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| 1 | Microscopic colitis:A large retrospective analysis from a health maintenance organization experience显示文摘AIM:To examine the demographic data on a large multi-ethnic population of patients with microscopic colitis (MC) in Southern California and to determine the association of MC with inflammatory bowel disease (IBD) and colorectal cancer.METHODS: All patients diagnosed with MC by colonic biopsy from 1996-2005 were identified utilizing a pathology database. All biopsies were reviewed by experienced pathologists utilizing standard histologic criteria. Patients' medical records were reviewed and data regarding patient age, co-morbidities, sex, ethnicity, and medications were analyzed. An age-and sexmatched standard control group was also generated. Chi-square test was used to evaluate the associations of co-morbidities between lymphocytic colitis (LC), collagenous colitis (CC) and the control group.RESULTS: A total of 547 cases of MC were identif ied,376 patients with LC and 171 patients with CC. The female/male ratio was 3:1 in CC and 2.7:1 in LC patients. Celiac disease (P<0.001), irritable bowel syndrome (IBS) (P<0.001), and thyroid diseases (P<0.001) were found to have a higher occurrence in MC compared to the control group. No statistical differences in the occurrence of colorectal cancer, diabetes and IBD were found between the MC group and the control group.CONCLUSION: This is the largest group of patients with MC known to the authors that has been studied to date. Conditions such as celiac disease, IBS, and thyroid diseases were found to be related to MC. Furthermore, neither an increased risk of colorectal cancer nor IBD was associated with MC in this study. | Kevin T Kao Benito A Pedraza Amy C McClune David A Rios Yi-Qiong Mao Robert H Zuch Michael H Kanter Sony Wirio Chris N Conteas | 2009 | World Journal of Gastroenterology2009，15，25： | 5 |
| 2 | Sofosbuvir with pegylated interferon alfa-2a and ribavirin for treatment-naive patients with hepatitis C genotype-1 infection (ATOMIC): an open-label, randomised, multicentre phase 2 trial显示文摘 | Kris V Kowdley Eric Lawitz Israel Crespo Tarek Hassanein Mitchell N Davis Michael DeMicco David E Bernstein Nezam Afdhal John M Vierling Stuart C Gordon Jane K Anderson Robert H Hyland Hadas Dvory-Sobol Di An Robert G Hindes Efsevia Albanis William T Symo | 2013 | The Lancet2013，，9883： | 3 |
| 3 | Adipocyte iron regulates adiponectin and insulin sensitivity显示文摘 | Gabrielsen J Scott Gao Yan Simcox Judith A Huang Jingyu Thorup David Jones Deborah Cooksey Robert C Gabrielsen David Adams Ted D Hunt Steven C Hopkins Paul N Cefalu William T McClain Donald A | 2012 | EN2012，，10： | 2 |
| 4 | Transparent conducting Nnc oxide thin films doped with aluminum and molybdenum显示文摘 | JOEL N D TIMOTHY A G DAVID M W TERESA M B MATTHEW Y BOBBY T TIMOTHY J C | 2007 | Journal V-acuum Society Technology2007，25，4： | 1 |
| 5 | Enterprise Application Integration in the Electronic Commerce World显示文摘 | Erasala N David C Rajkumar T | 2003 | Computer Standards & Interfaces2003，25，1： | 1 |
| 6 | Capacity scaling in MIMO wireless systems under correlated fading 显示文摘 | Chuah C-N David N C T Kahn J M | 2002 | IEEE Transactions On Information Theory2002，48，3： | 1 |
| 7 | A population-based study of the drug interaction between proton pump inhibitors and clopidogrel显示文摘 | Juurlink David N Gomes Tara Ko Dennis T Szmitko Paul E Austin Peter C Tu Jack V Henry David A Kopp Alex Mamdani Muhammad M | 2009 | Canadian Medical Association. Journal2009，，7： | 1 |
| 8 | Cooperativediversity in wireless networks: efficient protocols and outagebehavior显示文摘 | LANEMAN J DAVID N C WORNELL T G | 2004 | IEEE Transaction on Information Theory2004，50，12： | 1 |
| 9 | Sulfur assimilation and glutathione metabolism under cadmium stress in yeast, protists and plants显示文摘 | David M C Herminia L T Andrea H N | 2005 | Ferns Microbiology Reviews2005，29，： | 1 |
| 10 | Grading Ovarian Serous Carcinoma Using a Two-Tier System显示文摘 | Anais Malpica Michael T Deavers Karen Lu Diane C Bodurka Edward N Atkinson David M Gershenson Elvio G Silva | 2004 | The American Journal of Surgical Pathology2004，，4： | 1 |
| 11 | Concerted assembly and cloning of multiple DNA segments using in vitro sitespecific recombination:functional analysis of multisegment expression clones显示文摘 | David L C Steven A T Devon R N B | 2004 | Genome Research2004，，14： | 1 |
| 12 | Myogenin and MEF2 function synergistically to activate the MRF4 promoter during myogenesis 显示文摘 | PADMAVATHY S N DAVID C L ROBERT Q T | 1995 | Molecular and Cellular Biology1995，15，5： | 1 |
| 13 | Impact of the flexible character of MIL-88 ironrlll) dicarboxylates on the adsorption of n-alkanes显示文摘 | Ramsahye N A Trung T K Scott L Nouar F Devic T Horcajada P Magnier E David 0 Serre C Trens P | 2013 | Chemistry of Materials2013，25，3： | 1 |
| 14 | Gland cells in Hydra: Cell cycle kinetics and development显示文摘 | Schmidt T David C N | 1986 | J Cell Sci1986，85，： | 1 |
| 15 | Production of α-1,3-galactosyltransferase knockout Pigs by nuclear transfer cloning显示文摘 | Donna K S Kwang W P Hee T C Julia L G Gi S I Melissa S Aaron B August R Billy N D Clifton N M David B C Robert J H Randall S P | 2002 | Science2002，295，5557： | 1 |
| 16 | Cooperative Diversity in Wireless Networks: Efficient Protocols and Outage Behavior显示文摘 | NICHOLAS L J DAVID N C T GREGORY W W | 2004 | IEEE IEEE Transactions on Information Theory2004，50，12： | 1 |
| 17 | Precise Position Control of Tubular Linear Motors with Neural Networks and Composite Learning显示文摘 | David N Francesco C Biagio T | | 0，，18： | 1 |
| 18 | Caspase-dependent alterations of Ca2+ signaling in the induction of apoptosis by hepatitis B virus X protein显示文摘 | MOUNIA C DAVIDE F PIERLUIGI N e t al | 2003 | J Biol Chem2003，278，31： | 1 |
| 19 | Mobility increases the capacity of ad hoc wireless networks 显示文摘 | Grossglauser M David N C T | 2002 | IEEE/ACM Trans on Networking2002，10，4： | 1 |
| 20 | Sofosbuvir with pegylated interferon alfa-2a and ribavirin for treatment-naive patients with hepatitis C genotype-1 infection (ATOMIC): an open-label, randomised, multicentre phase 2 trial显示文摘 | Kris V Kowdley Eric Lawitz Israel Crespo Tarek Hassanein Mitchell N Davis Michael DeMicco David E Bernstein Nezam Afdhal John M Vierling Stuart C Gordon Jane K Anderson Robert H Hyland Hadas Dvory-Sobol Di An Robert G Hindes Efsevia Albanis William T Symo | 2013 | The Lancet2013，，9883： | 1 |
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