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| 1 | An experimental research of Weining granule in treating gastric precancerous lesions显示文摘目的将在胃的癌症前期的损害的治疗调查 Weining 小粒的潜在的治疗学的效果和机制。六十只老鼠随机被分到一个空白的组或一个模型组或到的方法收到酸或高的 retinoic -- ,中等 -- 或低 -- Weining 的剂量小粒。动物的一般条件在治疗前后被遵守。在胃的 mucosal pathohistology, telomerase 活动,增长索引(PI ) 和 apoptosis 索引(AI ) 的变化被测量。结果将军调节,包括活动并且吃,与肠的组织变形(IM ) ,不正常的增生(ATP ) 或是比在模型的那些显著地低的积极 telomerase 活动组织的老鼠有的数字在所有 Weining-granule-treated 组被改进(P <
0.05 或 P <
0.01 ) 。与模型组相比, Weining 小粒的所有剂量显著地减少了 PI (P <
0.01 ) 并且增加的 AI (P <
0.05 ) 。结论 Weining 小粒可以由禁止 telomerase 活动和胃的癌症房间并且由加速他们的 apoptosis 的增长为胃的癌症前期的损害的治疗提供一个治疗学的好处。 | Xing Deng Jian Liang Donghua Liu Chaoyang Zhu Longhua Li Likui Qin | 2009 | The Chinese-German Journal of Clinical Oncology2009，8，3： | 6 |
| 2 | Exploring porous zeolitic imidazolate frame work-8(ZIF-8)as an efficient filler for high-performance poly(ethyleneoxide)-based solid polymer electrolytes显示文摘Nano Research volume 13,pages2259–2267(2020)Cite this article 277 Accesses 1 Altmetric Metrics details Abstract The incorporation of inorganic fillers into poly(ethyleneoxide)(PEO)-based solid polymer electrolytes(SPEs)is well known as a low-cost and effective method to improve their mechanical and electrochemical properties.Porous zeolitic imidazolate framework-8(ZIF-8)is firstly used as the filler for PEO-based SPEs in this work.Due to the introduction of ZIF-8,an ionic conductivity of 2.2×10^−5 S/cm(30℃)is achieved for the composite SPE,which is one order of magnitude higher than that of the pure PEO.ZIF-8 also accounts for the broader electrochemical stability window and lithium ion transference number(0.36 at 60℃)of the composite SPE.Moreover,the improved mechanism of ZIF-8 to the composite SPE is investigated by zeta potential and Fourier transform infrared spectrograph characterizations.The stability at the composite SPE/lithium interface is greatly enhanced.The LiFePO4||Li cells using the composite SPE exhibit high capacity and excellent cycling performance at 60℃,i.e.,85%capacity retention with 111 mA·h/g capacity retained after 350 cycles at 0.5 C.In comparison,the cells using the pure PEO show fast capacity decay to 74 mA·h/g maintaining only 68 capacity.These results indicate that the PEO-based SPEs with ZIF-8 are of great promise for the application in solid-state lithium metal batteries. | Zhiwen Lei Jinlai Shen Weide Zhang Qingrong Wang Jun Wang Yonghong Deng Chaoyang Wang | 2020 | Nano Research2020，13，8： | 5 |
| 3 | Antimony transformation and mobilization from stibnite by an antimonite oxidizing bacterium Bosea sp. AS-1显示文摘Soils and waters are heavily contaminated by antimony in Xikuangshan(XKS)mine area.It is widely accepted that oxidative dissolution of sulfide minerals and aqueous dissolution are the most prevalent geochemical mechanisms for the release of Sb to the environment.Bosea sp.AS-1 is an antimonite-oxidizer isolated from the mine slag in Xikuangshan Sb mine.Whole genome sequencing revealed the presence of multiple sulfur-oxidizing genes,antimony(Sb)metabolism genes and carbon fixation genes in AS-1 s genome.We therefore hypothesized that under oxic conditions,AS-1 could mediate the oxidation of sulfide and Sb(Ⅲ)in stibnite(Sb_(2)S_(3))and lead to the release of Sb.Indeed,strain AS-1 was discovered as an autotrophic Sb(Ⅲ)-oxidizer.Antimony mobilization studies conducted with strain AS-1showed significantly enhanced mobilization of Sb,and complete oxidation of released Sb and sulfur to Sb(V)and sulfate.In addition,AS-1 induced a faster release of Sb under heterotrophic condition,and new acicular minerals might form.These findings support the hypothesis that microorganisms play an important role in the mobilization and transformation of Sb in XKS mine area and may contribute to our further understanding of the Sb biogeochemical redox cycle in natural environment. | Li Xiang Chaoyang Liu Deng Liu Liyuan Ma Xuan Qiu Hongmei Wang Xiaolu Lu | 2022 | Journal of Environmental Sciences2022，34，1： | 3 |
