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| 1 | Novel Ag nanocrystals based dental resin composites with enhanced mechanical and antibacterial properties显示文摘The aim of this work was to investigate the effect of trace addition of oleic acid coated Ag nanocrystals(Ag NCs) on mechanical and antibacterial properties of dental resin composites.Composites(70 wt%of silica loading) with 25 ppm,50 ppm,75 ppm and 100 ppm(wt) Ag NCs were prepared and the composite without Ag NCs served as a control.The experimental results showed that the addition of Ag NCs significantly improved the strength and modulus of the resin composite without compromising the shade.For the composite with 50 ppm Ag NCs,fiexural strength(140.3 MPa),modulus(13.2 GPa)and compressive strength(347.2 MPa) were increased by 4.1%,22.2%,13.3%,respectively,compared with the control.The antibacterial test demonstrated that trace Ag NCs provided the resin composites with an antibacterial effect.Such strong and antibacterial dental resin composites might be advantageous to prevent secondary caries and be potential for future clinical applications. | Fengwei Liu Ruili Wang Yuyuan Shi Xiaoze Jiang Bin Sun Meifang Zhu | 2013 | Progress in Natural Science:Materials International2013，23，6： | 5 |
| 2 | 120 mm Single-crystalline perovskite and wafers: towards viable applications显示文摘As the large single-crystalline silicon wafers have revolutionized many industries including electronics and solar cells, it is envisioned that the availability of large single-crystalline perovskite crystals and wafers will revolutionize its broad applications in photovoltaics, optoelectronics, lasers, photodetectors, light emitting diodes(LEDs), etc. Here we report a method to grow large single-crystalline perovskites including single-halide crystals: CH3NH3PbX3(X=I, Br, Cl), and dual-halide ones:CH3NH3Pb(ClxBr1.x)3 and CH3NH3Pb(BrxI1.x)3, with the largest crystal being 120 mm in length. Meanwhile, we have advanced a process to slice the large perovskite crystals into thin wafers. It is found that the wafers exhibit remarkable features:(1)its trap-state density is a million times smaller than that in the microcrystalline perovskite thin films(MPTF);(2) its carrier mobility is 410 times higher than its most popular organic counterpart P3HT;(3) its optical absorption is expanded to as high as910 nm comparing to 797 nm for the MPTF;(4) while MPTF decomposes at 150 °C, the wafer is stable at high temperature up to270 °C;(5) when exposed to high humidity(75% RH), MPTF decomposes in 5 h while the wafer shows no change for overnight;(6) its photocurrent response is 250 times higher than its MPTF counterpart. A few electronic devices have been fabricated using the crystalline wafers. Among them, the Hall test gives low carrier concentration with high mobility. The trap-state density is measured much lower than common semiconductors. Moreover, the large SC-wafer is found particularly useful for mass production of integrated circuits. By adjusting the halide composition, both the optical absorption and the light emission can be fine-tuned across the entire visible spectrum from 400 nm to 800 nm. It is envisioned that a range of visible lasers and LEDs may be developed using the dual-halide perovskites. With fewer trap states, high mobility, broader absorption, and humidity resistance, it is expected that solar cells with high stable efficiency maybe attainable using the crystalline wafers. | Yucheng Liu Xiaodong Ren Jing Zhang Zhou Yang Dong Yang Fengyang Yu Jiankun Sun Changming Zhao Zhun Yao Bo Wang Qingbo Wei Fengwei Xiao Haibo Fan Hao Deng Liangping Deng Shengzhong (Frank) Liu | 2017 | Science China Chemistry2017，60，10： | 5 |
