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| 1 | Role of mantle-derived magma in genesis of early Yanshanian granites in the Nanling Range, South China: in situ zircon Hf-O isotopic constraints显示文摘Although a number of petrographic observations and isotopic data suggest that magma mixing is common in genesis of many granite plutons, it is still controversial whether the mantle-derived magmas were involved in granites. We carried out in this study a systematic analysis of in situ zircon Hf-O isotopes for three early Yanshanian intrusions dated at ca. 160 Ma from the Nanling Range of Southeast China. The Qinghu monzonite has very homogeneous zircon Hf-O isotopic compositions, εHf(t) =11.6±0.3 and δ18O=5.4‰±0.3‰. In combination with whole-rock geochemical and Sr-Nd isotopic data, the parental magma of the Qinghu monzonite were likely derived from the partial melting of recently-metasomatized, phlogopite-bearing lithospheric mantle without appreciable crustal contamination. The Lisong and Fogang granites and the mafic microgranular enclaves (MME) within the Lisong granites have a wide range of zircon Hf-O isotopic compositions, with Hf and O isotopes being negatively correlated within each pluton. The Lisong MMEs were crystallized from a mantle-derived magma, similar to the parental magma of the Qinghu monzonite, with small amount of crustal assimilation. The Lisong and Fogang granites were formed by reworking of meta-sedimentary materials by mantle-derived magmas and mixing of the mantle-and sediment-derived melts to varying degrees. It is thus concluded that these two Yanshanian granites in the Nanling Range were formed associated with growth and differentiation of continental crust. | LI XianHua LI WuXian WANG XuanCe LI QiuLi LIU Yu TANG GuoQiang | 2009 | Science China Earth Sciences2009，52，9： | 101 |
| 2 | Periodicity of Holocene climatic variations in the Huguangyan Maar Lake显示文摘There exist five primary periods of 2 930, 1 140, 490, 250 and 220 a in the Holocene climatic variations in the Huguangyan Maar Lake, according to the energy-spectrum and filter analyses of high-resolution time sequences (10-15 a) of the sediment dry density. The peak values of the three temperature-decreasing periods with the 2 930 a cycle occur at about 7 300, 4 250 and 1 200 Cal. aBP. There are 7-8 temperature-decreasing periods with the 1 140 a cycle, and the climate fluctuation range is largest in the early Holocene, and reduces gradually in the middle and late Holocene. The millennial-scale climatic change in the Holocene may adjust the global water cycle and the thermohaline circulation intensity through the harmonic tones of the earth’s precession cycle, which in turn influences the global climate change. | LIU Jiaqi LÜ Houyuan JNegendank JMingram LUO Xiangjun WANG Wenyuan CHU Guoqiang | 2000 | Chinese Science Bulletin2000，45，18： | 33 |
| 3 | A journey to understand wheat Fusarium head blight resistance in the Chinese wheat landrace Wangshuibai显示文摘Fusarium head blight(FHB) or scab caused by Fusarium graminearum is a major threat to wheat production in China as well as in the world. To combat this disease, multiple efforts have been carried out internationally. In this article, we review our long-time effort in identifying the resistance genes and dissecting the resistance mechanisms by both forward and reverse genetics approaches in the last two decades. We present recent progress in resistance QTL identification, candidate functional gene discovery, marker-assisted improvement of FHB resistant varieties, and findings in investigating association of signal molecules, such as Ca^(++),SA, JA, and ET, with FHB response, with the assistance from rapidly growing genomics platforms. The information will be helpful for designing novel and efficient approaches to curb FHB. | Haiyan Jia Jiyang Zhou Shulin Xue Guoqiang Li Haisheng Yan Congfu Ran Yiduo Zhang Jinxing Shi Li Jia Xin Wang Jing Luo Zhengqiang Ma | 2018 | The Crop Journal2018，6，1： | 24 |
