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| 1 | 863 genomes reveal the origin and domestication of chicken显示文摘Despite the substantial role that chickens have played in human societies across the world,both the geographic and temporal origins of their domestication remain controversial.To address this issue,we analyzed 863 genomes from a worldwide sampling of chickens and representatives of all four species of wild jungle fowl and each of the five subspecies of red jungle fowl(RJF).Our study suggests that domestic chickens were initially derived from the RJF subspecies Gallus gallus spadiceus whose present-day distribution is predominantly in southwestern China,northern Thailand and Myanmar.Following their domestication,chickens were translocated across Southeast and South Asia where they interbred locally with both RJF subspecies and other jungle fowl species.In addition,our results show that the White Leghorn chicken breed possesses a mosaic of divergent ancestries inherited from other subspecies of RJF.Despite the strong episodic gene flow from geographically divergent lineages of jungle fowls,our analyses show that domestic chickens undergo genetic adaptations that underlie their unique behavioral,morphological and reproductive traits.Our study provides novel insights into the evolutionary history of domestic chickens and a valuable resource to facilitate ongoing genetic and functional investigations of the world's most numerous domestic animal. | Ming-Shan Wang Mukesh Thakur Min-Sheng Peng Yu Jiang Laurent Alain Francois Frantz Ming Li Jin-Jin Zhang Sheng Wang Joris Peters Newton Otieno Otecko Chatmongkon Suwannapoom Xing Guo Zhu-Qing Zheng Ali Esmailizadeh Nalini Yasoda Hirimuthugoda Hidayat Ashari Sri Suladari Moch Syamsul Arifin Zein Szilvia Kusza Saeed Sohrabi Hamed Kharrati-Koopaee Quan-Kuan Shen Lin Zeng Min-Min Yang Ya-Jiang Wu Xing-Yan Yang Xue-Mei Lu Xin-Zheng Jia Qing-Hua Nie Susan Joy Lamont Emiliano Lasagna Simone Ceccobelli Humpita Gamaralalage Thilini Nisanka Gunwardana Thilina Madusanka Senasige Shao-Hong Feng Jing-Fang Si Hao Zhang Jie-Qiong Jin Ming-Li Li Yan-Hu Liu Hong-Man Chen Cheng Ma Shan-Shan Dai Abul Kashem Fazlul Haque Bhuiyan Muhammad Sajjad Khan Gamamada Liyanage Lalanie Pradeepa Silva Thi-Thuy Le Okeyo Ally Mwai Mohamed Nawaz Mohamed Ibrahim Megan Supple Beth Shapiro Olivier Hanotte Guojie Zhang Greger Larson Jian-Lin Han Dong-Dong Wu Ya-Ping Zhang | 2020 | Cell Research2020，30，8： | 7 |
| 2 | Multi-targeted therapy of cancer by genistein显示文摘 | Sanjeev Banerjee Yiwei Li Zhiwei Wang Fazlul H. Sarkar | 2008 | Cancer Letters2008，，2： | 3 |
| 3 | Genistein Down-Regulates miR-223 Expression in Pancreatic Cancer Cells显示文摘 | Jia Ma Long Cheng Hao Liu Jing Zhang Ying Shi Fanpeng Zeng Lucio Miele Fazlul H Sarkar Jun Xia Zhiwei Wang | 2013 | Current Drug Targets2013，，10： | 2 |
| 4 | FoxM1 down-regulation leads to inhibition of proliferation, migration and invasion of breast cancer cells through the modulation of extra-cellular matrix degrading factors显示文摘 | Aamir Ahmad Zhiwei Wang Dejuan Kong Shadan Ali Yiwei Li Sanjeev Banerjee Raza Ali Fazlul H. Sarkar | 2010 | Breast Cancer Research and Treatment2010，，2： | 2 |
| 5 | The complexities of obesity and diabetes with the development and progression of pancreatic cancer显示文摘 | Bin Bao Zhiwei Wang Yiwei Li Dejuan Kong Shadan Ali Sanjeev Banerjee Aamir Ahmad Fazlul H. Sarkar | 2010 | BBA - Reviews on Cancer2010，，2： | 2 |
| 6 | Pancreatic cancer stem cells: Emerging target for designing novel therapy显示文摘 | Yiwei Li Dejuan Kong Aamir Ahmad Bin Bao Fazlul H. Sarkar | 2012 | Cancer Letters2012，，： | 2 |
| 7 | Shrinking greenery: Land use and land cover changes in Kurram Agency, Kohi Safid Mountains of north-western Pakistan显示文摘Deforestation and other Land Use and Land Cover(LULC) changes, driven by variety of physical and anthropogenic factors, have altered the mountainous environment. Mountains around the world including northern and north western belts of Pakistan are highly sensitive to deforestation and other LULC changes, which have profound impacts on various sectors of bio-physical and socio-economic systems. Assessment of LULC changes has high significance for protection, conservation and monitoring mountainous environment. The present study is an attempt to assess the landscape changes with particular reference to forest cover depletion in Kurram Agency located in the north western mountain belt of Pakistan. For detailed comparative analysis the