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| 1 | Samarium doped apatite-type orange-red emitting phosphor Ca5(PO4)2SiO4 with satisfactory thermal properties for n-UV w-LEDs显示文摘A novel single-phase Sm^3+activated Ca5(PO4)2SiO4 phosphor was successfully fabricated via a conventional solid-state method,which can be e fficie ntly excited by near ultraviolet(n-UV)light-emitting chips.The crystal structure and luminescence properties were characterized and analyzed systematically by using relevant instruments.The Ca5(PO4)2SiO4:Sm^3+phosphor shows an orange-red emission peaking at600 nm under the excitation of 403 nm and the optimal doping concentration of Sm^3+is determined to be 0.08,The critical distance of Ca5(PO4)2SiO4:0.08 Sm^3+is calculated to be 1.849 nm and concentration quenching mechanism of the Sm^3+in Ca5(PO4)2SiO4 host is ascribed to energy transfer between nearestneighbor activators.The decay time of Ca5(PO4)2 SiO4:0,08 Sm^3+is determined to be 1.1957 ms.In addition,the effect of temperature on the emission intensity was also studied,72.4%of the initial intensity is still preserved at 250℃,better thermal stability compared to commercial phosphor YAG:Ce^3+indicates that Ca5(PO4)2SiO4:0.08 Sm^3+has excellent thermal stability and active energy is deduced to be 0.130 eV.All the results demonstrate that orange-red emitting Ca5(PO4)2SiO4:0.08 Sm3+phosphor exhibits good luminescent properties.Owing to the excellent thermal quenching luminescence property,Ca5(PO4)2SiO4:0.08 Sm^3+phosphor can be applied in n-UV white light emitting diodes and serve as the warm part of white light. | Ze Zhang Jialiang Niu Wei Zhou Dingdian Xu Huanhuan Du | 2019 | Journal of Rare Earths2019，37，9： | 5 |
| 2 | Fabrication of niobium doped titanate nanoflakes with enhanced visible-light-driven photocatalytic activity for efficient ibuprofen degradation显示文摘In this study,a novel class of niobium(Nb) doped titanate nanoflakes(TNFs) are fabricated through a onestep hydrothermal method.Nb doping affects the curving of titanate nanosheet,leading to the formation of nanoflake structure.In addition,Nb5+ filled in the interlayers of [TiO6] alters the light adsorption property of pristine titanate.The band gap of Nb-TNFs is narrowed to 2.85 eV,while neat titanate nano tubes(TNTs) is 3.4 eV.The enhanced visible light adsorption significantly enhances the visible-lightdriven activity of Nb-TNFs for ibuprofen(IBP) degradation.The pseudo-first order kinetics constant for Nb-TNFs is calculated to be 1.04 h^-1,while no obvious removal is observed for TNTs.Photo-generated holes(h^+) and hydroxyl radicals(·OH) are responsible for IBP degradation.The photocatalytic activity of Nb-TNFs depends on pH condition,and the optimal pH value is found to be 5.In addition,Nb-TNFs exhibited superior photo-stability during the reuse cycles.The results demonstrated Nb-TNFs are very promising in photocatalytic water purification. | Wen Liu Wei Zhang Mushi Liu Penghui Du Chenyuan Dang Jialiang Liang Yunyi Li | 2019 | Chinese Chemical Letters2019，30，12： | 3 |
