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| 1 | Bio-leaching effects of Leptospirillum ferriphilum on the surface chemical properties of pyrite显示文摘Leptospirillum ferriphilum cultured using different energy sources(either soluble ferrous ion or pyrite) changed the surface properties of pyrite.Cell adsorption,zeta-potential,hydrophobicty,FT-IR spectra and surface morphology were investigated.Adhesion of bacterial cells to the pyrite surface is a fast process.Furthermore,the adsorption of cells grown in pyrite is greater than of cells grown in soluble ferrous ion.The Iso-Electric Point(IEP) of pyrite treated with L.ferriphilum approaches that of the cells themselves.The contact angle of the pyrite surface was observed to decrease due to the surface formation of some hydrophilic substances during bio-leaching.Changes in pyrite surface properties after bacterial treatment support the idea that ferric ion plays an important role and that indirect bio-oxidation is the principal mechanism of pyrite bio-leaching. | GU, Guohua SU, Lijun CHEN, Minglian SUN, Xiaojun ZHOU, Hongbo | 2010 | Mining Science and Technology2010，20，2： | 14 |
| 2 | Application of next-generation sequencing technology to precision medicine in cancer: joint consensus of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology显示文摘Next-generation sequencing(NGS) technology is capable of sequencing millions or billions of DNA molecules simultaneously.Therefore, it represents a promising tool for the analysis of molecular targets for the initial diagnosis of disease, monitoring of disease progression, and identifying the mechanism of drug resistance. On behalf of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology(CSCO) and the China Actionable Genome Consortium(CAGC), the present expert group hereby proposes advisory guidelines on clinical applications of NGS technology for the analysis of cancer driver genes for precision cancer therapy. This group comprises an assembly of laboratory cancer geneticists, clinical oncologists, bioinformaticians,pathologists, and other professionals. After multiple rounds of discussions and revisions, the expert group has reached a preliminary consensus on the need of NGS in clinical diagnosis, its regulation, and compliance standards in clinical sample collection. Moreover, it has prepared NGS criteria, the sequencing standard operation procedure(SOP), data analysis, report, and NGS platform certification and validation. | Xuchao Zhang Zhiyong Liang Shengyue Wang Shun Lu Yong Song Ying Cheng Jianming Ying Weiping Liu Yingyong Hou Yangqiu Li Yi Liu Jun Hou Xiufeng Liu Jianyong Shao Yanhong Tai Zheng Wang Li Fu Hui Li Xiaojun Zhou Hua Bai Mengzhao Wang You Lu Jinji Yang Wenzhao Zhong Qing Zhou Xuening Yang Jie Wang Cheng Huang Xiaoqing Liu Xiaoyan Zhou Shirong Zhang Hongxia Tian Yu Chen Ruibao Ren Ning Liao Chunyan Wu Zhongzheng Zhu Hongming Pan Yanhong Gu Liwei Wang Yunpeng Liu Suzhan Zhang Tianshu Liu Gong Chen Zhimin Shao Binghe Xu Qingyuan Zhang Ruihua Xu Lin Shen Yilong Wu | 2019 | Cancer Biology & Medicine2019，16，1： | 14 |
| 3 | Basic performance of BeiDou-2 navigation satellite system used in LEO satellites precise orbit determination显示文摘The visibility for low earth orbit(LEO) satellites provided by the BeiDou-2 system is analyzed and compared with the global positioning system(GPS). In addition, the spaceborne receivers' observations are simulated by the BeiDou satellites broadcast ephemeris and LEO satellites orbits. The precise orbit determination(POD) results show that the along-track component accuracy is much better over the service area than the non-service area, while the accuracy of the other two directions keeps at the same level over different areas. However, the 3-dimensional(3D) accuracy over the two areas shows almost no difference. Only taking into consideration the observation noise and navigation satellite ephemeris errors, the 3D accuracy of the POD is about30 cm. As for the precise relative orbit determination(PROD), the 3D accuracy is much better over the eastern hemisphere than that of the western hemisphere. The baseline length accuracy is 3.4 mm over the service area, and it is still better than 1 cm over the non-service area. This paper demonstrates that the BeiDou regional constellation could provide global service to LEO satellites for the POD and the PROD. Finally, the benefit of geostationary earth orbit(GEO) satellites is illustrated for POD. | Liu Junhong Gu Defeng Ju Bing Yao Jing Duan Xiaojun Yi Dongyun | 2014 | Chinese Journal of Aeronautics2014，27，5： | 9 |
