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| 1 | 肺癌筛查检出的肺结节特征对于半自动体积测量的差异性的影响显示文摘目的回顾性地评价肺癌筛查中发现的实性肺结节体积测量的差异性,定量分析肺结节的形态、大小和位置的各自影响作用。方法此研究是肺癌筛查中的一个分项研究,经德国卫生部批准,所有受试者都签署了知情同意书。2位评价者分别应用半自动软件测量了6774受试者(年龄50~75岁,男5917例)的肺内结节。根据结节所在位置将结节分为完全肺实质型、胸膜基底型、血管旁型和叶间裂旁型:按照外形分为光滑、分叶状、毛刺状和不规则形状: | Y. Wang R. Klaveren H. Zaag-Loonen G. Bock H. Gietema D. Xu 高莉(译) 唐光健(校) | 2008 | 国际医学放射学杂志2008，31，5： | 5 |
| 2 | Connexin32 hemichannels contribute to the apoptotic-to-necrotic transition during Fas-mediated hepatocyte cell death显示文摘 | Mathieu Vinken Elke Decrock Elke Vuyst Marijke Bock Roosmarijn E. Vandenbroucke Bruno G. Geest Joseph Demeester Niek N. Sanders Tamara Vanhaecke Luc Leybaert Vera Rogiers | 2010 | Cellular and Molecular Life Sciences2010，，6： | 2 |
| 3 | Toxicity and survival in primary glioblastoma patients treated with concomitant plus adjuvant temozolomide versus adjuvant temozolomide: results of a single-institution, retrospective, matched-pair analysis显示文摘 | A. Gutenberg H. C. Bock G. Reifenberger W. Brück A. Giese | 2013 | Acta Neurochirurgica2013，，3： | 2 |
| 4 | Engineering glutathione transferase to a novel glutathione peroxidase mimic with high catalytic efficiency - Incorporation of selenocysteine into a glutathione-binding scaffold using an auxotrophic expression system显示文摘 | Yu, H. J. Liu, J. Q. Bock, A. Li, J. Luo, G. M. Shen, J. C. | 2007 | 中国生物学文摘2007，21，2： | 2 |
| 5 | The potential of Bacillus licheniformis strains for in situ enhanced oil recovery显示文摘 | Michail M. Yakimov Mohammed M. Amro Michael Bock Klaus Boseker Herbert L. Fredrickson Dagobert G. Kessel Kenneth N. Timmis | 1997 | Journal of Petroleum Science and Engineering1997，，1： | 1 |
| 6 | The next-generation sphingosine-1 receptor modulator BAF312(siponimod) improves cortical network functionality in focal autoimmune encephalomyelitis显示文摘Autoimmune diseases of the central nervous system(CNS) like multiple sclerosis(MS) are characterized by inflammation and demyelinated lesions in white and grey matter regions. While inflammation is present at all stages of MS, it is more pronounced in the relapsing forms of the disease, whereas progressive MS(PMS) shows significant neuroaxonal damage and grey and white matter atrophy. Hence, disease-modifying treatments beneficial in patients with relapsing MS have limited success in PMS. BAF312(siponimod) is a novel sphingosine-1-phosphate receptor modulator shown to delay progression in PMS. Besides reducing inflammation by sequestering lymphocytes in lymphoid tissues, BAF312 crosses the blood-brain barrier and binds its receptors on neurons, astrocytes and oligodendrocytes. To evaluate potential direct neuroprotective effects, BAF312 was systemically or locally administered in the CNS of experimental autoimmune encephalomyelitis mice with distinct grey-and white-matter lesions(focal experimental autoimmune encephalomyelitis using an osmotic mini-pump). Ex-vivo flow cytometry revealed that systemic but not local BAF312 administration lowered immune cell infiltration in animals with both grey and white matter lesions. Ex-vivo voltage-sensitive dye imaging of acute brain slices revealed an altered spatio-temporal pattern of activation in the lesioned cortex compared to controls in response to