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69篇 您的检索式:作者名="DENG Jianjun"
    题名 作者 年代 出处 被引量
1RNA N^6-methyladenosine modification in cancers: current status and perspectives显示文摘Xiaolan Deng Rui Su Hengyou Weng Huilin Huang Zejuan Li Jianjun Chen 2018Cell Research2018,28,5:55
2Risk assessment and validation of flood disaster based on fuzzy mathematics显示文摘Floods often take place around rivers and plains,which indicates a higher risk of flooding in these areas.This paper adopts fuzzy comprehensive assessment(FCA),simple fuzzy classification(SFC),and the fuzzy similarity method(FSM) to assess flood disaster risk in Kelantan,Malaysia.Validation data,such as the flooded area,paddy area,urban area,residential area,and refuges,were overlaid to validate and analyze the accuracy of flood disaster risk.The results show that(1) 70-75% of flooded areas lie within the higher and high-est risk zones,which shows an effective assessment accuracy;(2) paddy,built-up,and residential areas concentrated in the higher and highest risk zones are more likely to be destroyed by flood disasters;(3) 200-225 refuges in the higher and highest risk zones account for around 50% of all refuges,which means that more refuges should be built in the higher and highest risk zones to meet the accommodation requirement;(4) three methods proved to be feasible and effective in evaluating flood disaster risk,among which FCA is more suitable for the study area than the two other methods.Weiguo Jiang Lei Deng Luyao Chen Jianjun Wu Jing Li 2009Progress in Natural Science:Materials International2009,19,10:35
3From concept to reality-A review to the primary test stand and its preliminary application in high energy density physics显示文摘Pulsed power technology,whereas the electrical energy stored in a relative long period is released in much shorter timescale,is an efficient method to create high energy density physics(HEDP)conditions in laboratory.Around the beginning of this century,China Academy of Engineering Physics(CAEP)began to build some experimental facilities for HEDP investigations,among which the Primary Test Stand(PTS),a multi-module pulsed power facility with a nominal current of 10 MA and a current rising time~90 ns,is an important achievement on the roadmap of the electro-magnetically driven inertial confinement fusion(ICF)researches.PTS is the first pulsed power facility beyond 10 TW in China.Therefore,all the technologies have to be demonstrated,and all the engineering issues have to be overcome.In this article,the research outline,key technologies and the preliminary HEDP experiments are reviewed.Prospects on HEDP research on PTS and pulsed power development for the next step are also discussed.Jianjun Deng Weiping Xie Shuping Feng Meng Wang Hongtao Li Shengyi Song Minghe Xia Ji Ce An He Qing Tian Yuanchao Gu Yongchao Guan Bin Wei Xianbin Huang Xiaodong Ren Jiakun Dan Jing Li Shaotong Zhou Hongchun Cai Siqun Zhang Kunlun Wang Qiang Xu Yujuan Wang Zhaohui Zhang Guilin Wang Shuai Guo Yi He Yiwei Zhou Zhanji Zhang Libing Yang Wenkang Zou 2016Matter and Radiation at Extremes2016,1,1:19
4Characteristics of the lunar samples returned by the Chang'E-5 mission显示文摘Forty-five years after the Apollo and Luna missions returned lunar samples,China's Chang’E-5(CE-5)mission collected new samples from the mid-latitude region in the northeastern Oceanus Procellarum of the Moon.Our study shows that 95%of CE-5 lunar soil sizes are found to be within the range of 1.40-9.35μm,while 95%of the soils by mass are within the size range of 4.84-432.27μm.The bulk density,true density and specific surface area of CE-5 soils are 1.2387 g/cm^(3),3.1952 g/cm^(3) and 0.56 m^(2)/g,respectively.Fragments from the CE-5 regolith are classified into igneous clasts(mostly basalt),agglutinate and glass.A few breccias were also found.The minerals and compositions of CE-5 soils are consistent with mare basalts and can be classified as low-Ti/low-Al/low-K type with lower rare-earth-element contents than materials rich in potassium,rare earth element and phosphorus.CE-5 soils have high FeO and low Mg index,which could represent a new class of basalt.Chunlai Li Hao Hu Meng-Fei Yang Zhao-Yu Pei Qin Zhou Xin Ren Bin Liu Dawei Liu Xingguo Zeng Guangliang Zhang Hongbo Zhang Jianjun Liu Qiong Wang Xiangjin Deng Caijin Xiao Yonggang Yao Dingshuai Xue Wei Zuo Yan Su Weibin Wen Ziyuan Ouyang 2022National Science Review2022,9,2:12
