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| 1 | De novo characterization of the root transcriptome of a traditional Chinese medicinal plant Polygonum cuspidatum显示文摘Various active components have been extracted from the root of Polygonum cuspidatum.However,the genetic basis for their activity is virtually unknown.In this study,25600002 short reads (2.3 Gb) of P.cuspidatum root transcriptome were obtained via Illumina HiSeq 2000 sequencing.A total of 86418 unigenes were assembled de novo and annotated.Twelve,18,60 and 54 unigenes were respectively mapped to the mevalonic acid (MVA),methyl-D-erythritol 4-phosphate (MEP),shikimate and resveratrol biosynthesis pathways,suggesting that they are involved in the biosynthesis of pharmaceutically important anthraquinone and resveratrol.Eighteen potential UDP-glycosyltransferase unigenes were identified as the candidates most likely to be involved in the biosynthesis of glycosides of secondary metabolites.Identification of relevant genes could be important in eventually increasing the yields of the medicinally useful constituents of the P.cuspidatum root.From the previously published transcriptome data of 19 non-model plant taxa,1127 shared orthologs were identified and characterized.This information will be very useful for future functional,phylogenetic and evolutionary studies of these plants. | HAO DaCheng MA Pei MU Jun CHEN ShiLin XIAO PeiGen PENG Yong HUO Li XU LiJia SUN Chao | 2012 | Science China(Life Sciences)2012，55，5： | 36 |
| 2 | Research progress in the phytochemistry and biology of Ilex pharmaceutical resources显示文摘Ilex is a botanical source for various health-promoting and pharmaceutically active compounds that have been used in traditional Chinese medicine and food for thousands of years.Increasing interest in Ilex pharmaceutical and food resources has led to additional discoveries of terpenoids,saponins,polyphenols(especially flavonoids),glycosides,and many other compounds in various Ilex species,and to investigation of their chemotaxonomy,molecular phylogeny and pharmacol-ogy.In continuation of our studies on Ilex pharmacology and phylogeny,we review the phytochemistry,chemotaxonomy,molecular biology and phylogeny of Ilex species and their relevance to health-promotion and therapeutic efficacy.The similarity and dissimilarity between Ilex paraguariensis,the source plant of mate tea,and the source plants of large-leaved K udingcha(e.g.,Ilex kudingcha and Ilex latifolia)are discussed.It is essential to utilize emerging technologies in non-Camellia tea studies to promote the sustainable utilization of Ilex resources and the identification and development of novel compounds with potential health and clinical utility.Systems biology and '-omics'technologies will play an increasingly important role in pharmaceutical and food research on the bioactive compounds of Ilex species. | Dacheng Hao Xiaojie Gua Peigen Xiao Zhanguo Liang Lijia Xu Yong Peng | 2013 | Acta Pharmaceutica Sinica B2013，3，1： | 6 |
| 3 | Synthesis of novel β-amino ketones containing a p-aminobenzoic acid moiety and evaluation of their antidiabetic activities显示文摘The synthesis of two series of β-amino ketones containing a p-aminobenzoic acid moiety (TM-1 and TM-2) using a modified protocol of the Mannich reaction is reported. The molecular structures of a total of tweenty three new target compounds were characterized by 1H NMR, 13C NMR, ESI-MS and HR-MS. Subsequently, their antidiabetic activities were screened in vitro. The α-glucodase inhibition (α-GI) activity of compound 1e reached a remarkable level of 66.50%. The peroxisome proliferatoractivated receptor (PPAR) relative activation activities of six compounds are above 80%, and in particular 2i displays an unprecedentedly high PPAR of 130.91%. The structure-activity relationships of the compounds were established. 2i is also subject to further in-depth investigation. | TANG GuangXia YAN JuFang FAN Li XU Jin SONG XiaoLi JIANG Li LUO LingFei YANG DaCheng | 2013 | Science China Chemistry2013，56，4： | 5 |
