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| 1 | A rare case of hypokalemia-induced rhabdomyolysis显示文摘 | Rong HE Wen-Jia GUO Fei SHE Guo-Bin MIAO Fang LIU Ya-Jun XUE Yuan-Wei LIU Hao-Tian WANG Ping ZHANG | 2018 | Journal of Geriatric Cardiology2018，15，4： | 6 |
| 2 | The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients显示文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus. | Jin Liu Lingling Bian Li Ji Yang Chen Heng Chen Yong Gu Bingqin Ma Wei Gu Xinyu Xu Yun Shi Jian Wang Dalong Zhu Zilin Sun Jianhua Ma Hui Jin Xing Shi Heng Miao Bing Xin Yan Zhu Zhenwen Zhang Ruifang Bu Lan Xu Guangde Shi Wei Tang Wei Li Dongmei Zhou Jun Liang Xingbo Cheng Bimin Shi Jixiang Dong Ji Hu Chen Fang Shao Zhong Weinan Yu Weiping Lu Chenguang Wu Li Qian Jiancheng Yu Jialin Gao Xiaoqiang Fei Qingqing Zhang Xueqin Wang Shiwei Cui Jinluo Cheng Ning Xu Guofeng Wang Guoqing Han Chunrong Xu Yun Xie Minmin An Wei Zhang Zhixiao Wang Yun Cai Qi Fu Yu Fu Shuai Zheng Fan Yang Qingfang Hu Hao Dai Yu Jin Zheng Zhang Kuanfeng Xu Yifan Li Jie Shen Hongwen Zhou Wei He Xuqin Zheng Xiao Han Liping Yu Jinxiong She Mei Zhang Tao Yang | 2016 | Science China(Life Sciences)2016，59，9： | 5 |
| 3 | Expression of reconstructive hF Ⅷ in the hrDNA by using hrDNA targeting vector显示文摘Our lab has constructed a new nonviral vec-tor—hrDNA targeting vector(pHrneo). pHrneo is a human derived vector that can target gene into human ribosomal DNA(hrDNA) locus. In this study, we inserted expression cassette of reconstructive hF Ⅷ (hFVIII-BDDAK39) to pHrneo to construct targeting vector: pHrneo-BDDAK39. Through electroporation of pHrneo-BDDAK39 into HT1080 cells, we identified the homologous recombinants by PCR and Southen blotting, and tested the expression of hFVIII- BDDAK39 in the hrDNA locus. The hFⅧ-BDDAK39 was successfully targeted into hrDNA locus of HT-1080 by pHrneo-BDDAK39, and the efficiency of site-specific inte-gration was 2.0×10?5. hFⅧ-BDDAK39 in hrDNA locus of HT-1080 is found to be able to express efficiently (32±5 ng·106 cells?1·24 h?1). Targeting vector pHrneo-BDDAK39 can find use in gene therapy for hemophilia. | LIU Xionghao LIU Mujun SHE Hua WEN Lu XUE Zhigang LIANG Desheng CAI Fang PAN Qian LONG Zhigao WU Lingqian DAI Heping XIA Kun XlA Jiahui | 2005 | Chinese Science Bulletin2005，50，19： | 5 |
| 4 | First experimental constraints on WIMP couplings in the effective field theory framework from CDEX显示文摘We present weakly interacting massive particles(WIMPs) search results performed using two approaches of effective field theory from the China Dark Matter Experiment(CDEX), based on the data from both CDEX-1B and CDEX-10 stages. In the nonrelativistic effective field theory approach, both time-integrated and annual modulation analyses were used to set new limits for the coupling of WIMP-nucleon effective operators at 90% confidence level(C.L.) and improve over the current bounds in the low mχregion. In the chiral effective field theory approach, data from CDEX-10 were used to set an upper limit on WIMP-pion coupling at 90% C.L. We for the first time extended the limit to the m_(χ)<6 GeV/c^(2) region. | Yi Wang Zhi Zeng Qian Yue LiTao Yang KeJun Kang YuanJing Li Mehment Agartioglu HaiPeng An JianPing Chang JingHan Chen YunHua Chen JianPing Cheng Cheng Yi Chiang WenHan Dai Zhi Deng ChangHao Fang XinPing Geng Hui Gong QiuJu Guo XuYuan Guo HongJian He Li He ShengMing He JinWei Hu TuChen Huang HanXiong Huang HaiTao Jia LiPing Jia Xi Jiang HauBin Li JianMin Li Jin Li MingXuan Li RenMingJie Li Xia Li YuLan Li Bin Liao FongKay Lin ShinTed Lin ShuKui Liu YanDong Liu Yu Liu YuanYuan Liu ZhongZhi Liu Hao Ma YuCai Mao QiYuan Nie JinHua Ning Hui Pan NingChun Qi Jie Ren XiChao Ruan ChangSong Shang Vivek Sharma Ze She Lakhwinder Singh Monoj Kumar Singh TianXi Sun ChangJian Tang WeiYou Tang Yang Tian GuangFu Wang Li Wang Qing Wang Yu Chen Wang YunXiang Wang Zhen Wang Henry Tsz-King Wong ShiYong Wu YuCheng Wu HaoYang Xing Yin Xu Tao Xue YuLu Yan Nan Yi ChunXu Yu HaiJun Yu JianFeng Yue Ming Zeng BingTao Zhang Lei Zhang FengShou Zhang ZhenYu Zhang KangKang Zhao MingGang Zhao JiFang Zhou ZuYing Zhou JingJun Zhu | 2021 | Science China(Physics,Mechanics & Astronomy)2021，64，8： | 3 |