5Structural insights into a novel histone demethylase PHF8显示文摘histone methylation/demethylation 的动态规定在开发期间起一个重要作用。在人的植物 homeodomain (哲学博士) 的变化和截断摸蛋白质 8 (PHF8 ) 与 X 连接智力迟钝和面部异例被联系,例如一张长脸,宽广鼻音尖端,劈开 lip/cleft 腭和大手,然而,它的分子的功能和结构的基础仍然保持不清楚。这里,我们在高分辨率报导 PHF8 的催化核心的水晶结构与或没有伪 - ketoglutarate (伪 - KG ) 。生物化学、结构的研究表明 PHF8 是为甲醇化物 di 、单音甲醇化物的 histone H3 离氨酸 9,然而并非为 H3K9me3 特定的新奇 histone demethylase (H3K9me2/1 ) 。我们的分析也揭示人的 PHF8 怎么在 methylation 状态之间区别并且为 methylated H3K9 完成顺序特性。在里面 vitro demethylation 试金也证明在临床的病人观察的 F279S 异种不拥有 demethylation 活动,建议酶的活动的那损失为 PHF8 病人的致病是关键的。一起拿,这些结果将使位于联系 PHF8 的发展、神经病学的疾病下面的分子的机制清楚些。Lin Yu Yang wang Shuo Huang Jianjun Wang Zengqin Deng Qi Zhang Wei Wu Xingliang Zhang Zhao Liu Weimin Gong Zhongzhou Chen 2010Cell Research2010,20,2:11
6Modelling of dynamic recrystallization kinetics of 300M steel at high strain rates during hot deformation显示文摘The flow curves of 300M steel exhibit a transition from stress peak presence to stress peak absence as the strain rate increases. It is difficult to establish dynamic recrystallization(DRX) kinetics models suitable for strain rates where there are no stress peaks in the flow curves using the existing Avrami equation, and the optimal processing parameters for forging can be scarcely acquired.In this study, the high-temperature flow and DRX behavior of 300M steel are investigated by performing isothermal compression tests at temperatures between 1173–1423K with strain rates between 0.001–50 s-1. Distinct stress peaks can be found in the flow curves at low strain rates, and the average grain size decreases with the increase in the strain rate at the same temperature. The DRX mechanism is a discontinuous DRX, and the grain boundary migration plays an important role in the DRX process. In contrast, no stress peak is observed in the flow curves at high strain rates, and the average grain size no longer decreases with the strain rate increase at the same temperature. The DRX mechanism in this case is a continuous DRX. The demarcated strain rate is calculated based on the characteristics of the obtained flow curves and grain sizes. The recrystallization volume fraction model and prediction grain size model at high strain rates are established. In combination with the existing DRX kinetics models at low strain rates, the processing parameters can be optimized to produce components with excellent mechanical properties.GUO Peng DENG Lei WANG XinYun LI JianJun 2019Science China(Technological Sciences)2019,62,9:5
7High efficiency production of ginsenoside compound K by catalyzing ginsenoside Rb1 using snailase显示文摘The rare ginsenoside Compound K(C-K) is attracting more attention because of its good physiological activity and urgent need. There are many pathways to obtain ginsenoside C-K, including chemical and biological methods. Among these, the conversion of PPD-type ginsenosides by enzymatic hydrolysis is a trend due to its high efficiency and mild conditions. For effectively extracting from the other panaxadiol saponins, the conversion process for ginsenoside C-K was investigated using snailases in this study. The univariate experimental design and response surface methodology were used to determine the optimal hydrolysis conditions for the conversion of ginsenoside Rb1 into ginsenoside C-K by snailases. The optimum conditions were as follows: p H 5.12, temperature 51 °C, ratio of snailase/substrate 0.21, and reaction time 48 h. On the basis of these parameters, the addition of 1.0 mmol·L^(-1) ferric ion was found to significantly improve the enzymolysis of snailases for the first time. With the above conditions, the maximum conversion rate reached 89.7%, suggesting that the process can obviously increase the yield of ginsenoside C-K. The bioassay tests indicated that the ginsenoside C-K showed anti-tumor activity in a series of tumor cell lines. Based on these results, we can conclude that the process of rare ginsenoside CK production by enzymolysis with snailase is feasible, efficient, and suitable for the industrial production and application.Zhiguang Duan Chenhui Zhu Jingjing Shi Daidi Fan Jianjun Deng Rongzhan Fu Rong Huang Cuiying Fan 2018Chinese Journal of Chemical Engineering2018,26,7:5
