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| 1 | Clinical efficacy and safety of moxifloxacin versus levofloxacin plus metronidazole for community-acquired pneumonia with aspiration factors显示文摘 | Sun Tieying Sun Li Wang Rongmei Ren Xiaoping Sui Dong-jiang Pu Chun Ren Yajuan Liu Ying Yang Zhuo Li Fengzhi | 2014 | Chinese Medical Journal2014，，7： | 34 |
| 2 | Tectonic Evolution of the Meso-Tethys in the Western Segment of Bangonghu-Nujiang Suture Zone: Insights from Geochemistry and Geochronology of the Lagkor Tso Ophiolite显示文摘The subduction of the Bangonghu-Nujiang Meso-Tethys and the collision between the Lhasa and Qiangtang blocks were important events in the growth of the Tibetan crust. However,the timing of collision initiation and closure timing,as well as nature and structure of the Bangonghu ocean basin,are still poorly constrained. The Lagkor Tso ophiolite,located in the south of Gerze County,Tibet,is one of the most completed ophiolites preserved in the southern side of the BangonghuNujiang suture zone. This study discussed the tectonic evolution of the Bangonghu-Nujiang suture zone as revealed by the Lagkor Tso ophiolite investigated by field investigations,petrology,geochemistry,geochronology and tectonic analysis methods. We present new LA-ICP-MS zircon U-Pb and 39Ar/40 Ar ages for the Lagkor Tso ophiolite,in addition to geochemical and platinum-group element(PGE) data presented for the Lagkor Tso ophiolite in Tibet. It is suggested that the ancient Lagkor Tso oceanic basin split in Middle Jurassic(161.2 ± 2.7 Ma – 165.4 ± 3.5 Ma),and experienced a second tectonic emplacement during the Early Cretaceous(137.90 ± 6.39 Ma). The Lagkor Tso ophiolite likely developed in an independent suture zone. The Bangonghu-Nujiang ocean subducted southwards,and the dehydration of the subducting oceanic crust materials caused partial melting of the continental mantle wedge,which formed the second-order expanding center of the obduction dish. This led to inter-arc expansion,followed by the formation of inter-arc and back-arc basins with island arc features,which are represented by ophiolites around the Shiquanhe-Lagkor Tso-Yongzhu region. The tectonic environment presently can be considered to be similar to that of the current Western Pacific,in which a large number of island arc-ocean basin systems are developed. | YUAN Yajuan YIN Zhengxin LIU Weiliang HUANG Qiangtai LI Jianfeng LIU Hongfei WAN Zhifeng CAI Zhourong XIA Bin | 2015 | Acta Geologica Sinica(English Edition)2015，89，2： | 17 |
| 3 | Effects of Land Use Change on Ecosystem Services in Arid Area Ecological Migration显示文摘Ecological migration is the process of increasing the population density in the immigration area and transferring the ecological pressure from emigration area to immigration area. This process may result in significant changes in land use and land cover in the area of immigration and have an important effect on ecosystem services. Therefore, scientifically revealing the effects and differentiation mechanisms of ecological migration on ecosystem services is becoming an important issue related to the implementation of the national ecological migration strategy in China. This study employed the Hongsibu District as a typical example of ecological migration. Hongsibu District is located in the central Ningxia steppe and desert steppe areas. Remote sensing data covering five periods from the period before ecological migration in 1995 and after migration in 2000, 2005, 2010, and 2015 was used to measure the value of ecosystem services(ESV). A geographical detector model and the value of ecosystem services model were used to diagnose the dynamic mechanism of the effects of land use change on ecosystem services. The results showed that: 1) The development of large-scale ecological resettlement has caused the area of cultivated land and urbanized land area to increase significantly in the area of immigration, while the grass area decreased significantly. 2) The overall value of the Hongsibu ecosystem services increased in a form of a ‘V'. Among them, during the period of 1995–2005, the overall ESV decreased and had an annual rate of change of-0.67%. During the period of development 2005–2015, the ESV increased steadily, with an annual rate of change of 0.79%. 