| 4 | Sequencing of Cultivated Peanut, Arachis hypogaea, Yields Insights into Genome Evolution and Oil Improvement显示文摘Cultivated peanut (Arachis hypogaea) is an allotetraploid crop planted in Asia, Africa, and America for edible oil and protein. To explore the origins and consequences of tetraploidy, we sequenced the allotetraploid A. hypogaea genome and compared it with the related diploid Arachis duranensis and Arachis ipaensis genomes. We annotated 39 888 A-subgenome genes and 41 526 B-subgenome genes in allotetraploid peanut. The A. hypogaea subgenomes have evolved asymmetrically, with the B subgenome resembling the ancestral state and the A subgenome undergoing more gene disruption, loss, conversion, and transposable element proliferation, and having reduced gene expression during seed development despite lacking genome-wide expression dominance. Genomic and transcriptomic analyses identified more than 2 500 oil metabolism-related genes and revealed that most of them show altered expression early in seed development while their expression ceases during desiccation, presenting a comprehensive map of peanut lipid biosynthesis. The availability of these genomic resources will facilitate a better understanding of the complex genome architecture, agronomically and economically important genes, and genetic improvement of peanut. | Xiaoping Chen Qing Lu Hao Liu Jianan Zhang Yanbin Hong Haofa Lan Haifen Li Jinpeng Wang Haiyan Liu Shaoxiong Li Manish K.Pandey Zhikang Zhang Guiyuan Zhou Jigao Yu Guoqiang Zhang Jiaqing Yuan Xingyu Li Shijie Wen Fanbo Meng Shanlin Yu Xiyin Wang Kadambot H.M.Siddique Zhong-Jian Liu Andrew H.Paterson Rajeev K.Varshney Xuanqiang Liang | 2019 | Molecular Plant2019，12，7： | 23 |
| 5 | Visualization Experiments of a Specific Fuel Flow Through Quartz-glass Tubes Under both Sub- and Supercritical Conditions显示文摘The present work is a visualization study of a typical kerosene (RP-3) flowing through vertical and horizontal quartz-glass tubes under both suband supercritical conditions by a high speed camera. The experiments are accomplished at temperatures of 300-730 K under pressures from 0.107-5 MPa. Six distinctive two-phase flow patterns are observed in upward flow and the critical point of RP-3 is identified as critical pressure pc=2.33 MPa and critical temperature Tc=645.04 K and it is found that when the fluid pressure exceeds 2.33 MPa the flow can be considered as a single phase flow. The critical opalescence phenomenon of RP-3 is observed when the temperature is between 643.16 K and 648.61 K and the pressure is between 2.308 MPa and 2.366 MPa. The region filled by the critical opalescence in the upward flow is clearly larger than that in the downward flow due to the interaction between the buoyancy force and fluid inertia. Morecover, obvious layered flow phenomenon is observed in horizontal flow under supercritical pressures due to the differences of gravity and density. | DENG Hongwu ZHANG Chunben XU Guoqiang TAO Zhi ZHU Kun WANG Yingjie | 2012 | Chinese Journal of Aeronautics2012，25，3： | 18 |
| 6 | Fracture detection by using full azimuth P wave attributes显示文摘特定的折断的烃水库的一种类型,页岩折断了水库,在 Shengli 油矿存在。由于这种类型,到石油化学的性质参数的变化的低敏感,和强壮的 anisotropy 的很小的孔,为他们探索是很困难的。到目前为止,没有为由综合分析的破裂的方向,分发,和密度的识别的成熟方法的集合地质,地球物理,井木头,钻的数据,和等等。这篇论文与方位角(IPVA ) 为声学的阻抗变化论述一个新方法,基于存在破裂察觉方法。地震获得,处理,并且识别技术为在 Luojia 区域与页岩破裂的地震、地质的特征在联合用多方位角 P 波浪数据检测方向性的垂直破裂被开发。IPVA 研究为认识到基于有方位角(VVA ) 的速度变化和有为完整的方位角 P 的方位角(AVA ) 的振幅变化的学习的破裂的分发,罢工,和密度在不同 CMP 位置挥动数据被执行。通过在 Luojia 区域的实际申请,主要结果被获得了它证实 IPVA 方法为平行、高角度的量的察觉提供好潜力,页岩破裂。 | Qu Shouli Ji Yuxin Wang Xin Wang Xiuling Chen xinrong Shen Guoqiang | 2007 | Applied Geophysics2007，4，3： | 15 |