| 3 | Efficacy,safety and immunogenicity of hexavalent rotavirus vaccine in Chinese infants显示文摘A randomized,double-blind,placebo-controlled multicenter trial was conducted in healthy Chinese infants to assess the efficacy and safety of a hexavalent live human-bovine reassortant rotavirus vaccine(HRV)against rotavirus gastroenteritis(RVGE).A total of 6400 participants aged 6-12 weeks were enrolled and randomly assigned to either HRV(n?3200)or placebo(n?3200)group.All the subjects received three oral doses of vaccine four weeks apart.The vaccine efficacy(VE)against RVGE caused by rotavirus serotypes contained in HRV was evaluated from 14 days after three doses of administration up until the end of the second rotavirus season.VE against severe RVGE,VE against RVGE hospitalization caused by serotypes contained in HRV,and VE against RVGE,severe RVGE,and RVGE hospitalization caused by natural infection of any serotype of rotavirus were also investigated.All adverse events(AEs)were collected for 30 days after each dose.Serious AEs(SAEs)and intussusception cases were collected during the entire study.Our data showed that VE against RVGE caused by serotypes contained in HRV was 69.21%(95%CI:53.31-79.69).VE against severe RVGE and RVGE hospitalization caused by serotypes contained in HRV were 91.36%(95%CI:78.45-96.53)and 89.21%(95%CI:64.51-96.72)respectively.VE against RVGE,severe RVGE,and RVGE hospitalization caused by natural infection of any serotype of rotavirus were 62.88%(95%CI:49.11-72.92),85.51%(95%CI:72.74-92.30)and 83.68%(95%CI:61.34-93.11).Incidences of AEs from the first dose to one month post the third dose in HRV and placebo groups were comparable.There was no significant difference in incidences of SAEs in HRV and placebo groups.This study shows that this hexavalent reassortant rotavirus vaccine is an effective,well-tolerated,and safe vaccine for Chinese infants. | Zhiwei Wu Qingliang Li Yan Liu Huakun Lv Zhaojun Mo Fangjun Li Qingchuan Yu Fei Jin Wei Chen Yong Zhang Teng Huang Xiaosong Hu Wei Xia Jiamei Gao Haisong Zhou Xuan Bai Yueyue Liu Zhenzhen Liang Zhijun Jiang Yingping Chen Jiuwei Zhang Jialiang Du Biao Yang Bo Xing Yantao Xing Ben Dong Qinghai Yang Chen Shi Tingdong Yan Bo Ruan Haiyun Shi Xingliang Fan Dongyang Feng Weigang Lv Dong Zhang Xiangchu Kong Liuyifan Zhou Dinghong Que Hong Chen Zhongbing Chen Xiang Guo Weiwei Zhou Cong Wu Qingrong Zhou Yuqing Liu Jian Qiao Ying Wang Xinguo Li Kai Duan Yuliang Zhao Gelin Xu Xiaoming Yang | 2022 | Virologica Sinica2022，37，5： | 2 |
| 4 | Genotypes Diversity of Acute Gastroenteritis Outbreaks Caused by Human Sapovirus-Beijing Municipality,China,2015-2021显示文摘Introduction:Human sapovirus(HuSaV)is an enteric virus responsible for sporadic cases and outbreaks of acute gastroenteritis(AGE)globally.A seven-year active surveillance study was conducted to investigate the molecular epidemiology of HuSaVs associated with AGE outbreaks in Chaoyang District of Beijing Municipality,China from January 2015 to December 2021.Methods:Fecal and anal swab samples were obtained from patients experiencing AGE outbreaks.HuSaVs were identified through reverse transcription polymerase chain reaction(RT-PCR),and partial viral protein 1(VP1)sequences(approximately 434 base pairs)were utilized for genotyping,single nucleotide polymorphism(SNP)analysis,and phylogenetic examination.Results:HuSaVs were identified in 71 AGE outbreaks,demonstrating a detection rate of 10.5%,second only to norovirus.The primary demographic affected by HuSaV were children under the age of 5 in kindergarten settings.Infection rates tended to peak during two distinct periods:May to June and September to December.Upon genotyping,seven distinct genotypes emerged.GII.3 was the most prevalent,accounting for 54.9%of cases,followed by GI.1(12.7%),GI.2(9.9%),GII.5(7.0%),GI.5(2.8%),GI.6(1.4%),GII.1(1.4%),and untyped cases(9.9%).A phylogenetic analysis of GII.3 identified three distinct groups,with 15 notable SNPs observed.Conclusions:This study offers a comprehensive analysis of the persistent prevalence of HuSaV outbreaks in Chaoyang District,Beijing Municipality,China.Over time,the diversity of HuSaV subtypes has shifted,and it is now recognized as the second leading viral agent responsible for AGE outbreaks.This highlights the importance of ongoing surveillance in the future. | Yang Jiao Taoli Han Xiao Qi Yan Gao Jianhong Zhao Yue Zhang Beibei Li Zheng Zhang Jialiang Du Lingli Sun | 2023 | China CDC weekly2023，5，28： | 1 |