| 4 | A Fast and Memory-Efficient Approach to NDN Name Lookup显示文摘For name-based routing/switching in NDN, the key challenges are to manage large-scale forwarding Tables, to lookup long names of variable lengths, and to deal with frequent updates. Hashing associated with proper length-detecting is a straightforward yet efficient solution. Binary search strategy can reduce the number of required hash detecting in the worst case. However, to assure the searching path correct in such a schema, either backtrack searching or redundantly storing some prefixes is required, leading to performance or memory issues as a result. In this paper, we make a deep study on the binary search, and propose a novel mechanism to ensure correct searching path without neither additional backtrack costs nor redundant memory consumptions. Along any binary search path, a bloom filter is employed at each branching point to verify whether a said prefix is present, instead of storing that prefix here. By this means, we can gain significantly optimization on memory efficiency, at the cost of bloom checking before each detecting. Our evaluation experiments on both real-world and randomly synthesized data sets demonstrate our superiorities | Dacheng He Dafang Zhang Ke Xu Kun Huang Yanbiao Li | 2017 | China Communications2017，14，10： | 4 |
| 5 | Thermally stable photoluminescence and long persistent luminescence of Ca3Ga4O9:Tb^3+/Zn^2+显示文摘A green long persistent luminescence(LPL) phosphor Ca_3 Ga_4 O_9:Tb^(3+)/Zn^(2+) was prepared. Ca_3 Ga_4 O_9 matrix exhibits blue self-activated LPL due to the creation of intrinsic traps. When Tb3+ is doped, the photoluminescence(PL) and LPL colors change from blue to green with their intensities significantly enhanced. The doping of Zn^(2+) evidently improves the PL and LPL performances of the Ca_3Ga_4O_9 matrix and Ca_3Ga_4O_9:Tb^(3+). The thermoluminescence(TL) spectra show that a successive trap distribution is formed by multiple intrinsic traps with different depths in the Ca_3 Ga_4 O_9 matrix, and the incorporation of Tb^(3+) and Zn^(2+) effectively increases the densities of these intrinsic traps. The existence of a successive trap distribution makes the Ca_3 Ga_4 O_9:Tb^(3+)/Zn^(2+) phosphor exhibit thermally stable PL and LPL, It is indicated that this phosphor shows great promise for the application such as high-temperature LPL phosphor. | Zhangwen Long Junhe Zhou Jianbei Qiu Qi Wang Dacheng Zhou Xuhui Xu Xue Yu Hao Wu Zhencai Li | 2018 | Journal of Rare Earths2018，36，7： | 4 |
| 6 | Transparent perovskite glass-ceramics for visual optical thermometry显示文摘Optical thermometers have aroused considerable attention in recent years,and the increasing demand of sensitivity for practical application encourages the investigation on developing innovative non-contact optical thermo metric materials with higher sensitivity and accuracy.Perovskite quantum dots(QDs)with excellent temperature-dependence optical properties,provide a feasible approach to realizing the detection of temperature change,however,their poor high temperature thermal stability and the facile realization to obtain the production remain a daunting challenge.Herein,growing Tb^(3+)-doped CsPbl_(3) QDs in situ in borosilicate glass is proposed,which ensures the phase stability,and high-efficiency florescence output of the all-inorganic perovskite as a temperature sensor.A higher absolute and relative temperature sensitivity(0.0398 K^(-1) and 7.12%/K,respectively),along with the visible color change from orange-red to yellow-green with the increase of temperature is accomplished.Notably,the repeatable florescence intensity of Tb^(3+)-doped CsPbl_(3) QDs under high temperature enables their temperature sensing application. | Qihua Yang Lei Zhao Zhaohui Fang Ze Yang Jiangyan Cao Yiyu Cai Dacheng Zhou Xue Yu Jianbei Qiu Xuhui Xu | 2021 | Journal of Rare Earths2021，39，6： | 3 |
