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| 1 | Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration显示文摘房间通过 secreting 和释放蛋白质和泡与对方一起交流。许多房间能移居。在这研究,我们报导 migracytosis,为释放细胞的内容的房间迁居依赖者机制,和 migrasomes 的发现,调停的小囊的结构 migracytosis。当移居的房间移动,他们离开长管状的海滨,叫的收回纤维,在他们后面。大泡,包含众多的更小的泡,在收回纤维的尖端和交叉上成长。这些纤维,与主要房间身体连接泡,最后,裂缝,和泡被释放直到细胞外的空间或直接由包围房间收起。因为这些泡的形成是迁居依赖者,我们把他们称为 “ migrasomes”。我们也发现 cytosolic 内容能被搬运进 migrasomes 并且通过 migrasomes 免除了房间。我们把这迁居依赖者版本机制称为 “ migracytosis”。 | Liang Ma Ying Li Junya Peng Danni Wu Xiaoxin Zhao Yitong Cui Lilian Chen Xiaojun Yan Yanan Du Li Yu | 2015 | Cell Research2015，25，1： | 21 |
| 2 | Reduced Macular Vascular Density in Myopic Eyes显示文摘 | Hua Fan Hao-Yu Chen Hong-Jie Ma Zheng Chang Hai-Quan Yin Danny Siu-Chun Ng Carol Y Cheung Shan Hu Xiang Xiang Shi-Bo Tang Shuang-Nong Li | 2017 | Chinese Medical Journal2017，，4： | 17 |
| 3 | Pairing of integrins with ECM proteins determines migrasome formation显示文摘 | Danni Wu Yue Xu Tianlun Ding Yan Zu Chun Yang Li Yu | 2017 | Cell Research2017，27，11： | 14 |
| 4 | Satellite virtual atomic clock with pseudorange difference function显示文摘Satellite atomic clocks are the basis of GPS for the control of time and frequency of navigation signals. In the Chinese Area Positioning System (CAPS), a satellite navigation system without the satellite atomic clocks onboard is successfully developed. Thus, the method of time synchronization based on satellite atomic clocks in GPS is not suitable. Satellite virtual atomic clocks are used to implement satellite navigation. With the satellite virtual atomic clocks, the time at which the signals are transmitted from the ground can be delayed into the time that the signals are transmitted from the satellites and the pseudorange measuring can be fulfilled as in GPS. Satellite virtual atomic clocks can implement the navigation, make a pseudorange difference, remove the ephemeris error, and improve the accuracy of navigation positioning. They not only provide a navigation system without satellite clocks, but also a navigation system with pseudorange difference. | LI XiaoHui WU HaiTao BIAN YuJing WANG DanNi | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，3： | 11 |
| 5 | Cross-talk between NMDA and GABA_A receptors in cultured neurons of the rat inferior colliculus显示文摘Neuronal ion channels of different types often do not function independently but will inhibit or potentiate the activity of other types of channels,a process called cross-talk.The N-methyl-D-aspartate receptor (NMDA receptor) and the γ-aminobutyric acid type A receptor (GABAA receptor) are important excitatory and inhibitory receptors in the central nervous system,respectively.Currently,cross-talk between the NMDA receptor and the GABAA receptor,particularly in the central auditory system,is not well understood.In the present study,we investigated functional interactions between the NMDA receptor and the GABAA receptor using whole-cell patch-clamp techniques in cultured neurons from the inferior colliculus,which is an important nucleus in the central auditory system.We found that the currents induced by aspartate at 100 μmol L-1 were suppressed by the pre-perfusion of GABA at 100 μmol L-1,indicating cross-inhibition of NMDA receptors by activation of GABAA receptors.Moreover,we found that the currents induced by GABA at 100 μmol L-1 (IGABA) were not suppressed by the pre-perfusion of 100 μmol L-1 aspartate,but those induced by GABA at 3 μmol L-1 were suppressed,indicating concentration-dependent cross-inhibition of GABAA receptors by activation of NMDA receptors.In addition,inhibition of IGABA by aspartate was not affected by blockade of voltage-dependent Ca2+ channels with CdCl2 in a solution that contained Ca2+,however,CdCl2 effectively attenuated the inhibition of IGABA by aspartate when it was perfused in a solution that contained Ba2+ instead of Ca2+ or a solution that contained Ca2+ and 10 mmol L-1 BAPTA,a membrane-permeable Ca2+ chelator,suggesting that this inhibition is mediated by Ca2+ influx through NMDA receptors,rather than voltage-dependent Ca2+ channels.Finally,KN-62,a potent inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII),reduced the inhibition of IGABA by aspartate,indicating the involvement of CaMKII in this cross-inhibition.Our study demonstrates a functional interaction between NMDA and GABAA receptors in the inferior colliculus of rats.The presence of cross-talk between these receptors suggests that the mechanisms underlying information processing in the central auditory system may be more complex than previously believed. | CONG DanNi TANG ZhengQuan LI LongZhu HUANG YiNa WANG Jun CHEN Lin | 2011 | Science China(Life Sciences)2011，54，6： | 9 |