8An Outbreak of Multidrug-Resistant Tuberculosis in a Secondary School --Hubei Province, 2019显示文摘What is already known about this topic?Multidrug-resistant tuberculosis(MDR-TB)is a type of tuberculosis with resistance to common treatments such as isoniazid and rifampicin.MDR-TB is a major global health challenge and needs to be controlled tightly through prevention measures,early diagnosis,and full treatment and management.What is added by this report?This outbreak was the first MDR-TB related public health emergency in Hubei Province.In total,five MDR-TB cases and nine clinically diagnosed cases were identified within one class in a secondary school.Students and teachers from other classes were monitored,but no other cases were found.What are the implications for public health practice?The implementation of TB prevention and control measures in schools is important to increase knowledge on TB and to raise awareness on protecting personal wellbeing.The Automatic Early Warning Information System alerted the local health department and allowed for a timely response to prevent further disease spread.Mengxian Zhang Tang Wang Shuangyi Hou Jianjun Ye Liping Zhou Zhong Zhang Zhiqiang Deng Qin Da Guoming Li Shiyue Li 2019China CDC weekly2019,1,5:5
9AFAP1-AS1: a rising star among oncogenic long non-coding RNAs显示文摘Long non-coding RNAs(lncRNAs)have become a hotspot in biomedical research.This interest reflects their extensive involvement in the regulation of the expression of other genes,and their influence on the occurrence and development of a variety of human diseases.Actin filament associated protein 1-Antisense RNA 1(AFAP1-AS1)is a recently discovered oncogenic lncRNA.It is highly expressed in a variety of solid tumors,and regulates the expression of downstream genes and signaling pathways through adsorption and competing microRNAs,or by the direct binding to other proteins.Ultimately,AFAP1-AS1 promotes proliferation,chemotherapy resistance,and resistance to apoptosis,maintains stemness,and enhances invasion and migration of tumor cells.This paper summarizes the research concerning AFAP1-AS1 in malignant tumors,including the clinical application prospects of AFAP1-AS1 as a potential molecular marker and therapeutic target of malignant tumors.We also discuss the limitations in the knowledge of AFAP1-AS1 and directions of further research.AFAP1-AS1 is expected to provide an example for studies of other lncRNA molecules.Fang Xiong Kunjie Zhu Su Deng Hongbin Huang Liting Yang Zhaojian Gong Lei Shi Yi He Yanyan Tang Qianjin Liao Jianjun Yu Xiaoling Li Yong Li Guiyuan Li Zhaoyang Zeng Wei Xiong Shanshan Zhang Can Guo 2021Science China(Life Sciences)2021,64,10:4
10不同白掌组合授粉结实和种子特性研究显示文摘为了解白掌属植物杂交授粉和结实特性,建立杂交选育群体,对白掌属13个种或品种植物进行了组合授粉杂交试验,实施杂交组合24个,9个杂交组合和S.floribundum开放自然授粉处理获得了果实和种子,培育了授粉后代群体;不同组合结果率为15.8%~100%,果实成熟需要50~108 d。各杂交组合每果实种子数为1~10.5个,种子具不同的大小、颜色和表面纹饰形态;不同组合的种子萌发率差异很大,从0.63%到84.67%,成苗率为0.63%~72.63%。结果表明,品种间容易杂交,而不同种间杂交结实率和正常发育种子率均较低。在泰勒×大花白掌和亮叶白掌×大花白掌两个组合中出现了黄化苗,比例分别为17.73%和16.1%。刘金梅 刘小飞 于波 DENG Zhanao CHEN Jianjun 廖飞雄 2015热带作物学报2015,36,7:4
11Construction of the Chinese Veteran Clinical Research (CVCR) Platform for the assessment of non-communicable diseases显示文摘Tan Jiping Li Nan Gao Jing Guo Yuhe Hu Wei Yang Jinsheng Yu Baocheng Yu Jianmin Du Wei Zhang Wenjun Cui Lianqi Wang Qingsong Xia Xiangnan Li Jianjun Zhou Peiyi Zhang Baohe Liu Zhiying Zhang Shaogang Sun Lanying Liu Nan Deng Ruixiang Dai Wenguang Yi Fang Chen Wenjun Zhang Yongqing Xue Shenwu Cui Bo Zhao Yiming Wang Luning 2014Chinese Medical Journal2014,,3:3
12Distribution of electric field and design of devices in GaN avalanche photodiodes显示文摘We have investigated the distribution of the electric field in p-i-n type and separate absorption and multiplication(SAM) type GaN avalanche photodiodes under different reverse bias values.We have also analyzed the influences of the parameters of each layer,including width and concentration,on the distribution of the electric field,especially on the breakdown voltage.It is found that a relatively high concentration of p-GaN(higher than 1×10 18 cm 3) and low carrier concentration of i-GaN(lower than 5×10 16 cm 3) are helpful to restrict the electric field and reduce the breakdown voltage.In a SAM(p-i-n-i-n) structure,a suitable choice should be made for the concentration and thickness of the intermediate n-GaN layer in order to decrease breakdown voltage and prevent the device from degenerating into a p-i-n structure.Finally,the optimized material parameters of each layer are proposed.WU LiangLiang ZHAO DeGang DENG Yi JIANG DeSheng ZHU JianJun WANG Hui LIU ZongShun ZHANG ShuMing ZHANG BaoShun YANG Hui 2012Science China(Physics,Mechanics & Astronomy)2012,55,4:2