3) The proportion and total ESV in soil formation and protection, waste treatment, and biodiversity conservation of the Hongsibu District decreased from 57.61% in 1995 to 56.17% in 2015, indicating that the region's ecological regulation function slightly decreased. 4) The ESV in the Hongsibu District, showed a low distribution pattern of ecosystem services increasing from northeast to southwest, and the capacity of three townships, Hongsibu, Taiyangshan, and Liuquan, to provide ecosystem services gradually declined over time. The ecological service function of Xinzhuangji Township and Dahe Township gradually improved. 5) The sensitivity index of the ESV of each land use type was less than 1, indicating that the environment lacks flexibility in providing a strong ESV index in Hongsibu, which shows that the research results are reliable and believable. 6) During the study period, the decisive force of the change of land use on ecosystem services in Hongsibu District was: grassland(0.9934), climate regulation(0.9413), soil formation and protection(0.9321) and waste treatment(0.9241). | LIU Xiaopeng CHEN Xiao HUA Kaiping WANG Yajuan WANG Peng HAN Xiaojia YE Junyan WEN Shengqiang | 2018 | Chinese Geographical Science2018，28，5： | 9 |
| 4 | Combined effects of cadmium and fluoranthene on germination, growth and photosynthesis of soybean seedlings显示文摘The single and combinational effects of cadmium (Cd) and fluoranthene (FLT) on germination, growth and photosynthesis of soybean seedlings were investigated. Exposure to 5, 10, or 15 mg Cd/L or 1, 5, or 10 mg FLT/L individually or in combination significantly decreased germination vigor (3 days) and final germination rate of soybean seeds, except at 1 and 5 mg FLT/L. The results of two-way ANOVA analysis and the Bliss independence model showed that at lower concentrations of FLT (1 mg/L), the interaction between Cd and FLT on germination was antagonistic, whereas the interaction was synergistic when the concentration of FLT was 5 or 10 mg/L and the concentration of Cd was 15 mg/L. Growth, expressed as dry weight, length of shoot and root, leaf area, and photosynthesis, expressed as net photosynthetic rate, intercellular CO2 concentration, chlorophyll contents and fluorescence of soybean seedlings were also reduced by exposure to 5 or 10 mg Cd/L or 1 or 5 mg FLT/L, singly or jointly. Significant antagonistic effects of exposure to 5 or 10 mg Cd/L or 1 or 5 mg FLT/L on shoot growth and photosynthesis were observed, whereas synergy and antagonism of Cd and FLT were both observed for root growth. | Qiushuang Li Yonglong Lu Yajuan Shi Tieyu Wang Kun Ni Li Xu Shijie Liu Lin Wang Qinli Xiong John.P Giesy | 2013 | Journal of Environmental Sciences2013，25，9： | 8 |
| 5 | Clinical features and the traditional Chinese medicine therapeutic characteristics of 293 COVID-19 inpatient cases显示文摘Coronavirus disease 2019 (COVID-19) is now pandemic worldwide and has heavily overloaded hospitals in Wuhan City, China during the time between late January and February. We reported the clinical features and therapeutic characteristics of moderate COVID-19 cases in Wuhan that were treated via the integration of traditional Chinese medicine (TCM) and Western medicine. We collected electronic medical record (EMR) data, which included the full clinical profiles of patients, from a designated TCM hospital in Wuhan. The structured data of symptoms and drugs from admission notes were obtained through an information extraction process. Other key clinical entities were also confirmed and normalized to obtain information on the diagnosis, clinical treatments, laboratory tests, and outcomes of the patients. A total of 293 COVID-19 inpatient cases, including 207 moderate and 86 (29.3%) severe cases, were included in our research. Among these cases, 238 were discharged, 31 were transferred, and 24 (all severe cases) died in the hospital. Our COVID-19 cases involved elderly patients with advanced ages (57 years on average) and high comorbidity rates (61%). Our results reconfirmed several well-recognized