| 7 | NiSe_(2)/Ni(OH)_(2) Heterojunction Composite through Epitaxial-like Strategy as High-Rate Battery-Type Electrode Material显示文摘Constructing heterojunction is a promising way to improve the charge transfer efficiency and can thus promote the electrochemical properties.Herein,a facile and effective epitaxial-like growth strategy is applied to NiSe2 nano-octahe-dra to fabricate the NiSe2-(100)/Ni(OH)2-(110)heterojunction.The heterojunction composite and Ni(OH)2(performing high electrochemical activity)is ideal high-rate battery-type supercapacitor electrode.The NiSe2/Ni(OH)2 electrode exhibits a high specific capacity of 909 C g^-1 at 1 A g^-1 and 597 C g^-1 at 20 A g^-1.The assembled asymmetric supercapacitor composed of the NiSe2/Ni(OH)2 cathode and p-phenylenediamine-functional reduced graphene oxide anode achieves an ultrahigh specific capacity of 303 C g^-1 at 1 A g^-1 and a superior energy density of 76.1 Wh kg^-1 at 906 W kg^-1,as well as an outstanding cycling stability of 82%retention for 8000 cycles at 10 A g^-1.To the best of our knowledge,this is the first example of NiSe2/Ni(OH)2 heterojunction exhibiting such remarkable supercapacitor performance.This work not only provides a promising candidate for next-generation energy storage device but also offers a possible universal strategy to fabricate metal selenides/metal hydroxides heterojunctions. | Hao Mei Zhaodi Huang Ben Xu Zhenyu Xiao Yingjie Mei Haobing Zhang Shiyu Zhang Dacheng Li Wenpei Kang Dao Feng Sun | 2020 | Nano-Micro Letters2020，12，5： | 3 |
| 8 | China Antihypertensive Trial in Acute Ischemic Stroke II (CATIS-2): rationale and design显示文摘Backgrounds Increased blood pressure(BP)for patients who had an acute ischaemic stroke is associated with poor functional outcome,however the optimal timing of antihypertensive therapy is unknown.Aims We aim to compare early antihypertensive treatment to delayed antihypertensive treatment for reducing the risk of composite major disability and mortality at 3 months in acute ischaemic stroke.Design The China Antihypertensive Trial in Acute Ischemic Stroke II(CATIS-2)trial is a multicentre,randomised,open-label,blinded-endpoints trial that will be conducted in 100 hospitals in China.The primary outcome is the composite of death and major disability(modified Rankin Scale score≥3)at 3 months of randomisation.Antihypertensive treatment will be received immediately after randomisation in the early treatment group,aimed at average systolic BP by 10%-20%reduction within the first 24 hours,and achieving an average BP level of<140/90 mm Hg within 5 days.Patients in the delayed treatment group will discontinue any antihypertension medications for the first 7 days of randomisation,and will receive antihypertensive therapy achieving a BP goal of<140/90 mm Hg after 7 days.Conclusion The CATIS-2 trial will be testing the hypotheses that early BP lowering leads to improved functional outcome without any other harms,and developing clinical guidelines of the BP management for patients who had an acute ischaemic stroke. | Liping Liu Yilong Wang Xuewei Xie Dacheng Liu Aili Wang Penglian Wang Suwen Shen Chongke Zhong Yufei Wei Tan Xu Yuesong Pan Yong Jiang Xia Meng David Wang Yonghong Zhang Jiang He Yongjun Wang | 2021 | Stroke & Vascular Neurology2021，6，2： | 3 |