| 5 | Characterization of human rabies virus vaccine strain in China 显示文摘 | Du Jialiang Zhang Qiang Tang Qing | 2008 | Virus Res2008，135，2： | 1 |
| 6 | Genetic variation and an estimation of effective population size in the pearl oyster Pinctada martensii显示文摘 | Liu Qingyun Chen Weiyao Liu Jialiang Ronglian Huang Qingheng Wang Yu Jiao Du Xiaodong Deng Yuewen Li Junhui | 2014 | Biochemical Systematics and Ecology2014，，： | 1 |
| 7 | Molecular characterization of the complete genome of a street rabies virus isolated in China显示文摘 | Ming Pinggang Du Jialiang Tang Qing | 2009 | Virus Res2009，143，： | 1 |
| 8 | Observation of magnetic droplets in magnetic tunnel junctions显示文摘Magnetic droplets,a class of highly nonlinear magnetodynamic solitons,can be nucleated and stabilized in nanocontact spintorque nano-oscillators.Here we experimentally demonstrate magnetic droplets in magnetic tunnel junctions(MTJs).The droplet nucleation is accompanied by power enhancement compared with its ferromagnetic resonance modes.The nucleation and stabilization of droplets are ascribed to the double-Co Fe B free-layer structure in the all-perpendicular MTJ,which provides a low Zhang-Li torque and a high pinning field.Our results enable better electrical sensitivity in fundamental studies of droplets and show that the droplets can be utilized in MTJ-based applications and materials science. | Kewen Shi Wenlong Cai Sheng Jiang Daoqian Zhu Kaihua Cao Zongxia Guo Jiaqi Wei Ao Du Zhi Li Yan Huang Jialiang Yin Johan Akerman Weisheng Zhao | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，2： | 0 |
| 9 | TMEM106A transcriptionally regulated by promoter methylation is involved in invasion and metastasis of hepatocellular carcinoma显示文摘Expression of transmembrane protein 106A(TMEM106A)has been reported to be dysregulated in several types of cancers.However,the role of TMEM106A in hepatocellular carcinoma(HCC)is still unknown.In the present study,we demonstrate that TMEM106A is markedly downregulated in HCC compared with normal liver tissue.In particular,tumor-specific DNA methylation of TMEM106A is frequently observed in tumor tissues from HCC patients.Immunohistochemistry and pyrosequencing reveal a significant relationship between TMEM106A methylation and downregulation of protein expression.Receiver operating characteristic(ROC)curve analysis reveals that methylation of TMEM106A in tumor samples is different from that in non-malignant adjacent tissues of HCC patients.Moreover,HCC patients with TMEM106A hypermethylation have a poor clinical prognosis.5-Aza-2′-deoxycytidin treatment of hypermethylated TMEM106A in highly metastatic HCC cells increases the expression of TMEM106A.Functional assays reveal that overexpression of TMEM106A significantly suppresses the malignant behavior of HCC cells in vitro and decreases tumorigenicity and lung metastasis in vivo.Mechanistically,TMEM106A inhibits epithelial mesenchymal transition(EMT)of HCC cells through inactivation of the Erk1/2/Slug signaling pathway.In conclusion,our findings demonstrate that TMEM106A is an inhibitor of HCC EMT and metastasis,and TMEM106A is often transcriptionally downregulated by promoter methylation,which results in reduced levels of TMEM106A protein and predicts poor survival outcomes for HCC patients. | Shiming Shi Biao Wang Jinglei Wan Lina Song Guiqi Zhu Junxian Du Luxi Ye Qianqian Zhao Jialiang Cai Qing Chen Kun Xiao Jian He Lei Yu Zhi Dai | 2022 | Acta Biochimica et Biophysica Sinica2022，54，7： | 0 |