risk factors, such as age, gender (male), and comorbidities, as well as provided novel laboratory indications (e.g., cholesterol) and TCM-specific phenotype markers (e.g., dull tongue) that were relevant to COVID-19 infections and prognosis. In addition to antiviral/antibiotics and standard supportive therapies, TCM herbal prescriptions incorporating 290 distinct herbs were used in 273 (93%) cases. The cases that received TCM treatment had lower death rates than those that did not receive TCM treatment (17/273= 6.2% vs. 7/20= 35%, P = 0.0004 for all cases;17/77= 22% vs. 7/9= 77.7%, P = 0.002 for severe cases). The TCM herbal prescriptions used for the treatment of COVID-19 infections mainly consisted of Pericarpium Citri Reticulatae, Radix Scutellariae, Rhizoma Pinellia, and their combinations, which reflected the practical TCM principles (e.g., clearing heat and dampening phlegm). Lastly, 59% of the patients received treatment, including antiviral, antibiotics, and Chinese patent medicine, before admission. This situation might have some effects on symptoms, such as fever and dry cough. By using EMR data, we described the clinical features and therapeutic characteristics of 293 COVID-19 cases treated via the integration of TCM herbal prescriptions and Western medicine. Clinical manifestations and treatments before admission and in the hospital were investigated. Our results preliminarily showed the potential effectiveness of TCM herbal prescriptions and their regularities in COVID-19 treatment. | Zixin Shu Yana Zhou Kai Chang Jifen Liu Xiaojun Min Qing Zhang Jing Sun Yajuan Xiong Qunsheng Zou Qiguang Zheng Jinghui Ji Josiah Poon Baoyan Liu Xuezhong Zhou Xiaodong Li | 2020 | Frontiers of Medicine2020，14，6： | 7 |
| 6 | A pH-responsive TiO_2-based Pickering emulsion system for in situ catalyst recycling显示文摘Developing methods for efficient product/catalyst separation and catalyst recycling is meaningful in multi-phase catalytic reactions. Here, we reported a p H-responsive emulsion system stabilized by interfacially active TiO_2 nanoparticles for achieving in situ product/catalyst separation and catalyst recycling. In this system, emulsification and demulsification process could be easily engineered through tuning the p H values. The emulsion droplets were destroyed completely at a p H value of 3–4, and the solid catalyst distributed in the aqueous phase could be used to the next reaction cycle after removal of the organic product and adjusting the p H to 7–8. Such a p H triggered switchable Pickering emulsion catalytic system not only shows good recyclability of the solid catalyst but also high catalytic efficiency,and could be recycled more than 10 cycles. | Yajuan Hao Yanfang Liu Rui Yang Xiaoming Zhang Jian Liu Hengquan Yang | 2018 | Chinese Chemical Letters2018，29，6： | 5 |
| 7 | Maghemite(γ-Fe_2O_3) nanoparticles enhance dissimilatory ferrihydrite reduction by Geobacter sulfurreducens: Impacts on iron mineralogical change and bacterial interactions显示文摘Microbially mediated bioreduction of iron oxyhydroxide plays an important role in the biogeochemical cycle of iron.Geobacter sulfurreducens is a representative dissimilatory ironreducing bacterium that assembles electrically conductive pili and cytochromes.The impact of supplementation withγ-Fe_2O_3 nanoparticles(NPs)(0.2 and 0.6 g)on the G.sulfurreducens-mediated reduction of ferrihydrite was investigated.In the overall performance of microbial ferrihydrite reduction mediated byγ-Fe_2O_3 NPs,stronger reduction was observed in the presence of direct contact withγ-Fe_2O_3 NPs than with indirect contact.Compared to the production of Fe(Ⅱ)derived from biotic modification with ferrihydrite alone,increases greater than 1.6-and 1.4-fold in the production of Fe(Ⅱ)were detected in the biotic modifications in which direct contact with 0.2 g and 0.6 gγ-Fe_2O_3 NPs,respectively,occurred.X-ray diffraction analysis indicated that magnetite was a unique representative iron mineral in ferrihydrite when active G.sulfurreducens cells were in direct contact withγ-Fe_2O_3 NPs.Because of the sorption of biogenic Fe(Ⅱ)ontoγ-Fe_2O_3 NPs instead of ferrihydrite,the addition ofγ-Fe_2O_3 NPs