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| 1 | A New Nodes-Based Model for Optimization of Heat Exchanger Network Synthesis显示文摘Searching the global optimal value in heat exchanger network synthesis (HENS) becomes more difficult along with the increasing scale of cases.In structural opitimization model,such as stage-wise superstructure,solution domain can be enlarged by adding the stages of network,which would involve multiple integer and continuous variables in optimization and result in a decreasing computational efficiency.Thus,a new nodes-based model with stream splits is proposed,which can promote the quality of result and decrease time consumption at the same time.The characteristic of this model is that it changes the matching mode of heat exchangers by setting the number of nodes on streams to quantify the positions of heat exchangers.The proposed nodes-based model has more flexibility in generating and eliminating the heat exchangers and strong ductility in exploring the solution domain.The random walk with compulsive evolution is modified for enhancing its searching ability and applying modified random walk algorithm with compulsive evolution (RWCE) into the new proposed model.The obtained results of Case 1,Case 2 and Case 3 are superior to those reported in the literature,which decreases 106 USD·a-1,1253 USD·a-1,23 444 USD·a-1,respectively,verifying the robust effectiveness of this new model in solving HENS problem. | XU Yue HERI Ambonisye Kayange XIAO Yuan CUI Guomin | 2021 | Journal of Thermal Science2021，30，2： | 4 |
| 2 | Galectin-3-centered paracrine network mediates cardiac inflammation and fibrosis upon β-adrenergic insult显示文摘Rapid over-activation of β-adrenergic receptors (β-AR) following acute stress initiates cardiac inflammation and injury by activating interleukin-18 (IL-18),however,the process of inflammation cascades has not been fully illustrated.The present study aimed to determine the mechanisms of cardiac inflammatory amplification following acute sympathetic activation.With bioinformatics analysis,galectin-3 was identified as a potential key downstream effector of β-AR and IL-18 activation.The serum level of galectin-3 was positively correlated with norepinephrine or IL-18 in patients with chest pain.In the heart of mice treated with β-AR agonist isoproterenol (ISO,5 mg kg^(-1)),galectin-3 expression was upregulated markedly later than IL-18 activation,and Nlrp3^(-/-)and Il18^(-/-)mice did not show ISO-induced galectin-3 upregulation.It was further revealed that cardiomyocyte-derived IL-18 induced galectin-3 expression in macrophages following ISO treatment.Moreover,galectin-3deficiency suppressed ISO-induced cardiac inflammation and fibrosis without blocking ISO-induced IL-18 increase.Treatment with a galectin-3 inhibitor,but not a β-blocker,one day after ISO treatment effectively attenuated cardiac inflammation and injury.In conclusion,galectin-3 is upregulated to exaggerate cardiac inflammation and injury following acute β-AR activation,a galectin-3 inhibitor effectively blocks cardiac injury one day after β-AR insult. | Guomin Hu Jimin Wu Huijun Gu Xiangning Deng Wenli Xu Shan Feng Shuaixing Wang Yao Song Zhengda Pang Xiuling Deng Aleksandr E.Vendrov Nageswara R.Madamanchi Marschall S.Runge Xinyu Wang Youyi Zhang Han Xiao Erdan Dong | 2023 | Science China(Life Sciences)2023，66，5： | 3 |
| 3 | Pathological matrix stiffness promotes cardiac fibroblast differentiation through the POU2F1 signaling pathway显示文摘Cardiac fibroblast(CF)differentiation into myofibroblasts is a crucial cause of cardiac fibrosis,which increases in the extracellular matrix(ECM)stiffness.The increased stiffness further promotes CF differentiation and fibrosis.However,the molecular mechanism is still unclear.We used bioinformatics analysis to find new candidates that regulate the genes involved in stiffnessinduced CF differentiation,and found that there were binding sites for the POU-domain transcription factor,POU2F1(also known as Oct-1),in the promoters of 50 differentially expressed