| 5 | Fast consensus seeking for multi-agent systems显示文摘For multi-agent systems based on the local information,the agents automatically converge to a common consensus state and the convergence speed is determined by the algebraic connectivity of the communication network.To study fast consensus seeking problems of multi-agent systems in undirected networks,a consensus protocol is proposed which considers the average information of the agents' states in a certain time interval,and a consensus convergence criterion for the system is obtained.Based on the frequency-domain analysis and algebra graph theory,it is shown that if the time interval is chosen properly,then requiring the same maximum control effort the proposed protocol reaches consensus faster than the standard consensus protocol.Simulations are provided to demonstrate the effectiveness of these theoretical results. | Yingying She Huajing Fang | 2011 | Journal of Systems Engineering and Electronics2011，22，3： | 3 |
| 6 | Seasonal variation of microelement contents in leaves of Cyclocarea paliurus among the provenances显示文摘Cyclocarya paliurus as a multiple function plant can accumulate biologically important microelement elements.To reveal the variation of selected microelement concentrations in leaves of C.paliurus provenances during the growing season,12 C.paliurus provenances in the field trial were sampled five times at approximately 1-month intervals.The method of inductively coupled plasma optical emission spectrometer(ICP-OES) was employed to determinate average concentrations of Fe,Mn,Zn,Cu and Se in leaves of 12 C.paliurus provenances.The results show that on average,the concentrations of five microelement in the leaves follows an order of Fe > Mn > Zn > Cu > Se.Variance analysis shows that there are significant differences in Fe,Mn and Zn concentrations among the twelve provenances(p<0.05),while there is no significant difference between Cu and Se concentrations.A significant difference was also observed in the concentrations of five microelements at the different sampling times(p<0.001),but the mean concentrations for each microelement showed different temporal dynamic patterns.Meanwhile,a significant correlation between concentrations of Se and other measured microelements was detected in the leaves of C.paliurus,except for Mn.Obtained results not only demonstrated that leaves of C.paliurus exhibited higher levels of microelements(Fe,Mn,Cu,Zn and Se),but also provided a basis for breeding strategies of superior provenances with rich content of microelements,and choosing optimum harvesting time for food industry in future. | FANG Sheng-zuo CHU Xiu-li SHANG Xu-lan YANG Wan-xia FU Xiang-xiang SHE Cheng-qi | 2011 | Journal of Forestry Research2011，22，2： | 3 |
| 7 | Protective effect of Sijunzi decoction on neuromuscular junction ultrastructure in autoimmune myasthenia gravis rats显示文摘OBJECTⅣE: To investigate the protective role of Sijunzi decoction in neuromuscular junction(NMJ)and muscle cell mitochondria ultrastructure; as well as its effects on the amount of adenosine triphosphate(ATP) and the activities of mitochondrial respiratory chain complexes I, Ⅱ, Ⅲ, and Ⅳ in autoimmune myasthenia gravis rats.METHODS: An experimental autoimmune myasthenia gravis(EAMG) rat model was established by inoculating rats with acetylcholine receptors extracted from Torpedo. Rats were divided into three groups: model, prednisone, and Sijunzi decoction, and were fed physiological saline, prednisone, or Sijunzi decoction, respectively. NMJ and muscle cell mitochondria ultrastructure were observed by transmission electron microscope. The amount of ATP was assessed by high performance liquid chromatography. The activities ofmitochondrial respiratory chain complexes I, Ⅱ, Ⅲ,and Ⅳ was determined using the Clark oxygen electrode method.RESULTS: In the model group, there were sparse muscle fibers, with