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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 3 | Mammography of ductal carcinoma in situ of the breast: Review of 909 cases with radiographic–pathologic correlations显示文摘 | Béatrice Barreau Isabelle de Mascarel Caroline Feuga Gaétan MacGrogan Marie-Hélène Dilhuydy Véronique Picot Jean-Marie Dilhuydy Christine Tunon de Lara Emmanuel Bussières I. Schreer | 2005 | European Journal of Radiology2005，，1： | 2 |
| 4 | 梨花女子大学 校园谷显示文摘"校园谷"项目场地紧邻一个更大的校园和南边的新村,复杂的场地环境要求建筑"大于基地"。建筑师以一种全球化的地景式设计策略将梨花大学校园的组织结构融入到城市中。"校园谷"与"运动带相结合,创造出新型地貌,以一系列方式影响着周围环境。运动带和校园谷一样是多重事物的结合体。它是进入梨花大学校园的新大门,是日常运动消闲的新去处,是年度节庆或盛典的举办地,还是名副其实的将大学带入城市的纽带。 | André Morin Luca Reale Gaёlle Lauriot-Prévost Frederico de Matteis | 2013 | 城市环境设计2013，，9： | 2 |
| 5 | Proportionate incresease of fibrinogen and albumin synthesis in nephritic patients:Measurements with stable isotopes显示文摘 | De Sain-van der Velden MGM Kaysen GA De Meek K et la | 1998 | Kidney Int1998，53，1： | 2 |
| 6 | The vertebral artery: its relationship with adjoining tissues in its course intra and inter transverse procwsses in man 显示文摘 | Chopard RP de Miranda Neto MH Lucas GA | 1992 | Rev Patel Med1992，110，6： | 1 |
| 7 | Human brain activity related to speed discrimination tasks显示文摘 | Orban GA Dupont P De Bruyn B | 1998 | Exp Brain Res1998，122，1： | 1 |
| 8 | Bacterial proteins with cleaved or uncleared signal peptides of the general secretorypathway显示文摘 | de Souza GA Leversen NA Mhlen H | 2011 | J Proteomics2011，75，2： | 1 |
| 9 | On the relationship between thermal emissivity and the normalized difference vegetation index for natural surfaces显示文摘 | van de GA Owe M | 1993 | International Journal of Remote Sensing1993，14，6： | 1 |
| 10 | Increased myocardial-metaiodobenzylguanidine uptake after enalapril treatment in patients with chronic heart failure显示文摘 | Somsen GA van Vlies B de Milliano PA | 1996 | Heart1996，76，3： | 1 |
| 11 | Haemodynamic and metabolic changes during major liver resection with age of hepatic total vascular exclusion显示文摘 | De Cosmo GA Adducci E Gualtieri EM | 2000 | Int Surg2000，85，3： | 1 |
| 12 | Neuroendocrine pharmacology of stress 显示文摘 | Carrasco GA Van de Kar LD | 2003 | Eur J Phamarcol2003，463，13： | 1 |
| 13 | Chemotherapeutic managenment of stage Ⅳ non-small cell lung cancer显示文摘 | Socinski MA Morris DE Masters GA | | 0，，1： | 1 |
| 14 | The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide显示文摘 | Schellekens GA Visser H de Jong BA | | 0，，1： | 1 |
| 15 | Inhibiting MMP activity prevents the development of endometriosis in the chicken chorioallantoic membrane model 显示文摘 | Nap AW Dunselman GA de Goeij AF | 2004 | Hum Reprod2004，19，： | 1 |
| 16 | Chemotherapeutic management of stage Ⅳ non-small cell lung concer显示文摘 | Socinski MA Morris DE Masters GA | 2003 | Chest2003，123，1： | 1 |
| 17 | Chronic cerebrovascular insuriciency induces dementia-like deficits inaged rats显示文摘 | De la Torre JC Fortin T Park GA | 1992 | Brain Res1992，582，2： | 1 |
| 18 | 显示文摘 | Everson SA Goldberg DE Kaplan GA | 1996 | Psyvhosom Med1996，58，： | 1 |
| 19 | The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide 显示文摘 | Schellekens GA Visser H de Jong BAW | 2000 | Arthritis Rheum2000，，： | 1 |
| 20 | Synergistic interaction between sphingomyelin and gemcitabine potentiates ceramide-mediated apoptosis in pancreatic cancer显示文摘 | Modrak DE Cardillo TM Newsome GA | 2004 | Cancer Res2004，64，22： | 1 |
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