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| 1 | Multispectral Plasmon of Anisotropic Core-shell Gold Nanorods@SiO2: Dual-band Absorption Enhancement with Coupling Dye Molecules显示文摘 | CHE Yuping WANG Yang YOU Tingting CHANG Huaiqiu YIN Penggang ZHAI Jin | 2018 | Chemical Research in Chinese Universities2018,34,5: | 3 |
| 2 | TLR3 activation induces S100A7 to regulate keratinocyte differentiation after skin injury显示文摘Human S100A7 (psoriasin) is highly expressed in psoriasis and other inflammatory diseases; however, the function of S100A7 in wound repair remains largely unknown. Here we demonstrated that skin injury increased the expression of S100A7. Damaged cells from wounded skin induced the expression of S100A7 via the activation of Toll-like receptor 3 (TLR3) followed by the activation of p38 MAPK. S100A7, in turn, acted on keratinocytes to induce the expression of terminal differentiation marker gene loricrin through the activation of p38 MAPK and caspase-1. The differentiation of keratinocytes induced by S100A7 resulted in skin stratification, thus efficiently promoting wound closure. Taken together, our results demonstrate that the activation of TLR3 accelerates wound closure via the induction of S100A7 to induce keratinocyte differentiation. These findings also provide new insights into the development of different forms of treatment with skin wounds. | Hu Lei Yue Wang Tian Zhang Leilei Chang Yelin Wu Yuping Lai | 2017 | Science China(Life Sciences)2017,60,2: | 3 |
| 3 | De novo DNA methylation during monkey pre-implantation embryogenesis显示文摘首领 embryogenesis 的批评 epigenetic 规定必要 DNA methylome 变化。这里,我们在培植前恒河猴胚胎以及用定序方法的优化基于 tagmentation 的整个染色体的重亚硫酸盐学习的男、女的配偶子报导 DNA methylation 的染色体宽的作文, patterning,和阶段特定的动力学。我们证明在授精之上,父亲、母亲的染色体经历活跃 DNA demethylation,和染色体宽的 de novo DNA methylation 也在一样的时期被开始。由 8 房间阶段, remethylation 变得比 demethylation 更显著,导致全球 DNA methylation 的增加。基因的倡导者与氧化 phosphorylation 联系了,建议精力新陈代谢的这个模式不能被赞成是优先地在 8 房间阶段的 remethylated。在啮齿类动物不同, X 染色体 inactivation 没在猴子培植前开发期间被观察。我们的学习提供蜡的第一幅全面插图并且衰退 DNA methylation 动力学的阶段。最重要地,我们的 DNA methyltransferase loss-of-function 分析显示 DNA methylation 影响早猴子 embryogenesis。 | Fei Gao Yuyu Niu Yi Eve Sun Hanhn Lu Yongchang Chen Siguang Li Yu Kang Yuping Luo Chenyang Ni Juehua Yu Chang Li Nianqin Sun Wei Si Hong Wang Weizhi Ji Tao Tan | 2017 | Cell Research2017,27,4: | 1 |
| 4 | A High Capacity Rever- sible Data Hiding Scheme Using Orthogonal Projection and Prediction Error Modification显示文摘 | Hong W Chen T S Chang Yuping | 2010 | Signal Processing2010,90,11: | 1 |
| 5 | Inverse-time Backup Protection Based on Unified Characteristic Equation for Distribution Networks with High Proportion of Distributed Generations显示文摘The setting work of backup protection using steady-state current is tedious,and mismatches occasionally occur due to the increased proportion of distributed generations(DGs)connected to the power grid.Thus,there is a practical need to study a backup protection technology that does not require step-by-step setting and can be adaptively coordinated.This paper proposes an action sequence adaptive to fault positions that uses only positive sequence fault component(PSFC)voltage.Considering the influence of DGs,the unified time dial setting can be obtained by selecting specific points.The protection performance is improved by using the adjacent upstream and downstream protections to meet the coordination time interval in the case of metallic faults at the near-and far-ends of the line.Finally,the expression and implementation scheme for inverse-time backup protection(ITBP)based on the unified characteristic equation is given.Simulation results show that this scheme can adapt to DG penetration scenarios and can realize the adaptive coordination of multi-level relays. | Nana Chang Guobing Song Zhongxue Chang Yuping Zheng Xingang Yang | 2024 | Journal of Modern Power Systems and Clean Energy2024,12,1: | 0 |