| 9 | Synthesis of Spirostanol Saponins via Gold(Ⅰ)-Catalyzed Glycosylation in the Presence of Ga(Otf)3, In(Otf)3, or HOTf显示文摘Summary of main observation and conclusion An effective approach relying on a Lewis acid-or Brφnsted acid-assisted gold(Ⅰ)-catalyzed glycosylation has been reported in the synthesis of a panel of the representative natural spirostanol saponins,namely polyphyllin D (1),polyphyllin V (2),dioscin (3),formosanin C (4),and a derivative of polyphyllin D bearing a terminal azide group (5).This approach highlights the engagement of low Ioadings of Ph3AuPOTf (≤ 0.5mol%) in the presence of Ga(OTf)3,In(OTf)3,or HOTf (~10 mol%) as a co-catalyst,at practical reaction rates as an alternative to the conventional ~10 mol%Ioadings of the gold(Ⅰ) catalyst in the glycosylation.Polyphyllin D (1) was obtained in 41% overall yield over six steps compared to the maximum 30% yield in previous syntheses,where conventional donors and promoters were used.By exploiting a regioselective rhamnosylation,a 'one-pot' approach was adopted to assemble 1 and 5,thus further strengthening the efficiency of the gold(Ⅰ)-catalyzed glycosylation. | Teddy Stephen Ehianeta Dacheng Shen Peng Xu Biao Yu | 2019 | Chinese Journal of Chemistry2019，37，8： | 2 |
| 10 | Microscale heat transfer enhancement using thermal boundary layer redeveloping concept 显示文摘 | Xu J ingliang Gan Yunhua Zhang Dacheng | 2005 | International Journal of Heat and Mass Transfer2005，48，9： | 1 |
| 11 | Microscale heat transfer enhancement using thermal boundary layer redeveloping concept显示文摘 | Xu Jingliang Gan Yunhua Zhang Dacheng | | 0，，09： | 1 |
| 12 | Multiview vectorvalued manifold regularization for multilabel image classification显示文摘 | Luo Yong Tao Dacheng Xu Chang | 2013 | Neural Networks and Learning Systems2013，24，5： | 1 |
| 13 | Sub-40-fs high-power Yb:CALYO laser pumped by single-mode fiber laser显示文摘We report on the study of single-mode fiber-laser-pumped mode-locked Yb:CALYO lasers via using a passive saturable absorber and Kerr-lens mode-locking technique,respectively.Up to 3.1-W average power with 103-fs pulse duration is obtained from the passive mode-locking,and down to 36-fs pulse duration with more than 2-W average power is achieved by the pure Kerr-lens mode-locking,which is to the best of our knowledge,the highest average power from a reported sub-40-fs Yb-based solid-state oscillator. | Wenlong Tian Geyang Wang Dacheng Zhang Jiangfeng Zhu Zhaohua Wang Xiaodong Xu Jun Xu Zhiyi Wei | 2019 | High Power Laser Science and Engineering2019，7，4： | 1 |
| 14 | A NIR to NIR rechargeable long persistent luminescence phosphor Ca_(2)Ga_(2)GeO_(7):Yb^(3+),Tb^(3+)显示文摘Near infrared to near infrared(NIR-NIR)photo-stimulated persistent luminescence(PSPL)has shown excellent potential in high-resolution bioimaging for deep tissues.However,the PSPL in NIR-Ⅱregion(900-1700 nm)is still lacking.In this work,Ca_(2)Ga_(2)GeO_(7):Yb^(3+),Tb^(3+)(CGGYT)phosphor with unique lowdimensional crystal structure was synthesized by high-temperature solid-state reaction.Thanks to the carriers transferring from deep traps to shallow ones induced by low energy light,the 978 nm PSPL originating from ^(2)F_(5/2) to ^(2)F_(7/2) transition of Yb^(3+)induced by multimode stimulating(980 nm or WLED)is successfully realized after pre-excited by UV lamp.The NIR PSPL of the specimen can be repeatedly stimulated after placed in dark for 12 h.Moreover,the results indicate that codoping with Tb^(3+)can significantly enhance the NIR-ⅡPSPL owing to the quantum cutting persistent energy transfer(QC PET)from Tb^(3+)to Yb^(3+).Our study points to a new direction for the future development of multimode PSPL materials for bioimaging or multimode optical storage applications. | Junhe Zhou Zhangwen Long Jianbei Qiu Dacheng Zhou Jun'an Lai Xuhui Xu Songhan Hu Xizheng Li Qi Wang | 2021 | Journal of Rare Earths2021，39，12： | 1 |
| 15 | The PTEN tumor suppressor inhibits human airway smooth muscle cell migration显示文摘 | Haibing Lan Haohai Zhong Yang Gao Dunqiang Ren Lili Chen Dacheng Zhang Wenyan Lai Jian Xu Yaling Luo | 2010 | International Journal of Molecular Medicine2010，，6： | 1 |
| 16 | Binary fingerprint image thin- ning using template-based PCNN显示文摘 | Li Bailiang Xu Dacheng | 2007 | IEEE Transactions on Systems Man and Cybernetics2007，37，5： | 1 |