| 7 | Efficacy and safety evaluation of intravenous infusion of cervus and cucumis polypeptides for treatment of avascular necrosis of the femoral head: a randomized clinical trial显示文摘OBJECTIVE: To investigate the efficacy and safety of intravenous cervus and cucumis polypeptides for treating avascular necrosis of the femoral head(ANFH) in regard to pain and hip function in a randomized clinical trial.METHODS: A total of 96 subjects with ANFH who were recruited at the Orthopaedic Hospital Affiliated with Hebei United University and Qian Hai Femoral Head Hospital of Beijing were assigned by lottery to an intervention group(n = 48) or a control group(n = 48). All subjects underwent physical therapy and rehabilitation exercises. In addition,subjects in the intervention group were given intravenous infusions of cervus and cucumis polypeptides. Visual analogue scale(VAS), Harris hip score,and radiography or magnetic resonance imaging were applied to assess all subjects at the beginning of treatment and 3, 6, and 9 months afterward. All the subjects were followed up for 2 years.RESULTS: At the beginning of treatment, there were no statistically significant differences between the two groups in terms of the general condition of patients or the VAS and Harris hip scores(all P > 0.05). At 3, 6, and 9 months after treatment,however, the VAS score decreased and the Harris hip score increased in all patients, with the improvement of intervention group significantly greater than that of the control group(P < 0.05).The total effectiveness rates for the intervention and control groups were 89.58% and 70.83%, respectively, with the difference being statistically significant(P < 0.05). There was no statistically significant difference between the two groups in terms of the safety of the injections(P > 0.05).CONCLUSION: Intravenous infusion of cervus and cucumis polypeptides relieved pain and improved hip function of subjects with ANFH.Thus, the intravenous infusion of cervus and cucumis polypeptides was a safe, effective treatment for ANFH. | Wei Liyou Zhang Hongwei Li Xinmin Yang Chunyan Wang Guoqiang Zhang Lifeng Cui Mingwu Han Lijun | 2016 | Journal of Traditional Chinese Medicine2016，36，1： | 15 |
| 8 | Effect of Trichoderma viride biofertilizer on ammonia volatilization from an alkaline soil in Northern China显示文摘Ammonia(NH3) volatilization is one of the primary pathways of nitrogen(N) loss from soils after chemical fertilizer is applied, especially from the alkaline soils in Northern China, which results in lower efficiency for chemical fertilizers. Therefore, we conducted an incubation experiment using an alkaline soil from Tianjin(p H 8.37–8.43) to evaluate the suppression effect of Trichoderma viride(T. viride) biofertilizer on NH3 volatilization, and compared the differences in microbial community structure among all samples. The results showed that viable T. viride biofertilizer(T) decreased NH_3 volatilization by 42.21% compared with conventional fertilizer((CK), urea), while nonviable T. viride biofertilizer(TS) decreased NH_3 volatilization by 32.42%. NH_3 volatilization was significantly higher in CK and sweet potato starch wastewater(SPSW) treatments during the peak period. T. viride biofertilizer also improved the transfer of ammonium from soil to sweet sorghum. Plant dry weights increased 91.23% and 61.08% for T and TS, respectively, compared to CK. Moreover, T. viride biofertilizer enhanced nitrification by increasing the abundance of ammonium-oxidizing archaea(AOA) and ammonium-oxidizing bacteria(AOB). The results of high-throughput sequencing indicated that the microbial community structure and composition were significantly changed by the application of T. viride biofertilizer. This study demonstrated the immense potential of T. viride biofertilizer in reducing NH_3 volatilization from alkaline soil and simultaneously improving the utilization of fertilizer N by sweet sorghum. | Xia Wang Shengjun Xu Shanghua Wu Shugeng Feng Zhihui Bai Guoqiang Zhuang Xuliang Zhuang | 2018 | Journal of Environmental Sciences2018，30，4： | 15 |
| 9 | Lycorine inhibits the growth and metastasis of breast cancer through the blockage of STAT3 signaling pathway显示文摘 | Jian Wang Jie Xu Guoqiang Xing | 2017 | Acta Biochimica et Biophysica Sinica2017，49，9： | 14 |