could also contribute to increased duration of ferrihydrite reduction by preventing ferrihydrite surface passivation.Additionally,electron microscopy analysis confirmed that the direct addition ofγ-Fe_2O_3 NPs stimulated the electrically conductive pili and cytochromes to stretch,facilitating long-range electron transfer between the cells and ferrihydrite.The obtained findings provide a more comprehensive understanding of the effects of iron oxide NPs on soil biogeochemistry. | Zheng Chen Yaxian Zhang Qingliu Luo Liuying Wang Shurui Liu Yajuan Peng Haitao Wang Liang Shen Qingbiao Li Yuanpeng Wang | 2019 | Journal of Environmental Sciences2019，31，4： | 5 |
| 8 | Biodegradable metals for bone defect repair:A systematic review and meta-analysis based on animal studies显示文摘Biodegradable metals are promising candidates for bone defect repair.With an evidence-based approach,this study investigated and analyzed the performance and degradation properties of biodegradable metals in animal models for bone defect repair to explore their potential clinical translation.Animal studies on bone defect repair with biodegradable metals in comparison with other traditional biomaterials were reviewed.Data was carefully collected after identification of population,intervention,comparison,outcome,and study design(PICOS),and following the inclusion criteria of biodegradable metals in animal studies.30 publications on pure Mg,Mg alloys,pure Zn and Zn alloys were finally included after extraction from a collected database of 2543 publications.A qualitative systematic review and a quantitative meta-analysis were performed.Given the heterogeneity in animal model,anatomical site and critical size defect(CSD),biodegradable metals exhibited mixed effects on bone defect repair and degradation in animal studies in comparison with traditional non-degradable metals,biodegradable polymers,bioceramics,and autogenous bone grafts.The results indicated that there were limitations in the experimental design of the included studies,and quality of the evidence presented by the studies was very low.To enhance clinical translation of biodegradable metals,evidence-based research with data validity is needed.Future studies should adopt standardized experimental protocols in investigating the effects of biodegradable metals on bone defect repair with animal models. | Jiazhen Zhang Yanbiao Jiang Zhizhong Shang Bing Zhao Mingyue Jiao Wenbo Liu Maobo Cheng Bao Zhai Yajuan Guo Bin Liu Xinli Shi Bin Ma | 2021 | Bioactive Materials2021，6，11： | 5 |
| 9 | Geochemistry,Geochronology,Sr-Nd Isotopic Compositions of Jiang Tso Ophiolite in the Middle Segment of the Bangong- Nujiang Suture Zone and Their Geological Significance显示文摘The Jiang Tso ophiolite,situated in the middle segment of the Bangong- Nujiang Suture Zone,is a part of the easternmost Qieli Lake ophiolite subzone and is close to the south of Pung Lake ophiolite. The rock association of Jiang Tso ophiolite is relatively complete and is mainly composed of metamorphic peridotite,gabbro and diabase. Comparing with N-MORB,the ophiolite is high in Mg and low in Ti,K,Na,P,and is depleted in Nb,Ta,Hf,Th and enriched in Rb,Sr and Ba. Geochemical characteristics of the Jiang Tso ophiolite indicate it is of a supra-subduction zone type formed in the spreading ridge of back arc basin. The SHRIMP U-Pb dating of zircons from the gabbro yielded a weighted average age of 188.1±4.1 Ma(MSWD=1.4),indicating the Jiang Tso ophiolite was formed in the late stage of early Jurassic. The Sr,Nd isotopic compositions show that the Tethyan mantle domain is the depleted mantle(DM),with enriched mantle domain II(EM II). They have the same Sr,Nd isotopic composition with the India Ocean MORB type. | HUANG Qiangtai LI Jianfeng CAI Zhourong XIA Lianze YUAN Yajuan LIU Huichuan XIA Bin | 2015 | Acta Geologica Sinica(English Edition)2015，89，2： | 4 |