| 17 | Trends in heavy ion interaction with plasma显示文摘 | Yongtao Zhao Zhanghu Hu Rui Cheng Yuyu Wang Haibo Peng Alexander Golubev Xiaoan Zhang Xia Lu Dacheng Zhang Xianming Zhou Xing Wang Ge Xu Jieru Ren Yongfeng Li Yu Lei Yuanbo Sun Jiangtao Zhao Tieshan Wang Younian Wang Guoqing Xiao | 2012 | Laser and Particle Beams2012，，： | 1 |
| 18 | Explore the dominant factor in prime editing via a view of DNA processing显示文摘Prime editing is a revolutionary gene-editing method that is capable of introducing insertions,deletions and base substitutions into the genome.However,the editing efficiency of Prime Editor(PE)is limited by the DNA repair process.Here,we show that overexpression of the flap structure-specific endonuclease 1(FEN1)and the DNA ligase 1(LIG1)increases the efficiency of prime editing,which is similar to the dominant negative mutL homolog 1(MLH1dn).In addition,MLH1 is still the dominant factor over FEN1 and LIG1 in prime editing.Our results help to further understand the relationship of proteins involved in prime editing and envisage future directions for the development of PE. | Zhimeng Xu Dacheng Ma Houzhen Su Xiaodong Jia Yinqing Li Yinying Lu Zhen Xie | 2023 | Synthetic and Systems Biotechnology2023，8，3： | 0 |
| 19 | Potential risk of colonization of Bulinus globosus in the mainland of China under climate change显示文摘Background: Bulinus globosus,the main intermediate snail host of Schistosoma haematobium.The increased contacts between Africa and China could even lead to large-scale dissemination of B.globosus in China.Temperature is the key factor affecting fresh-water snail transmission.This study predicted potential risk of colonization of B.globosus in the mainland of China under climate change.Methods: We investigated minimum and maximum temperatures for B.globosus eggs,juveniles and adult snails kept under laboratory conditions to find the most suitable range by pinpointing the median effective temperatures(ET50).We also assessed the influence of temperature on spawning and estimated the accumulated temperature(AT).The average air temperatures between 1955 and 2019 in January and July,the coldest and hottest months in China,respectively,were collected from national meteorological monitoring stations and investigated in a geographic information system(GIS)using empirical Bayesian Kriging to evaluate the theoretical possibility for distribution of B.globosus in southern China based on temperature.Results: The effective minimum temperature(ET50min)for eggs,juveniles,adult snails and spawning were 8.5,7.0,7.0,14.9℃,respectively,with the corresponding maximum values(ET50max)of 36.6,40.5,40.2 and 38.1℃.The AT was calculated at 712.1±64.9℃·d.In 1955,the potential B.globosus distribution would have had a northern boundary stretching from the coastal areas of Guangdong Province and Guangxi Autonomous Region to southern Yunnan Province.Since then,this line has gradually moved northward.Conclusions: Annual regeneration of B.globosus can be supported by the current climate conditions in the mainland of China,and a gradual expansion trend from south to north is shown in the study from 2015 to 2019.Thus,there is a potential risk of colonization of B.globosus in the mainland of China under climate change. | Xinyao Wang Saleh Juma Wei Li Mchanga Suleman Mtumweni Ali Muhsin Jian He Mingzhen He Dacheng Xu Jianfeng Zhang Robert Bergquist Kun Yang | 2022 | Infectious Diseases of Poverty2022，11，3： | 0 |
| 20 | Test of RF Buncher Experiment at for Laser Cooling CSRe显示文摘 | Wen Weiqiang Ma Xinwen Zhang Dacheng Wang Zhishuai Meng Lingjie Zhu Xiaolong Liu Yong Mao Ruishi Zhao Tiecheng Yang Jiancheng Yang Xiaodong Yuan Youjin Xia Jiawen Xu Hushan Michael Bussmann | 2011 | IMP & HIRFL Annual Report2011，，1： | 0 |
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