| 10 | Impacts of Climatic Factors on Runoff Coefficients in Source Regions of the Huanghe River显示文摘Runoff coefficients of the source regions of the Huanghe River in 1956–2000 were analyzed in this paper. In the 1990s runoff of Tangnaihai Hydrologic Station of the Huanghe River experienced a serious decrease, which had at- tracted considerable attention. Climate changes have important impact on the water resources availability. From the view of water cycling, runoff coefficients are important indexes of water resources in a particular catchment. Kalinin baseflow separation technique was improved based on the characteristics of precipitation and streamflow. After the separation of runoff coefficient (R/P), baseflow coefficient (Br/P) and direct runoff coefficient (Dr/P) were estimated. Statistic analyses were applied to assessing the impact of precipitation and temperature on runoff coefficients (including Dr/P, Br/P and R/P). The results show that in the source regions of the Huanghe River, mean annual baseflow coefficient was higher than mean annual direct runoff coefficient. Annual runoff coefficients were in direct proportion to annual pre- cipitation and in inverse proportion to annual mean temperature. The decrease of runoff coefficients in the 1990s was closely related to the decrease in precipitation and increase in temperature in the same period. Over different sub-basins of the source regions of the Huanghe River, runoff coefficients responded differently to precipitation and temperature. In the area above Jimai Hydrologic Station where annual mean temperature is –3.9oC, temperature is the main factor in- fluencing the runoff coefficients. Runoff coefficients were in inverse relation to temperature, and precipitation had nearly no impact on runoff coefficients. In subbasin between Jimai and Maqu Hydrologic Station Dr/P was mainly affected by precipitation while R/P and Br/P were both significantly influenced by precipitation and temperature. In the area be-tween Maqu and Tangnaihai hydrologic stations all the three runoff coefficients increased with the rising of annual precipitation, while direct runoff coefficient was inversely proportional to temperature. In the source regions of the Huanghe River with the increase of average annual temperature, the impacts of temperature on runoff coefficients be-come insignificant. | CHEN Liqun LIU Changming LI Yanping WANG Guoqiang | 2007 | Chinese Geographical Science2007，17，1： | 12 |
| 11 | The program structure designing and optimizing tests of GRAPES physics显示文摘According to the modularization and standardization of program structure in Global/Regional Assimilation and Prediction System (GRAPES), the plug-compatible and transplantable regional meso-scale and global middle-range physics software package is established. The package's component integrality is comparative with the other advanced models physics. A three-level structure of connecting GRAPES physics and dynamic frame has been constructed. The friendly interface is designed for users to plug in their own physics packages. Phenomenon of grid-point storm rainfall in numerical prediction is analyzed with the numerical tests. The scheme of air vertical velocity calculation is improved. Optimizing tests of physics schemes are performed with the correlative parameters adjusting. The results show that the false grid-point storm rainfall is removed by precipitation scheme improving. Then the score of precipitation forecast is enhanced. | XU GuoQiang CHEN DeHui XUE JiShan SUN Jian SHEN XueShun SHEN YuanFang HUANG LiPing WU XiangJun ZHANG HongLiang WANG ShiYu | 2008 | Chinese Science Bulletin2008，53，22： | 11 |
| 12 | Analysis of bacterial community in bulking sludge using culture-dependent and -independent approaches显示文摘The bacterial community of a bulking sludge from a municipal wastewater treatment plant with anoxic-anaerobic-oxic process was investigated by combination of cultivation and 16S rRNA gene clone library analysis for understanding the causes of bulking.A total of 28 species were obtained from 63 isolates collected from six culture media.The most cultivable species belonged to γ-Proteobacteria including Klebsiella sp.,Pseudomonas sp.,Aeromonas sp.and Acinetobacter sp.Further analysis of these strains by repetitive sequence based on polymerase chain reaction (rep-PCR) technology showed that rep-PCR yielded discriminatory banding patterns within the same genus using REP and BOX primer sets.While the