| 10 | Post-marketing safety surveillance and reevaluation of Motherwort injection:A clinical study of 10094 cases显示文摘OBJECTIVE:To investigate the safety profiles of Motherwort injection(MI).METHODS:A multi-center,prospective and drugderived hospital intensive monitoring method was conducted to assess the safety of MI in real world applications.This study was based on a very large population after the injection was approved and marketed in China.All patients using the injection in participating hospitals were monitored to determine the incidence,pattern,severity and outcome of associated adverse events.RESULTS:The post-marketing surveillance was performed in 10 094 female patients from April to December,2015.The incidence of adverse drug reactions(ADRs) was 0.79‰(8/10 094).Among the 8 patients,the reported adverse events mainly included systemic abnormalities,such as fever,chills and eyelid edema;skin and appendages disorders,such as pruritus and rash;gastrointestinal disorders,such as nausea,abdominal distension and pain;heart rate and rhythm disorders,such as palpitation and increased heart rate.All of these ADRs were mild in severity.CONCLUSION:In this study the ADRs incidence rate of MI is very low,which supports that it is generally safe for use in obstetric and gynecological diseases.However,the total number of 8 ADRs recorded over a relatively short time span seems limited,and the low number of reports could not represent an absolute guarantee of safety. | Cao Shan Zhang Wenhao Zhao Ziwei Heng Mingli Bu Huaien Wang Hongwu Liu Xinghui Wang Zhong Cai Yan Ma Yuyan Cui Shihong Deng Jihong Ding Guifeng Ding Yajuan Dong Linhong Duan Zhentao Fan Ling Fan Yang Fu Fen He Jing Ji Shuying Jin Lin Li Hong Li Hongying Liao Tao Lu Wei Luo Xiucui Lü Zhihui Ma Fengchun Ma Dafeng Shi Tianyun Sun Juying Sun Xiaotong Teng Hong Wang Jinhua Wang Ruihua Wang Ying Wang Zhengling Xi Jie Xu Minjuan Xu Zhihong Yan Qian Yang Cuirong Yang Yimei Yin Jie Yu Jinhua Yuan Wenjun Zhang Guanli Zhang Meihua Zhao Renfeng Zhong Yonghong Zhou Jian | 2018 | Journal of Traditional Chinese Medicine2018，38，4： | 4 |
| 11 | A biomass carbon material with microtubule bundling and natural O-doping derived from goldenberry calyx and its electrochemical performance in supercapacitor显示文摘A promising biomass carbon material,manufactured by the carbonation of Physalis peruviana L.calyx at 700℃,is presented in this wo rk.Morphology characterization shows that the carbon material possesses long microtubule bundling and above 30%natural O-atom component on the surface.After KOH chemical etching,the materials maintain the oxygen content but exhibit more micropores and higher specific surface area up to 1732.6 m^2/g.Using as an electrode material for supercapacitor,the active carbon material exhibits high specific capacitance up to 339.7 F/g at 0.5 A/g in 3 mol/L KOH aqueous solution through three-electrode system.The active carbon material also exhibits excellent cycling stability(97%retention)by 10,000 cycles at 10 A/g.The outstanding electrochemical performances are attributing to the unique long microtubule bundling with much more pores and the abundant Oelement on the surface.This biomass carbon material with excellent electrochemical properties could be a useful material for multiple applications. | Yang Liu Mengyi Zhang Liqiu Wang Yajuan Hou Chenxiao Guo Haiying Xin Shuang Xu | 2020 | Chinese Chemical Letters2020，31，3： | 4 |
| 12 | A Research on Bilingual Dictionary Based Sentence Alignment for Chinese English Parallel Corpus显示文摘Parallel corpus is of great importance to machine translation, and automatic sentence alignment is the first step towards its processing. This paper puts forward a bilingual dictionary based sentence alignment method for Chinese English parallel corpus, which differs from previous length based algorithm in its knowledge-rich approach. Experimental result shows that this method produces over 93% accuracy with usual English-Chinese dictionaries whose translations cover 31 88%~47 90% of the corpus. | 杨沐昀 Li Sheng Zhao Tiejun Lu Yajuan Liu Zhanyi | 2002 | High Technology Letters2002，8，1： | 3 |