| 3 | Efficient structural seismic performance evaluation method using improved endurance time analysis显示文摘Evaluation of structural performance under seismic excitations from low intensity to high intensity is essential to verify the seismic resistant capacity of a structure, and usually carried out by the incremental dynamic analysis (IDA) method or pushover method. The recently developed endurance time (ET) method is another method that uses dynamic pushover excitations, i.e., endurance time acceleration function, to obtain results similar to those obtained by IDA or pushover methods with low computational cost and acceptable accuracy. This study proposes an improvement on the ET method by considering more restrictions for both the elastic and inelastic response spectra in the generation procedure, and by specifying a target duration. Four reinforced concrete frame structures with 4, 8, 12, and 16 stories are adopted to verify the accuracy of the improved method. Comparison of the results obtained by the proposed method, the ET method and the IDA method shows that the improved method has a higher accuracy than the ET method. For evaluation of structural responses under specifi c ground motion intensity, which is typically required in seismic design codes, the results obtained by the proposed method are compared with fi ve commonly used ground motion selection methods, and shows the proposed method provides acceptable accuracy for engineering applications. | Li Shuang Liu Kun Liu Xiangyang Zhai Changhai Xie Fengwei | 2019 | Earthquake Engineering and Engineering Vibration2019，18，4： | 3 |
| 4 | A temperature responsive adhesive hydrogel for fabrication of flexible electronic sensors显示文摘Flexible electronics are playing an increasingly important role in human health monitoring and healthcare diagnosis.Strong adhesion on human tissue would be ideal for reducing interface resistance and motion artifacts,but arising problems such as skin irritation,rubefaction,and pain upon device removal have hampered their utility.Here,inspired by the temperature reversibility of hydrogen bonding,a skin-friendly conductive hydrogel with multiple-hydrogen bonds was designed by using biocompatible poly(vinyl alcohol)(PVA),phytic acid(PA),and gelatin(Gel).The obtained PVA/PA/Gel(PPG)hydrogel with temperature-triggered tunable mechanic could reliably adhere to skin and detect electrophysiological signals under a hot compress while be readily removed under a cool compress.Furthermore,the additional advantages of transparency,breathability,and antimicrobial activity of the PPG hydrogel ensure its long-time wearable value on the skin.It is both environmentally friendly and cost saving for the waste PPG hydrogel during production can be recycled based on their reversible physical bonding.The PPG hydrogel sensor is expected to have good application prospects to record electrophysiological signals in human health monitoring. | Wan Liu Ruijie Xie Jingyu Zhu Jiansheng Wu Junfeng Hui Xiaoyan Zheng Fengwei Huo Daidi Fan | 2022 | npj Flexible Electronics2022，6，1： | 2 |
| 5 | Lactobacillus plantarum CCFM8610 Alleviates Irritable Bowel Syndrome and Prevents Gut Microbiota Dysbiosis:A Randomized,Double-Blind,Placebo-Controlled,Pilot Clinical Trial显示文摘Irritable bowel syndrome with diarrhea(IBS-D)is chronic intestinal dysfunction with diarrhea and othercomplicated clinical symptoms,and it has a great impact on the daily life and mental state of patients.Some studies have reported that ingestion of probiotics can significantly alleviate a variety of intestinaldiseases.The pupose of this study was to investigate the IBS-D-alleviating effects of a probiotic strain,lactobacillus plantarum(L.plantarum)CCFM8610,with multiple health-promoting effects.The studywas a 12-week,randomized,double-blind,placebo-controlled,pilot clinical trial.Seventy-five patientswere randomly assigned to receive the placebo,oligosaccharides,or L.plantarum CCFM8610(1×10^(10) colony-forming units(CFU)per day),with a 2-week run-in period,an 8-week intervention period,anda 2-week follow-up observation period.The patients'clinical symptoms and quality of life were exam-ined by the IBS symptom severity scale(IBS-SsS)and the IlBS quality of life scale(IBS-QOL).Changes ingut microbiota composition and diversity were measured at the end of the intervention period.The oraladministration of L.plantarum CCFM8610 significantly decreased the IBS-SSS and IBS-QOL scores,reduced IBS-D symptom severity,recovered