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| 1 | Inflammatory bowel disease requires the interplay between innate and adaptive immune signals显示文摘煽动性的碗疾病(IBD ) 是一种类型 1 个 T 助手房间(Th1 ) 调停了自体免疫的疾病。各种各样的研究表明了环境病原体也在这疾病的开始和前进起一个重要作用。有趣地, IBD 的致病被显示了与氮的氧化物有关(没有) 免除了天生的有免疫力的房间。尽管不被知道对内脏 epithelia 高度有毒,没有生产的规定有很小的信息,在 IBD 的病原学的一个主要问题是 Th1 房间和病原体怎么在 IBD 的正式就职交往。在现在的学习,我们集中于我们显示出的号码的规定巨噬细胞要求两 interferon-gamma (IFN-gamma ) ,这调停了并且为生产的调停 TLR4 的信号没有,它在肠并且随后引起发炎 IBD。因此, IBD 是天生的有免疫力的信号的一致行动的结果,例如到 TLR-4,和适应有免疫力的信号的 LPS 的绑定,例如 Th1 房间生产的 IFN-gamma。 | Dayna Shi Jyoti Das Gobardhan Das | 2006 | Cell Research2006，16，1： | 8 |
| 2 | Diabetes mellitus increases risk for colorectal adenomas in younger patients显示文摘AIM:To determine if diabetes mellitus(DM)is associated with increased risk of colorectal adenomas in younger subjects.METHODS:This was a retrospective cohort study of375 patients undergoing index colonoscopy at a single tertiary care center in the United States.Three cohorts of patients matched for exam date and gender were compared:(1)ages 40-49 years with DM;(2)ages40-49 years without DM;and(3)ages 50-59 years without DM.Data collected included demographics,co-morbidities,colonoscopy and pathology results.Adenoma detection rates(ADR)were calculated and compared.Conditional logistic regression analysis was performed to determine the association between each cohort and ADR.RESULTS:One hundred and twenty-five patients ages40-49 with DM met study eligibility criteria.Patients in the other two cohorts were randomly selected,match-ing for date of exam and gender.ADR was 14.4%in those ages 40-49 years without DM,30.4%in those ages 40-49 years with DM,and 32.0%in those ages50-59 years without DM.Compared to those ages40-49 years without DM,ADR was higher in those ages40-49 years with DM(OR=3.1;95%CI:1.5-6.4;P=0.002)and those ages 50-59 years without DM(OR=2.9;95%CI:1.5-5.6;P=0.002).There was no difference between the ADR in those ages 40-49 years with DM and those ages 50-59 years without DM(P=0.83).CONCLUSION:DM was associated with higher risk of colorectal adenomas in patients ages 40-49 years.These subjects harbored as many adenomas as those at the standard screening age of 50-59 years without DM. | Hongha T Vu Nneka Ufere Yan Yan Jean S Wang Dayna S Early Jill E Elwing | 2014 | World Journal of Gastroenterology2014，20，22： | 5 |
| 3 | Perinatal Listeria monocytogenes susceptibility despite preconceptual priming and maintenance of pathogen-specific CD8^+ T cells during pregnancy显示文摘Listeria monocytogenes (Lm ) 为发展中的胎儿在怀孕和疾病的后果期间是有为全身的母亲的感染的唯一的倾向的一个细胞内部的细菌。给与出生前的 Lm 感染联系的高死亡,为在怀孕的极其脆弱的经期期间扩充保护的免疫的策略着急地被需要。此处,保护由在对随后的剧毒的 Lm 出生前的感染的怀孕被评估以前,管理的稀释 Lm 交谈了。因为显著地更多的细菌从母亲的纸巾被恢复,我们证明对在非怀孕的老鼠的第二等的 Lm 感染的保护严厉地在 allogeneic 怀孕期间被节制,尽管有病原体特定的 CD8 + T 房间的数字、功能的保藏。更重要地,因为各在怀孕和天真的怀孕控制以前与稀释 Lm 接种的老鼠在怀孕期间在 Lm 感染以后从单个 concepti 显示出近完全的胎儿的再吞和病原体恢复, preconceptual priming 不在 utero 侵略或胎儿的消耗量免于。显著地,对有在 allogeneic 怀孕的 preconceptual priming 的出生前的 Lm 感染的保护的缺乏在 syngeneic 怀孕期间被恢复。因此,母亲胎儿的抗原不和在出生前的 Lm 感染以后对胎儿的复杂并发症支配 preconceptual 种痘的低效率,尽管有病原体特定的 CD8 + T 房间的数字、功能的保藏。 | Dayna R Clark Vandana Chaturvedi Jeremy M Kinder Tony T Jiang Lijun Xin James M Ertelt Sing Sing Way | 2014 | Cellular & Molecular Immunology2014，11，6： | 3 |
| 4 | Appropriate use of GI endoscopy显示文摘 | Dayna S. Early Tamir Ben-Menachem G. Anton Decker John A. Evans Robert D. Fanelli Deborah A. Fisher Norio Fukami Joo Ha Hwang Rajeev Jain Terry L. Jue Khalid M. Khan Phyllis M. Malpas John T. Maple Ravi S. Sharaf Jason A. Dominitz Brooks D. Cash | 2012 | Gastrointestinal Endoscopy2012，，6： | 2 |
