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| 1 | Synthesis and characterization of boron nitride sponges as a novel support for metal nanoparticles显示文摘This paper describes a simple synthetic route for the synthesis of hexagonal boron nitride (h-BN) powders with high specific surface area, in which BBr3, NH4Cl and Al powders are used as starting materials. The structure and composition of the powders were characterized by electron diffraction, Fourier transformation infrared spectroscopy and X-ray photoelectron spectroscopy in the selected area. X-ray diffraction shows wide peaks of crystalline h-BN with the particle size on the nanometer scale, and transmission electron microscopy reveals that the products have a novel spongy morphology. Silver nanoparticles loaded h-BN sponges were prepared via a one-step synthesis method. Different reaction conditions for the formation of h-BN sponges were also investigated. | ZHENG MingTao LIU YingLiang GU YunLe XU ZiLin | 2008 | Science China Chemistry2008，51，3： | 7 |
| 2 | The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients显示文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus. | Jin Liu Lingling Bian Li Ji Yang Chen Heng Chen Yong Gu Bingqin Ma Wei Gu Xinyu Xu Yun Shi Jian Wang Dalong Zhu Zilin Sun Jianhua Ma Hui Jin Xing Shi Heng Miao Bing Xin Yan Zhu Zhenwen Zhang Ruifang Bu Lan Xu Guangde Shi Wei Tang Wei Li Dongmei Zhou Jun Liang Xingbo Cheng Bimin Shi Jixiang Dong Ji Hu Chen Fang Shao Zhong Weinan Yu Weiping Lu Chenguang Wu Li Qian Jiancheng Yu Jialin Gao Xiaoqiang Fei Qingqing Zhang Xueqin Wang Shiwei Cui Jinluo Cheng Ning Xu Guofeng Wang Guoqing Han Chunrong Xu Yun Xie Minmin An Wei Zhang Zhixiao Wang Yun Cai Qi Fu Yu Fu Shuai Zheng Fan Yang Qingfang Hu Hao Dai Yu Jin Zheng Zhang Kuanfeng Xu Yifan Li Jie Shen Hongwen Zhou Wei He Xuqin Zheng Xiao Han Liping Yu Jinxiong She Mei Zhang Tao Yang | 2016 | Science China(Life Sciences)2016，59，9： | 5 |
| 3 | Synthesis and characterization of boron nitride nanoropes 显示文摘 | Zheng Mingtao Gu Yunle Xu Zilin | 2007 | Materials Letters2007，61，： | 1 |
| 4 | Differential Expression of CCNA2 Gene and MMP2 Gene in Skin Tissue of Rex Rabbit with Different Fur Densities显示文摘[Objective] The paper was to search for the molecular marker highly associated with fur density of rex rabbit.[Method] Experimental rex rabbits were divided into dense fur group and sparse fur group.The variation rule of gene expression in skin tissue of rex rabbits with different fur densities was detected using rabbit whole gene c DNA microarray.[Result] A total of 2 657 genes with differential expression were detected by microarray test,including 1 106 genes with known function,687 genes with up-regulated expression and 419 genes with down-regulated expression.The expression levels of multiple genes involving in cell proliferation,differentiation,apoptosis and migration had significant changes.MMP2 gene had high expression in skin tissue of rex rabbits in dense fur group,which was 8.195 times of gene expression in sparse fur group; CCNA2 gene had low expression in skin tissue of rex rabbit in dense fur group,which was0.143 times of gene expression in sparse fur group.[Conclusion] The results provide the theoretical basis and research direction for early breeding of rex rabbit in practical production. | Chen Saijuan Liu Yajuan Chen Baojiang Liu Tao Gu Zilin | 2016 | Animal Husbandry and Feed Science2016，8，5： | 0 |
| 5 | Effects of Distiller's Grain Substrate with Acid Regulation on the Growth of Tobacco Seedlings in Floating Breeding System显示文摘In order to reduce the use of peat resources and realize the sustainable development of tobacco,the pH of distiller's grain substrate was adjusted with humic acid,and the effects of various distiller's grain substrates on the growth of tobacco seedlings were studied to find out the method of cultivating high-quality tobacco seedlings by using distiller's grain substrate. The results showed that when 60% of humic acid was added to the distiller's grain substrate made from coarse distiller's grains,fine distiller's grains,perlite and vermiculite,both the pH and electrical conductivity decreased significantly and were similar to that of the conventional substrate. Moreover,the emergence rate of tobacco seedlings,the rate of strong tobacco seedlings,leaf number,stem height,root growth and quality of tobacco seedlings were good. | Sheng JIANG Sang HU Fei XIONG Yonghui ZHANG Chun XIA Zilin LI Yongyu ZHAO Guangming TANG Fenglan QIN Qixin GU Jinchao ZHAO Junfeng XIN Fuzhao NIAN | 2018 | Agricultural Biotechnology2018，7，4： | 0 |