| 13 | Female Reproductive Cycles of Phrynocephalus przewalskii (Lacertilia:Agamidae) in the Tengger Desert,China显示文摘The timing of reproduction can significantly affect an offspring's fitness, thereby also influencing the fitness of the parents, especially in species inhabiting extreme environments, such as deserts. Female reproductive cycles in Phrynocephalus przewalskii were studied from April to September 2008. Significant cycles of gonadal volume were found in all studied populations and the cycles were similar among the various populations. Females began vitellogenesis in April and contained oviductal eggs form May to June. Gonad volume decreased significantly in July and reached minimum volume from August to September. The follicular growth was negatively correlated with increasing precipitation and temperature in all populations. Hatching occurs during summer and early fall, when most of the annual rainfall occurs. Mean clutch size based on all populations was 2.7 ± 0.9 SE(n = 71). | Wei ZHAO Nannan YU Yajuan WANG Weihong JI Naifa LIU | 2011 | Asian Herpetological Research2011，2，1： | 3 |
| 14 | Geographic Variation in Clutch and Egg Size for the Lizard Phrynocephalus przewalskii(Squamata:Agamidae)显示文摘In order to tease apart proximate vs.ultimate sources of variation in reproductive strategy,studies have increasingly focused on populations rather than species as the unit of interest.The reproductive parameters of Phrynocephalus przewalskii(Agamidae)in different populations within the same phylogenetic clade were compared in this study.Female SVL,clutch size,egg volume and clutch volume varied significantly among populations.With increase in latitude,clutch size increased,while egg size decreased.Relatively fewer but larger eggs were produced with increasing of population density.Food availability had positive effects on clutch size,but no effect on egg size.Our result indicated that latitude,food availability and population density may be the proximate factors affecting the reproductive parameters of P.przewalskii. | Yajuan WANG Weihong JI Wei ZHAO Nannan YU Naifa LIU | 2011 | Asian Herpetological Research2011，2，2： | 2 |
| 15 | miR-7/TGF-β2 axis sustains acidic tumor microenvironment-induced lung cancer metastasis显示文摘Acidosis,regardless of hypoxia involvement,is recognized as a chronic and harsh tumor microenvironment(TME)that educates malignant cells to thrive and metastasize.Although overwhelming evidence supports an acidic environment as a driver or ubiquitous hallmark of cancer progression,the unrevealed core mechanisms underlying the direct effect of acidification on tumorigenesis have hindered the discovery of novel therapeutic targets and clinical therapy.Here,chemical-induced and transgenic mouse models for colon,liver and lung cancer were established,respectively.miR-7 and TGF-β2 expressions were examined in clinical tissues(n=184).RNA-seq,miRNA-seq,proteomics,biosynthesis analyses and functional studies were performed to validate the mechanisms involved in the acidic TME-induced lung cancer metastasis.Our data show that lung cancer is sensitive to the increased acidification of TME,and acidic TME-induced lung cancer metastasis via inhibition of miR-7-5 p.TGF-β2 is a direct target of miR-7-5 p.The reduced expression of miR-7-5 p subsequently increases the expression of TGF-β2 which enhances the metastatic potential of the lung cancer.Indeed,overexpression of miR-7-5 p reduces the acidic p H-enhanced lung cancer metastasis.Furthermore,the human lung tumor samples also show a reduced miR-7-5 p expression but an elevated level of activated TGF-β2;the expressions of both miR-7-5 p and TGF-β2 are correlated with patients’survival.We are the first to identify the role of the miR-7/TGF-β2 axis in acidic p H-enhanced lung cancer metastasis.Our study not only delineates how acidification directly affects tumorigenesis,but also suggests miR-7 is a novel reliable biomarker for acidic TME and a novel therapeutic target for non-small cell lung cancer(NSCLC)treatment.Our study opens an avenue to explore the p H-sensitive subcellular components as novel therapeutic targets for cancer treatment. | Tao Su Suchao Huang Yanmin Zhang Yajuan Guo Shuwei Zhang Jiaji Guan Mingjing Meng Linxin Liu Caiyan Wang Dihua Yu Hiu-Yee Kwan Zhiying Huang Qiuju Huang Elaine Lai-Han Leung Ming Hu Ying Wang Zhongqiu Liu Linlin Lu | 2022 | Acta Pharmaceutica Sinica B2022，12，2： | 2 |