| 5 | Incidence of Sedation-Related Complications With Propofol Use During Advanced Endoscopic Procedures显示文摘 | Gregory A. Coté Robert M. Hovis Michael A. Ansstas Lawrence Waldbaum Riad R. Azar Dayna S. Early Steven A. Edmundowicz Daniel K. Mullady Sreenivasa S. Jonnalagadda | 2010 | Clinical Gastroenterology and Hepatology2010，，2： | 2 |
| 6 | Adverse events of upper GI endoscopy显示文摘 | Tamir Ben-Menachem G. Anton Decker Dayna S. Early Jerry Evans Robert D. Fanelli Deborah A. Fisher Laurel Fisher Norio Fukami Joo Ha Hwang Steven O. Ikenberry Rajeev Jain Terry L. Jue Khalid M. Khan Mary L. Krinsky Phyllis M. Malpas John T. Maple Ravi N. S | 2012 | Gastrointestinal Endoscopy2012，，4： | 2 |
| 7 | Complications of ERCP显示文摘 | Michelle A. Anderson Laurel Fisher Rajeev Jain John A. Evans Vasundhara Appalaneni Tamir Ben-Menachem Brooks D. Cash G. Anton Decker Dayna S. Early Robert D. Fanelli Deborah A. Fisher Norio Fukami Joo Ha Hwang Steven O. Ikenberry Terry L. Jue Khalid M. Kh | 2012 | Gastrointestinal Endoscopy2012，，3： | 2 |
| 8 | Prevalence of missed adenomas in patients with inadequate bowel preparation on screening colonoscopy显示文摘 | Reena V. Chokshi Christine E. Hovis Thomas Hollander Dayna S. Early Jean S. Wang | 2012 | Gastrointestinal Endoscopy2012，，6： | 2 |
| 9 | Preservation and Incorporation of Valuable Endoscopic Innovations (PIVI) on the use of endoscopy simulators for training and assessing skill显示文摘 | Jonathan Cohen Brian P. Bosworth Amitabh Chak Brian J. Dunkin Dayna S. Early Lauren B. Gerson Robert H. Hawes Adam V. Haycock Juergen H. Hochberger Joo Ha Hwang John A. Martin Peter R. McNally Robert E. Sedlack Melina C. Vassiliou | 2012 | Gastrointestinal Endoscopy2012，，3： | 1 |
| 10 | The role of endoscopy in Barrett’s esophagus and other premalignant conditions of the esophagus显示文摘 | John A. Evans Dayna S. Early Norio Fukami Tamir Ben-Menachem Vinay Chandrasekhara Krishnavel V. Chathadi G. Anton Decker Robert D. Fanelli Deborah A. Fisher Kimberly Q. Foley Joo Ha Hwang Rajeev Jain Terry L. Jue Khalid M. Khan Jenifer Lightdale Phyllis M | 2012 | Gastrointestinal Endoscopy2012，，6： | 1 |
| 11 | Teaching computer science with virtual worlds显示文摘 | Brian M Slator Curt Hill Dayna Del Val | 2004 | IEEE Transactions on Education2004，47，2： | 1 |
| 12 | Validation of a Next-Generation Sequencing Assay for Clinical Molecular Oncology显示文摘 | Catherine E. Cottrell Hussam Al-Kateb Andrew J. Bredemeyer Eric J. Duncavage David H. Spencer Haley J. Abel Christina M. Lockwood Ian S. Hagemann Stephanie M. O’Guin Lauren C. Burcea Christopher S. Sawyer Dayna M. Oschwald Jennifer L. Stratman Dorie A. Sh | 2014 | The Journal of Molecular Diagnostics2014，，1： | 1 |
| 13 | Super shedding of Escherichia coli O157:H7 by cattle and the impact on beef carcass contamination 显示文摘 | Terrance M A Dayna M B Joseph M B | 2010 | Meat Science2010，，86： | 1 |
| 14 | Vohwinkel' s syndrome in three generations 显示文摘 | RENEE RS DAYNA GD ZOLTAN T | 2001 | J Am Acad Dermatol2001，44，： | 1 |