| 6 | Time synchronization and carrier frequency control of CAPS navigation signals generated on the ground显示文摘The Chinese Area Positioning System (CAPS) works without atomic clocks on the satellite, and the CAPS navigation signals transmitted on the ground may achieve the same effect as that with high-performance atomic clocks on the satellite. The primary means of achieving that effect is through the time synchronization and carrier frequency control of the CAPS navigation signals generated on the ground. In this paper the synchronization requirements of different time signals are analyzed by the formation of navigation signals, and the theories and methods of the time synchronization of the CAPS navigation signals generated on the ground are also introduced. According to the conditions of the high-precision satellite velocitymeasurement signal source, the carrier frequency and its chains of the navigation signals are constructed. CAPS velocity measurement is realized by the expected deviation of real time control to the carrier frequency, and the precision degree of this method is also analyzed. The experimental results show that the time synchronization precision of CAPS generating signals is about 0.3 ns and the precision of the velocity measurement signal source is about 4 cm/s. This proves that the theories and methods of the generating time synchronization and carrier frequency control are workable. | WU HaiTao BIAN YuJing LU XiaoChun LI XiaoHui WANG DanNi | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，3： | 8 |
| 7 | Mechanistic-empirical pavement design guide(MEPDG):a bird's-eye view显示文摘Past editions of the American Association of State Highway and Transportation Officials(AASHTO) Guide for Design of Pavement Structures have served well for several decades;nevertheless,many serious limitations exist for their continued use as the nation's primary pavement design procedures.Researchers are now incorporating the latest advances in pavement design into the new Mechanistic-Empirical Pavement Design Guide(MEPDG),developed under the National Cooperative Highway Research Program(NCHRP) 1-37A project and adopted and published by AASHTO.The MEPDG procedure offers several dramatic improvements over the current pavement design guide and presents a new paradigm in the way pavement design is performed.However,MEPDG is substantially more complex than the AASHTO Design Guide by considering the input parameters that influence pavement performance,including traffic,climate,pavement structure and material properties,and applying the principles of engineering mechanics to predict critical pavement responses.It requires significantly more input from the designer.Some of the required data are either not tracked previously or are stored in locations not familiar to designers,and many data sets need to be preprocessed for use in the MEPDG.As a result,tremendous research work has been conducted and still more challenges need to be tackled both in federal and state levels for the full implementation of MEPDG.This paper,for the first time,provides a comprehensive bird's eye view for the MEPDG procedure,including the evolvement of the design methodology,an overview of the design philosophy and its components,the research conducted during the development,improvement,and implementation phases,and the challenges remained and future developments directions.It is anticipated that the efforts in this paper aid in enhancing the mechanistic-empirical based pavement design for future continuous improvement to keep up with changes in trucking,materials,construction,design concepts,computers,and so on. | Qiang LI Danny X. XIAO Kelvin C. P. WANG Kevin D. HALL Yanjun QIU | 2011 | Journal of Modern Transportation2011，19，2： | 4 |