electrical stimulation of incoming white-matter fiber tracts. Here, BAF312 administration showed partial restore of cortical neuronal circuit function. The data suggest that BAF312 exerts a neuroprotective effect after crossing the blood-brain barrier independently of peripheral effects on immune cells. Experiments were carried out in accordance with German and EU animal protection law and approved by local authorities(Landesamt für Natur, Umwelt und Verbraucherschutz Nordrhein-Westfalen;87-51.04.2010.A331) on December 28, 2010. | Petra Hundehege Manuela Cerina Susann Eichler Christian Thomas Alexander M. Herrmann Kerstin Goel Thomas Müntefering Juncal Fernandez-Orth Stefanie Bock Venu Narayanan Thomas Budde Erwin-Josef Speckmann Heinz Wiendl Anna Schubart Tobias Ruck Sven G. Meuth | 2019 | Neural Regeneration Research2019，14，11： | 1 |
| 7 | Diagnostic Performance of Cardiovascular Magnetic Resonance in Patients With Suspected Acute Myocarditis显示文摘 | Hassan Abdel-Aty Philipp Boyé Anja Zagrosek Ralf Wassmuth Andreas Kumar Daniel Messroghli Petra Bock Rainer Dietz Matthias G. Friedrich Jeanette Schulz-Menger | 2005 | Journal of the American College of Cardiology2005，，11： | 1 |
| 8 | Serum cytokine profiles associated with clinical presentation in Vietnamese infected with hepatitis B virus显示文摘 | Le H. Song Vu Q. Binh Dinh N. Duy Jürgen F.J. Kun Thomas C. Bock Peter G. Kremsner Adrian J.F. Luty | 2002 | Journal of Clinical Virology2002，，1： | 1 |
| 9 | Strange particle production in nuclear collisions at 200 GeV per nucleon显示文摘 | T. Alber H. Appelsh?user J. B?chler J. Bartke H. Bia?kowska M. A. Bloomer R. Bock W. J. Braithwaite D. Brinkmann R. Brockmann P. Bun?i? P. Chan S. I. Chase J. G. Cramer P. B. Cramer I. Derado V. Eckardt J. Eschke C. Favuzzi D. Ferenc B. Fleischmann P. Fok | 1994 | Zeitschrift für Physik C Particles and Fields1994，，2： | 1 |
| 10 | Adenovirus vector-mediated RNA interference for the inhibition of human parvovirus B19 replication显示文摘 | Marius R.G. Brandt Ariane G. Kirste Tanja Pozzuto Steffen Schubert Reinhard Kandolf Henry Fechner C.-Thomas Bock Jens Kurreck | 2013 | Virus Research2013，，： | 1 |
| 11 | Long-term evaluation of a structured outpatient education programme for intensified insulin therapy in patients with Type 1 diabetes: a 12-year follow-up显示文摘 | J. Plank G. K?hler I. Rakovac B. M. Semlitsch K. Horvath G. Bock B. Kraly T. R. Pieber | 2004 | Diabetologia2004，，8： | 1 |
| 12 | High-rate GPS clock corrections from CODE: support of 1?Hz applications显示文摘 | H. Bock R. Dach A. J?ggi G. Beutler | 2009 | Journal of Geodesy2009，，11： | 1 |
| 13 | The clinical value of a negative multi-detector computed tomographic angiography in patients suspected of coronary artery disease: a meta-analysis显示文摘 | H. J. Zaag-Loonen R. Dikkers G. H. Bock M. Oudkerk | 2006 | European Radiology2006，，12： | 1 |
| 14 | Phase center modeling for LEO GPS receiver antennas and its impact on precise orbit determination显示文摘 | Adrian J?ggi R. Dach O. Montenbruck U. Hugentobler H. Bock G. Beutler | 2009 | Journal of Geodesy2009，，12： | 1 |
| 15 | p53 REEPs to sow ER-mitochondrial contacts显示文摘 | Florian J. Bock Stephen W. G. Tait | 2018 | Cell Research2018，28，9： | 0 |
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