| 6 | Inherent thermal-responsive strategies for safe lithium batteries显示文摘Safe batteries are the basis for next-generation application scenarios such as portable energy storage devices and electric vehicles,which are crucial to achieving carbon neutralization.Electrolytes,separators,and electrodes as main components of lithium batteries strongly affect the occurrence of safety accidents.Responsive materials,which can respond to external stimuli or environmental change,have triggered extensive attentions recently,holding great promise in facilitating safe and smart batteries.This review thoroughly discusses recent advances regarding the construction of high-safety lithium batteries based on internal thermal-responsive strategies,together with the corresponding changes in electrochemical performance under external stimulus.Furthermore,the existing challenges and outlook for the design of safe batteries are presented,creating valuable insights and proposing directions for the practical implementation of safe lithium batteries. | Jia-Xin Guo Chang Gao He Liu Feng Jiang Zaichun Liu Tao Wang Yuan Ma Yiren Zhong Jiarui He Zhi Zhu Yuping Wu Xin-Bing Cheng | 2024 | Journal of Energy Chemistry2024,89,2: | 0 |
| 7 | Petroleum Generation Kinetics and Geological Implications for Jurassic Hydrocarbon Source Rocks,Hongqi Depression,Hailar Basin,Northeast China显示文摘A sample from the Jurassic Tamulangou Fm.and two comparison samples from the Cretaceous Fm.were used to document the hydrocarbon generation kinetics and phase behaviors at two heating rates using the confined gold tube system.The results show that the different heating rates affect the reaction rates,paths and levels of organic matter evolution.The average activation energy and dominant frequency activation energy of liquid hydrocarbon are significantly lower than those of gaseous.Moreover,igneous intrusion had a positive effect on the blooming,enrichment and preservation of organic matter,promoting a Ro increase of 0.09%–1.07%in the Jurassic Tamulangou Fm.Two models were used to simulate the normal and abnormal evolution caused by thermal events combined hydrocarbon generation kinetic parameters.Thermal simulation analysis shows that oil generation was initially slow and then increased rapidly until a burial depth of 1500 m was reached at~128 Ma.The largest hydrocarbon expulsion began at~120 Ma,corresponding to a burial depth of 2450 m.The maximum cumulative yield is 510 mg/g TOC,and it is still in the peak period of hydrocarbon generation,which demonstrates a favorable potential for hydrocarbon exploration. | XIE Mingxian MA Feng CHEN Guangpo LIU Chang XIAO Rong SU Yuping ZHANG Chengjun | 2023 | Acta Geologica Sinica(English Edition)2023,97,2: | 0 |
| 8 | Ribonucleotide reductase M2 (RRM2): Regulation, function and targeting strategy in human cancer显示文摘Ribonucleotide reductase M2(RRM2)is a small subunit in ribonucleotide reduc-tases,which participate in nucleotide metabolism and catalyze the conversion of nucleotides to deoxynucleotides,maintaining the dNTP pools for DNA biosynthesis,repair,and replication.RRM2 performs a critical role in the malignant biological behaviors of cancers.The structure,regulation,and function of RRM2 and its inhibitors were discussed.RRM2 gene can produce two transcripts encoding the same ORF.RRM2 expression is regulated at multiple levels during the processes from transcription to translation.Moreover,this gene is associated with resistance,regulated cell death,and tumor immunity.In order to develop and design inhibitors of RRM2,appropriate strategies can be adopted based on different mechanisms.Thus,a greater appreciation of the characteristics of RRM2 is a benefit for understanding tumorigenesis,resistance in cancer,and tumor microenvironment.Moreover,RRM2-targeted therapy will be more attention in future therapeutic approaches for enhancement of treatment effects and amelioration of the dismal prognosis. | Zanwen Zuo Zerong Zhou Yuzhou Chang Yan Liu Yuping Shen Qizhang Li Lei Zhang | 2024 | Genes & Diseases2024,11,1: | 0 |