| 8 | Publisher's note to“Texture engineering of mono-crystalline silicon via alcohol-free alkali solution for efficient PERC solar cells”[J.Energy Chem.71(2022)104-107显示文摘The publisher regrets that the page range of this paper was incorrect due to production error,and we added al-a5 after page 107 to the pdf version to correct this mistake. | Danni Zhang Jiawang Chen Rui Jia Zhibo Gao Ke Tao Longjie Wang Huayun Ge Xinpu Li Xing Li | 2022 | Journal of Energy Chemistry2022，31，8： | 3 |
| 9 | A single-cell transcriptome of mesenchymal stromal cells to fabricate bioactive hydroxyapatite materials for bone regeneration显示文摘The osteogenic microenvironment of bone-repairing materials plays a key role in accelerating bone regeneration but remains incompletely defined,which significantly limits the application of such bioactive materials.Here,the transcriptional landscapes of different osteogenic microenvironments,including three-dimensional(3D)hydroxyapatite(HA)scaffolds and osteogenic medium(OM),for mesenchymal stromal cells(MSCs)in vitro were mapped at single-cell resolution.Our findings suggested that an osteogenic process reminiscent of endochondral ossification occurred in HA scaffolds through sequential activation of osteogenic-related signaling pathways,along with inflammation and angiogenesis,but inhibition of adipogenesis and fibrosis.Moreover,we revealed the mechanism during OM-mediated osteogenesis involves the ZBTB16 and WNT signaling pathways.Heterogeneity of MSCs was also demonstrated.In vitro ossification of LRRC75A+MSCs was shown to have better utilization of WNT-related ossification process,and PCDH10+MSCs with superiority in hydroxyapatite-related osteogenic process.These findings provided further understanding of the cellular activity modulated by OM conditions and HA scaffolds,providing new insights for the improvement of osteogenic biomaterials.This atlas provides a blueprint for research on MSC heterogeneity and the osteogenic microenvironment of HA scaffolds and a database reference for the application of bioactive materials for bone regeneration. | Peng Guo Xizhe Liu Penghui Zhang Zhongyuan He Zhen Li Mauro Alini RGeoff Richards Sibylle Grad Martin J.Stoddart Guangqian Zhou Xuenong Zou Danny Chan Wei Tian Dafu Chen Manman Gao Zhiyu Zhou Shaoyu Liu | 2022 | Bioactive Materials2022，7，3： | 3 |
| 10 | Removal of trimethoprim and sulfamethoxazole in artificial composite soil treatment systems and diversity of microbial communities显示文摘Four artificial composite soil treatment systems(ACSTs)fed with reclaimed water containing trimethoprim(TMP)and sulfamethoxazole(SMX)were constructed to investigate SMX and TMP biodegradation efficiency,ammonia and nitrite removal conditions and the microbial community within ACST layers.Results showed SMX and TMP removal rates could reach 80% and 95%,respectively,and removal rates of ammonia and nitrite could reach 80% and 90%,respectively,in ACSTs.The MiSeq sequencing results showed that microbial community structures of the ACSTs were similar.The dominant microbial community in the adsorption and biodegradation layers of the ACSTs contained Proteobacteria,Chloroflexi,Acidobacteria,Firmicutes,Actinobacteria and Nitrospirae.Firmicutes and Proteobacteria were considerably dominant in the ACST biodegradation layers.The entire experimental results indicated that Nitrosomonadaceae_uncultured,Nitrospira and Bacillus were associated with nitrification processes,while Bacillus and Lactococcus were associated with SMX and TMP removal processes.The findings suggest that ACSTs are appropriate for engineering applications. | Qinqin Liu Miao Li Rui Liu Quan Zhang Di Wu Danni Zhu Xuhui Shen Chuanping Feng Fawang Zhang Xiang Liu | 2019 | Frontiers of Environmental Science & Engineering2019，13，2： | 2 |