gut microbiota diversity,decreased the relative abundanceof bloating-related genus Methanobrevibacter,and increased the relative abundance of butyric acid-producing genera,including Anaerostipes,Anaerotruncus,Bifidobacterium,Butyricimonas,andOdoribacter.These findings suggest that ingestion of L.plantarum CCFM8610 can significantly alleviate clinical symptoms and gut microbiota dysbiosis in IBS-D patients.The IBS-D-alleviating effect of L.plan-tarum CCFM8610 may be related to theincrease in the relative abundance of butyric acid-producing genera in the intestine. | Yang Liu Xinjie Yu Leilei Yu Fengwei Tian Jianxin Zhao Hao Zhang Long Qian Qun Wang Zhengqing Xue Qixiao Zhai Wei Chen | 2021 | Engineering2021，7，3： | 2 |
| 6 | The Class Ⅲ peroxidase gene OsPrx30,transcriptionally modulated by the AT-hook protein OsATH1, mediates rice bacterial blight-induced ROS accumulation显示文摘Class Ⅲ peroxidases(CⅢ Prxs) play critical roles in plant immunity by scavenging reactive oxygen species(ROS). However, the functions of CⅢ Prxs in rice(Oryza sativa L.) immunity are largely unexplored. Here, we report a Prx precursor, OsPrx30,that is responsive to the bacterial blight Xanthomonas oryzae pv. oryzae(Xoo). OsPrx30 was primarily expressed in rice roots, leaves, and stems,and its protein product was mainly localized at the endoplasmic reticulum. Overexpression of OsPrx30 enhanced the plant’s susceptibility to Xoo by maintaining a high level of peroxidase(POD) activity and reducing the content of H2O2, whereas depletion of OsPrx30 had the opposite effects. Furthermore, we identified an AT-hook transcription factor, Os ATH1, that is specifically bound to the OsPrx30 promoter. As observed in plants overexpressing OsPrx30, depletion of Os ATH1 enhanced susceptibility to Xoo. Finally, we demonstrated that depletion of Os ATH1 increased histone H3 acetylation at the AT-rich region of the OsPrx30 promoter.Taken together, these results reveal a mechanism underlying the POD-induced natural resistance to bacterial diseases and suggest a model for transcription regulation of Prx genes in rice. | Hao Liu Shuangyu Dong Ming Li Fengwei Gu Guili Yang Tao Guo Zhiqiang Chen Jiafeng Wang | 2021 | Journal of Integrative Plant Biology2021，63，2： | 2 |
| 7 | Orthogonal projection based subspace identification against colored noise显示文摘在这份报纸,一个消除偏爱的 subspace 鉴定方法为易于的工业应用被建议给噪音涂颜色。基于两倍直角的设计,一个鉴定算法被开发为植物的扩大 observability 矩阵的一致评价消除有颜色的噪音的影响州空间的模型。一条移动不变的途径然后被给从估计的扩大 observability 矩阵检索系统矩阵。为扩大 observability 矩阵的一致评价的坚持的刺激条件被分析。而且,一个数字算法被给计算估计的扩大 observability 矩阵的评价错误。二个解说性的例子被给表明建议方法的有效性和优点。 | Jie HOU Tao LIU Fengwei CHEN | 2017 | Control Theory and Technology2017，15，1： | 1 |
| 8 | Screening of lactobacilli with antagonistic activity against enteroinvasive Escherichia coli显示文摘 | Xiaoming Liu Wenyu Liu Qiuxiang Zhang Fengwei Tian Gang Wang Hao Zhang Wei Chen | 2013 | Food Control2013，，2： | 1 |
| 9 | Gelatinization of cornstarch with different amylase/amylopectin content 显示文摘 | Hongsheng Liu Long Yu Fengwei Xie | 2006 | Carbohydrate Polymers2006，65，3： | 1 |
| 10 | Gelatinization of cornstarch with different amylose/amylopectin content显示文摘 | Hongsheng Liu Long Yu Fengwei Xie Ling Chen | 2006 | Carbohydrate Polymers2006，，3： | 1 |
| 11 | Thermal processing of starch based polymers 显示文摘 | Liu Hongsheng Xie Fengwei Yu Long | 2009 | Progress in Polymer Sci- ence2009，34，12： | 1 |
| 12 | A review of sampling,energy supply and intelligent monitoring for long-term sweat sensors显示文摘Sweat is a biofluid with rich information that can reflect an individual’s state of health or activity.But the real-time in situ sweat sensors lack the ability of long-term monitoring.Against this background,this article provides a holistic review on the necessary process and methods for sweat sensing,including sweat collection,composition analysis,energy supply,and data processing.The impacts of the environment in stimulating sweat production,providing energy supply,and intelligent health monitoring are discussed.Based on the review of previous endeavors,the future development in material,structure and artificial intelligence application of long-term sweat monitoring is envisioned. | Pufan Yang Gaofeng Wei Ang Liu Fengwei Huo Zhinan Zhang | 2022 | npj Flexible Electronics2022，6，1： | 1 |