genes(DEGs)in CFs on the stiffer substrate.Immunofluorescent staining and Western blotting revealed that pathological stiffness upregulated POU2F1 expression and increased CF differentiation on polyacrylamide hydrogel substrates and in mouse myocardial infarction tissue.A chromatin immunoprecipitation assay showed that POU2F1 bound to the promoters of fibrosis repressors IL1R2,CD69,and TGIF2.The expression of these fibrosis repressors was inhibited on pathological substrate stiffness.Knockdown of POU2F1 upregulated these repressors and attenuated CF differentiation on pathological substrate stiffness(35 kPa).Whereas,overexpression of POU2F1 downregulated these repressors and enhanced CF differentiation.In conclusion,pathological stiffness upregulates the transcription factor POU2F1 to promote CF differentiation by inhibiting fibrosis repressors.Our work elucidated the crosstalk between CF differentiation and the ECM and provided a potential target for cardiac fibrosis treatment. | Mingzhe Li Jimin Wu Guomin Hu Yao Song Jing Shen Junzhou Xin Zijian Li Wei Liu Erdan Dong Ming Xu Youyi Zhang Han Xiao | 2021 | Science China(Life Sciences)2021，64，2： | 3 |
| 4 | OVERVIEW OF SEVERE TYPHOON FITOW AND ITS OPERATIONAL FORECASTS显示文摘Severe typhoon Fitow(1323)brought persistent and heavy rainfall to Zhejiang and the Shanghai area after it made landfall at Fujian Province of China in October 2013,breaking the rainfall records of several counties and districts in Zhejiang.In this paper,we provide an overview of the characteristics of Fitow’s landfall,including its track,intensity,structural evolution,heavy rainfall,and wind.We also describe some of the associated disastrous impacts.Finally,we provide verifications of operational forecasts of its track,intensity and rainfall.Though the track and intensity is well predicted,the rainfall persistence and enhancement in the second stage in Shanghai and north Zhejiang areas are not predicted out at all.The analysis presented in this paper provides forecasters and researchers with some valuable information on Fitow,which could form a useful basis for further studies. | ZIFENG YU YANDIE CHEN DAN WU GUOMIN CHEN XUWEI BAO QIUZHEN YANG RUNLING YU LEI ZHANG JIE TANG MING XU ZHIHUA ZENG | 2014 | Tropical Cyclone Research and Review2014，3，1： | 2 |
| 5 | Artful Application of Garden Plants in Classical Suzhou Gardens显示文摘Defi nition of plant landscaping and features of plant landscaping in classical Suzhou gardens were introduced, the forms of combining plants and buildings, rockeries and waterscapes were analyzed by elaborating selection of plant species and plant furnishings. In addition, manifestation of artistic beauty of the classical Suzhou gardens was explored, and protective measures were given. | XU Xifeng HE Guomin | 2014 | Journal of Landscape Research2014，6，1： | 2 |
| 6 | A New Revocable and Re-Delegable Proxy Signature and Its Application显示文摘与云计算和活动应用软件的流行,象联机音乐或听觉的流并且车辆订那样的按需的服务现在是广泛地可得到的。以便允许服务的有效交货和管理为大规模按需的系统,通常有一个层次,服务供应商能托付它的服务到在哪儿一最高级(例如,全国) 代理然后能进一步托付服务到底层(例如,区域宽) 代理。安全(re-) 代表团和撤回在为如此的系统的最关键的因素之中。在这份报纸,我们为完成重新代表团和撤回利用代理签名调查实际答案。尽管代理签名广泛地在文学被学习了,没有以前的答案能完成两个性质。充满差距,我们介绍支持有效撤回并且允许一位代理签名人到的可撤回、 re 可以委托的代理签名的观点重新托付它没有和原来的签名人的相互作用的另外的代理签名人的签名权利。我们为这新原语定义正式安全模型并且介绍能完成所有安全性质的一个有效计划。我们也介绍一安全联机可撤回并且重新托付作为我们的建议计划的应用程序之一订系统(RRVOS ) 的车辆。 | Shengmin Xu Guomin Yang Yi Mu | 2018 | Journal of Computer Science & Technology2018，33，2： | 2 |
| 7 | Transesterifica- tion of Palm Oil with Methanol to Biodiesel over a KF/AI2Oa Heterogeneous Base Catalyst显示文摘 | Xu Bo Xiao Guomin Cui Lingfeng | 2007 | Energy Fuels2007，21，6： | 1 |
| 8 | An areal recharge and discharge simulating method for MODFLOW 显示文摘 | Dong Yanhui Li Guomin Xu Haizhen | 2012 | Computers & Geosciences2012，42，： | 1 |
| 9 | Evaluation of a new fungus Ceriporia lacerate strain P2—its ability to decolorize Alizarin Red and Methyl Orange显示文摘 | Liang Xu Yue Zhu Xingbing He Guomin Han Xingjun Tian | | 0，2008，： | 1 |