| 4 | A novel three primers PCR (TP-PCR) method to obtain recombinant DNA molecule independent of restriction enzyme显示文摘In this note, we report a novel and efficient three primers PCR (TP-PCR) method to rapidly generate recombinant DNA molecule at precise junction between two arbitrary DNA fragments. TP-PCR method is characterized by its reaction system with two templates and three primers, which can produce a recombinant DNA molecule in one PCR reaction. The main advantages of this method are the independence of sequences at the recombination site, the rapid-ness, and the easy establishment of adequate conditions. This method has been successfully applied to constructing a fusion protein gene, sck gene. | Chaoyang Deng Guisheng Song Junwang Xu Zhen Zhu | 2002 | Chinese Science Bulletin2002，47，24： | 2 |
| 5 | An improved method for infectious bursal disease virus rescue using RNA polymerase II system显示文摘 | Xiaole Qi Yulong Gao Honglei Gao Xiaoyun Deng Zhigao Bu Xiaoyan Wang Chaoyang Fu Xiaomei Wang | 2007 | Journal of Virological Methods2007，，1： | 1 |
| 6 | Environmental impacts of mining of Ni-Mo black shale-hosted deposits in the Zunyi region, southern China: Preliminary results of the study of toxic metals in the system rock-soil-plant 显示文摘 | Pasaya J Kribek B Zak K Li Chaoyang Deng Hailin Gao Zhenmin Luo Taiji Zeng Mingguo | 2003 | Bull Geosci2003，78，3： | 1 |
| 7 | Propagation properties of beam generated by Gaussian mirror resonator显示文摘 | Chaoyang Wei Kui Yi etal | 2006 | Optics Communications2006，258，： | 1 |
| 8 | A three-dimensional crosslinked chitosan sulfate network binder for high-performance Li-S batteries显示文摘Poor cycling performance caused by the shuttle effect of polysulfides is the main obstacle in the development of advanced lithium-sulfur(Li-S)batteries.Functional polymer binders with polar groups can effectively adsorb polysulfides chemically,thereby suppressing the shuttle effect.Herein,a robust three-dimensional crosslinked polymer network,which demonstrates excellent mechanical property and strong affinity for polysulfides,is prepared by the aldimine condensation and coordination reactions.The crosslinked chitosan sulfate network(CCSN)significantly enhances the cycling performance and rate capability of the sulfur cathode.The CCSN-based sulfur cathode exhibits a high initial discharge capacity of 824 m Ah g^(-1) with only 0.082%average capacity loss per cycle at 1 C.At a high rate of 4 C,the cathode exhibits a high capacity retention of 84.8%after 300 cycles.Moreover,the CCSN-based sulfur cathode exhibits an excellent cycling performance at a high sulfur loading of 2.5 mg cm^(-2),which indicates the excellent mechanical strength and binding performance of the CCSN binder for high-energy density Li-S batteries.This study demonstrates a viable approach for developing high-performance Li-S batteries for practical application. | Jianwen Feng Huan Yi Zhiwen Lei Jun Wang Hongbo Zeng Yonghong Deng Chaoyang Wang | 2021 | Journal of Energy Chemistry2021，30，5： | 1 |
| 9 | Recent advances in fruit crop genomics显示文摘In recent years,dramatic progress has been made in the genomics of fruit crops.The publication of a dozen fruit crop genomes represents a milestone for both functional genomics and breeding programs in fruit crops.Rapid advances in high-throughput sequencing technology have revolutionized the manner and scale of genomics in fruit crops.Research on fruit crops is encompassing a wide range of biological questions which are unique and cannot be addressed in a model plant such as Arabidopsis.This review summarizes recent achievements of research on the genome,transcriptome,proteome,miRNAs and epigenome of fruit crops. | Qiang XU Chaoyang LIU Manosh Kumar BISWAS Zhiyong PAN Xiuxin DENG | 2014 | Frontiers of Agricultural Science and Engineering2014，1，1： | 1 |