| 13 | Biological Characteristics of Aeromonas Strains in Nanchang Area显示文摘[Objectives]This study was conducted to find effective measures to prevent and control Pelteobagrus fulvidraco hemorrhage.[Methods]Typical disease materials were collected for bacterial isolation and culture and biological characteristics detection,and morphological characteristics were observed by pure culture method.Biochemical characteristics were identified by micro biochemical method.Molecular identification was performed by PCR amplification method.Drug resistance was detected by disk diffusion method.The agar diffusion method was used for the detection of in-vitro inhibitory effect.The immunogenicity of the isolates was detected by subcutaneous immunoassay.The virulence factor was detected by spot inoculation.The intraperitoneal injection was used for the detection of pathogenicity.[Results]The isolates were round,grayish white,and identified as Aeromonas.They fermented maltose,glucose,etc.,did not ferment lactose,and were negative for urea and H2S and positive for lysine and arginine.The target fragment appeared at 1 500,and the sequences shared the highest homology with Aeromonas.The isolates were highly susceptible to amikacin and gentamicin,and resistant to penicillin G and tetracycline.Eight lactic acid bacteria strains produced 1.1-1.9 cm of inhibition zone against the isolates.After the second vaccination,the titer reached 2^13;both hemolysin and protease were produced;and the test mice died within 24 h.[Conclusions]The isolates are Aeromonas,and have strong drug resistance,immunogenicity and pathogenicity.Inactivated emusion-oil vaccines of Aeromonas combined with the co-use of lactic acid bacteria and susceptible drugs can prevent the outbreak of diseases caused by Aeromonas. | Xinyi SHAN Dongxu WEN Xiaolan LIU Wangming TAO Mengjuan ZHANG Wei QI Fengwei ZHANG Zhixiu ZHU | 2019 | Agricultural Biotechnology2019，8，3： | 1 |
| 14 | Lactobacillus plantarum CCFM8661 Alleviates Lead Toxicity in Mice显示文摘 | Fengwei Tian Qixiao Zhai Jianxin Zhao Xiaoming Liu Gang Wang Hao Zhang Heping Zhang Wei Chen | 2012 | Biological Trace Element Research2012，，1： | 1 |
| 15 | Thermal Processing of Starch-based Polymers显示文摘 | Hongsheng Liu Fengwei Xie Long Yua | 2009 | Progress in Polymer Science2009，34，： | 1 |
| 16 | Gelatinization of cornstarch with different amylose/amylopectin content显示文摘 | Hongsheng Liu Long Yu Fengwei Xie Ling Chen | 2006 | Carbohydrate Polymers2006，，3： | 1 |
| 17 | Assembly process and source tracking of microbial communities in sediments of Dongting Lake显示文摘●Soil erosion resulted in homogenization of bacterial communities in the watershed.●Microbial community heterogeneity among erosion sites made soil tracing possible.●Assembly process results showed that the tracking results can achieve high precision.●Dryland was the main source of sediment deposition based on the result of FEAST.Sediment source tracing can accurately provide a theoretical basis for controlling soil erosion effectively,by identifying the most serious types of land use.Traditional sediment tracing methods are based on physical,chemical,biological,and composite fingerprinting,which have not included microbes.As high-throughput sequencing becomes more prevalent,microorganisms can provide more information than what we think.Thus,whether the microorganism can also be used as a special fingerprint factor for sediment source identification during soil erosion,we have tested it by using microbial source tracking tool FEAST to quantify the microbe contribution from five types of eroded land(including dryland,urban,paddy field,forest and grassland)to the depositional areas(Niubitan)in the Yuanjiang basin.The source microbial community in the erosive area was heterogeneous,and assembly process analysis further demonstrated that the source tracking results could reach higher accuracy.The results of FEAST showed that dryland(35.50%),urban(17.21%),paddy field(8.14%),and forest(1.07%)were the major contributors to Niubitan.Our results follow the general soil erosion rules and prove its validity.Taken together,a new perspective is provided by these results for tracing sediment sources in erosion-sedimentary systems. | Wenfei Liao Di Tong Xiaodong Nie Yaojun Liu Fengwei Ran Shanshan Liao Jia Chen Aoqi Zeng Zhongwu Li | 2023 | Soil Ecology Letters2023，5，4： | 1 |