| 4 | First light of the 1.8-m solar telescope–CLST显示文摘Large-aperture solar telescopes play an important role in solar observations and research,and require high temporal and spatial resolution[1].To solve some fundamental problems such as the solar dynamo,coronal heating,and the triggering of major solar eruptions,the spatial resolution for solar-atmosphere observation should reach at least 0.1 arcsec[2]. | ChangHui Rao NaiTing Gu XueJun Rao Cheng Li LanQiang Zhang JinLong Huang Lin Kong Ming Zhang YunTao Cheng Yi Pu Hua Bao YouMing Guo YangYi Liu JinSheng Yang LiBo Zhong ChangJun Wang Kai Fang XiaoJun Zhang DongHong Chen Cheng Wang XinLong Fan ZhiWu Yan KeLe Chen XiYa Wei Lei Zhu Hong Liu YongJian Wan Hao Xian WenLi Ma | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，10： | 6 |
| 5 | Photocatalytic degradation of phenanthrene on soil surfaces in the presence of nanometer anatase TiO_2 under UV-light显示文摘The effect of nanometer anatase TiO2 was investigated on the photocatalytic degradation of phenanthrene on soil surfaces under a variety of conditions.After being spiked with phenanthrene,soil samples loaded with different amounts of TiO2(0wt.%,1wt.%,2wt.%,3wt.%,and 4 wt.%) were exposed to UV-light irradiation for 25 hr.The results indicated that the photocatalytic degradation of phenanthrene followed the pseudo first-order kinetics.TiO2 significantly accelerated the degradation of phenanthrene with the half-life reduced from 45.90 to 31.36hr for TiO2 loading of 0wt.% and 4wt.%,respectively.In addition,the effects of H2O2,light intensity and humic acid on the degradation of phenanthrene were investigated.The degradation of phenanthrene increased with the concentration of H2O2,light intensity and the concentration of humic acids.It has been demonstrated that the photocatalytic method in the presence of nanometer anatase TiO2 was a very promising technology for the treatments of soil polluted with organic substances in the future. | Jiali Gu Dianbo Dong Lingxue Kong Yong Zheng Xiaojun Li | 2012 | Journal of Environmental Sciences2012，24，12： | 5 |
| 6 | Phosphine production in anaerobic wastewater treatment under tetracycline antibiotic pressure显示文摘The influence of tetracycline(TC) antibiotics on phosphine(PH_3) production in the anaerobic wastewater treatment was studied. A lab-scale anaerobic baffled reactor with three compartments was employed to simulate this process. The reactor was operated in a TC-absence wastewater and 250 μg/L TC-presence wastewater for three months after a start-up period,respectively. The responses of p H, oxidation–reduction potential(ORP), chemical oxygen demand(COD), total phosphorus(TP), enzymes activity(dehydrogenase and acid phosphatase),and microbial community were investigated to reveal the effect of TC on PH_3 production.Results suggested that the dehydrogenase(DH) activity, acid phosphatase(ACP) activity and COD have positive relationship with PH_3 production, while p H, ORP level and the TP in liquid phase have negative relationship with PH_3 production. With prolonged TC exposure, decrease in p H and increase in DH activity are beneficial to PH_3 production, while decrease in COD and ACP activity are not the limiting factors for PH_3 production. | Meiqing Lu Xiaojun Niu Weiyi Chen Zhu Liang Sheng You Xiaohong Gu | 2018 | Journal of Environmental Sciences2018，30，7： | 5 |
| 7 | Integrated optimization design of smart morphing wing for accurate shape control显示文摘Smart morphing wing, which is equipped with smart materials and able to change structural geometry adaptively, can further improve aerodynamic efficiency of aircraft. This paper presents a new integrated layout and topology optimization design for morphing wing driven by shape memory alloys(SMAs). By simultaneously optimizing the layout of smart actuators and topology of wing substrate, the ultimately determined configuration can achieve smooth, continuous and accurate geometric shape changes. In addition, aerodynamic analysis is carried out to compare smart morphing wing with traditional hinged airfoil. Finally, the optimized smart wing structure is constructed and tested to demonstrate and verify the morphing functionality. Application setbacks are also pointed out for further investigation. | Xiaojun GU Kaike YANG Manqiao WU Yahui ZHANG Jihong ZHU Weihong ZHANG | 2021 | Chinese Journal of Aeronautics2021，34，1： | 5 |