study area has been divided into three sections, which coincide with the present administrative divisions of the Agency, i.e., Upper,Lower and Central Kurram. Temporal span of this study covers four decades. In this study, land use map of 1970 and land sat satellite imageries of 1987, 2000 and 2014 were used as spatial data sets. The images were processed and classified into six LULC classes through geospatial packages and change detection maps were prepared for each division and time period.Findings of the study reveal two trends in the four major LULC categories. Forest and rangeland have shrunk, on average, by 15% and 7.5% respectively while, bare soil and rocks outcrops have expanded by 89% and agriculture land by 7.2% in Kurram agency.The water bodies and snow cover have minor fluctuation in its land area. Major causes of shrinking greenery is attributed to high influx of Afghan refugees and high energy demand of growing population. However, with outflow of the refugees from Kurram agency the general trend in forest cover has reverted and deforestation rate has slowed down. | Kamal HUSSAIN Fazlul HAQ Fazlur RAHMAN | 2018 | Journal of Mountain Science2018，15，2： | 2 |
| 8 | Targeting miRNAs involved in cancer stem cell and EMT regulation: An emerging concept in overcoming drug resistance显示文摘 | Zhiwei Wang Yiwei Li Aamir Ahmad Asfar S. Azmi Dejuan Kong Sanjeev Banerjee Fazlul H. Sarkar | 2010 | Drug Resistance Updates2010，，4： | 2 |
| 9 | Over‐expression of FoxM1 leads to epithelial–mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells显示文摘 | Bin Bao Zhiwei Wang Shadan Ali Dejuan Kong Sanjeev Banerjee Aamir Ahmad Yiwei Li Asfar S. Azmi Lucio Miele Fazlul H. Sarkar | 2011 | J Cell Biochem2011，，9： | 2 |
| 10 | Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review显示文摘 | Asfar S. Azmi Bin Bao Fazlul H. Sarkar | 2013 | Cancer and Metastasis Reviews . 2013 (3-4)2013，，3： | 1 |
| 11 | Functional Role of miR-34 Family in Human Cancer显示文摘 | Rui Wang Jia Ma Qiong Wu Jun Xia Lucio Miele Fazlul H Sarkar Zhiwei Wang | 2013 | Current Drug Targets2013，，10： | 1 |
| 12 | Activated K‐Ras and INK4a/Arf deficiency promote aggressiveness of pancreatic cancer by induction of EMT consistent with cancer stem cell phenotype显示文摘 | Zhiwei Wang Shadan Ali Sanjeev Banerjee Bin Bao Yiwei Li Asfar S. Azmi Murray Korc Fazlul H. Sarkar | 2012 | J. Cell. Physiol2012，，3： | 1 |
| 13 | Multi-targeted therapy of cancer by genistein显示文摘 | Sanjeev Banerjee Yiwei Li Zhiwei Wang Fazlul H. Sarkar | 2008 | Cancer Letters2008，，2： | 1 |
| 14 | Simultaneous determination of preservatives (benzoic acid,sorbic acid,methylparaben and propylparaben) in foodstuffs using high-performance liquid chromatography显示文摘 | Bahruddin Saad Md Fazlul Bari | 2005 | Journal of Chromatography A2005，1073，： | 1 |
| 15 | A molecular rheostat at the interface of cancer and diabetes显示文摘 | Mahasin A. Osman Fazlul H. Sarkar Enrique Rodriguez-Boulan | 2013 | BBA - Reviews on Cancer2013，，1： | 1 |
| 16 | Mechanistic studies of hydrocarbon CH/D2 exchange over thermally activated magnesium oxide显示文摘 | Hoq Fazlul M Klabunde K J | 1990 | Journal of Catalysis1990，123，2： | 1 |
| 17 | Molecular alterations associated with improved survival in pancreatic cancer patients treated with radiation or chemotherapy显示文摘 | Sanaa T. Dergham Michael C. Dugan Fazlul H. Sarkar Vainutis K. Vaitkevicius | 1998 | Journal of Hepato - Biliary - Pancreatic Surgery1998，，3： | 1 |
| 18 | The Association Between Selected Risk Factors for Pancreatic Cancer and the Expression of p53 and K-ras Codon 12 Mutations显示文摘 | Jon P. Fryzek David H. Garabrant Maryjean Schenk Margaret Kinnard Joel K. Greenson Fazlul H. Sarkar | 2006 | Journal of Gastrointestinal Cancer2006，，4： | 1 |
| 19 | Fluorocurcumins as Cyclooxygenase-2 Inhibitor: Molecular Docking, Pharmacokinetics and Tissue Distribution in Mice显示文摘 | Subhash Padhye Sanjeev Banerjee Deepak Chavan Shubhangini Pandye K.Venkateswara Swamy Shadan Ali Jing Li Q. Ping Dou Fazlul H. Sarkar | 2009 | Pharmaceutical Research2009，，11： | 1 |
| 20 | Patterns of Loss of Heterozygosity at 10q23.3 and Microsatellite Instability in Endometriosis, Atypical Endometriosis, and Ovarian Carcinoma Arising in Association With Endometriosis显示文摘 | Rouba Ali-Fehmi Ibrahim Khalifeh Sudeshna Bandyopadhyay W. Dwayne Lawrence Elvio Silva Dezhong Liao Fazlul H. Sarkar Adnan R. Munkarah | 2006 | International Journal of Gynecological Pathology2006，，3： | 1 |
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