| 18 | Thermal processing of starch-based polymers 显示文摘 | Hongsheng Liu Fengwei Xie Long Yu | 2009 | Progress in Polymer Science2009，34，12： | 1 |
| 19 | Identification of A-to-I RNA editing profiles and their clinical relevance in lung adenocarcinoma显示文摘Adenosine-to-inosine(A-to-I)RNA editing is a widespread posttranscriptional modification that has been shown to play an important role in tumorigenesis.Here,we evaluated a total of 19,316 RNA editing sites in the tissues of 80 lung adenocarcinoma(LUAD)patients from our Nanjing Lung Cancer Cohort(NJLCC)and 486 LUAD patients from the TCGA database.The global RNA editing level was significantly increased in tumor tissues and was highly heterogeneous across patients.The high RNA editing level in tumors was attributed to both RNA(ADAR1 expression)and DNA alterations(mutation load).Consensus clustering on RNA editing sites revealed a new molecular subtype(EC3)that was associated with the poorest prognosis of LUAD patients.Importantly,the new classification was independent of classic molecular subtypes based on gene expression or DNA methylation.We further proposed a simplified model including eight RNA editing sites to accurately distinguish the EC3 subtype in our patients.The model was further validated in the TCGA dataset and had an area under the curve(AUC)of the receiver operating characteristic curve of 0.93(95%CI:0.91-0.95).In addition,we found that LUAD cell lines with the EC3 subtype were sensitive to four chemotherapy drugs.These findings highlighted the importance of RNA editing events in the tumorigenesis of LUAD and provided insight into the application of RNA editing in the molecular subtyping and clinical treatment of cancer. | Cheng Wang Mingtao Huang Congcong Chen Yuancheng Li Na Qin Zijian Ma Jingyi Fan Linnan Gong Hui Zeng Liu Yang Xianfeng Xu Jun Zhou Juncheng Dai Guangfu Jin Zhibin Hu Hongxia Ma Fengwei Tan Hongbing Shen | 2022 | Science China(Life Sciences)2022，65，1： | 1 |
| 20 | Seroprevalence of influenza viruses in Shandong,Northern China during the COVID-19 pandemic显示文摘Nonpharmaceutical interventions(NPIs)have been commonly deployed to prevent and control the spread of the coronavirus disease 2019(COVID-19),resulting in a worldwide decline in influenza prevalence.However,the influenza risk in China warrants cautious assessment.We conducted a cross-sectional,seroepidemiological study in Shandong Province,Northern China in mid-2021.Hemagglutination inhibition was performed to test antibodies against four influenza vaccine strains.A combination of descriptive and meta-analyses was adopted to compare the seroprevalence of influenza antibodies before and during the COVID-19 pandemic.The overall seroprevalence values against A/H1N1pdm09,A/H3N2,B/Victoria,and B/Yamagata were 17.8%(95%CI 16.2%–19.5%),23.5%(95%CI 21.7%–25.4%),7.6%(95%CI 6.6%–8.7%),and 15.0(95%CI 13.5%–16.5%),respectively,in the study period.The overall vaccination rate was extremely low(2.6%).Our results revealed that antibody titers in vaccinated participants were significantly higher than those in unvaccinated individuals(P<0.001).Notably,the meta-analysis showed that antibodies against A/H1N1pdm09 and A/H3N2 were significantly low in adults after the COVID-19 pandemic(P<0.01).Increasing vaccination rates and maintaining NPIs are recommended to prevent an elevated influenza risk in China. | Chuansong Quan Zhenjie Zhang Guoyong Ding Fengwei Sun Hengxia Zhao Qinghua Liu Chuanmin Ma Jing Wang Liang Wang Wenbo Zhao Jinjie He Yu Wang Qian He Michael J.Carr Dayan Wang Qiang Xiao Weifeng Shi | 2022 | Frontiers of Medicine2022，16，6： | 1 |
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