| 8 | Precise output loads control of load-diffusion components with topology optimization显示文摘The purpose of this paper is to present a novel topology optimization approach to control precisely the output loads under static loads and harmonic excitations.We introduce the Artificial Bar Element(ABE)at the designated output positions,where the output loads are equivalently measured and constrained with the nodal displacements of ABE.Optimization model is then formulated considering the output load constraints as well as the minimization of strain energy and dynamic displacement responses respectively under the static and dynamic conditions.The influences of the ABEs stiffness,different material usages of the design domain,widths of the output loads constraint intervals and variation ratios of output loads are discussed in detail.The proposed method is verified with several numerical examples with clear and reasonable load transfer paths. | Yinfeng CAO Xiaojun GU Jihong ZHU Weihong ZHANG | 2020 | Chinese Journal of Aeronautics2020，33，3： | 5 |
| 9 | Longitudinal Alterations of Local Spontaneous Brain Activity in Parkinson's Disease显示文摘We used resting-state fMRI to evaluate longitudinal alterations in local spontaneous brain activity in Parkinson's disease(PD) over a 2-year period. Data were acquired from 23 PD patients at baseline and follow-up,and 27 age-and sex-matched normal controls. Regional homogeneity(ReHo) and voxel-based-morphometry(VBM) were used to identify differences in local spontaneous brain activity and grey matter volume. With disease progression, we observed a progressive decrease in ReHo in the sensorimotor cortex, default-mode network, and left cerebellum, but increased ReHo in the supplementary motor area, bilateral temporal gyrus, and hippocampus.Moreover, there was a significant positive correlation between the rates of ReHo change in the left cerebellum and the rates of change in the Unified Parkinson's Disease Rating Scale-III scores. VBM revealed no significant differences in the grey matter volume among the three sets of acquisitions. We conclude that ReHo may be a suitable non-invasive marker of progression in PD. | Qiaoling Zeng Xiaojun Guan Jason C.F.Law Yan Lun Zhujing Shen Tao Guo Min Xuan Quanquan Gu Xiaojun Xu Min Chen Minming Zhang | 2017 | Neuroscience Bulletin2017，33，5： | 4 |
| 10 | Ultra-stable super-resolution fluorescence cryo-microscopy for correlative light and electron cryo-microscopy显示文摘Remarkable progress in correlative light and electron cryo-microscopy(cryo-CLEM) has been made in the past decade. A crucial component for cryo-CLEM is a dedicated cryo-fluorescence microscope(cryo-FM). Here, we describe an ultra-stable superresolution cryo-FM that exhibits excellent thermal and mechanical stability. The temperature fluctuations in 10 h are less than0.06 K, and the mechanical drift over 5 h is less than 200 nm in three dimensions. We have demonstrated the super-resolution imaging capability of this system(average single molecule localization accuracy of ~13.0 nm). The results suggest that our system is particularly suitable for long-term observations, such as single molecule localization microscopy(SMLM) and cryogenic super-resolution correlative light and electron microscopy(csCLEM). | Xiaojun Xu Yanhong Xue Buyun Tian Fengping Feng Lusheng Gu Weixing Li Wei Ji Tao Xu | 2018 | Science China(Life Sciences)2018，61，11： | 3 |
| 11 | Treatment of acid rose dye containing wastewater by ozonizing – biological aerated filter显示文摘 | Xiaojun Wang Xiaoyang Gu Dexian Lin Fang Dong Xiaofang Wan | 2006 | Dyes and Pigments2006，，3： | 3 |
| 12 | A feasibility study of the measuring accuracy and capability of wireless sensor networks in tunnel monitoring显示文摘Fire disasters and the deterioration of tunnel structures are major concerns for tunnel operation and maintenance.Traditional wired monitoring systems have many drawbacks in terms of installation time,overall cost,and flexibility in tunnel environments.In recent years,there has been growing interest in the use of wireless sensor networks(WSNs)for the monitoring of various structural monitoring applications.This paper evaluated the feasibility of applying a WSN in the monitoring of tunnels.The monitoring requirements of tunnels under explosion and combustion fire scenarios are analyzed using numerical simulation,and the maximum possible distance for temperature sensors is derived.The