culture-independent assessment revealed that β-Proteobacteria was the dominant group in the bulking sample.Sequence analysis revealed that the highest proportion (14.7%) of operational taxonomic units was 98% similar to Candidatus Accumulibacter phosphatis,which is used to remove phosphorous from wastewater.Our results indicated that combining different approaches can produce complementary information,thus generate a more accurate view of microbial community in bulking sludge. | Decai Jin Ping Wang Zhihui Bai Xinxin Wang Hong Peng Rong Qi Zhisheng Yu Guoqiang Zhuang | 2011 | Journal of Environmental Sciences2011，23，11： | 11 |
| 13 | Effects of Forest Type and Urbanization on Carbon Storage of Urban Forests in Changchun, Northeast China显示文摘Rapid urbanization has led to dramatic changes in urban forest structures and functions, and consequently affects carbon(C) storage in cities. In this study, field surveys were combined with high resolution images to investigate the variability of C storage of urban forests in Changchun, Northeast China. The main objectives of this study were to quantify the C storage of urban forests in Changchun City, Northeast China and understand the effects of forest type and urbanization on C storage of urban forests. The results showed that the mean C density and the total C storage of urban forests in Changchun were 4.41 kg/m2 and 4.74 × 108 kg, respectively. There were significant differences in C density among urban forest types. Landscape and relaxation forest(LF) had the highest C density with 5.41 kg/m2, while production and management forest(PF) had the lowest C density with 1.46 kg/m2. These differences demonstrate that urban forest type is an important factor needed to be considered when the C storage is accurately estimated. Further findings revealed significant differences in different gradients of urbanization, and the mean C density decreased from the first ring(6.99 kg/m2) to the fourth ring(2.87 kg/m2). The total C storage increased from the first ring to the third ring. These results indicate that C storage by urban forests will be significantly changed during the process of urbanization. The results can provide insights for decision-makers and urban planners to better understand the effects of forest type and urbanization on C storage of urban forests in Changchun, and make better management plans for urban forests. | ZHANG Dan ZHENG Haifeng REN Zhibin ZHAI Chang SHEN Guoqiang MAO Zhixia WANG Peijiang HE Xingyuan | 2015 | Chinese Geographical Science2015，25，2： | 9 |
| 14 | Aeration optimization through operation at low dissolved oxygen concentrations:Evaluation of oxygen mass transfer dynamics in different activated sludge systems显示文摘In wastewater treatment plants(WWTPs)using the activated sludge process,two methods are widely used to improve aeration efficiency — use of high-efficiency aeration devices and optimizing the aeration control strategy. Aeration efficiency is closely linked to sludge characteristics(such as concentrations of mixed liquor suspended solids(MLSS)and microbial communities)and operating conditions(such as air flow rate and operational dissolved oxygen(DO)concentrations). Moreover,operational DO is closely linked to effluent quality. This study,which is in reference to WWTP discharge class A Chinese standard effluent criteria,determined the growth kinetics parameters of nitrifiers at different DO levels in small-scale tests. Results showed that the activated sludge system could meet effluent criteria when DO was as low as 0.3 mg/L,and that nitrifier communities cultivated under low DO conditions had higher oxygen affinity than those cultivated under high DO conditions,as indicated by the oxygen half-saturation constant and nitrification ability. Based on nitrifier growth kinetics and on the oxygen mass transfer dynamic model(determined using different air flow rate(Q′_(air))and mixed liquor volatile suspended solids(MLVSS)values),theoretical analysis indicated limited potential for energy saving by improving aeration diffuser performance when the activated sludge system had low oxygen consumption; however,operating at low DO and low MLVSS could significantly reduce energy consumption. Finally,a control strategy coupling sludge retention time and MLVSS to minimize the DO level was discussed,which is critical to appropriate setting of the oxygen point and to the operation of low DO treatment technology. | Haitao Fan Lu Qi Guoqiang Liu Yuankai Zhang Qiang Fan Hongchen Wang | 2017 | Journal of Environmental Sciences2017，29，5： | 9 |