| 10 | Effect of Kupffer cells depletion on ABC phenomenon induced by Kupffer cells-targeted liposomes显示文摘Accelerated blood clearance(ABC) phenomenon is common in many PEGylated nanocarriers, whose mechanism has not been completely elucidated yet. In this study, the correlation between Kupffer cells(KCs) and ABC phenomenon has been studied by KCs-targeted liposomes inducing ABC phenomenon and KCs depletion. In other words, the 4-aminophenyl-α-D-mannopyranoside(APM) lipid derivative DSPE-PEG 2000-APM(DPM), and 4-aminophenyl-β-L-fucopyranoside(APF) lipid derivative DSPE-PEG 2000-APF(DPF) were conjugated and modified on alendronate sodium(AD) liposomes to specifically target and deplete KCs. The dualligand modified PEGylated liposomes(MFPL) showed stronger ability to damage KCs in vitro and in vivo, which also could indirectly illustrate that dual-ligand modification could better target KCs. Besides, the hepatic biodistribution and pharmacokinetics could directly prove that MFPL had a stronger targeting ability to KCs. In addition, in depletion rats, plasma concentration and splenic biodistribution of MFPL and PEGylated liposomes(PL) were significantly elevated and hepatic biodistribution was significantly reduced, which demonstrated that KCs played an important role on elimination of nanoparticles. What’s more, ABC phenomenon of the secondary injection of PL was stronger in KCs depletion rats than that in normal rats, which indicated that depletion of KCs prolonged the circulation of PL in the first injection repeatedly stimulating B-cells in the marginal region of the spleen and causing it to secrete more IgM antibodies. This could also illustrate that anti-PEG IgM takes up a major station compared with KCs. Most important of all, KCs-targeted liposomes could induce a stronger ABC phenomenon than PL in normal rats, which declared that based on the same IgM concentration, the more the KCs were stimulated, the stronger ABC phenomenon was induced. However, in depletion rats, this difference of ABC phenomenon between PL and MFPL could no more exist, further demonstrating that KCs could participate and play a certain role in the ABC phenomenon. | Chaoyang Lai Cong Li Mengyang Liu Qiujun Qiu Xiang Luo Xinrong Liu Ling Hu Yihui Deng Yanzhi Song | 2019 | Asian Journal of Pharmaceutical Sciences2019，14，4： | 1 |
| 11 | The electronic structure and optical properties of Ca_(3)(Mn_(1-x)Ti_(x))_(2)O_(7) from first-principle calculations显示文摘The electronic structure and optical properties of Ca_(3)(Mn_(1-x)Ti_(x))_(2)O_(7)(x¼0,1/8,2/8,3/8,4/8)were studied by first-principle calculations within the generalized gradient approximation approaches(GGA).The lattice constants of Ca_(3)(Mn_(1-x)Ti_(x))_(2)O_(7) increase with the increase of Ti^(4+)content caused by the substitution of Ti^(4+)with larger ionic radius for Mn^(4+).Ca_(3)(Mn_(1-x)Ti_(x))_(2)O_(7) is a direct band gap semiconductor,and the band gap(Eg)increases with the increase of Ti^(4+)content.From the density of states,the introduction of Ti-3d states can weaken the effects of Mn-3d states on the bottom of conduction band and has little influence on O-2p states on the top of valence band.The introduction of nonmagnetic Ti^(4+)ions can weaken the magnetism of Ca_(3)(Mn_(1-x)Ti_(x))_(2)O_(7).According to the Mulliken population analysis,it is found that the introduction of Ti^(4+)enhances the electronic accepting capacity of oxygen ions and enhances the electronic losing capacity of manganese ions.The bond strength of Ti–O covalent bond is stronger than that of Mn–O covalent bond.Furthermore,the optical properties of Ca_(3)(Mn_(1-x)Ti_(x))_(2)O_(7) was calculated.As Ti^(4+)content increases,the absorption edge of Ca_(3)(Mn_(1-x)Ti_(x))_(2)O_(7) has a blue shift,the static refractive index n0 decreases,the static dielectric constant'1(0)decreases,the position of loss peak moves to higher energy. | Fengqi Wang Wei Cai Chunlin Fu Rongli Gao Gang Chen Xiaoling Deng Zhenhua Wang Chaoyang Zhang | 2019 | Journal of Advanced Dielectrics2019，9，1： | 0 |