decreased mitochondria, and sparse, diffluent, or absent NMJ folds. After intervention with Sijunzi decoction, the above pathology changes were improved: muscle fiber structure was clear and complete; the mitochondria count was higher; and the NMJ structure was close to normal. Gastrocnemius muscle mitochondria in the model group produced significantly less ATP than those in the prednisone group(P<0.01). Conversely, the ATP of Sijunzi decoction group was significantly higher than prednisone group(P<0.01). The activities of gastrocnemius muscle mitochondrial respiratory chain complexes I, Ⅱ, Ⅲ, and Ⅳ in both the prednisone and Sijunzi decoction groups was dramatically higher compared with the model group(P<0.05). The activities of complexes I and Ⅲ in the Sijunzi decoction group were significantly higher than those in the prednisone group(P<0.05), but there was no obvious difference in complex Ⅱ or Ⅳ activities between the two groups(P>0.05).CONCLUSION: Sijunzi decoction improved pathological changes in muscle mitochondria and NMJ,enhanced the amount of ATP in gastrocnemius muscle mitochondria, and improved the activities of respiratory chain complexes I, Ⅱ, Ⅲ, and Ⅳ(especially I and Ⅲ) of the EAMG rats. | HaibinWu Shifeng She Youzhang Liu Wensheng Xiong Yalei Guo Huansong Fang Hong Chen Jia Li | 2013 | Journal of Traditional Chinese Medicine2013，33，5： | 3 |
| 8 | Tailoring of electromagnetic field localizations by twodimensional graphene nanostructures显示文摘Graphene has great potential for enhancing light−matter interactions in a two-dimensional regime due to surface plasmons with low loss and strong light confinement.Further utilization of graphene in nanophotonics relies on the precise control of light localization properties.Here,we demonstrate the tailoring of electromagnetic field localizations in the mid-infrared region by precisely shaping the graphene into nanostructures with different geometries.We generalize the phenomenological cavity model and employ nanoimaging techniques to quantitatively calculate and experimentally visualize the two-dimensional electromagnetic field distributions within the nanostructures,which indicate that the electromagnetic field can be shaped into specific patterns depending on the shapes and sizes of the nanostructures.Furthermore,we show that the light localization performance can be further improved by reducing the sizes of the nanostructures,where a lateral confinement of λ0/180 of the incidence light can be achieved.The electromagnetic field localizations within a nanostructure with a specific geometry can also be modulated by chemical doping.Our strategies can,in principle,be generalized to other two-dimensional materials,therefore providing new degrees of freedom for designing nanophotonic components capable of tailoring two-dimensional light confinement over a broad wavelength range. | Ze-Bo Zheng Jun-Tao Li Teng Ma Han-Lin Fang Wen-Cai Ren Jun Chen Jun-Cong She Yu Zhang Fei Liu Huan-Jun Chen Shao-Zhi Deng Ning-Sheng Xu | 2017 | Light(Science & Applications)2017，6，1： | 2 |
| 9 | Security Situation in Afghanistan显示文摘In the first half of 2006, the Taliban armed forces intensified their terrorist attacks in Afghanistan, thus drawing attention of the international community. The worse situation there will inevitably produce negative impacts on the security in the west regions of China. Based on a thorough analysis of the situation, the author concluded that the low-intensity conflicts there would continue in some time to come. | Dr. Fang Jinying is an Associate Professor of the Institutes of Security and Strategic Studies, China Institutes of Contemporary International Relations (CICIR). Her major academic interests are in the worldwide Islamic extremism and South Asian security. She has written a number of articles. She is also the author of The Emergency and Development of “Ethnic Chinese Issue” in Southeast Asia (2001), and coauthor of Focus on Global Ethnic Issues (2001) and Focus on World Religious Issues (2003). | 2006 | Contemporary International Relations2006，16，6： | 2 |