| 11 | Magnetic resonance (MR) safety and compatibility of a novel iron bioresorbable scaffold显示文摘Fully bioresorbable scaffolds have been designed to overcome the limitations of traditional drug-eluting stents(DESs),which permanently cage the native vessel wall and pose possible complications.The ultrathin-strut designed sirolimus-eluting iron bioresorbable coronary scaffold system(IBS)shows comparable mechanical properties to traditional DESs and exhibits an adaptive degradation profile during target vessel healing,which makes it a promising candidate in all-comers patient population.For implanted medical devices,magnetic resonance(MR)imaging properties,including MR safety and compatibility,should be evaluated before its clinical use,especially for devices with intrinsic ferromagnetism.In this study,MR safety and compatibility of the IBS scaffold were evaluated based on a series of well-designed in-vitro,ex-vivo and in-vivo experiments,considering possible risks,including scaffold movement,over-heating,image artifact,and possible vessel injury,under typical MR condition.Traditional ASTM standards for MR safety and compatibility evaluation of intravascular devices were referred,but not only limited to that.The unique time-relevant MR properties of bioresorbable scaffolds were also discussed.Possible forces imposed on the scaffold during MR scanning and MR image artifacts gradually decreased along with scaffold degradation/absorption.Rigorous experiments designed based on a scientifically based rationale revealed that the IBS scaffold is MR conditional,though not MR compatible before complete absorption.The methodology used in the present study can give insight into the MR evaluation of magnetic scaffolds(bioresorbable)or stents(permanent). | Dong Bian Li Qin Wenjiao Lin Danni Shen Haiping Qi Xiaoli Shi Gui Zhang Hongwei Liu Han Yang Jin Wang Deyuan Zhang Yufeng Zheng | 2020 | Bioactive Materials2020，5，2： | 2 |
| 12 | Ultrasmall Ga-ICG nanoparticles based gallium ion/photodynamic synergistic therapy to eradicate biofilms and against drug-resistant bacterial liver abscess显示文摘Pyogenic liver abscess and keratitis are aggressive bacterial infections and the treatment has failed to eradicate bacteria in infectious sites completely owing to the currently severe drug resistance to existing antibiotics.Here,we report a simple and efficient one-step development of ultrasmall non-antibiotic nanoparticles(ICG-Ga NPs)containing clinically approved gallium(Ⅲ)(Ga^(3+))and liver targeting indocyanine green(ICG)molecules to eradicate multi-drug resistant(MDR)bacteria thought the synergetic effect of photodynamic therapy and iron metabolism blocking.The ICG-Ga NPs induced photodynamic effect could destroy the bacterial membrane,further boost the endocytosis of Ga^(3+),then replace iron in bacteria cells to disrupt bacterial iron metabolism,and demonstrate the synergetic bacterial killing and biofilm disrupting effects.The ICG-Ga NPs show an excellent therapeutic effect against extended spectrumβ-lactamases Escherichia coli(ESBL E.coli)and significantly improve treatment outcomes in infected liver abscess and keratitis.Meanwhile,the ultrasmall size of ICG-Ga NPs could be cleared rapid via renal clearance route,guaranteeing the biocompatibility.The protective effect and good biocompatibility of ICG-Ga NPs will facilitate clinical treatment of bacteria infected diseases and enable the development of next-generation non-antibiotic antibacterial agents. | Tingting Xie Yuchen Qi Yangyang Li Feilu Zhang Wanlin Li Danni Zhong Zhe Tang Min Zhou | 2021 | Bioactive Materials2021，6，11： | 2 |
| 13 | In-situ polymerized cross-linked binder for cathode in lithium-sulfur batteries显示文摘Volume expansion and polysulfide shuttle effect are the main barriers for the commercialization of lithium-sulfur(Li-S) battery.In this work,we in-situ polymerized a cross-linked binder in sulfur cathode to solve the aforementioned problems using a facile method under mild conditions.Polycarbonate diol(PCDL),triethanolamine(TEA) and hexamethylene diisocyanate(HDI) were chosen as precursors to prepare the cross-linked binder.The in-situ polymerized binder(PTH) builds a strong network in sulfur cathode,which could restrain the volume expansion of sulfu r.Moreover,by adopting functional groups of oxygen atoms and nitrogen atoms,the binder could effectively facilitate transportation of Li-ion and adsorb polysulfide chemically.The Li-S battery with bare sulfur and carbon/sulfur composite cathodes and cross-linked PTH binder displays much better electrochemical performance than that of the battery with PVDF.The PTH-bare S cathode with a mass loading of 5.97 mg/cm^2 could deliver a capacity of 733.3 mAh/g at 0.2 C,and remained 585.5 mAh/g after 100 cycles.This in-situ polymerized binder is proved to be quite effective on restraining the volume expansion and suppressing polysulfide shuttle effect,then improving the electrochemical performance of Li-S battery. | Heng Ye Danni Lei Lu Shen Bin Ni Baohua Li Feiyu Kang Yan-Bing He | 2020 | Chinese Chemical Letters2020，31，2： | 2 |