| 15 | Wheat genomic study for genetic improvement of traits in China显示文摘Bread wheat(Triticum aestivum L.)is a major crop that feeds 40%of the world’s population.Over the past several decades,advances in genomics have led to tremendous achievements in understanding the origin and domestication of wheat,and the genetic basis of agronomically important traits,which promote the breeding of elite varieties.In this review,we focus on progress that has been made in genomic research and genetic improvement of traits such as grain yield,end-use traits,flowering regulation,nutrient use efficiency,and biotic and abiotic stress responses,and various breeding strategies that contributed mainly by Chinese scientists.Functional genomic research in wheat is entering a new era with the availability of multiple reference wheat genome assemblies and the development of cutting-edge technologies such as precise genome editing tools,highthroughput phenotyping platforms,sequencing-based cloning strategies,high-efficiency genetic transformation systems,and speed-breeding facilities.These insights will further extend our understanding of the molecular mechanisms and regulatory networks underlying agronomic traits and facilitate the breeding process,ultimately contributing to more sustainable agriculture in China and throughout the world. | Jun Xiao Bao Liu Yingyin Yao Zifeng Guo Haiyan Jia Lingrang Kong Aimin Zhang Wujun Ma Zhongfu Ni Shengbao Xu Fei Lu Yuannian Jiao Wuyun Yang Xuelei Lin Silong Sun Zefu Lu Lifeng Gao Guangyao Zhao Shuanghe Cao Qian Chen Kunpu Zhang Mengcheng Wang Meng Wang Zhaorong Hu Weilong Guo Guoqiang Li Xin Ma Junming Li Fangpu Han Xiangdong Fu Zhengqiang Ma Daowen Wang Xueyong Zhang Hong-Qing Ling Guangmin Xia Yiping Tong Zhiyong Liu Zhonghu He Jizeng Jia Kang Chong | 2022 | Science China(Life Sciences)2022，65，9： | 9 |
| 16 | Sumoylation of hypoxia inducible factor-1α and its significance in cancer显示文摘Hypoxia-inducible factor-1(HIF-1)is a key heterodimeric transcription factor for the cellular adaptive response to hypoxia,a common feature of the microenvironment in solid tumors.The transcriptional activity,protein stabilization,protein-protein interactions and cellular localization of HIF-1α,an oxygen-sensitive subunit of HIF-1,are mainly modulated by various post-translational modifications.Recently,we reported that polycomb chromobox 4(Cbx4)governs the transcriptional activity of HIF-1αby enhancing its sumoylation at K391 and K477,through which Cbx4 potentiates angiogenesis of hepatocellular carcinoma.This review summarizes the current knowledge of HIF-1α sumoylation and its roles in the pathogenesis of cancer. | LI Jie XU Ying JIAO HuiKe WANG Wei MEI Zhu CHEN GuoQiang | 2014 | Science China(Life Sciences)2014，57，7： | 9 |
| 17 | Polycomb chromobox 4 enhances migration and pulmonary metastasis of hepatocellular carcinoma cell line MHCC97L显示文摘We recently report that the expression of polycomb chromobox 4(Cbx4)is significantly correlated with the overall survival of a great cohort of hepatocellular carcinoma(HCC)patients and it enhances hypoxia-induced vascular endothelial growth factor(VEGF)expression and angiogenesis in HCC cells through enhancing sumoylation of hypoxia inducible factor-1alpha(HIF-1α).Here we continue to investigate the potential effects of Cbx4 on the migration and metastasis of the metastatic HCC cell line MHCC97L.Our results show that Cbx4 overexpression in the cell line increases the in vitro vessel formation of vascular endothelial cells in its SUMO interaction motifs-dependent manner,and promotes the in vitro migration of the cancer cell,which can be effectively abrogated by anti-VEGF antibody.Although Cbx4 expression does not impact the in vitro growth of MHCC97L cells,it still promotes the progression and metastasis of orthotopically transplanted tumors in nude mice.These results further support the role of Cbx4 as a SUMO E3 ligase in the progression and metastasis of HCC. | MEI Zhu JIAO HuiKe WANG Wei LI Jie CHEN GuoQiang XU Ying | 2014 | Science China(Life Sciences)2014，57，6： | 9 |