| 15 | Clipping prevents perforation in large, flat polyps显示文摘AIM To determine if prophylactic clipping of post-polypectomy endoscopic mucosal resection(EMR) mucosal defects of large,flat,right sided polyps prevents perforations.METHODS IRB approved review of all colonoscopies,and prospective data collection of grasp and snare EMR performed by 2 endoscopists between January 1,2010 and March 31,2014 in a community ambulatory endoscopy center.The study consisted of two phases.In the first phase,all right-sided,flat polyps greater than or equal to 1.2 cm in size were removed using the grasp and snare technique.Clipping was done at the discretion of the endoscopist.In the second phase,all mucosal defects were closed using resolution clips.Phase 2 of the study was powered to detect a statistically significant difference in perforation rate with 148 EMRs,if less than or equal to 2 perforations occurred.RESULTS In phase 1 of the study,2121 colonoscopies were performed.Seventy-five patients had 95 large polyps removed.There were 4 perforations in 95 polypectomies(4.2%).The perforations occurred in polyps ranging in size from 1.5 cm to 2.5 cm.In phase 2,there were 2464 colonoscopies performed.One hundred and sixteen patients had 151 large polyps removed,and all mucosal defects were clipped.There were no perforations(P=0.0016).There were no post-polypectomy hemorrhages in either phase.An average of 2.15 clips were required to close the mucosal defects.The median time to perform the polypectomy and clipping was 13 min,and the median procedure duration was 40 min.Five percent of all patients undergoing colonoscopy in our community based,ambulatory endoscopy center had flat,right sided polyps greater than or equal to 1.2 cm in size.CONCLUSION Prophylactic clipping of the mucosal resection defect of large,right-sided,flat polyps reduces the incidence of perforation. | Daniel Luba Mona Raphael Dayna Zimmerman Joseph Luba Jon Detka James DiSario | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，3： | 1 |
| 16 | A retrograde-viewing device improves detection of adenomas in the colon: a prospective efficacy evaluation (with videos)显示文摘 | Jerome D. Waye Russell I. Heigh David E. Fleischer Jonathan A. Leighton Suryakanth Gurudu Leslie B. Aldrich Jiayi Li Sanjay Ramrakhiani Steven A. Edmundowicz Dayna S. Early Sreenivasa Jonnalagadda Robert S. Bresalier William R. Kessler Douglas K. Rex | 2010 | Gastrointestinal Endoscopy2010，，3： | 1 |
| 17 | Stenting for malignant colonic obstruction: a comparison of efficacy and complications in colonic versus extracolonic malignancy显示文摘 | Rajesh N. Keswani Riad R. Azar Steven A. Edmundowicz Qin Zhang Tarek Ammar Bhaskar Banerjee Dayna S. Early Sreenivasa S. Jonnalagadda | 2009 | Gastrointestinal Endoscopy2009，，3： | 1 |
| 18 | Benefit of intravenous antispasmodic (hyoscyamine sulfate) as premedication for colonoscopy显示文摘 | John B. Marshall Mrunal Patel Ravish J. Mahajan Dayna S. Early Paul D. King Bhaskar Banerjee | 1999 | Gastrointestinal Endoscopy1999，，6： | 1 |
| 19 | Androgen and estrogen ( a ) receptor localization on periaqueductal gray neurons projecting to the rostral ventromedial medulla in the male and female rat 显示文摘 | Dayna R L Anne Z M | 2008 | Journal of Chemical Neuroanatomy2008，36，1： | 1 |
| 20 | Endoscopic Mucosal Resection Results in Change of Histologic Diagnosis in Barrett’s Esophagus Patients with Visible and Flat Neoplasia: A Multicenter Cohort Study显示文摘 | Sachin Wani Julian Abrams Steven A. Edmundowicz Srinivas Gaddam Christine E. Hovis Daniel Green Neil Gupta April Higbee Ajay Bansal Amit Rastogi Dayna Early Charles J. Lightdale Prateek Sharma | 2013 | Digestive Diseases and Sciences2013，，： | 1 |
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