| 14 | A Review of the Design and Architecture of Starch-Based Dietary Foods显示文摘Carbohydrates,which are mostly present in sugar,starch,and fiber,are one of the main ingredients of food and the primary source of energy in the human diet.Among these three main sources,starch stands out as one of the most abundant reserves of carbohydrates.Investigating starch would not only enhance our understanding of the functionality of starch in the human body but also aid in the design of novel starch-based dietary foods.The present review first provides a state-of-the-art understanding of the various classifications of dietary starches,including rapidly digesting starch(RDS),slowly digesting starch(SDS),and resistant starch(RS).Moreover,both the in vivo and in vitro determination methods of the digestibility of starch-based dietary foods are discussed.Based on the current understanding,present research strategies to design novel starch-based dietary foods through either the direct addition of modified starch or the alteration of processing conditions are highlighted.Furthermore,certain perspectives related to the future research directions of starch-based foods are also included. | Yuxiang Bai Xiaoxiao Li Hangyan Ji Yu Wang Danni Zheng Yanli Wang Zhengyu Jin | 2021 | Engineering2021，7，5： | 2 |
| 15 | Preparation of basic lead oxide from spent lead acid battery paste via chemical conversion显示文摘 | Xinfeng Zhu Lei Li Xiaojuan Sun Danni Yang Linxia Gao Jianwen Liu R. Vasant Kumar Jiakuan Yang | 2012 | Hydrometallurgy2012，，： | 2 |
| 16 | An ultrathin and continuous Li_4Ti_5O_(12) coated carbon nanofiber interlayer for high rate lithium sulfur battery显示文摘Severe capacity fading and poor high rate performance of lithium sulfur(Li–S) battery caused by 'shuttle effect' and low conductivity of sulfur hampers its further developments and applications. Li_4Ti_5O_(12) (LTO)possesses high lithium ion conductivity, and it is also can be used as an active adsorbent for polysulfide. Herein, fine LTO particle coated carbon nanofibers(CNF) were prepared and a conductive network both for electron and lithium ion was built, which can greatly promote the electrochemical conversion of polysulfide and improve the rate performance of Li–S batteries. Meanwhile, a quantity of adsorption sites is constructed by defects of the surface of LTO-CNF membrane to effectively immobilize polysulfide. The multifunctional LTO-CNF interlayer could impede the shuttle effect and enhance comprehensive electrochemical performance of Li–S batteries, especially high rate performance. With such LTO-CNF interlayer,the Li–S battery presents a specific capacity of 641.9 mAh/g at 5 C rate. After 400 cycles at 1 C, a capacity of 618.0 mAh/g is retained. This work provides a feasible strategy to achieve high performance of Li–S battery for practical utilization. | Decheng An Lu Shen Danni Lei Lehong Wang Heng Ye Baohua Li Feiyu Kang Yan-Bing He | 2019 | Journal of Energy Chemistry2019，28，4： | 2 |
| 17 | An analysis of measured and simulated daylight illuminance and lighting savings in a daylit corridor 显示文摘 | Danny HW Li Ernest KW Tsang | 2005 | Building and Environment2005，40，： | 1 |
| 18 | Electricity Consumption Characteristics in Shopping Malls in Subtropical Climates显示文摘 | Joseph C Lam Danny H W Li | 2003 | Energy Conversion & Management2003，，13： | 1 |
| 19 | Correlation between global solar radiation and its direct and diffuse components显示文摘 | Joseph C Lam Danny H W Li | 1996 | Building and Environment1996，31，： | 1 |
| 20 | An analysis of electricity end use in air-conditioned office buildings in Hong Kong显示文摘 | LAM C JOSEPH LI H W DANNY CHEUNG S O | 2003 | Building and Environment2003，38，3： | 1 |
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