| 12 | Natural Cocoons Enabling Flexible and Stable Fabric Lithium–Sulfur Full Batteries显示文摘Lithium–sulfur batteries are highly appealing as highenergy power systems and hold great application prospects for flexible and wearable electronics.However,the easy formation of lithium dendrites,shuttle effect of dissolved polysulfides,random deposition of insulating lithium sulfides,and poor mechanical flexibility of both electrodes seriously restrict the utilization of lithium and stabilities of lithium and sulfur for practical applications.Herein,we present a cooperative strategy employing silk fibroin/sericin to stabilize flexible lithium–sulfur full batteries by simultaneously inhibiting lithium dendrites,adsorbing liquid polysulfides,and anchoring solid lithium sulfides.Benefiting from the abundant nitrogen-and oxygen-containing functional groups,the carbonized fibroin fabric serves as a lithiophilic fabric host for stabilizing the lithium anode,while the carbonized fibroin fabric and the extracted sericin are used as sulfiphilic hosts and adhesive binders,respectively,for stabilizing the sulfur cathode.Consequently,the assembled Li–S full battery provided a high areal capacity(5.6 mAh cm−2),limited lithium excess(90%),a high volumetric energy density(457.2 Wh L^(−1)),high-capacity retention(99.8%per cycle),and remarkable bending capability(6000 flexing cycles at a small radius of 5 mm). | Yanan An Chao Luo Dahua Yao Shujing Wen Peitao Zheng Shangsen Chi Yu Yang Jian Chang Yonghong Deng Chaoyang Wang | 2021 | Nano-Micro Letters2021，13，5： | 0 |
| 13 | Oxygen isotope as a tracer of REE fractionation in water-rock interaction显示文摘STABLE oxygen isotope is not only an effective approach to tracing water-rock interactions, but also canprovide much information about ore-forming temperature and source and evolution of ore fluids in thestudy of hydrothermal deposits. The rare-earth elements (REE) can be used to trace the sources ofore-forming materials and can also, to some extent, indicate the physical and chemical properties of fluids in the geochemical processes. The combination of these two aspects of research can effectivelyprobe into the geochemical behavior and evolution of REE in the process of water-rock interaction duringhydrothermal ore deposition. On the other hand, the essence of REE as tracers in hydrothermal mineralization can be better understood. In this note the Lemachang independent Ag deposit in northeastern Yunnan is selected for a case study. | DENG Hailin~1, LI Chaoyang~1, ZHOU Yunman~2 and WANG Chongwu~2 1. Open Laboratory of Ore Deposit Geochemistry, Institute of Geochemistry Chinese Academy of Sciences, Guiyang 550002, China 2. No.1 Geological Party, Yunnan Bureau of Geology and Mineral Resources, Xundian 655205, China | 1999 | Chinese Science Bulletin1999，44，S2： | 0 |
| 14 | Sulfur isotope geochemistry of the Lemachang independent Ag deposit, northeastern Yunnan——A concurrent discussion on the mechanism of sulfur isotope equilibrium between barite and freibergite below 300℃显示文摘IN the study of hydrothermal deposits sulfur isotopes bear much information about the source of sulfur,ore-forming temperature, the evolution of ore-forming fluids and the mechanism of metallogenesis. Todetermine whether sulfur isotopes reach equilibrium between fluids and sulfur-bearing minerals precipitated from the former and among the sulfur-bearing minerals is the key to the application of sulfur isotopegeochemistry to geological problems. As it has been commonly accepted that sulfur isotopic equilibrium could not be reached between sulfate and sulfide below 350℃, little attention has been paid to thepossible mechanism of sulfur isotope equilibrium between sulfate and sulfide below 300℃. However, this note presents an example to show sulfur isotope equilibrium between barite and sulfate | DENG Hailin~1, LI Chaoyang~1, ZHOU Yunman~2 and WANG Congwu~2 1. Open Laboratory of Ore Deposit Geochemistry, Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550002, China 2. No.3 Braneh of No.1 Geology Party, Yunnan Bureau of Geology and Mineral Resources, Xundian 655205, China | 1999 | Chinese Science Bulletin1999，44，S2： | 0 |
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