| 10 | Implementation of 16 Boolean logic operations based on one basic cell of spin-transfer-torque magnetic random access memory显示文摘In-memory computing(IMC)systems based on emerging nonvolatile memories(NVMs)provide a thorough solution for memory wall issues and von Neumann bottlenecks.Massive IMC schemes have been proposed by utilizing ingenious structures and additional auxiliary components.However,these schemes are not compatible with the basic cell(one memory unit and one transistor)of emerging random-access memory(RAM),which goes against low-power and high-density requirements.In this paper,we propose a logic implementation scheme based on one magnetic tunnel junction and one transistor(1MTJ-1T),which is the basic cell of spin-transfer-torque magnetic RAM(STT-MRAM).With no other assistance,complete 16 logic operations can be accomplished in two steps with their logic outputs in-situ stored in the MTJ.The area(0.2μm^(2))and energy consumption per logic operation(1.1-2.6 pJ)of the logic gates under 14 nm process node are evaluated using SPICE simulations,indicating its excellent performance.Our work exhibits a 1MTJ-1Tbased logic operation implementation,which can bridge the gap between STT-MRAM and high-performance IMC applications. | Yan HUANG Kaihua CAO Kun ZHANG Jinkai WANG Kewen SHI Zuolei HAO Wenlong CAI Ao DU Jialiang YIN Qing YANG Junfeng LI Jianfeng GAO Chao ZHAO Weisheng ZHAO | 2023 | Science China(Information Sciences)2023，66，6： | 0 |
| 11 | Mechanism of field-like torque in spin-orbit torque switching of perpendicular magnetic tunnel junction显示文摘The current-induced spin-orbit torque(SOT) is one of the most promising ways for high speed and low power spintronics devices. However, the mechanism of SOT driven magnetization reversal, especially the role of the field-like torque(FLT), is still unclear. Here, we report the observed promotion and suppression of switching by FLT, which depends on the relative direction of FLT and spin polarization. Our results reveal that the FLT could modulate the switching speed and power consumption by affecting the work done by the damping-like torque, and leads two different reversal dynamical paths during the switching.Furthermore, the origin of incubation time in SOT induced switching is clarified simultaneously. | Yudong Zhuo Wenlong Cai Daoqian Zhu Hongchao Zhang Ao Du Kaihua Cao Jialiang Yin Yan Huang Kewen Shi Weisheng Zhao | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，10： | 0 |
| 12 | 建立具有体内胚内和胚外发育潜能的多能干细胞显示文摘文章简介在已知的体外培养的干细胞类型当中,多能干细胞具有最高的发育潜能,能够形成构成成年个体的所有细胞类型。但是,多能干细胞很难在体内发育过程中形成胚外的胎盘组织。 | Yang Yang Bei Liu Jun Xu Jinlin Wang Jun Wu Cheng Shi Yaxing Xu Jiebin Dong Chengyan Wang Weifeng Lai Jialiang Zhu Liang Xiong Dicong Zhu Xiang Li Weifeng Yang Takayoshi Yamauchi Atsushi Sugawara Zhongwei Li Fangyuan Sun Xiangyun Li Chen Li Aibin He Yaqin Du Ting Wang Chaoran Zhao Haibo Li Xiaochun Chi Hongquan Zhang Yifang Liu Cheng Li Shuguang Duo Ming Yin 沈浣 Juan Carlos Izpisua Belmonte 邓宏魁 | 2018 | 科学新闻2018，0，4： | 0 |
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