| 10 | Simultaneous detection and characterization of toxigenic Clostridium difficile directly from clinical stool specimens显示文摘我们采用了结合的复合聚合酶链反应(PCR ) 指向六的毛状的电气泳动(mPCR-CE ) 在为 toxigenic C 的同时的察觉和描述的 tcdC 的 Clostridium 顽固基因,包括的 tpi, tcdA, tcdB, cdtA, cdtB,和删除。顽固直接从烘便的标本。mPCR-CE 每反应有 10 个形成殖民地的单位的察觉的限制没有与另外的相关细菌的基因跨反应。临床的确认在 354 上被执行连续地与怀疑的 C 从病人收集了凳子标本。顽固感染并且 45 孤立。结果与与 BD 最大 Cdiff,即时房间分析试金(RTCA ) ,和 mPCR-CE 相结合的一个参考标准相比。toxigenic C。顽固种类在 36 被检测孤立并且由 mPCR-CE 的 45 个凳子标本,它提供了 20.3% 的积极的率(81/399 ) 。mPCR-CE 有 97.2% 的特性和 96.0% 的敏感,它比 RTCA 高(x 2= 5.67, P = 0.017 ) 但是比 BD 最大 Cdiff 低(P = 0.245 ) 。在 45 紧张之中,(97.8%) 44 作为 non-ribotype 被决定 027 由 mPCR-CE,它充分被适合于 PCR ribotyping。尽管 ribotypes 017 (n = 8, 17.8%) , 001 (n = 6, 13.3%) ,并且 012 (n = 7, 15.6%) 在这个区域是占优势的, ribotype 027 重要遗传型习惯性地被监视。mPCR-CE 为 toxigenic C 的同时的察觉提供了一个其他的诊断工具。在凳子顽固、在 RT027 和 non-RT027 之间潜在地区分。 | Hanjiang Lai Chen Huang Jian Cai Julian Ye Jun She Yi Zheng Liqian Wang Yelin Wei Weijia Fang Xianjun Wang Yi-Wei Tang Yun Luo Dazhi Jin | 2018 | Frontiers of Medicine2018，12，2： | 2 |
| 11 | Investigation of sodium vanadate as a high-performance aqueous zinc-ion battery cathode显示文摘Due to the intrinsic advantages of nontoxicity, low-cost, and abundant resource of metallic zinc, aqueous zinc-ion batteries (ZIBs) have attracted universal interest [1,2]. Tremendous cathode materials have been exploited in aqueous ZIBs, such as manganese-based materials [3-11], Co-based materials [12,13] and vanadium-based materials [14-21]. | Binghong She Lutong Shan Huijie Chen Jiang Zhou Xun Guo Guozhao Fang Xinxin Cao Shuquan Liang | 2019 | Journal of Energy Chemistry2019，28，10： | 2 |
| 12 | Interaction of hsa-miR-381 and glioma suppressor LRRC4 is involved in glioma growth显示文摘 | Hailin Tang Xiaoping Liu Zeyou Wang Xiaoling She Xi Zeng Min Deng Qianjin Liao Xiaofang Guo Rong Wang Xiaoling Li Fang Zeng Minghua Wu Guiyuan Li | 2011 | Brain Research2011，，： | 1 |
| 13 | Improving disturbancerejection performance based on an equivalent-input-disturbance approach显示文摘 | SHE J H FANG M X OHYAMA Y | 2008 | IEEE Transactions on Industrial Electronics2008，55，1： | 1 |
| 14 | Improving disturbance-rejection performance based on an equivalent-input-disturbance approach显示文摘 | She J H Fang M Ohyama Y | 2008 | IEEE Transactions on Industrial Electronics2008，55，1： | 1 |
| 15 | Improving disturbance rejection performance based on an equivalent-input-disturbance approaeh显示文摘 | SHE J H FANG M X OHYAMA Y HASHIMOTO H WU M | 2008 | IEEE Transactions on Industrial Electronics2008，55，1： | 1 |
| 16 | Three New Chromone Derivatives Produced by Phomopsis sp. HNY29-2B from Acanthus ilicifolius Linn.显示文摘三新 chromone 衍生物, phomochromenones 交流(1-3 ) ,和一已知的 chaetocyclinone B (4 ) 从 Phomopsis sp 的文化被获得。HNY29-2B 从红树属植物叶板 ilicifolius 悬崖孤立,它从华南海是镇定的。他们的结构被 1 D NMR 和 2 象集体分光镜的数据一样的 D NMR。1 和 2 的绝对配置被电子圆形的二色性(ECD ) 的量化学药品计算分配系列。化合物 3 是拥有唯一的 chromeno 的碱的第三个例子[3,2-c ] pyridine 原子核。在 bioactivity 试金,化合物 4 与 8.13 和 3.59 污穹摥 ? 穩牯歯? 效正愠摮匠穵歵? 楍慹牵 ? 牣獯 ? 潣的 IC 50 价值对人的前列腺癌症房间线(PC-3 和 DU145 房间) 显示出 cytotoxicity 吗? | Bo Ding Zhiyuan Wang Guoping Xia Xishan Huang Fang Xu Wenrui Chen Zhigang She | 2017 | Chinese Journal of Chemistry2017，35，12： | 1 |
| 17 | Association Between Lipid Profiles and Left Ventricular Hypertrophy:New Evidence from a Retrospective Study显示文摘Objective To explore the association between lipid profiles and left ventricular hypertrophy in a Chinese general population.Methods We conducted a retrospective observational study to investigate the relationship between lipid markers[including triglycerides,total cholesterol,low-density lipoprotein cholesterol,high-density lipoprotein(HDL)cholesterol,non-HDL-cholesterol,apolipoprotein A-I,apolipoprotein B,lipoprotein[a],and composite lipid profiles]and left ventricular hypertrophy.A total of 309,400 participants of two populations(one from Beijing and another from nationwide)who underwent physical examinations at different health management centers between 2009 and 2018 in China were included in the