| 10 | Impaired hippocampal neurogenesis is involved in cognitive dysfunction induced by thiamine deficiency at early pre-pathological lesion stage显示文摘 | Na Zhao Chunjiu Zhong Yang Wang Yanling Zhao Neng Gong Guomin Zhou Tianle Xu Zhen Hong | 2007 | Neurobiology of Disease2007，，2： | 1 |
| 11 | Transesterification of palmoil with methanol to biodiesel over a KF/hydrotalcite solid catalyst显示文摘 | Gao Lijing Xu Bo Xiao Guomin | 2008 | Energy & Fuels2008，22，： | 1 |
| 12 | lnfluence of structure and property of plasticizers on viscosity and aging process of PVC plastisols显示文摘 | Xu Guomin Ji Yubi Yang Zhao | 2012 | Applied Mechanics and Materials2012，161，： | 1 |
| 13 | An areal recharge and discharge simulating method for MODFLOW显示文摘 | Yanhui Dong Guomin Li Haizhen Xu | 2011 | Computers and Geosciences2011，，： | 1 |
| 14 | Effects of Different Flue-curing Technologies on Submicroscopic Structure of Flue-cured Tobacco Leaves显示文摘[Objective]This study aimed to compare the effects of low-temperature low-humidity tobacco flue-curing technology,moderate-temperature moderatehumidity tobacco flue-curing technology and moderate-temperature high-humidity tobacco flue-curing technology on submicroscopic structure of flue-cured tobacco leaves to provide theoretical basis for tobacco flue-curing. [Method] Middle leaves of tobacco cultivar K326 were collected in Pengshui County of Chongqing City for flue-curing experiment using three flue-curing technologies. Leaf samples were collected regularly in the flue-curing process,to investigate the submicroscopic structure of flue-cured tobacco leaves. [Result]Morphology changes and structural rupture of chloroplasts occurred at different time during three flue-curing processes. In low-temperature low-humidity flue-curing process,morphology changes and structural rupture of chloroplasts occurred late but rapidly; in moderate-temperature moderate-humidity flue-curing process and moderate-temperature high-humidity flue-curing process,morphology changes and structural rupture of chloroplasts occurred early but slowly. Among these three flue-curing processes,the speed of changes in mitochondria morphology,cristae number and membrane rupture presented an upward order of low-temperature low-humidity flue-curing process < moderate-temperature high-humidity flue-curing process < moderate-temperature moderate-humidity flue-curing process. In low-temperature low-humidity flue-curing process,starch granules in chloroplasts ruptured after flue-curing for 36- 48 h;in moderate-temperature moderate-humidity flue-curing process,starch granules in chloroplasts ruptured after flue-curing for 24- 36 h; in moderate-temperature high-humidity flue-curing process,starch granules in chloroplasts ruptured after flue-curing for 12- 24 h. [Conclusion]Using low-temperature low-humidity fluecuring technology could prolong the maintenance duration of the submicroscopic structure integrity of flue-cured tobacco leaves,which was conducive to fully decomposing and transforming substances in tobacco leaves and obtaining high-quality flue-cured tobacco leaves. | Guomin CUI Bojun WANG Rongchun LI Anding XU Yiyin CHEN Chao YANG Min PU | 2014 | Agricultural Biotechnology2014，3，1： | 1 |
| 15 | Effects of Different Flue-curing Technologies on Microscopic Structure of Flue-cured Tobacco Leaves显示文摘[Objective]This study aimed to compare the effects of Chinese quality-improving fragrance-increasing tobacco flue-curing technology,Chinese threestage tobacco flue-curing technology and Zimbabwean tobacco flue-curing technology on microscopic structure of flue-cured tobacco leaves to provide theoretical basis for tobacco flue-curing. [Method]Middle leaves of tobacco cultivar K326 were collected in Pengshui County of Chongqing City for flue-curing experiment using three flue-curing technologies. Leaf samples were collected regularly in the flue-curing process,to investigate the microscopic structure of flue-cured tobacco leaves.