| 16 | Chemical functionalization of 2D black phosphorus显示文摘As an emerging two-dimensional material,black phosphorus(BP)has fascinating structure and electronic properties,affording broad applications in fieldeffect transistors,optoelectronic devices,energy devices,and biomedicines.However,the lone pair electrons of phosphorus atoms readily react with oxygen,so few-layer BP is easily oxidized and degraded when exposed to air.Therefore,the ambient stability of BP needs to be enhanced for its potential application.Chemical functionalization is one of the most effective methods for improving the ambient stability of few-layer BP.In this review,we provide a comprehensive overview of the chemical functionalization of BP,focusing on covalent and noncovalent functionalization and surface coordination.The influence of the functionalization pattern on the electronic properties and ambient stability of BP is summarized.Finally,the challenges and future development of chemical functionalization of BP are discussed. | Yajuan Liu Muqing Chen Shangfeng Yang | 2021 | InfoMat2021，3，3： | 2 |
| 17 | Water environmental planning and management at the watershed scale:A case study of Lake Qilu,China显示文摘Water environmental planning and management has become essential for guiding the water pollution control activities.Past water pollution control activities have been site specific,with little thought on water quality standard reaching at the watershed scale.Based on the watershed approach,a seven-step methodological framework for water environmental planning and management was developed.The framework was applied to water environmental planning and management of the Lake Qilu watershed in Yunnan Province,China.Results show that the reduction amount of total nitrogen(TN)under the plan is 1,205 tons per year so that the target of environmental capacity can be reached in 2020.Compared with traditional methods,the framework has its prevalence and could be generalized to analogous watersheds. | Kai HUANG Huaicheng GUO Yong LIU Feng ZHOU Yajuan YU Zhen WANG | 2008 | Frontiers of Environmental Science & Engineering2008，2，2： | 2 |
| 18 | Early changes to the extracellular space in the hippocampus under simulated microgravity conditions显示文摘The smooth transportation of substances through the brain extracellular space(ECS)is crucial to maintaining brain function;however,the way this occurs under simulated microgravity remains unclear.In this study,tracer-based magnetic resonance imaging(MRI)and DECS-mapping techniques were used to image the drainage of brain interstitial fluid(ISF)from the ECS of the hippocampus in a tail-suspended hindlimb-unloading rat model at day 3(HU-3)and 7(HU-7).The results indicated that drainage of the ISF was accelerated in the HU-3 group but slowed markedly in the HU-7 group.The tortuosity of the ECS decreased in the HU-3 group but increased in the HU-7 group,while the volume fraction of the ECS increased in both groups.The diffusion rate within the ECS increased in the HU-3 group and decreased in the HU-7 group.The alterations to ISF drainage and diffusion in the ECS were recoverable in the HU-3 group,but neither parameter was restored in the HU-7 group.Our findings suggest that early changes to the hippocampal ECS and ISF drainage under simulated microgravity can be detected by tracer-based MRI,providing a new perspective for studying microgravity-induced nano-scale structure abnormities and developing neuroprotective approaches involving the brain ECS. | Yajuan Gao Hongbin Han Jichen Du Qingyuan He Yanxing Jia Junhao Yan Hui Dai Bin Cui Jing Yang Xunbin Wei Liu Yang Rui Wang Ren Long Qiushi Ren Xing Yang Jiabin Lu | 2022 | Science China(Life Sciences)2022，65，3： | 2 |
| 19 | Effects of shade treatments on the photosynthetic capacity, chlorophyll fluorescence, and chlorophyll content of Tetrastigma hemsleyanum Diels et Gilg显示文摘 | Yajuan Dai Zonggen Shen Ying Liu Lanlan Wang David Hannaway Hongfei Lu | 2008 | Environmental and Experimental Botany2008，，2： | 1 |
| 20 | In vitro inhibition of CSFV replication by multiple siRNA expression显示文摘 | Jiangnan Li Yajuan Dai Shuai Liu Huancheng Guo Tiedong Wang Hongsheng Ouyang Changchun Tu | 2011 | Antiviral Research2011，，2： | 1 |
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