cross-sectional study.7,475 participants who had multiple physical examinations and initially did not have left ventricular hypertrophy constituted a longitudinal cohort to analyze the association between lipid markers and the new-onset of left ventricular hypertrophy.Left ventricular hypertrophy was measured by echocardiography and defined as an end-diastolic thickness of the mterventricular septum or left ventricle posterior wall>11 mm.The Logistic regression model was used in the cross-sectional study.Cox model and Cox model with restricted cubic splines were used in the longitudinal cohort.Results In the cross-sectional study for participants in the highest tertile of each lipid marker compared to the respective lowest,triglycerides[odds ratio(OR):1.2S0,95%CI:1.060 to 1.474],HDL-cholesterol(OR:0.780,95%CI:0.662 to 0.918),and lipoprotein(a)(OR:1.311,95%C7:1.115 to 1.541)had an association with left ventricular hypertrophy.In the longitudinal cohort,for participants in the highest tertile of each lipid marker at the baseline compared to the respective lowest,triglycerides[hazard ratio(HR):3.277,95%C/:1.720 to 6.244],HDL-cholesterol(HR:0.516,95%C7:0.283 to 0.940),non-HDL-cholesterol(HR:2.309,95%C/:1.296 to 4.112),apolipoprotein B(HR:2.244,95%CI:1.251 to 4.032)showed an association with new-onset left ventricular hypertrophy.In the Cox model with forward stepwise selection,triglycerides were the only lipid markers entered into the final model.Conclusion Lipids levels,especially triglycerides,are associated with left ventricular hypertrophy.Controlling triglycerides level potentiate to be a strategy in harnessing cardiac remodeling but deserve to be furdier investigated. | Xuewei Huang Keqiong Deng Juanjuan Qin Fang Lei Xingyuan Zhang Wenxin Wang Lijin Lin Yuming Zheng Dongai Yao Huiming Lu Feng Liu Lidong Chen Guilan Zhang Yueping Liu Qiongyu Yang Jingjing Cai Zhigang She Hongliang Li | 2022 | Chinese Medical Sciences Journal2022，37，2： | 1 |
| 18 | Initial Electrode Kinetics of Anion Intercalation and De-intercalation in Nonaqueous Al-Graphite Batteries显示文摘Graphitic materials with intercalated sites are considered as the mostly used positive electrode materials in nonaqueous Al batteries.Unlike the small-size cations,the intercalation/de-intercalation of large-size anions into/out of graphite would induce large volume expansion and micro-structure reconfiguration,leading to unexpected coulombic efficiency in the full cells(<95%within initial several cycles). | Dan Han Mao-Sheng Cao Na Li Dong-Mei She Wei-Li Song Haosen Chen Shuqiang Jiao Daining Fang | 2021 | Chinese Journal of Chemistry2021，39，1： | 1 |
| 19 | Design of Landscape Ecological Restoration for “Five Mining Areas” of the Laoqing Mountain in the Dianchi Lake Basin显示文摘Through analyzing basic conditions of the 'five mining areas' in the Laoqing Mountain of the Dianchi Lake Basin, in Kunming City, South China, the ecological restoration design of 'integrating engineering protection and biological restoration, building the landscape ecological security pattern of the Laoqing Mountain' was proposed. Considering the different ecological functional areas, varying engineering measures, greening patterns, and irrigation means were selected for the ecological restoration, including site management, vegetation restoration, management and utilization etc.. These ecological restoration measures will produce favorable ecological benefits, and also take landscape effect and sustainable development into consideration, which will contribute to the ecological restoration of the 'five mining areas', and provide a scientific and feasible reference for the ecological restoration in China. | ZHU Guofei HU Yeqing LONG Haijun CAI Fang SHE Lihua | 2019 | Journal of Landscape Research2019，11，2： | 1 |
| 20 | Improving disturb- ance-rejection performance based on an equivalent input-disturb- ance approach 显示文摘 | SHE J H FANG M X OHYAMA Y | 2008 | IEEE Transactions on Industrial Electronics2008，55，1： | 1 |
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