[Result]During three flue-curing processes,leaves,palisade tissues and sponge tissues shrank gradually. Three flue-curing processes exhibited significant differences in the peak of tissue shrinkage: microscopic structure of flue-cured tobacco leaves in Chinese three-stage tobacco flue-curing process shrank earliest,follower by Chinese quality-improving fragrance-increasing tobacco flue-curing process; flue-cured tobacco leaves in Zimbabwean tobacco flue-curing process presented the latest shrinkage. At 84 h post-curing,leaf thickness in three flue-curing processes showed a descend order of Chinese three-stage tobacco flue-curing process >Chinese quality-improving fragrance-increasing tobacco flue-curing process > Zimbabwean tobacco flue-curing process. Upper and lower epidermal cells in Zimbabwean tobacco flue-curing process ruptured earlier than other two flue-curing processes; eventually,the majority of cells ruptured and mixed with palisade tissues and sponge tissues. In Chinese quality-improving fragrance-increasing tobacco flue-curing process,only a small number of epidermal cells in dried leaves ruptured.Among three flue-curing technologies,Zimbabwean tobacco flue-curing technology exhibited the greatest damage to epidermal cells,followed by Chinese three-stage tobacco flue-curing technology; Chinese quality-improving fragrance-increasing tobacco flue-curing technology had the minimum damage to epidermal cells. Mesophyll cross-section exhibited significant morphological changes in stomata. To be specific,at 0- 12 h post-curing,stomata of tobacco leaves closed with slightly prominent stomatal apparatuses on upper and lower epidermis; at 24- 72 h post-curing,stomata of tobacco leaves changed gradually from opening to closure with significantly prominent stomatal apparatuses on upper and lower epidermis; at 84 h post-curing,stomata of tobacco leaves closed,and the majority of stomatal apparatuses were significantly prominent. In Chinese quality-improving fragrance-increasing tobacco flue-curing process,only a small number of epidermal cells ruptured at 84 h post-flue-curing; palisade tissues and sponge tissues shrank almost simultaneously. Significant gaps were observed between palisade tissues and between palisade tissues and sponge tissues. Chinese quality-improving fragrance-increasing tobacco flue-curing technology exhibited lower disorder level compared with other two flue-curing technologies. [Conclusion]Chinese quality-improving fragrance-increasing tobacco flue-curing technology was conducive to maintaining the microscopic structure integrity of flue-cured tobacco leaves and obtaining high-quality flue-cured tobacco leaves. | Guomin CUI Bojun WANG Rongchun LI Anding XU Yiyin CHEN Chao YANG Min PU | 2014 | Agricultural Biotechnology2014，3，2： | 1 |
| 16 | Transesterification of Palm Oil with Methanol to Biodiesel over a KF/AI203 Het- erogeneous Base Catalyst 显示文摘 | Xu Bo Xiao Guomin Cui Lingfeng | 2007 | Energy Fuels2007，21，6： | 1 |
| 17 | Transesterification of Palm Oil with Methanol to Biodiesel over a KF/Hydrotalcite Solid Catalyst 显示文摘 | Gao Lijing Xu Bo Xiao Guomin | 2008 | Energy Fuels2008，22，5： | 1 |
| 18 | SARS-CoV-2 Aerosol Transmission Through Vertical Sanitary Drains in High-Rise Buildings--Shenzhen,Guangdong Province,China,March 2022显示文摘Summary What is already known about this topic?Aerosol transmission of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)via sanitary pipelines in high-rise buildings is possible,however,there is a lack of experimental evidence. | Keyang Lyu Siyang Feng Xia Li Qin Wang Xiaoning Zhao Shuyuan Yu Ping Zheng Jiajia Ji Guomin Chen Jing Liang Tao Lan Jinshu Feng Shuai Jiang Jianhua Lu Tianlong Xia Chaoqiong Peng Tiejian Feng Dongqun Xu | 2022 | China CDC weekly2022，4，23： | 1 |
| 19 | Transesterification of Cottonseed Oil to Biodiesel by Using Heterogeneous Solid Basic Catalysts 显示文摘 | Cui Lingfeng Xiao Guomin Xu Bo | 2007 | Energy & Fuels2007，，21： | 1 |
| 20 | Identification of medicinal vines by ITS2 using complementary discrimination methods显示文摘 | Zhihua Liu Xu Zeng Dan Yang Guomin Ren Guiyan Chu Zhengrong Yuan Kun Luo Peigen Xiao Shilin Chen | 2012 | Journal of Ethnopharmacology2012，，1： | 1 |
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