displacement monitoring of tunnels using an inclinometer is investigated.It is recommended that the inclinometer should be installed in the 1/4 span of the tunnel structure.The maximum wireless transmission distances in both outdoor and tunnel environments were examined.The influences of surface materials and sensor node locations on the data transmission distance in tunnel environments were also investigated.The experimental results show that the data loss in tunnel environments is approximately three times that in outdoor environments.Surface material has a considerable influence on the transmission distance of radio signals.The distance is 25~28 m for a raw concrete surface,20 m for a brick surface,and 36 m for a terrazzo surface.The transmission distances along the middle of quarter points are approximately 0.9D(D is the transmission distance in the center of the tunnel),and the relative error is less than±3%.The transmission distances at different locations along the bottom exhibit significant differences,decreasing from the middle to the comer point,with distances of approximately 0.8D at the quarter points and minimum distances of approximately 0.55D at the comer points. | Xiaojun LI Zhong JI Hehua ZHU Chen GU | 2012 | Frontiers of Structural and Civil Engineering2012，6，2： | 3 |
| 13 | Development and characterization of synthetic amphiploids of Oryza sativa and Oryza latifolia显示文摘Oryza sativa and Oryza latifolia belong to the AA and CCDD genomes of Oryza, respectively. In this study, amphiploids were obtained from the tube seedlings of O. sativa 9 O. latifolia F1 hybrids by treatment with colchicine, an agent for chromosome doubling. Subsequently, amphiploids were investigated using the methods of morphology, genomic in situ hybridization, and molecular markers. Amphiploids were characterized by a shorter plant height, larger diameter of stem, longer and wider leaves, darker leaf color, decreased spikelets per panicle and panicle length, and larger spikelets and anthers than the original F1 hybrid. Based on the mitotic metaphase chromosome number of the investigated root tips, the somatic chromosome number of the amphiploid is 2n = 72.Additionally, the amphiploid is an allohexaploid, and its genomic constitution is AACCDD by genomic in situ hybridization analysis. Finally, the amphiploids were identified to be true using 37 polymorphic markers at the DNA level. | Chuandeng Yi Mingsen Wang Wei Jiang Derong Wang Xiaojun Cheng Ying Wang Yong Zhou Guohua Liang Minghong Gu | 2015 | Science Bulletin2015，60，23： | 3 |
| 14 | Enhancement strategies of targetability, response and photostability for in vivo bioimaging显示文摘Analyses of the physiology and pathology of active biochemical species in their native contexts are critical for early diagnosis and therapy. Optical imaging has emerged as one of the promising modalities for noninvasive and real-time visualization of important biomolecules or biological events, and it has witnessed major advances in the field of imaging in vitro and in vivo. In this review, we present a survey of common approaches and tactics for enhanced targetability, response rate, and photostability in bioimaging applications. Recently developed and representative examples are illustrated on the cellular and tissue levels. | Kaizhi Gu Wei-Hong Zhu Xiaojun Peng | 2019 | Science China Chemistry2019，62，2： | 2 |
| 15 | Experimental demonstration of coherent photonic neural computing based on a Fabry–Perot laser with a saturable absorber显示文摘As Moore’s law has reached its limits,it is becoming increasingly difficult for traditional computing architectures to meet the demands of continued growth in computing power.Photonic neural computing has become a promising approach to overcome the von Neuman bottleneck.However,while photonic neural networks are good at linear computing,it is difficult to achieve nonlinear computing.Here,we propose and experimentally demonstrate a coherent photonic spiking neural network consisting of Mach–Zehnder modulators(MZMs)as the synapse and an integrated quantum-well Fabry–Perot laser with a saturable absorber(FP-SA)as the photonic spiking neuron.Both linear computation and nonlinear computation are realized in the experiment.In such a coherent architecture,two presynaptic signals are modulated and weighted with two intensity modulation MZMs through the same optical carrier.The nonlinear neuron-like dynamics including temporal integration,threshold,and refractory period are successfully demonstrated.Besides,the effects of frequency detuning on the nonlinear neuron-like dynamics are also explored,and the frequency detuning condition is revealed.The proposed hardware architecture plays a foundational role in constructing a large-scale coherent photonic spiking neural network. | DIANZHUANG ZHENG SHUIYING XIANG XINGXING GUO YAHUI ZHANG BILING GU HONGJI WANG ZHENZHEN XU XIAOJUN ZHU YUECHUN SHI YUE HAO | 2023 | Photonics Research2023，11，1： | 2 |