13Improvement of tunnel compensated quantum well infrared detector显示文摘To reduce the difficulty of the epitaxy caused by multiple quantum well infrared photodetector(QWIP)with tunnel compensation structure,an improved structure is proposed.In the new structure,the superlattices are located between the tunnel junction and the barrier as the infrared absorption region,eliminating the effect of doping concentration on the well width in the original structure.Theoretical analysis and experimental verification of the new structure are carried out.The experimental sample is a two-cycle device,each cycle contains a tunnel junction,a superlattice infrared absorption region and a thick barrier.The photosurface of the detector is 200×200μm^2 and the light is optically coupled by 45°oblique incidence.The results show that the optimal operating voltage of the sample is-1.1 V,the dark current is 2.99×10^-8A,and the blackbody detectivity is1.352×10^8 cm·Hz^1/2·W^-1at 77 K.Our experiments show that the new structure can work normally.Chaohui Li Jun Deng Weiye Sun Leilei He Jianjun Li Jun Han Yanli Shi 2019Journal of Semiconductors2019,40,12:2
14Effect of Mineral Dusts on the Growth of Silicate Bacteria S35显示文摘以便在硅酸盐细菌 S35 上比较化学作文和灰尘的物理 properities ,六种矿物质灰尘的化学作文被分析了, pH 的变化珍视,葡萄糖( GLU ),电解质和 Mn , Si ,在灰尘前后的 Fe 与硅酸盐细菌 S35 反应了被测量了。SEM 分析被用来在在灰尘和细菌之间的反应期间学习细菌的形式和接口行动地位。结果证明这些矿物质灰尘在实验细菌上有不同效果。因此,硅酸盐细菌上的矿物质灰尘的效果与化学作文和灰尘的物理 properities 有关联,这被结束。DAI Qunwei DONG Faqin DENG Jianjun 2008Acta Geologica Sinica(English Edition)2008,82,5:2
15The interaction of DNA with phytoferritin during iron oxidation显示文摘Rui Yang Senpei Yang Xiayun Liao Jianjun Deng Guanghua Zhao 2014Food Chemistry2014,,:1
16Overview of pulsed power research at CAEP显示文摘Deng Jianjun Shi Jinshui Xie Weiping 2015IEEE Transactions On Plasma Science2015,43,8:1
17Effect of tannic acid on properties of soybean ( Glycine max ) seed ferritin: A model for interaction between naturally-occurring components in foodstuffs显示文摘Meiliang Li Xiaoling Jia Jingyun Yang Jianjun Deng Guanghua Zhao 2012Food Chemistry2012,,2:1
18The first strain of monkeypox isolated in the Chinese Mainland and preserved at the National Pathogen Resource Center of China显示文摘On September 16,2022,the first imported monkeypox case was reported in the Chinese Mainland.Laboratory tests including nucleic acid detection were carried out in Chongqing Nan’an Centre for Disease Control and Prevention and Chongqing Center for Disease Control and Prevention.After that,monkeypox virus was isolated by the Institute for Viral Disease Control and Prevention and preserved at the National Pathogen Resource Center on September 18,2022.The National Pathogen Resource Center shared the basic information of monkeypox virus strain,samples,biosafety,strain imaging,RT-PCR primers,and probes sequence timely to support the prevention and control of monkeypox epidemic and facilitate the scientific research on vaccine development,drug screening and evaluation of monkeypox virus in the future.Qiang Wei Baoying Huang Wei Huang Jingdong Song Li Mei Li Zhao Jing Yin Juan Zhang Wenling Wang Fei Ye Caiyun Li Liling Bai Yanhai Wang Yao Deng Bo Liu Mengnan Jiang Guizhen Wu Jun Han Hua Zhao Hua Ling Wenjie Tan Jianjun Liu 2022Infectious Medicine2022,1,4:1
19Physical mechanisms of inactivation of bacillus subtilis spores using cold atmospheric plasmas显示文摘Xutao Deng Jianjun Shi Michael G Kong 2006IEEE Trans on Plasma Sci2006,34,4:1
20Genetic relationships within Brassica rapa as inferred from AFLP fingerprints显示文摘Jianjun Zhao Xiaowu Wang Bo Deng Ping Lou Jian Wu Rifei Sun Zeyong Xu Jaap Vromans Maarten Koornneef Guusje Bonnema 2005Theoretical and Applied Genetics2005,,7:1
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