| 18 | Lipogenesis in myoblasts and its regulation of CTRP6 by AdipoR1/Erk/PPARγ signaling pathway显示文摘在 C2C12 myoblasts 的导致的 lipogenesis 和它的规定仍然保持大部分不清楚。这里,我们发现鸡尾酒 methodcould 显著地通过调整类脂化合物导致 lipogenesis 在 myoblasts 的新陈代谢的基因和 Erk1/2 phosphorylation。同时, CTRP6 的表示和分泌物在宫外的 lipogenesis 期间被增加。而且, CTRP6 击倒下面调整 lipogenic 基因的层次和在早 lipogenic 的 phosphorylated Erk1/2 (p-Erk1/2 ) 上演,而在终端区别的起来调整的 p-Erk1/2。有趣地, CTRP6 siRNA 的效果在 myoblasts 是稀释 byU0126 (一个特殊 p-Erk1/2 禁止者) 。而且, AdipoR1,不是 AdipoR2,首先在有丝分裂的同种细胞的扩大的过程期间作为受体 ofCTRP6 被识别。一起,我们建议 CTRP6 调停通过在 myoblasts 表明小径的 AdipoR1/Erk/PPAR 的宫外的 lipogenesis。我们的调查结果将流轻在小说生物在 myoblast lipogenesis 期间 CTRP6 工作并且提供由 lipogenic regulationin 改进家畜的肉质量的一个有希望的方向骨胳的肌肉 myoblasts。 | Wenjing Wu Yunmei Sun Chen Zhao Cunzhen Zhao Xiaochang Chen Guoqiang Wang Weijun Pang Gongshe Yang | 2016 | Acta Biochimica et Biophysica Sinica2016，48，6： | 9 |
| 19 | Optimal search for moving targets with sensing capabilities using multiple UAVs显示文摘This paper studies the problem of using multiple unmanned air vehicles(UAVs) to search for moving targets with sensing capabilities. When multiple UAVs(multi-UAV) search for a number of moving targets in the mission area, the targets can intermittently obtain the position information of the UAVs from sensing devices, and take appropriate actions to increase the distance between themselves and the UAVs. Aiming at this problem, an environment model is established using the search map, and the updating method of the search map is extended by considering the sensing capabilities of the moving targets. A multi-UAV search path planning optimization model based on the model predictive control(MPC) method is constructed, and a hybrid particle swarm optimization algorithm with a crossover operator is designed to solve the model. Simulation results show that the proposed method can effectively improve the cooperative search efficiency and can find more targets per unit time compared with the coverage search method and the random search method. | Xiaoxuan Hu Yanhong Liu Guoqiang Wang | 2017 | Journal of Systems Engineering and Electronics2017，28，3： | 8 |
| 20 | Poly(methyl methacrylate) bone cement composited with mineralized collagen for osteoporotic vertebral compression fractures in extremely old patients显示文摘To examine the clinical effects of a new bone cement composed of poly(methyl methacrylate)(PMMA)and mineralized collagen(MC)compared with pure PMMA bone cement in treating osteoporotic vertebral compression fractures(OVCFs)in patients aged over 80.In all,32 cases using pure PMMA bone cement and 31 cases using MC-modified PMMA(MC-PMMA)bone cement for OVCFs between June 2014 and March 2016 were screened as PMMA group and MC-PMMA group,respectively,with an average age of over 80.The operation duration,intraoperative blood loss,hospital stay,oswestry disability index(ODI),visual analogue scale(VAS),anterior vertebral height(AVH),intermediate vertebral height(IVH)and posterior vertebral height(PVH)of injured vertebrae,vertebral computed tomography value,re-fracture rate of adjacent vertebrae,correction rate of spinal kyphotic angle and wedge-shaped vertebra angle and surgical complications were compared between the two groups.In the early post-operative period,the VAS,ODI,AVH and IVH in MC-PMMA group were comparable to those in the traditional PMMA group.Moreover,the MC-PMMA group showed better effects compared with the PMMA group 12months after surgery.Thus,this new bone cement has superior clinic effects in the long term. | Kefeng Luo Guoqiang Jiang Jinjin Zhu Bin Lu Jiye Lu Kai Zhang Xiumei Wang Fu-Zhai Cui | 2020 | Regenerative Biomaterials2020，7，1： | 8 |
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