Dan G. Duda | 2014 | Hepatology2014，，4： | 1 |
| 14 | A low voltage mixer with improved noise figure 显示文摘 | CHEN C H CHIANG P Y CHRISTINA F J | 2009 | IEEE Microwave and Wireless Components Letters2009，19，2： | 1 |
| 15 | LRH1 promotes pancreatic cancer metastasis显示文摘 | Qiushi Lin Arihiro Aihara Waihong Chung Yu Li Xuesong Chen Zheping Huang Shaofan Weng Rolf I. Carlson Christina Nadolny Jack R. Wands Xiaoqun Dong | 2014 | Cancer Letters2014，，： | 1 |
| 16 | Nonlinear Least Squares Estimation of Log-ACD Models显示文摘 | Zhao CHEN Wei LIU Christina Dan WANG Wu-qing WU Yao-hua WU | 2018 | Acta Mathematicae Applicatae Sinica2018，34，3： | 1 |
| 17 | 上海天文馆显示文摘上海天文馆坐落于滴水湖畔,总面积约3.8万m^(2)作为上海科技馆分馆,是全球规模最大的天文学主题博物馆。其致力于营造沉浸式体验,让游客可以与各种天文现象直接互动,并通过对比例、形态以及光线的细致处理,提升人们对于太阳和地球轨道运动之间的基本关系的认知。 | 无 V.Guy Maxwell Grace Chen Wei Wei Kuang Charles Wolf Anthony Guaraldo Jorge Arias Margarita Calero Michael Caton Christina Ciardullo Eugene Colberg Regina Jiang Jörg Kiesow Aidan Kim Stefan Knust Xinya Li Francelle Lim Xiaoyun Mao David Monnar Nikita Payusov James Rhee Yong Kyun Roh Miya Ruan Na Sun Eric Tsui Stephanie Tung Charles Wong David Yu Fred Zhang | 2022 | 建筑实践2022，，5： | 1 |
| 18 | Plasma MicroRNAs as Novel Biomarkers for Patients with Intraductal Papillary Mucinous Neoplasms of the Pancreas显示文摘 | Jennifer Permuth-Wey Dung-Tsa Chen William J. Fulp Sean J. Yoder Yonghong Zhang Christina Georgeades Kazim Husain Barbara Ann Centeno Anthony M. Magliocco Domenico Coppola Mokenge Malafa | 2015 | Cancer Prevention Research2015，，9： | 1 |
| 19 | Conservation and characterization of unique porcine interstitial telomeric sequences显示文摘Telomeres are composed of TTAGGG repeats and located at the ends of chromosomes. Telomeres protect chromosomes from instability in mammals, including mice and humans. Repetitive TTAGGG sequences are also found at intrachromosomal sites, where they are named as interstitial telomeric sequences (ITSs). Aberrant ITSs are implicated in chromosomal instability and found in cancer cells. Interestingly, in pigs, vertebrate telomere sequences TTAGGG (vITSs) are also localized at the centromeric region of chromosome 6, in addition to the end of all chromosomes. Surprisingly, we found that botanic telomere sequences, TTTAGGG (bITSs), also localize with vITSs at the centromeric regions of pig chromosome 6 using telomere fluorescence in situ hybridization (FISH) and by comparisons between several species. Furthermore, the average lengths of vITSs are highly correlated with those of the terminal telomeres (TTS). Also, pig ITSs show a high incidence of telomere doublets, suggesting that pig ITSs might be unstable and dynamic. Together, our results show that pig cells maintain the conserved telomere sequences that are found at the ITSs from of plants and other vertebrates. Further understanding of the function and regulation of pig ITSs may provide new clues for evolution and chromosomal instability. | JI GuangZhen LIU Kai CHEN ChengBin RUAN WeiMin GLYTSOU Christina YANG Yang OKUKA Maja SONG WenQing GAGOS Sarantis LINing LIU Lin | 2012 | Science China(Life Sciences)2012，55，12： | 1 |
| 20 | Kinetics of photocatalytic oxidation of trace organic compounds over titanium dioxide显示文摘 | Chen Paris Hanglay Jenq Christina H | 1998 | Environmental international1998，24，8： | 1 |
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