| 6 | Tunable compact asynchronous optical sampling system using Er-doped fiber laser显示文摘We report a compact,tunable,self-starting,all-fiber laser-based asynchronous optical sampling(ASOPS)system.Two Er-doped fiber oscillators were used as the pulsed-laser source,whose repetition rate could be set at 100 MHz with a tuning range of 1.25 MHz through a fiber delay line.By employing phase-locked and temperature control loops,the repetition rate offset of the two lasers was stabilized with 7.13×10^(−11)fractional instability at an average time of 1 s.Its capabilities in the terahertz regime were demonstrated by terahertz time-domain spectroscopy,achieving a spectral bandwidth of 3 THz with a dynamic range of 30 dB.The large range of repetition rate adjustment in our ASOPS system has the potential to be a powerful tool in the terahertz regime. | Zilin Zhao Daping Luo Yang Liu Zejiang Deng Lian Zhou Gehui Xie Chenglin Gu Yanzhao Yang BinWu Wenxue Li | 2023 | High Power Laser Science and Engineering2023，11，2： | 0 |
| 7 | Inhibition of H_(2)O_(2)-induced apoptosis of GC2-spg cells by functionalized selenium nanoparticles with lentinan through ROSmediated ERK/p53 signaling pathways显示文摘AH_(2)O_(2)-induced oxidative stress injury cell model was established to investigate the antioxidant effect of nanoselenium on mouse spermatocyte lines and the regulation mechanism of the expression level and activity of seleniumcontaining antioxidant enzymes induced by oxidative stress.A safe and effective nano-drug system of functionalized selenium-containing nanoparticles(SeNPs)was developed with lentinan(LNT)(SeNPs@LNT).Mice spermatocyte line GC2-spg cells were treated with SeNPs@LNT(1,2,4,8,16,32μM)for 24-72 h to evaluate the cytotoxicity of selenium.GC2-spg cells were randomly divided into the following groups:control,hydrogen peroxide(H_(2)O_(2)),SeNPs@LNT,and H_(2)O_(2)+SeNPs@LNT groups.H_(2)O_(2)+SeNPs@LNT group was pretreated with SeNPs@LNT 4μM for 12 h,followed by H_(2)O_(2)600μM for 8 h.The cell viability decreased in the H_(2)O_(2) group and increased significantly in the SeNPs@LNT group.Compared with the H_(2)O_(2) group,the SeNPs@LNT+H_(2)O_(2) group exhibited obvious red fluorescence,indicating a higher level of mitochondrial membrane potential.The content of intracellular reactive oxygen species(ROS)in the SeNPs@LNT group reduced significantly,and the intensity of green fluorescence in the SeNPs@LNT+H_(2)O_(2) group decreased significantly compared with the H_(2)O_(2) group,indicating the inhibitory effect of SeNPs@LNT on the generation of ROS-induced oxidative stress.The activity of GPx and SOD increased significantly in the SeNPs@LNT group.The expression of p53 decreased significantly under the intervention of nano-selenium,and GPx1 expression increased.In the oxidative stress group,the expressions of DNA damage-related proteins and apoptosis-related proteins were higher than those in other groups.Thus,SeNPs@LNT can promote GC2-spg cell proliferation,improve GPx and SOD activities,remove intracellular ROS,and reduce mitochondrial damage and functional abnormalities caused by oxidative stress by regulating the ERK and p53 protein levels.SeNPs@LNT has good biological activity and antioxidant effect,which can be used to protect the male reproductive system from oxidative stress. | MIAOMIAO LI DANYANG CHEN JUNYI KE RUILIN ZHENG JINGYAO SU ZILIN ZHENG JIEYI LUO HANRAN MAI FAN JIANG YANXIA QU XIAOQIONG GU BING ZHU YINGHUA LI LIANDONG ZUO | 2023 | BIOCELL2023，47，2： | 0 |
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