| 16 | Polyps and paralysis phonation classification with nonlinear dynamics model显示文摘In order to provide the basis for parameter selection of vocal diseases classification,a nonlinear dynamic modeling method is proposed.A biomechanical model of vocal cords with polyp or paralysis,which couples to glottal airflow to produce laryngeal sound source,is introduced.And then the fundamental frequency and its perturbation parameters are solved.Poincare section and bifurcation diagram are applied to nonlinear analysis of model vibration.By changing the pathological parameters or subglottal pressure,the changes of fundamental frequency and Lyapunov exponents are analyzed.The simulation results show that,vocal cord paralysis reduces the fundamental frequency,and the chaos occurs only within a certain pressure range;while vocal cord with a polyp don't reduce the fundamental frequency,chaos distributes throughout the entire range of pressure.Therefore this study is helpful for classification of polyp and paralysis by the acoustic diagnoses. | GU Lingling ZHANG Xiaojun HUANG Chengwei WU Di ZHOU Xiaojin TAO Zhi | 2016 | Chinese Journal of Acoustics2016，35，1： | 2 |
| 17 | Assessment of Heavy Metals,Polycyclic Aromatic Hydrocarbons,and Perfluorinated Alkyl Substances in two Marine Crustaceans(Oratosquilla oratoria and Portunus trituberculatus)in the Zhoushan Fishing Ground of China East Sea显示文摘Heavy metals,polycyclic aromatic hydrocarbons(PAHs),and perfluorinated alkyl substances(PFASs)polluted in 155 samples of two marine crustaceans(Oratosquilla oratoria and Portunus trituberculatus)harvested in the Zhoushan fishing ground in the East China Sea were assessed.The results showed that Pb,Hg,and iAs in the whole edible parts of O.oratoria and P.trituberculatus were at trace levels,far below the limits set by the China’s national standard,whereas the exceeding standard rates of Cd in the whole edible parts of O.oratoria and P.trituberculatus were 98.6%and 75.6%,respectively.Moreover,the average Cd levels and the exceeding standard rates of Cd in the visceral tissues of O.oratoria were significantly higher than those in the muscle tissues(4.64 mg kg^(−1)vs.0.49 mg kg^(−1)and 96.7%vs 30%,respectively).PAHs with high detection frequency in the two marine crustaceans included NA,AC,FL,and PHE.Total contents of 15 PAHs(abbreviated asΣ15 PAHs)in whole edible parts of O.oratoria and P.trituberculatus were 10.75–65.9μg kg^(−1)(mean=18.7μg kg^(−1)and 13.26–181μg kg^(−1)(mean=24.2μg kg^(−1),and those in the muscle and the visceral tissues of P.trituberculatus were 9.58–160μg kg^(−1)(mean=21.1μg kg^(−1)and 18.22–201μg kg^(−1)(mean=32.7μg kg^(−1),respectively.Furthermore,PFASs that were found at high contents included PFOA,PFOS,and PFOSA,and total contents of 23 PFASs(Σ23 PFASs)ranged 0.0162–5.104μg kg^(−1)(mean=0.915μg kg^(−1).Collectively,the present work provides new data on the contamination in two marine crustaceans captured in the Zhoushan fishing ground in the China East Sea,which can be useful for making suggestions on proper consumption amounts of the two marine crustaceans. | MEI Guangming ZHANG Xiaojun GU Jie FANG Yi YANG Wenge | 2021 | Journal of Ocean University of China2021，20，6： | 2 |
| 18 | Resi- due behaviour of six pesticides in button crimini dur- ing home canning显示文摘 | DU Pengqiang LIU Xingang GU Xiaojun | 2014 | Food Additives&Contami- nants:Part A2014，31，6： | 1 |
| 19 | Combined processes of two-stage Fenton-biological anaerobic filter–biological aerated filter for advanced treatment of landfill leachate显示文摘 | Xiaojun Wang Jijun Han Zhiwei Chen Lei Jian Xiaoyang Gu Che-Jen Lin | 2012 | Waste Management2012，，12： | 1 |
| 20 | Influence of metal ions onthe structures of Keggin polyoxometalate-based solids:Hydrothermal syntheses,crystal structures and magnet-ic properties显示文摘 | Zhenyu Shi Jun Peng Carlos J Gómez-García SamiaBenmansour Xiaojun Gu | | 0，，179： | 1 |
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